Brain
@brain1878.bsky.social
Brain has published landmark papers in clinical neurology and translational neuroscience since 1878.
Reposted by Brain
Have you read an outstanding paper published in Brain Communications during 2025? Take note of it for the Early Career Researcher Paper Prize! Nominations are Open! #ecr #paperprize #neuroscience
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January 4, 2026 at 4:01 PM
Have you read an outstanding paper published in Brain Communications during 2025? Take note of it for the Early Career Researcher Paper Prize! Nominations are Open! #ecr #paperprize #neuroscience
Link to form: buff.ly/8DWT8TV
Find out more at: buff.ly/5WfBuCR
Link to form: buff.ly/8DWT8TV
Find out more at: buff.ly/5WfBuCR
González-Velasco et al. show that somatic mutations in known ALS genes are enriched in the motor cortex of patients with sporadic ALS, particularly in excitatory neurons, and may contribute to disease initiation. tinyurl.com/24vx7shp
January 4, 2026 at 1:35 PM
González-Velasco et al. show that somatic mutations in known ALS genes are enriched in the motor cortex of patients with sporadic ALS, particularly in excitatory neurons, and may contribute to disease initiation. tinyurl.com/24vx7shp
Multiple studies have shown a mismatch between EEG parameters and subjective sleep quality. Hauglund & Nedergaard argue that nightly clearance of brain waste via the glymphatic system may be crucial for the restorative properties of sleep. tinyurl.com/2ju4cyc6
December 29, 2025 at 2:50 PM
Multiple studies have shown a mismatch between EEG parameters and subjective sleep quality. Hauglund & Nedergaard argue that nightly clearance of brain waste via the glymphatic system may be crucial for the restorative properties of sleep. tinyurl.com/2ju4cyc6
Defining neurological disease is less objective than often assumed. Simon Shorvon considers how confusion between symptoms and disease, shifting criteria, unstable classifications, and complex aetiology can undermine the medical model. tinyurl.com/5n8anfsc
December 14, 2025 at 5:45 PM
Defining neurological disease is less objective than often assumed. Simon Shorvon considers how confusion between symptoms and disease, shifting criteria, unstable classifications, and complex aetiology can undermine the medical model. tinyurl.com/5n8anfsc
Although new Alzheimer's disease therapies reduce amyloid plaques, they have not led to major clinical improvements. Pini et al. suggest that changes in brain connectivity may offer a more sensitive and biologically meaningful marker of disease modification. tinyurl.com/32975se3
December 12, 2025 at 3:25 PM
Although new Alzheimer's disease therapies reduce amyloid plaques, they have not led to major clinical improvements. Pini et al. suggest that changes in brain connectivity may offer a more sensitive and biologically meaningful marker of disease modification. tinyurl.com/32975se3
Thalamic highways as a bridge to neuromodulation
New scientific commentary by David Burdette, Bahram Sarvi Zargar & Paul Ferrari tinyurl.com/bdhh28dn
New scientific commentary by David Burdette, Bahram Sarvi Zargar & Paul Ferrari tinyurl.com/bdhh28dn
December 7, 2025 at 7:00 PM
Thalamic highways as a bridge to neuromodulation
New scientific commentary by David Burdette, Bahram Sarvi Zargar & Paul Ferrari tinyurl.com/bdhh28dn
New scientific commentary by David Burdette, Bahram Sarvi Zargar & Paul Ferrari tinyurl.com/bdhh28dn
White matter changes in Alzheimer's disease: contributor, consequence or co-pathology?
New scientific commentary by Julia Neitzel tinyurl.com/3x5ezsrc
New scientific commentary by Julia Neitzel tinyurl.com/3x5ezsrc
December 7, 2025 at 1:31 PM
White matter changes in Alzheimer's disease: contributor, consequence or co-pathology?
New scientific commentary by Julia Neitzel tinyurl.com/3x5ezsrc
New scientific commentary by Julia Neitzel tinyurl.com/3x5ezsrc
December's issue of Brain is now online! academic.oup.com/brain/issue/...
December 5, 2025 at 11:32 AM
December's issue of Brain is now online! academic.oup.com/brain/issue/...
One third of stroke survivors experience vision loss. Raffin et al. present a non-invasive brain stimulation technique targeting visual pathways and show that it improves perception and expands visual fields. tinyurl.com/yhppvzkv
December 2, 2025 at 6:02 PM
One third of stroke survivors experience vision loss. Raffin et al. present a non-invasive brain stimulation technique targeting visual pathways and show that it improves perception and expands visual fields. tinyurl.com/yhppvzkv
De Marchi et al. used FDG-PET and machine learning to examine neuropsychological and metabolic differences across the ALS-FTD spectrum, revealing distinct cognitive profiles and patterns of brain hypometabolism.
Profiling cognition and brain metabolism in amyotrophic lateral sclerosis and frontotemporal dementia
De Marchi et al. used [18F]FDG-PET and machine learning to examine neuropsychological and metabolic differences across the ALS-FTD spectrum. Their findings
tinyurl.com
December 1, 2025 at 4:38 PM
De Marchi et al. used FDG-PET and machine learning to examine neuropsychological and metabolic differences across the ALS-FTD spectrum, revealing distinct cognitive profiles and patterns of brain hypometabolism.
Koch et al. review motor skill learning and sensorimotor adaptation after stroke, highlighting ways in which lesion location, recovery stage, and individual differences affect learning, and offering recommendations for future research.
Motor learning after stroke: what we’ve learned and what lies ahead
Many stroke survivors experience motor impairments that limit their daily activities. Koch et al. review motor skill learning and sensorimotor adaptation a
tinyurl.com
November 29, 2025 at 10:49 AM
Koch et al. review motor skill learning and sensorimotor adaptation after stroke, highlighting ways in which lesion location, recovery stage, and individual differences affect learning, and offering recommendations for future research.
Weisman et al. critically examine the claim that pain can exist purely in the mind, without any physical trigger in the body, arguing instead that nociception is necessary – but not sufficient – for pain. tinyurl.com/yw88waba
November 28, 2025 at 10:23 PM
Weisman et al. critically examine the claim that pain can exist purely in the mind, without any physical trigger in the body, arguing instead that nociception is necessary – but not sufficient – for pain. tinyurl.com/yw88waba
Reposted by Brain
To commemorate the bicentenary of Jean-Martin Charcot's life. Without him Neurology would be a different speciality.
@uclqsion.bsky.social @brain1878.bsky.social @masudhusain.bsky.social
academic.oup.com/brain/articl...
@uclqsion.bsky.social @brain1878.bsky.social @masudhusain.bsky.social
academic.oup.com/brain/articl...
Charcot redux
Jean-Martin Charcot was born in Paris on 29 November 1825. To mark the bicentenary of his birth, the International Society for the History of the Neuroscie
academic.oup.com
November 19, 2025 at 9:41 AM
To commemorate the bicentenary of Jean-Martin Charcot's life. Without him Neurology would be a different speciality.
@uclqsion.bsky.social @brain1878.bsky.social @masudhusain.bsky.social
academic.oup.com/brain/articl...
@uclqsion.bsky.social @brain1878.bsky.social @masudhusain.bsky.social
academic.oup.com/brain/articl...
Cortical cerebral microinfarcts spark cognitive decline
New scientific commentary by Gemma Solé-Guardia, Anil Tuladhar & Frank-Erik de Leeuw: tinyurl.com/nhrr7fek
New scientific commentary by Gemma Solé-Guardia, Anil Tuladhar & Frank-Erik de Leeuw: tinyurl.com/nhrr7fek
November 17, 2025 at 9:42 PM
Cortical cerebral microinfarcts spark cognitive decline
New scientific commentary by Gemma Solé-Guardia, Anil Tuladhar & Frank-Erik de Leeuw: tinyurl.com/nhrr7fek
New scientific commentary by Gemma Solé-Guardia, Anil Tuladhar & Frank-Erik de Leeuw: tinyurl.com/nhrr7fek
Reposted by Brain
Are you familiar with immunoglobulin G’s pathophysiological role in fibromyalgia? Check out Israel et al.’s article in @brain1878.bsky.social, and Allan Basbaum’s comment on his view of this paper to find out! bit.ly/47B1fii #PRF
November 17, 2025 at 1:00 PM
Are you familiar with immunoglobulin G’s pathophysiological role in fibromyalgia? Check out Israel et al.’s article in @brain1878.bsky.social, and Allan Basbaum’s comment on his view of this paper to find out! bit.ly/47B1fii #PRF
Choo et al. show that damage to the medial temporal lobe – particularly the hippocampus – reduces the precision of memory for fine visual details, underscoring the role of this region in maintaining the fidelity of visual working memory representations. tinyurl.com/t2jxztz7
November 10, 2025 at 1:56 PM
Choo et al. show that damage to the medial temporal lobe – particularly the hippocampus – reduces the precision of memory for fine visual details, underscoring the role of this region in maintaining the fidelity of visual working memory representations. tinyurl.com/t2jxztz7
November's issue of Brain is now online! academic.oup.com/brain/issue/...
November 5, 2025 at 1:00 PM
November's issue of Brain is now online! academic.oup.com/brain/issue/...
Mukherjee et al. review how ageing affects remyelination in MS. While most studies suggest remyelination capacity decreases with age, findings are sometimes inconsistent, and remyelination remains possible at any age. tinyurl.com/c2ynpfrj
October 22, 2025 at 7:27 PM
Mukherjee et al. review how ageing affects remyelination in MS. While most studies suggest remyelination capacity decreases with age, findings are sometimes inconsistent, and remyelination remains possible at any age. tinyurl.com/c2ynpfrj
Togo et al. show strong electrophysiological links between the hippocampus and both the anterior and posterior thalamus, along with robust connections between thalamic subregions. tinyurl.com/5c6n23xj
October 22, 2025 at 7:26 PM
Togo et al. show strong electrophysiological links between the hippocampus and both the anterior and posterior thalamus, along with robust connections between thalamic subregions. tinyurl.com/5c6n23xj
Kollenburg et al. review the molecular mechanisms and regional activity patterns underlying headache disorders including migraine, cluster headache, and paroxysmal hemicrania. tinyurl.com/46aafjxu
October 13, 2025 at 7:56 PM
Kollenburg et al. review the molecular mechanisms and regional activity patterns underlying headache disorders including migraine, cluster headache, and paroxysmal hemicrania. tinyurl.com/46aafjxu
Reposted by Brain
The current environment is making it near impossible to run clinical trials in the UK.
One key issue discussed in @brain1878.bsky.social
is the duplication - or worse - of regulatory oversight at NHS hospitals & universities.
My views on how to change the system
academic.oup.com/brain/articl...
One key issue discussed in @brain1878.bsky.social
is the duplication - or worse - of regulatory oversight at NHS hospitals & universities.
My views on how to change the system
academic.oup.com/brain/articl...
October 6, 2025 at 6:07 AM
The current environment is making it near impossible to run clinical trials in the UK.
One key issue discussed in @brain1878.bsky.social
is the duplication - or worse - of regulatory oversight at NHS hospitals & universities.
My views on how to change the system
academic.oup.com/brain/articl...
One key issue discussed in @brain1878.bsky.social
is the duplication - or worse - of regulatory oversight at NHS hospitals & universities.
My views on how to change the system
academic.oup.com/brain/articl...
Pruckner et al. show that the structural effects of neurosurgery extend beyond the resected tissue into connected networks through transneuronal degeneration. They were able to reliably predict these changes from preoperative MRI. tinyurl.com/a6rxvbey
October 7, 2025 at 9:21 AM
Pruckner et al. show that the structural effects of neurosurgery extend beyond the resected tissue into connected networks through transneuronal degeneration. They were able to reliably predict these changes from preoperative MRI. tinyurl.com/a6rxvbey
New issue of Brain now online! tinyurl.com/mwxp6x24
October 4, 2025 at 7:19 PM
New issue of Brain now online! tinyurl.com/mwxp6x24
Avalos-Alais et al. present a high-resolution probabilistic map of bidirectional effective connectivity between the human lateral PFC and widespread cortical and subcortical regions, based on analysis of intracranial evoked potentials. tinyurl.com/br7htec9
October 3, 2025 at 8:35 AM
Avalos-Alais et al. present a high-resolution probabilistic map of bidirectional effective connectivity between the human lateral PFC and widespread cortical and subcortical regions, based on analysis of intracranial evoked potentials. tinyurl.com/br7htec9
Mongay-Ochoa et al. review advanced methods for mapping brain connections and identify common topographical patterns of pathology spread across different neurological disorders, including MS, AD and PD. tinyurl.com/3sz8ayup
September 19, 2025 at 8:33 PM
Mongay-Ochoa et al. review advanced methods for mapping brain connections and identify common topographical patterns of pathology spread across different neurological disorders, including MS, AD and PD. tinyurl.com/3sz8ayup