Leigh Knodler
@leighknodler.bsky.social
Australian first | Scientist second | Associate Professor at The University of Vermont | FirstGen | Lover of germs, especially Salmonella and their type III secretion systems
Reposted by Leigh Knodler
Amazon is helping fund a $300 million build of a ballroom for the White House.
Independent bookstores are donating to food banks and organizations that help with food insecurity.
They are not the same.
Independent bookstores are donating to food banks and organizations that help with food insecurity.
They are not the same.
October 30, 2025 at 4:01 PM
Amazon is helping fund a $300 million build of a ballroom for the White House.
Independent bookstores are donating to food banks and organizations that help with food insecurity.
They are not the same.
Independent bookstores are donating to food banks and organizations that help with food insecurity.
They are not the same.
Reposted by Leigh Knodler
UMN's Department of Microbiology and Immunology is hiring! Come be our colleague in the Twin Cities! Searches are open for Virology and Fungal Biology (links below).
Virology: hr.myu.umn.edu/jobs/ext/365...
Fungal Biology/Medical Mycology: hr.myu.umn.edu/jobs/ext/365...
Virology: hr.myu.umn.edu/jobs/ext/365...
Fungal Biology/Medical Mycology: hr.myu.umn.edu/jobs/ext/365...
October 26, 2025 at 7:40 PM
UMN's Department of Microbiology and Immunology is hiring! Come be our colleague in the Twin Cities! Searches are open for Virology and Fungal Biology (links below).
Virology: hr.myu.umn.edu/jobs/ext/365...
Fungal Biology/Medical Mycology: hr.myu.umn.edu/jobs/ext/365...
Virology: hr.myu.umn.edu/jobs/ext/365...
Fungal Biology/Medical Mycology: hr.myu.umn.edu/jobs/ext/365...
Reposted by Leigh Knodler
Coenzyme A depletion causes antibiotic tolerance in Pseudomonas aeruginosa https://www.biorxiv.org/content/10.1101/2025.10.24.684135v1
October 25, 2025 at 5:18 AM
Coenzyme A depletion causes antibiotic tolerance in Pseudomonas aeruginosa https://www.biorxiv.org/content/10.1101/2025.10.24.684135v1
Reposted by Leigh Knodler
Come join us in Knoxville!
The Dept. of Microbiology 🧫🦠 at the University of Tennessee is hiring 2 Assistant Professors (tenure track, 9-month appt.).
Microbial Drivers of Chronic Disease: apply.interfolio.com/173153Quantitative Microbe-Plant-Environment Interactions: apply.interfolio.com/173345
The Dept. of Microbiology 🧫🦠 at the University of Tennessee is hiring 2 Assistant Professors (tenure track, 9-month appt.).
Microbial Drivers of Chronic Disease: apply.interfolio.com/173153Quantitative Microbe-Plant-Environment Interactions: apply.interfolio.com/173345
October 24, 2025 at 12:18 PM
Come join us in Knoxville!
The Dept. of Microbiology 🧫🦠 at the University of Tennessee is hiring 2 Assistant Professors (tenure track, 9-month appt.).
Microbial Drivers of Chronic Disease: apply.interfolio.com/173153Quantitative Microbe-Plant-Environment Interactions: apply.interfolio.com/173345
The Dept. of Microbiology 🧫🦠 at the University of Tennessee is hiring 2 Assistant Professors (tenure track, 9-month appt.).
Microbial Drivers of Chronic Disease: apply.interfolio.com/173153Quantitative Microbe-Plant-Environment Interactions: apply.interfolio.com/173345
Reposted by Leigh Knodler
The unique lipopolysaccharide composition of Salmonella Typhimurium ST313 dampens pyroptosis and inflammasome activation and suppresses host cell death https://www.biorxiv.org/content/10.1101/2025.09.29.679141v1
September 30, 2025 at 3:18 AM
The unique lipopolysaccharide composition of Salmonella Typhimurium ST313 dampens pyroptosis and inflammasome activation and suppresses host cell death https://www.biorxiv.org/content/10.1101/2025.09.29.679141v1
Reposted by Leigh Knodler
I'm not sure you can get more marie antoinette than taking away food stamps before thanksgiving while you build a gold and marble dance hall so the other crooks can bring bribe you over a badly-cooked (argentinian) steak
October 22, 2025 at 11:53 AM
I'm not sure you can get more marie antoinette than taking away food stamps before thanksgiving while you build a gold and marble dance hall so the other crooks can bring bribe you over a badly-cooked (argentinian) steak
Reposted by Leigh Knodler
Check out our new publication, a collaboration with Giovanni Luchetti and Vishva Dixit @ Genentech.
We show that the E.coli effector NleL inhibits intestinal epithelial cell extrusion after #inflammasome activation via degrading the kinases ROCK1 and 2!!
www.nature.com/articles/s41...
Explainer 1/8
We show that the E.coli effector NleL inhibits intestinal epithelial cell extrusion after #inflammasome activation via degrading the kinases ROCK1 and 2!!
www.nature.com/articles/s41...
Explainer 1/8
Enteropathogenic bacteria evade ROCK-driven epithelial cell extrusion - Nature
The bacterial ubiquitin ligase NleL evades host defence mechanisms both by inhibiting pyroptosis and by preventing infected intestinal epithelial cells from being extruded into the lumen and expelled ...
www.nature.com
October 22, 2025 at 3:47 PM
Check out our new publication, a collaboration with Giovanni Luchetti and Vishva Dixit @ Genentech.
We show that the E.coli effector NleL inhibits intestinal epithelial cell extrusion after #inflammasome activation via degrading the kinases ROCK1 and 2!!
www.nature.com/articles/s41...
Explainer 1/8
We show that the E.coli effector NleL inhibits intestinal epithelial cell extrusion after #inflammasome activation via degrading the kinases ROCK1 and 2!!
www.nature.com/articles/s41...
Explainer 1/8
Reposted by Leigh Knodler
Open position to work on Type IX secretion (#T9SS) in our lab, in collaboration withe the group of Eric Reynolds at the Dental School of the University of Melbourne. Please spread the word, and forward to anyone potentially interested ! Apply here:
emploi.cnrs.fr/Offres/Docto...
emploi.cnrs.fr/Offres/Docto...
Portail Emploi CNRS - Offre d'emploi - Thèse en Microbiologie-Biochimie (H/F)
emploi.cnrs.fr
October 9, 2025 at 12:18 PM
Open position to work on Type IX secretion (#T9SS) in our lab, in collaboration withe the group of Eric Reynolds at the Dental School of the University of Melbourne. Please spread the word, and forward to anyone potentially interested ! Apply here:
emploi.cnrs.fr/Offres/Docto...
emploi.cnrs.fr/Offres/Docto...
Reposted by Leigh Knodler
The mystery of medical diagnosis!
October 3, 2025 at 6:25 PM
The mystery of medical diagnosis!
Reposted by Leigh Knodler
Job alert ‼️ UChicago Micro is hiring! Open to tenured/tenure track faculty at all levels in any area of microbiology. Come join our amazing and growing department. apply.interfolio.com/174404
October 4, 2025 at 6:44 PM
Job alert ‼️ UChicago Micro is hiring! Open to tenured/tenure track faculty at all levels in any area of microbiology. Come join our amazing and growing department. apply.interfolio.com/174404
"We became inconvenient".
NIH whistleblower details clash over childhood vaccines with Trump administration: "We became inconvenient"
A former NIH official says she was removed after clashes over vaccines, accusing RFK Jr. and his deputies of posing "a substantial and specific danger to public health and safety."
www.cbsnews.com
September 9, 2025 at 12:01 PM
"We became inconvenient".
Reposted by Leigh Knodler
I am delighted to announce that the UW Department of Biochemistry has opened searches for TWO tenure-track positions.
Descriptions and links in the following two posts.
Descriptions and links in the following two posts.
August 28, 2025 at 8:47 PM
I am delighted to announce that the UW Department of Biochemistry has opened searches for TWO tenure-track positions.
Descriptions and links in the following two posts.
Descriptions and links in the following two posts.
Reposted by Leigh Knodler
Three postdoc positions are now open for applications! Live and work on Kaurna land (Adelaide) in sunny South Australia. We have beach views, wineries, kangaroos, and koalas.
Develop new synthetic biology to engineer and understand #phage, and computational tools for #phage and #microbiome analysis
Develop new synthetic biology to engineer and understand #phage, and computational tools for #phage and #microbiome analysis
August 29, 2025 at 9:41 AM
Three postdoc positions are now open for applications! Live and work on Kaurna land (Adelaide) in sunny South Australia. We have beach views, wineries, kangaroos, and koalas.
Develop new synthetic biology to engineer and understand #phage, and computational tools for #phage and #microbiome analysis
Develop new synthetic biology to engineer and understand #phage, and computational tools for #phage and #microbiome analysis
Reposted by Leigh Knodler
Unfortunate truth is, U.S. academics are not going to find jobs overseas. Some of the biggest name glam faculty will be poached, but for most, the ride is just going to end.
This isn't to say other countries won't take the lead in research, etc. They'll just do it mostly with their own citizens.
This isn't to say other countries won't take the lead in research, etc. They'll just do it mostly with their own citizens.
Australian universities to cut about 2,400 jobs and hundreds of courses as sector blames ‘confused’ government policies
Vice-chancellors say they’ve been forced to restructure but critics point finger at ‘unaccountable’ university management
www.theguardian.com
August 24, 2025 at 4:39 PM
Unfortunate truth is, U.S. academics are not going to find jobs overseas. Some of the biggest name glam faculty will be poached, but for most, the ride is just going to end.
This isn't to say other countries won't take the lead in research, etc. They'll just do it mostly with their own citizens.
This isn't to say other countries won't take the lead in research, etc. They'll just do it mostly with their own citizens.
Reposted by Leigh Knodler
We are hiring! The Dept of Microbiology and Molecular Genetics is looking for faculty at the Assistant or Associate professor level (tenure track). Please consider joining our vibrant microbiology and immunology community at the University of Pittsburgh School of medicine
August 20, 2025 at 7:41 PM
We are hiring! The Dept of Microbiology and Molecular Genetics is looking for faculty at the Assistant or Associate professor level (tenure track). Please consider joining our vibrant microbiology and immunology community at the University of Pittsburgh School of medicine
Reposted by Leigh Knodler
Are the mRNA vaccines incredible? YES!
Are the mRNA vaccines perfect? No.
Have the mRNA vaccines saved millions of lives? YES!
Can we make the mRNA vaccines even better? YES!
Can we use mRNA vaccine technology to prevent and treat many other diseases? YES!
Fund mRNA research!
Are the mRNA vaccines perfect? No.
Have the mRNA vaccines saved millions of lives? YES!
Can we make the mRNA vaccines even better? YES!
Can we use mRNA vaccine technology to prevent and treat many other diseases? YES!
Fund mRNA research!
August 19, 2025 at 2:54 AM
Are the mRNA vaccines incredible? YES!
Are the mRNA vaccines perfect? No.
Have the mRNA vaccines saved millions of lives? YES!
Can we make the mRNA vaccines even better? YES!
Can we use mRNA vaccine technology to prevent and treat many other diseases? YES!
Fund mRNA research!
Are the mRNA vaccines perfect? No.
Have the mRNA vaccines saved millions of lives? YES!
Can we make the mRNA vaccines even better? YES!
Can we use mRNA vaccine technology to prevent and treat many other diseases? YES!
Fund mRNA research!
Reposted by Leigh Knodler
📢 Tell your friends and colleagues about JEM’s Early Career Travel Award! ✈️🧳 We're providing support for #gradstudents and early-career #postdoc researchers to attend #Cytokines2025, this November in Seattle! Apply by Sept. 26 👉 rupress.org/jem/pages/ea...
August 19, 2025 at 2:15 PM
📢 Tell your friends and colleagues about JEM’s Early Career Travel Award! ✈️🧳 We're providing support for #gradstudents and early-career #postdoc researchers to attend #Cytokines2025, this November in Seattle! Apply by Sept. 26 👉 rupress.org/jem/pages/ea...
Reposted by Leigh Knodler
Faculty search announcement 2025: Tenure-Track Assistant Professor in Microbiology at UT Southwestern. We seek candidates working in microbial pathogenesis (some preference may be given to bacterial pathogens). Come join our community! (1/5) www.utsouthwestern.edu/departments/...
August 18, 2025 at 2:31 PM
Faculty search announcement 2025: Tenure-Track Assistant Professor in Microbiology at UT Southwestern. We seek candidates working in microbial pathogenesis (some preference may be given to bacterial pathogens). Come join our community! (1/5) www.utsouthwestern.edu/departments/...
Reposted by Leigh Knodler
“Grant review by political appointees will further impede the work of the scientific community to provide solutions and fight public health threats. With strong and responsible oversight, we need to harness—not suppress—all perspectives and approaches in the effort to solve these problems.”
August 8, 2025 at 8:08 PM
“Grant review by political appointees will further impede the work of the scientific community to provide solutions and fight public health threats. With strong and responsible oversight, we need to harness—not suppress—all perspectives and approaches in the effort to solve these problems.”
Reposted by Leigh Knodler
The White House is taking new steps to undermine every international student at our universities.
It has approved a new rule restricting student visas to 4 years max. That's not long enough for PhD students, or about half of undergrads, to finish their degree.
Likely to enter force within days.
It has approved a new rule restricting student visas to 4 years max. That's not long enough for PhD students, or about half of undergrads, to finish their degree.
Likely to enter force within days.
August 8, 2025 at 11:20 AM
The White House is taking new steps to undermine every international student at our universities.
It has approved a new rule restricting student visas to 4 years max. That's not long enough for PhD students, or about half of undergrads, to finish their degree.
Likely to enter force within days.
It has approved a new rule restricting student visas to 4 years max. That's not long enough for PhD students, or about half of undergrads, to finish their degree.
Likely to enter force within days.
That concludes GRC Salmonella 2025. What a fantastic meeting it was - topnotch science, great discussions and a wonderful spirit. I am proud to be part of this amazing scientific community.
August 8, 2025 at 12:58 PM
That concludes GRC Salmonella 2025. What a fantastic meeting it was - topnotch science, great discussions and a wonderful spirit. I am proud to be part of this amazing scientific community.
It’s happening!!!
August 3, 2025 at 9:47 PM
It’s happening!!!
Reposted by Leigh Knodler
Ready to lead pioneering research that bridges systems-level investigations of biological systems to molecular mechanism? The EMBL Molecular Systems Biology Unit in Heidelberg is hiring a Group Leader!
Group Leader – Molecular Systems Biology Unit
Are you ready to lead groundbreaking research in Molecular Systems Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group, addressing original biological ...
embl.wd103.myworkdayjobs.com
July 30, 2025 at 3:15 PM
Ready to lead pioneering research that bridges systems-level investigations of biological systems to molecular mechanism? The EMBL Molecular Systems Biology Unit in Heidelberg is hiring a Group Leader!
Reposted by Leigh Knodler
🧪BREAKING: NIH has laid out 5 options for funding publications costs on grants (yes, FIVE!). This is hugely impactful.
Make your opinions known by September 15, fellow scientists.
🧪
grants.nih.gov/grants/guide...
Make your opinions known by September 15, fellow scientists.
🧪
grants.nih.gov/grants/guide...
NOT-OD-25-138: Request for Information on Maximizing Research Funds by Limiting Allowable Publishing Costs
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Request for Information on Maximizing Research Funds by Limiting Allowable Publishing Costs NOT-OD-25-138. NIH
grants.nih.gov
July 30, 2025 at 6:30 PM
🧪BREAKING: NIH has laid out 5 options for funding publications costs on grants (yes, FIVE!). This is hugely impactful.
Make your opinions known by September 15, fellow scientists.
🧪
grants.nih.gov/grants/guide...
Make your opinions known by September 15, fellow scientists.
🧪
grants.nih.gov/grants/guide...