Martin Borch Jensen
@martinbjensen.bsky.social
Aging, Systems Biology, Gene Therapy. CSO @GordianBio, doing mosaic therapeutic screens in vivo.
Also @NornGroup/Impetus Grants. Previously K99 Fellow @Buck Institute.
Also @NornGroup/Impetus Grants. Previously K99 Fellow @Buck Institute.
Reposted by Martin Borch Jensen
E11 Bio is excited to unveil PRISM technology for mapping brain wiring with simple light microscopes. Today, brain mapping in humans and other mammals is bottlenecked by accurate neuron tracing. PRISM uses molecular ID codes and AI to help neurons trace themselves.
Read more: e11.bio/blog/prism
Read more: e11.bio/blog/prism
October 1, 2025 at 2:16 PM
E11 Bio is excited to unveil PRISM technology for mapping brain wiring with simple light microscopes. Today, brain mapping in humans and other mammals is bottlenecked by accurate neuron tracing. PRISM uses molecular ID codes and AI to help neurons trace themselves.
Read more: e11.bio/blog/prism
Read more: e11.bio/blog/prism
Notes from an excellent aging conference on the @norngroup.bsky.social substack: norngroup.substack.com/p/field-note...
Field notes: ARDD 2025
An exciting aging conference (w 995 schedule + drinks... thanks CH+DK organizers). Pharma paying attention to longevity like never before. New mega-institute. Clinical trials reading out end of year.
norngroup.substack.com
September 2, 2025 at 2:27 PM
Notes from an excellent aging conference on the @norngroup.bsky.social substack: norngroup.substack.com/p/field-note...
Reposted by Martin Borch Jensen
The "reproducibility crisis" in science constantly makes headlines. Repro efforts are often limited. What if you could assess reproducibility of an entire field?
That's what @brunolemaitre.bsky.social et al. have done. Fly immunity is highly replicable & offers lessons for #metascience
A 🧵 1/n
That's what @brunolemaitre.bsky.social et al. have done. Fly immunity is highly replicable & offers lessons for #metascience
A 🧵 1/n
July 10, 2025 at 8:23 AM
The "reproducibility crisis" in science constantly makes headlines. Repro efforts are often limited. What if you could assess reproducibility of an entire field?
That's what @brunolemaitre.bsky.social et al. have done. Fly immunity is highly replicable & offers lessons for #metascience
A 🧵 1/n
That's what @brunolemaitre.bsky.social et al. have done. Fly immunity is highly replicable & offers lessons for #metascience
A 🧵 1/n
Like the DNA of an organism, the Constitution assembled around itself a vast substrate, of people chasing dreams and stumbling on the way, of physical transformation, of thoughts that bend history.
As complex life arises from simple nutrients, so does a land of opportunity arise from simple ideas.
As complex life arises from simple nutrients, so does a land of opportunity arise from simple ideas.
July 4, 2025 at 7:40 PM
Like the DNA of an organism, the Constitution assembled around itself a vast substrate, of people chasing dreams and stumbling on the way, of physical transformation, of thoughts that bend history.
As complex life arises from simple nutrients, so does a land of opportunity arise from simple ideas.
As complex life arises from simple nutrients, so does a land of opportunity arise from simple ideas.
Reposted by Martin Borch Jensen
In 1 month, BEACON has already reported 181 disease events & 381 individual reports.
We're excited to announce that starting June 2nd, BEACON will be sending a free Weekly Disease Event Digest on Mondays to help you stay informed about emerging threats globally. Sign up below!
We're excited to announce that starting June 2nd, BEACON will be sending a free Weekly Disease Event Digest on Mondays to help you stay informed about emerging threats globally. Sign up below!
Starting on Monday, BEACON will be sending a weekly Disease Event Digest newsletter with summaries of infectious disease events over the previous week from around the world.
If you haven’t signed up yet, subscribe here:
http://spr.ly/63324NfQh8
If you haven’t signed up yet, subscribe here:
http://spr.ly/63324NfQh8
May 30, 2025 at 8:57 PM
In 1 month, BEACON has already reported 181 disease events & 381 individual reports.
We're excited to announce that starting June 2nd, BEACON will be sending a free Weekly Disease Event Digest on Mondays to help you stay informed about emerging threats globally. Sign up below!
We're excited to announce that starting June 2nd, BEACON will be sending a free Weekly Disease Event Digest on Mondays to help you stay informed about emerging threats globally. Sign up below!
For anyone who wants to understand how medicines are made, from nature and by design, with historical context and amazing stories, The Drug Hunters is hard to beat: www.amazon.com/dp/162872718...
Drug Hunters: The Improbable Quest to Discover New Medicines
Drug Hunters: The Improbable Quest to Discover New Medicines [Kirsch, Donald R., Ogas, Ogi] on Amazon.com. *FREE* shipping on qualifying offers. Drug Hunters: The Improbable Quest to Discover New Medicines
www.amazon.com
May 27, 2025 at 6:37 PM
For anyone who wants to understand how medicines are made, from nature and by design, with historical context and amazing stories, The Drug Hunters is hard to beat: www.amazon.com/dp/162872718...
Reposted by Martin Borch Jensen
people get mad at me when I say this but it's a Serious Problem for bluesky's long-term viability that the userbase actively tries to bully people they don't like off here
The problem is that Bluesky is still a niche platform at 1.3 Mil active users per day globally. Getting your boss to say yes to making an account and dedicating the time and effort to maintaining it means they need to see positives for that investment. A middle finger isn’t a good return.
May 26, 2025 at 4:06 AM
people get mad at me when I say this but it's a Serious Problem for bluesky's long-term viability that the userbase actively tries to bully people they don't like off here
Reposted by Martin Borch Jensen
Hopefully things change here, as my big worry about AI talk on this site is that people are being misled about the capabilities of AI by influencers who are telling them what they want to hear.
AI is not going away, it will impact all of our futures, and it needs more voices shaping its direction.
AI is not going away, it will impact all of our futures, and it needs more voices shaping its direction.
May 26, 2025 at 4:29 AM
Hopefully things change here, as my big worry about AI talk on this site is that people are being misled about the capabilities of AI by influencers who are telling them what they want to hear.
AI is not going away, it will impact all of our futures, and it needs more voices shaping its direction.
AI is not going away, it will impact all of our futures, and it needs more voices shaping its direction.
Reposted by Martin Borch Jensen
After consideration, I will post occasionally, but heavily censor what I share compared to other sites.
I tried making the transition, but talking about AI here is just really fraught in ways that are tough to mitigate & make it hard to have good discussions (the point of social!). Maybe it changes
I tried making the transition, but talking about AI here is just really fraught in ways that are tough to mitigate & make it hard to have good discussions (the point of social!). Maybe it changes
May 26, 2025 at 4:25 AM
After consideration, I will post occasionally, but heavily censor what I share compared to other sites.
I tried making the transition, but talking about AI here is just really fraught in ways that are tough to mitigate & make it hard to have good discussions (the point of social!). Maybe it changes
I tried making the transition, but talking about AI here is just really fraught in ways that are tough to mitigate & make it hard to have good discussions (the point of social!). Maybe it changes
Reposted by Martin Borch Jensen
The problem is that Bluesky is still a niche platform at 1.3 Mil active users per day globally. Getting your boss to say yes to making an account and dedicating the time and effort to maintaining it means they need to see positives for that investment. A middle finger isn’t a good return.
May 26, 2025 at 3:40 AM
The problem is that Bluesky is still a niche platform at 1.3 Mil active users per day globally. Getting your boss to say yes to making an account and dedicating the time and effort to maintaining it means they need to see positives for that investment. A middle finger isn’t a good return.
Reposted by Martin Borch Jensen
This news should instill urgency and remind us to ask ‘why not sooner?’.
@martinbjensen.bsky.social shared a long-term vision for how cures could become abundant, if we believe fast, systematic cure discovery is possible, and build the tools to make it happen.
www.gordian.bio/blog/cures-o...
@martinbjensen.bsky.social shared a long-term vision for how cures could become abundant, if we believe fast, systematic cure discovery is possible, and build the tools to make it happen.
www.gordian.bio/blog/cures-o...
May 16, 2025 at 9:10 PM
This news should instill urgency and remind us to ask ‘why not sooner?’.
@martinbjensen.bsky.social shared a long-term vision for how cures could become abundant, if we believe fast, systematic cure discovery is possible, and build the tools to make it happen.
www.gordian.bio/blog/cures-o...
@martinbjensen.bsky.social shared a long-term vision for how cures could become abundant, if we believe fast, systematic cure discovery is possible, and build the tools to make it happen.
www.gordian.bio/blog/cures-o...
Reposted by Martin Borch Jensen
1/ A long standing paradox in my mind (from always seeing immune "strength" or reactivity drawn as a spectrum from immunodeficiency to autoimmunity) was resolved this year at #AAI #Immunology2025. WHY do SO many people have both simultaneously? Each infection brings risk of developing autoimmunity!!
May 11, 2025 at 5:03 PM
1/ A long standing paradox in my mind (from always seeing immune "strength" or reactivity drawn as a spectrum from immunodeficiency to autoimmunity) was resolved this year at #AAI #Immunology2025. WHY do SO many people have both simultaneously? Each infection brings risk of developing autoimmunity!!
"Understanding an idea meant entangling it so thoroughly with all the other symbols in your mind that it changed the way you thought about everything."
@gregegansf.bsky.social
@gregegansf.bsky.social
April 30, 2025 at 2:25 PM
"Understanding an idea meant entangling it so thoroughly with all the other symbols in your mind that it changed the way you thought about everything."
@gregegansf.bsky.social
@gregegansf.bsky.social
Reposted by Martin Borch Jensen
I've started blogging on substack to provide a bit more depth. Rationale is provided in the first blog. I'm using some great artwork, but I've lost the source, so the great person who created FDA as Humpty Dumpty--please identify yourself!
substack.com/home/post/p-...
substack.com/home/post/p-...
Why Blog?
We are living in extraordinary times.
substack.com
April 23, 2025 at 4:54 PM
I've started blogging on substack to provide a bit more depth. Rationale is provided in the first blog. I'm using some great artwork, but I've lost the source, so the great person who created FDA as Humpty Dumpty--please identify yourself!
substack.com/home/post/p-...
substack.com/home/post/p-...
New Harvard website is amazing.
April 22, 2025 at 6:56 PM
New Harvard website is amazing.
@hanascientist.bsky.social and I wrote up some thoughts grappling with rising animosity and mistrust of scientists and their institutions. Would love feedback and responses. www.liebertpub.com/doi/full/10....
How Did Scientists Become the Enemy? | GEN Biotechnology
GEN Biotechnology
www.liebertpub.com
April 20, 2025 at 9:39 PM
@hanascientist.bsky.social and I wrote up some thoughts grappling with rising animosity and mistrust of scientists and their institutions. Would love feedback and responses. www.liebertpub.com/doi/full/10....
Reposted by Martin Borch Jensen
Kseniia Petrova, a Harvard scientist who fled Russia after protesting its invasion of Ukraine, has been captive to the hard-line immigration policies of the Trump administration for nearly eight weeks. She fears arrest if she is deported.
She Worked in a Harvard Lab to Reverse Aging, Until ICE Jailed Her
President Trump’s immigration crackdown ensnared Kseniia Petrova, a scientist who fled Russia after protesting its invasion of Ukraine. She fears arrest if she is deported there.
www.nytimes.com
April 11, 2025 at 3:59 PM
Kseniia Petrova, a Harvard scientist who fled Russia after protesting its invasion of Ukraine, has been captive to the hard-line immigration policies of the Trump administration for nearly eight weeks. She fears arrest if she is deported.
Appreciate everyone pushing science forward in these days.
Marton Meszaros wrote a great primer on what an #aging #biomarker needs to look like, and more importantly what the prerequisite datasets are.
Punchline: We may need to build them out, and should start now.
norn.group/writing/data...
Marton Meszaros wrote a great primer on what an #aging #biomarker needs to look like, and more importantly what the prerequisite datasets are.
Punchline: We may need to build them out, and should start now.
norn.group/writing/data...
Data Gaps that Bottleneck Aging Biomarker Discovery — Norn Group
What’s holding back aging biomarkers? Despite growing excitement, most aging biomarkers today remain clinically irrelevant. This piece dives into the real bottleneck: our data. It maps the missing da...
norn.group
April 9, 2025 at 5:42 PM
Appreciate everyone pushing science forward in these days.
Marton Meszaros wrote a great primer on what an #aging #biomarker needs to look like, and more importantly what the prerequisite datasets are.
Punchline: We may need to build them out, and should start now.
norn.group/writing/data...
Marton Meszaros wrote a great primer on what an #aging #biomarker needs to look like, and more importantly what the prerequisite datasets are.
Punchline: We may need to build them out, and should start now.
norn.group/writing/data...
Reposted by Martin Borch Jensen
Any scientists want to help with a science communication project? Will reach thousands on TikTok!
Details⬇️
Details⬇️
April 5, 2025 at 11:16 PM
Any scientists want to help with a science communication project? Will reach thousands on TikTok!
Details⬇️
Details⬇️
Reposted by Martin Borch Jensen
I've created a shareable document with a list of the HHS offices gutted today that I'll be updating as often as possible. Have something to add? Message marisakabas.04 on Signal or email MKwrites4000@proton.me
docs.google.com/document/d/1...
docs.google.com/document/d/1...
April 1, 2025 at 4:12 PM
I've created a shareable document with a list of the HHS offices gutted today that I'll be updating as often as possible. Have something to add? Message marisakabas.04 on Signal or email MKwrites4000@proton.me
docs.google.com/document/d/1...
docs.google.com/document/d/1...
Is it time to start splitting this governance experiment into a test and a control group? I mean, we have 50 states to work with, let's do some real economics and social science here.
April 3, 2025 at 3:21 AM
Is it time to start splitting this governance experiment into a test and a control group? I mean, we have 50 states to work with, let's do some real economics and social science here.
Aged well
On the one hand, this is so obviously bad that it seems like just some deliberately leaked bluster to try to get negotiation leverage, but on the other hand, the last few times I said that to myself they went ahead and did the obviously bad things anyway because it felt satisfying in the moment.
FU-U-U-U-U-U-U-U.... #EconSky
April 3, 2025 at 12:31 AM
Aged well
Reposted by Martin Borch Jensen
What are some mappings from deleterious cravings to the real need that satisfies the craving?
e. g. When you feel like eating candy, what you actually want is fruit. When you feel like playing videogames, what you actually want is progress and accomplishment. Etc.
e. g. When you feel like eating candy, what you actually want is fruit. When you feel like playing videogames, what you actually want is progress and accomplishment. Etc.
April 2, 2025 at 5:55 PM
What are some mappings from deleterious cravings to the real need that satisfies the craving?
e. g. When you feel like eating candy, what you actually want is fruit. When you feel like playing videogames, what you actually want is progress and accomplishment. Etc.
e. g. When you feel like eating candy, what you actually want is fruit. When you feel like playing videogames, what you actually want is progress and accomplishment. Etc.
Reposted by Martin Borch Jensen
I may be tired and a little hoarse, but as I said again and again on the Senate floor, this is a moment where we cannot afford to be silent, when we must speak up.
April 2, 2025 at 1:09 AM
I may be tired and a little hoarse, but as I said again and again on the Senate floor, this is a moment where we cannot afford to be silent, when we must speak up.
Reposted by Martin Borch Jensen
UPDATE: So excited to announce our newest program.
Using a 15-week cohort model, goal is help more scientists design the type of ambitious research programs that were critical to advancements such as the Internet or mRNA vaccines.
We plan to do multiple cohorts this year (info below).
Using a 15-week cohort model, goal is help more scientists design the type of ambitious research programs that were critical to advancements such as the Internet or mRNA vaccines.
We plan to do multiple cohorts this year (info below).
Today we launched the Big if True Science (BiTS) Accelerator—an accelerator to train scientists & researchers in designing and executing bold, field-changing coordinated research programs. Powered by our partnership with @aria-research.bsky.social, BiTS will launch its first cohort in Spring 2025.
March 31, 2025 at 10:48 PM
UPDATE: So excited to announce our newest program.
Using a 15-week cohort model, goal is help more scientists design the type of ambitious research programs that were critical to advancements such as the Internet or mRNA vaccines.
We plan to do multiple cohorts this year (info below).
Using a 15-week cohort model, goal is help more scientists design the type of ambitious research programs that were critical to advancements such as the Internet or mRNA vaccines.
We plan to do multiple cohorts this year (info below).