Laura Stephen
@laurastephen.bsky.social
Reposted by Laura Stephen
A short preprint describing our adoption of more consistent and precise use of terminology related to reproducibility, robustness, replicability, repeatability, and credibility.
osf.io/preprints/me...
osf.io/preprints/me...
December 3, 2025 at 6:51 PM
A short preprint describing our adoption of more consistent and precise use of terminology related to reproducibility, robustness, replicability, repeatability, and credibility.
osf.io/preprints/me...
osf.io/preprints/me...
Reposted by Laura Stephen
Your health data helps researchers improve understanding of health conditions and develop better ways to diagnose and treat them. We also believe it is our responsibility to make sure public are aware of their right to opt out of research within the SDE, should they wish to do so.
December 3, 2025 at 5:05 PM
Your health data helps researchers improve understanding of health conditions and develop better ways to diagnose and treat them. We also believe it is our responsibility to make sure public are aware of their right to opt out of research within the SDE, should they wish to do so.
Reposted by Laura Stephen
the degree to which Labour have limboed under my lowest expectations for them is remarkable.
what the fuck
November 25, 2025 at 7:48 PM
the degree to which Labour have limboed under my lowest expectations for them is remarkable.
Reposted by Laura Stephen
Her parents bought the house in the 1960s for £21K and now it's worth £1.2 million
It is insane that some people think you should just be able to keep all of that - if you've made a big profit, it is fair you should get taxed on that
It is insane that some people think you should just be able to keep all of that - if you've made a big profit, it is fair you should get taxed on that
I don't think this was actually deliberately published as ragebait, but the entitlement contained within is remarkable and a classic example of the sort of sentiment governments sometimes just have to face down inews.co.uk/inews-lifest...?
November 24, 2025 at 11:13 AM
Reposted by Laura Stephen
The framing of this story as "£148k tax bill" rather than "woman inherits a £1.2 million pound house and *only* has to pay 10% tax" is because the news media want people to be upset about tax, rather than upset at the rich paying very little of it.
I don't think this was actually deliberately published as ragebait, but the entitlement contained within is remarkable and a classic example of the sort of sentiment governments sometimes just have to face down inews.co.uk/inews-lifest...?
We were hit with a £148k inheritance tax bill when mum died at 97 - it's disgusting
Jill Lemon has labelled inheritance tax as 'cruel', 'horrible' and 'unfair'
inews.co.uk
November 24, 2025 at 8:53 AM
The framing of this story as "£148k tax bill" rather than "woman inherits a £1.2 million pound house and *only* has to pay 10% tax" is because the news media want people to be upset about tax, rather than upset at the rich paying very little of it.
Reposted by Laura Stephen
Curious to know what a poster entitled 'DNA in The Fast Lane' is about?
Come along to our FREE open event on paediatric research 20th Nov & find out!
Great posters to view, researcher talks & refreshments..did we mention this event is FREE?? bit.ly/47EIvhV
@cuh.nhs.uk @cam.ac.uk @cph.bsky.social
Come along to our FREE open event on paediatric research 20th Nov & find out!
Great posters to view, researcher talks & refreshments..did we mention this event is FREE?? bit.ly/47EIvhV
@cuh.nhs.uk @cam.ac.uk @cph.bsky.social
November 14, 2025 at 12:52 PM
Curious to know what a poster entitled 'DNA in The Fast Lane' is about?
Come along to our FREE open event on paediatric research 20th Nov & find out!
Great posters to view, researcher talks & refreshments..did we mention this event is FREE?? bit.ly/47EIvhV
@cuh.nhs.uk @cam.ac.uk @cph.bsky.social
Come along to our FREE open event on paediatric research 20th Nov & find out!
Great posters to view, researcher talks & refreshments..did we mention this event is FREE?? bit.ly/47EIvhV
@cuh.nhs.uk @cam.ac.uk @cph.bsky.social
Reposted by Laura Stephen
Come and join us here in Cambridge! Applications open for a new faculty position, for a researcher in computational and/or theoretical biology, based jointly in Genetics and Mathematics. Happy to answer questions about research, teaching and working here.
www.cam.ac.uk/jobs/faculty...
www.cam.ac.uk/jobs/faculty...
Faculty Position in Computational Biology
Applications are invited for an Assistant/ Associate Professorship in Computational Biology to commence on 1 April 2026 or shortly thereafter. This is a joint post between the Department of Applied
www.cam.ac.uk
November 11, 2025 at 9:05 PM
Come and join us here in Cambridge! Applications open for a new faculty position, for a researcher in computational and/or theoretical biology, based jointly in Genetics and Mathematics. Happy to answer questions about research, teaching and working here.
www.cam.ac.uk/jobs/faculty...
www.cam.ac.uk/jobs/faculty...
Reposted by Laura Stephen
Understanding Patient Data recently commissioned research exploring how Integrated Care Systems across England are currently using and sharing patient data and how this data could be better harnessed to improve health services for local communities. understandingpatientdata.org.uk/ics-data-res...
Research into the use of data by Integrated Care Systems (ICSs)
Understanding Patient Data supports conversations with the public, patients and healthcare professionals about the uses of health information for care and research.
understandingpatientdata.org.uk
November 6, 2025 at 9:21 AM
Understanding Patient Data recently commissioned research exploring how Integrated Care Systems across England are currently using and sharing patient data and how this data could be better harnessed to improve health services for local communities. understandingpatientdata.org.uk/ics-data-res...
Reposted by Laura Stephen
Know your rights when voting today.
November 4, 2025 at 6:45 PM
Know your rights when voting today.
Reposted by Laura Stephen
Check out our new preprint on the evolution of enhancer loss. Turns out there are 50 ways to lose a function. We found four of them.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Distinct mechanisms decommission redundant enhancers to facilitate phenotypic evolution
The evolutionary loss of morphological traits is often driven by changes in gene regulation. Many developmental genes are controlled by multiple, redundant enhancers, raising the question of how robus...
www.biorxiv.org
October 28, 2025 at 8:06 PM
Check out our new preprint on the evolution of enhancer loss. Turns out there are 50 ways to lose a function. We found four of them.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Laura Stephen
It’s cool how they run with this story and headline with just a tiny bit buried deep in the article:
“All of Palisade’s scenarios were run in contrived test environments that critics say are far-removed from real-use cases.”
“All of Palisade’s scenarios were run in contrived test environments that critics say are far-removed from real-use cases.”
AI models may be developing their own ‘survival drive’, researchers say
Like 2001: A Space Odyssey’s HAL 9000, some AIs seem to resist being turned off and will even sabotage shutdown
www.theguardian.com
October 25, 2025 at 1:42 PM
It’s cool how they run with this story and headline with just a tiny bit buried deep in the article:
“All of Palisade’s scenarios were run in contrived test environments that critics say are far-removed from real-use cases.”
“All of Palisade’s scenarios were run in contrived test environments that critics say are far-removed from real-use cases.”
Reposted by Laura Stephen
I regularly get derailed when someone tries to benchmark clustering methods, trying the find the "best" one or the one that agrees with "ground truth".
Which clustering of the below animals is the best or the true one? By row, or by column?
Which clustering of the below animals is the best or the true one? By row, or by column?
October 16, 2025 at 9:44 AM
I regularly get derailed when someone tries to benchmark clustering methods, trying the find the "best" one or the one that agrees with "ground truth".
Which clustering of the below animals is the best or the true one? By row, or by column?
Which clustering of the below animals is the best or the true one? By row, or by column?
Reposted by Laura Stephen
Awesome work by @zornitza.bsky.social and collaborators showing the immediate value of WGS for newborn screening in a cohort of 1,000 Australian babies. Now we need larger, more diverse cohorts to show this approach can achieve population scale!
🤗 Out now @naturemedicine.bsky.social results of our genomic NBS study BabyScreen+ 👶🧬
👉 www.nature.com/articles/s41...
1,000 babies
WGS using existing cards
600+ conditions
13 day TAT
16 diagnoses (vs 1 in std NBS)
High clinical impact
High parental acceptability
👉 www.nature.com/articles/s41...
1,000 babies
WGS using existing cards
600+ conditions
13 day TAT
16 diagnoses (vs 1 in std NBS)
High clinical impact
High parental acceptability
October 14, 2025 at 9:54 PM
Awesome work by @zornitza.bsky.social and collaborators showing the immediate value of WGS for newborn screening in a cohort of 1,000 Australian babies. Now we need larger, more diverse cohorts to show this approach can achieve population scale!
Reposted by Laura Stephen
15 years in the making, we confirmed that mitochondria - the powerhouse of the cell - have an unusual localization in patients who experience psychosis (including schizophrenia and bipolar disorders). You’ll never guess what kind of patient cells we used to make this discovery… 🧵
October 10, 2025 at 4:47 PM
15 years in the making, we confirmed that mitochondria - the powerhouse of the cell - have an unusual localization in patients who experience psychosis (including schizophrenia and bipolar disorders). You’ll never guess what kind of patient cells we used to make this discovery… 🧵
Reposted by Laura Stephen
A reminder that the PhD program for EMBL is open for winter recruitment round. If you want to understand life at a molecular level and have a quantitative science (you don't have to have done biology - we love our mathematicians/physcists/chemists!) apply www.embl.org/about/info/e...
Application – EMBL International PhD Programme
www.embl.org
October 9, 2025 at 4:51 AM
A reminder that the PhD program for EMBL is open for winter recruitment round. If you want to understand life at a molecular level and have a quantitative science (you don't have to have done biology - we love our mathematicians/physcists/chemists!) apply www.embl.org/about/info/e...
Reposted by Laura Stephen
We’re looking for people to join our Data Access Committee- a unique opportunity to help shape the ethical use of NHS data for research. Check out the role description and apply here!
#DAC #EastOfEngland #HealthResearch #PoweredByData
#DAC #EastOfEngland #HealthResearch #PoweredByData
September 29, 2025 at 8:38 AM
We’re looking for people to join our Data Access Committee- a unique opportunity to help shape the ethical use of NHS data for research. Check out the role description and apply here!
#DAC #EastOfEngland #HealthResearch #PoweredByData
#DAC #EastOfEngland #HealthResearch #PoweredByData
Reposted by Laura Stephen
“But really, this time is different!”
*The AI boom = one of the costliest building sprees in world history
* Past 3 years' commitments are greater than the cost of building the U.S. interstate highway system
* Consumers must spend $800 billion on AI within a few years, to justify investment from 2023-24
www.wsj.com/tech/ai/ai-b...
* Past 3 years' commitments are greater than the cost of building the U.S. interstate highway system
* Consumers must spend $800 billion on AI within a few years, to justify investment from 2023-24
www.wsj.com/tech/ai/ai-b...
September 26, 2025 at 1:58 PM
“But really, this time is different!”
Reposted by Laura Stephen
I get that the news cycle is packed right now, but I just heard from a colleague at the Smithsonian that this is fully a GIANT SQUID BEING EATEN BY A SPERM WHALE and it’s possibly the first ever confirmed video according to a friend at NOAA
10 YEAR OLD ME IS LOSING HER MIND (a thread 🧵)
10 YEAR OLD ME IS LOSING HER MIND (a thread 🧵)
September 24, 2025 at 8:30 PM
I get that the news cycle is packed right now, but I just heard from a colleague at the Smithsonian that this is fully a GIANT SQUID BEING EATEN BY A SPERM WHALE and it’s possibly the first ever confirmed video according to a friend at NOAA
10 YEAR OLD ME IS LOSING HER MIND (a thread 🧵)
10 YEAR OLD ME IS LOSING HER MIND (a thread 🧵)
Reposted by Laura Stephen
Today is #WorldPatientSafetyDay At Cambridge BRC patient safety is at the heart of all that we do. Learn about the research taking place bit.ly/3VotyJR & how our PPI panel's contributions help make research more relevant & likely to succeed in the real world bit.ly/46lM3ne
@cuh.nhs.uk @cam.ac.uk
@cuh.nhs.uk @cam.ac.uk
September 17, 2025 at 3:47 PM
Today is #WorldPatientSafetyDay At Cambridge BRC patient safety is at the heart of all that we do. Learn about the research taking place bit.ly/3VotyJR & how our PPI panel's contributions help make research more relevant & likely to succeed in the real world bit.ly/46lM3ne
@cuh.nhs.uk @cam.ac.uk
@cuh.nhs.uk @cam.ac.uk
Reposted by Laura Stephen
Who knew that by the time Owen Cooper was collecting his awards we'd have completely patched "we must act now on the corrosive online influences on young men" in favour of "I love my flags too you know" and "Charlie Kirk was a harmless free speech activist"
Owen Cooper won the #Emmy award for best supporting actor in a limited series for "Adolescence." At 15, he is the youngest winner in the category in over 40 years.
Follow live updates: bit.ly/4glRF5r
Follow live updates: bit.ly/4glRF5r
September 15, 2025 at 10:31 AM
Who knew that by the time Owen Cooper was collecting his awards we'd have completely patched "we must act now on the corrosive online influences on young men" in favour of "I love my flags too you know" and "Charlie Kirk was a harmless free speech activist"
Reposted by Laura Stephen
Yesterday's piece from @jamellebouie.net is the only high-profile piece I've seen that specifically discusses the watchlist, its effect on academics, and its effect on public attitudes toward academia as a whole. (gift link)
www.nytimes.com/2025/09/13/o...
www.nytimes.com/2025/09/13/o...
September 14, 2025 at 3:10 PM
Yesterday's piece from @jamellebouie.net is the only high-profile piece I've seen that specifically discusses the watchlist, its effect on academics, and its effect on public attitudes toward academia as a whole. (gift link)
www.nytimes.com/2025/09/13/o...
www.nytimes.com/2025/09/13/o...
Reposted by Laura Stephen
Are you an AI expert who wants to stay in academia and change the world by understanding the most complex things we know - living organisms? Want to lead your own group, based in Heidelberg DE, working language English? @embl.org is hiring in AI embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Group Leader – AI in Biology
Are you ready to lead groundbreaking research in AI for Biology? Join us at EMBL! We are seeking a visionary scientist to establish their own independent research group bridging innovations in machine...
embl.wd103.myworkdayjobs.com
September 8, 2025 at 11:43 AM
Are you an AI expert who wants to stay in academia and change the world by understanding the most complex things we know - living organisms? Want to lead your own group, based in Heidelberg DE, working language English? @embl.org is hiring in AI embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Reposted by Laura Stephen
Reposted by Laura Stephen
"Conservatism consists of exactly one proposition, to wit: There must be in-groups whom the law protects but does not bind, alongside out-groups whom the law binds but does not protect."
New pet peeve: conservative women’s mantra - “rules for thee, not for me.”
Women shouldn’t hold office, says GOP woman now running for office
“I don’t know if I would vote for any female,” said state senate hopeful Mylie Biggs, the daughter of GOP Rep. Andy Biggs.
www.phoenixnewtimes.com
August 7, 2025 at 2:33 PM
"Conservatism consists of exactly one proposition, to wit: There must be in-groups whom the law protects but does not bind, alongside out-groups whom the law binds but does not protect."
Reposted by Laura Stephen
Group leader positions in @sangerinstitute.bsky.social Cellular Genomics, led by @mhaniffa.bsky.social, to decode and recode human tissues. Broad net - clinical research, in vitro models, single cell, AI. Vibrant, supportive community. Please share!
sanger.wd103.myworkdayjobs.com/en-GB/Wellco...
sanger.wd103.myworkdayjobs.com/en-GB/Wellco...
July 31, 2025 at 7:56 AM
Group leader positions in @sangerinstitute.bsky.social Cellular Genomics, led by @mhaniffa.bsky.social, to decode and recode human tissues. Broad net - clinical research, in vitro models, single cell, AI. Vibrant, supportive community. Please share!
sanger.wd103.myworkdayjobs.com/en-GB/Wellco...
sanger.wd103.myworkdayjobs.com/en-GB/Wellco...