Peruzzotti-Jametti et al. examine the remyelination potential of mouse- and human-derived directly induced neural stem cell (iNSC) grafts, and show that iNSCs can differentiate into mature oligodendrocytes and remyelinate axons in demyelinated lesions. tinyurl.com/3a2auah5

Excited to share our new paper in J Transl Med: translational-medicine.biomedcentral.com/articles/10....

ICV delivery of fetal-derived NSCs is safe and may slow disease in SOD1 ALS mice.
A small step in a bigger fight.
Grateful to all involved, and fitting timing during #ALSAwarenessMonth

A new chapter has begun for two of the world’s most popular preprint platforms, bioRxiv and medRxiv, with the launch of a non-profit organization that will manage them

https://go.nature.com/4iCVnHL

American science is under attack

Opinion piece by Dr Harold Varmus, Nobel Prize winner, former director of the #NIH and the #NCI 🧪

“Perhaps what’s most disheartening is what feels like the absence of widespread opposition to this unraveling”

www.nytimes.com/2025/02/14/o...

PhDone! 👨🏻‍🎓 Successfully defended my PhD thesis, “Stemming Neurodegeneration: The Therapeutic Potential of Neural Stem Cell Transplantation.”
Huge thanks to my mentors, colleagues, and everyone who supported me through this incredible journey. On to new scientific adventures! 🧠🔬

#Neuroscience #Onward

Let’s stop treating "leaving academia" as negative. Scientists train for academia, industry, or what suits them. Industry isn’t an alternative; it’s a choice. In fields like engineering, most PhDs go to industry, and no one calls it "leaving academia." We should train scientists for diverse paths.

More than 40% of postdoctoral researchers leave academia, according to a study of some 45,500 researchers’ careers

https://go.nature.com/3Ej9RxA

Il mio scienziato preferito (@scaltritilab.bsky.social) ha scritto un libro e voglio condividere perché più persone ne vengano a conoscenza. In questo periodo dove la scienza è sotto attacco con tanti guru che prosperano promettendo sogni, è bene difendere la ricerca scientifica. Quella vera! 🧪

Why do people who inherit the brain disease Huntington’s often only show symptoms well into adulthood, between 30 and 50 years of age?

https://go.nature.com/3DZaTPn

Nature’s survey of hiring in science has revealed a gulf between the expectations of people looking for jobs in science and those who hire

https://go.nature.com/3Wk76lP

We have a feeling you'll be interested in this one.

Nature is keen to find out how scientists are using Bluesky and whether it has become their go-to social-media platform. Take the survey! 🧪

Excited to see the new issue of @cp-immunity.bsky.social, with our cover 😍 RosaChiaraPaolicelli & Anne-ClaireCompagnion

In a collaborative study with the group of Philip Van Damme just published in BRAIN we identify a role for primary cilia in the pathogenesis of ALS! Big thanks to Mathias De Decker, Pavol ZELINA and all other co-authors! doi.org/10.1093/brai...

So excited to share our new @natureportfolio.bsky.social review on modeling human brain development using organoids! 🧠 Loved collaborating with the brilliant @lancasterlab.bsky.social , led by the incredible @marcellabirtele.bsky.social Check it out! 🔬 #Neuroscience #BrainOrganoids rdcu.be/d3llp

🧠 Excited to share our latest publication!

In this review, we explore and broadly discuss the current landscape of stem cell-based approaches for ALS, examining both preclinical models and clinical applications.

🔬 Check it out here: www.tandfonline.com/doi/full/10....

Couldn’t find a dedicated stem cell biology starter pack, so started one here: go.bsky.app/UTW4d7b

Feel free to repost/share and let me know if you would like to be added. #stemcell #pluripotency

Biomarkers are essential in the area of neurodegenerative disease. In a new review article, we discuss cargo changes (protein, RNA) in extracellular vesicles (EVs) in the context of three major neurodegenerative disorders (AD, ALS, PD). @umcutrecht.bsky.social rdcu.be/d2kBw