Nature Reviews Microbiology, Published online: 17 November 2025; doi:10.1038/s41579-025-01259-7In this Review, Kocher, Krause and Spyrou explore how ancient pathogen genomics is providing new perspectives on the history and evolution of infectious agents. They show how ancient DNA has revealed the aetiology and unfolding of historic outbreaks, pathogen evolutionary timescales, patterns of dissemination and functional evolution, and discuss existing limitations and perspectives of the field.

AbstractSummary. Endogenous viral elements (EVEs) offer valuable insights into virus and host evolution, but their detection remains computationally and bi

The panzootic of highly pathogenic H5N1 since 2021 was driven by around nine introductions into the Atlantic and Pacific flyways, followed by rapid dissemination through wild migratory birds, primaril...

The old one failed to cope with Covid and may even have caused it.

A search for analogues of the human SAMD9/9L antiviral genes identifies convergent evolution of this gene family in the bacterial and animal kingdoms, with species-specific and recent genomic signatur...

For over a century, evolutionary biologists have been motivated to understand the mechanisms through which organisms adapt to their environments. Coloration and pigmentation are remarkably variable wi...

As part of the HEAS Seminar Series in Ancient Genomics Maria C Avila-Arcos from National Autonomous University of Mexico will give a talk on Paleogenomic evidence of patogen introductions to Mexico fo...

Pandemic preparedness is critical as we face potential threats of infectious diseases. Systems virology and collaborative/responsive science are key infrastructures that facilitated scientific advance...

In this study, the authors analysed a large genomic dataset to trace how jumping genes shaped the global spread of a major wheat pathogen and reveal bursts of activity over decades that drove adaptati...

Despite its extraordinary genetic diversity, Latin America remains largely absent from global genomic studies. Dr Patricia Abrão Possik discusses efforts to boost regional research capacity and insights from her work on acral melanoma.

Submitting an Application Current Fellows 2025 Cohort Additional Information Humberger Toggle Menu Interested in applying for a Postdoctoral Research Fellowship? Eligibility The program seeks applican...

The short documentary “Rovina’s Choice” tells the story of what goes when aid goes.

Online platforms for sharing virus sequences are in disarray. The World Health Organization has a chance to build something new

A comprehensive single-nucleus RNA-seq atlas of >367,000 nuclei from male and female Aedes aegypti mosquitoes reveals sexual dimorphism in sensory systems and brain cell types and widespread co-expres...

Pathoplexus is a new platform for sharing pathogen sequence data, launched in August 2024 [1], with the primary aim of making sharing and accessing pathogen genomic data easier, faster, and more effic...