maorongxie.bsky.social
@maorongxie.bsky.social
Reposted
“Permanent Standard Time (not springing ahead in March) could prevent 300,000 cases of stroke per year and lower nationwide prevalence of obesity by 2.6 million.” #DitchDST
November 2, 2025 at 6:56 PM
Reposted
In Science, researchers report the observation of dendritic nanotubes in brain tissue from mice and humans. The discovery suggests that the current understanding of the brain’s organization may be incomplete, overlooking a hidden layer of connectivity. #SciencePerspective https://scim.ag/470Cdr4
Hidden networks in the brain
Dendritic nanotubes extend brain connectivity beyond synapses
scim.ag
October 13, 2025 at 3:20 PM
Reposted
“This is an immensely exciting development for the Huntington’s field.” https://scim.ag/4nnW62z
In a first, a gene therapy seems to slow Huntington disease
Small study suggests uniQure drug could be first successful treatment for devastating brain disorder
scim.ag
September 24, 2025 at 10:10 PM
Reposted
Why do cats insist on eating grass, when it only seems to make them throw up? Scientists have proposed many theories over the years, but the latest may be the one that sticks—literally. https://scim.ag/4ntn8VB
Gold-covered hairballs may reveal why cats eat grass
Spiky projections on plant matter may act like “drain snakes,” helping felines dislodge wads of fur
scim.ag
September 12, 2025 at 10:05 PM
Reposted
A new #ScienceReview looks at a different approach to drug discovery that may enable drugging of unconventional targets through stabilization of macromolecular complexes with molecules known as “LOCKTACs.”

Learn more: https://scim.ag/4lC2aCM
August 22, 2025 at 6:36 PM
Reposted
What I love about interferons is their simplicity ;-)
But seriously a great @cellcellpress.bsky.social new review of IFNs that are our 1st line of defense vs infections and have a critical role in many inflammatory an autoimmune diseases www.cell.com/cell/fulltex...
August 21, 2025 at 3:42 PM
Reposted
Cells are particularly good at solving mazes, according to a 2020 Science study that demonstrates how they are able to navigate long and complicated routes through the body using self-generated chemoattractant gradients.

Learn more: https://scim.ag/45HBSZM #ScienceMagArchives
August 21, 2025 at 4:08 PM
Reposted
Platelets sequester and harbor cell-free tumor DNA, which could enhance our ability to make early, microscopic diagnosis of cancer
@science.org

science.org/doi/10.1126/...
science.org/doi/10.1126/...
August 14, 2025 at 9:39 PM
Reposted
Would your #cellbio research benefit from you attending a #Microscopy or #BioimageAnalysis training course? For grants of up to £1,000, check out our Microscopy Training Grants with @focalplane.bsky.social
Next deadline: 5 September 2025
www.biologists.com/grants/jcs-f...
August 14, 2025 at 11:25 AM
Reposted
Metformin, the first line drug for Type 2 diabetes, has been used for 60 years without a clearcut mechanism of action. It turns out it's not just reducing glucose output from the liver. Metformin also works via the brain www.science.org/doi/10.1126/...
Low-dose metformin requires brain Rap1 for its antidiabetic action
Metformin lowers blood glucose by inhibiting Rap1 in ventromedial hypothalamic neurons that regulate glucose balance.
www.science.org
July 31, 2025 at 6:52 PM
Reposted
"On the one hand, we have a hypothesis underpinned by evidence, although imperfect, and on the other hand we have a hypothesis without evidence, although it might exist."

Our latest editorial in advance of our August issue

www.thelancet.com/journals/lan...

#IDSky #ClinMicro #ViroSky #SARS-CoV-2
July 29, 2025 at 11:35 AM
Reposted
🧠 New research from Institut Pasteur reveals how Long COVID works: SARS-CoV-2 persists in the brainstem for months after infection, disrupting dopamine production and neuronal activity.
#LongCOVID
Long COVID: SARS-CoV-2 persists in the brainstem in the long term and deregulates neuronal activity
Symptoms can persist in some SARS-CoV-2 patients several months after infection. Scientists at the Institut Pasteur have demonstrated in an animal model that SARS-CoV-2 infects the brain and persists ...
www.pasteur.fr
July 29, 2025 at 11:47 AM
Reposted
"The science of extreme longevity continues as an immense joke."
—The first man to “survive” past 110 actually died at 65.
—Blue zones are a myth
—Pervasive false claims about longevity and supercentenarians
Gift link www.nytimes.com/2025/01/20/o...
Opinion | The Science of Blue Zones and Extreme Longevity Is Deeply Flawed (Gift Article)
Some of the claims behind the longest-lived people are simply improbable.
www.nytimes.com
January 20, 2025 at 6:06 PM