Lars Henning
@larshenningmd.bsky.social
80% gynecological oncologist Västerås 🇸🇪. 20% HTA-unit Camtö Örebro Hospital. Views my own. Too dumb and lazy for doing research but interested how to evaluate medical research&evidence.
Words matter. Dislike lifscience like QoL&D engl, swed, germ
Words matter. Dislike lifscience like QoL&D engl, swed, germ
Pinned
Lars Henning
@larshenningmd.bsky.social
· Dec 22
vardgivare.regionorebrolan.se/rapport-om-l...
Skrev i senaste "Rapport om läkemedel" från Läkemedelskommitén Örebro om Camtös systematiska översikt över torkat svinsköldkörtelextrakt mot hypotyreos och en kartläggning av dess förskrivning i Sverige. Så snygg illustrerat. Tacksam för kritisk läsning.
Skrev i senaste "Rapport om läkemedel" från Läkemedelskommitén Örebro om Camtös systematiska översikt över torkat svinsköldkörtelextrakt mot hypotyreos och en kartläggning av dess förskrivning i Sverige. Så snygg illustrerat. Tacksam för kritisk läsning.
9th of december free 2-hour introduction online workshop on the INSPECT-SR tool for assessing trustworthiness of randomised controlled trials (RCTs. 👇
November 6, 2025 at 6:02 PM
9th of december free 2-hour introduction online workshop on the INSPECT-SR tool for assessing trustworthiness of randomised controlled trials (RCTs. 👇
Detection for fabricated or unlikely data in RCT's should be mandatory for HTA-units as well 👇
i agree. Problem is that peer review is not geared up for detection of fabricated data. Sadly I think we need to be more alert to this. Inclusion of raw data v helpful in this case - and the discrepancies in age hit you as soon as you open the file. But deposited data should be .csv! @bmj.com
November 3, 2025 at 11:28 AM
Detection for fabricated or unlikely data in RCT's should be mandatory for HTA-units as well 👇
Reposted by Lars Henning
10/ Protecting every child protects the world. 🌍
That’s what vaccine equity means — a safer, fairer future for all.
Learn more:
🔹 The Lancet: tinyurl.com/3vbkwrfx
🔹 Nature: tinyurl.com/yc3v84uj
🔹 Gavi: gavi.org
#GlobalHealth
That’s what vaccine equity means — a safer, fairer future for all.
Learn more:
🔹 The Lancet: tinyurl.com/3vbkwrfx
🔹 Nature: tinyurl.com/yc3v84uj
🔹 Gavi: gavi.org
#GlobalHealth
November 2, 2025 at 12:07 PM
10/ Protecting every child protects the world. 🌍
That’s what vaccine equity means — a safer, fairer future for all.
Learn more:
🔹 The Lancet: tinyurl.com/3vbkwrfx
🔹 Nature: tinyurl.com/yc3v84uj
🔹 Gavi: gavi.org
#GlobalHealth
That’s what vaccine equity means — a safer, fairer future for all.
Learn more:
🔹 The Lancet: tinyurl.com/3vbkwrfx
🔹 Nature: tinyurl.com/yc3v84uj
🔹 Gavi: gavi.org
#GlobalHealth
Reposted by Lars Henning
Who did this?!
November 1, 2025 at 8:38 PM
Who did this?!
Good study which contributes to informed decision making of women when choosing contraceptives. But also an example of failed communication of research findings in the 🇸🇪 media. A school-book example imo where it should be forbidden to use relative risks and mandatory with absolute risk.
Both combined and progestin-only contraceptives are linked to increased breast cancer risk, with greater risk observed for progestin-only, particularly desogestrel-containing products. ja.ma/47lXKLe
November 2, 2025 at 8:44 AM
Good study which contributes to informed decision making of women when choosing contraceptives. But also an example of failed communication of research findings in the 🇸🇪 media. A school-book example imo where it should be forbidden to use relative risks and mandatory with absolute risk.
Reposted by Lars Henning
Evidence synthesis for decision making: navigating the chaos of the real world | Online
🗓️ 6 November
This webinar will discuss some of the challenges in evidence synthesis when the available evidence may not answer all the questions.
🔗 Register here: universityofgalway-ie.zoom.us/webinar/regi...
🗓️ 6 November
This webinar will discuss some of the challenges in evidence synthesis when the available evidence may not answer all the questions.
🔗 Register here: universityofgalway-ie.zoom.us/webinar/regi...
universityofgalway-ie.zoom.us
October 31, 2025 at 3:07 PM
Evidence synthesis for decision making: navigating the chaos of the real world | Online
🗓️ 6 November
This webinar will discuss some of the challenges in evidence synthesis when the available evidence may not answer all the questions.
🔗 Register here: universityofgalway-ie.zoom.us/webinar/regi...
🗓️ 6 November
This webinar will discuss some of the challenges in evidence synthesis when the available evidence may not answer all the questions.
🔗 Register here: universityofgalway-ie.zoom.us/webinar/regi...
Good example of nice description of disadvantages with multidisciplinary conferences in cancer-care and bad solutions (AI as the rescue). My 2 cents: centralization has gone too far. Invest in oncologists close to patients and listen to them and you'll do better decisions www.bmj.com/content/391/...
Cancer decision making needs a radical rethink
Long meetings involving dozens of clinicians can delay patient care and leave no room for service improvement. It’s time for a fresh approach, say Tom Roques and colleagues
For 30 years, multidiscip...
www.bmj.com
October 31, 2025 at 3:09 PM
Good example of nice description of disadvantages with multidisciplinary conferences in cancer-care and bad solutions (AI as the rescue). My 2 cents: centralization has gone too far. Invest in oncologists close to patients and listen to them and you'll do better decisions www.bmj.com/content/391/...
Debatt-artikel efter HTA-enhet Camtös rapport om exploderande CT-användning. Camtö uppmärksammade i rapporten att det saknas organiserad statistik om användning av CT där man var tvungen att använda framtagen data från ett företag
”Ökningen av CT behöver stoppas”
www.svd.se/a/5EAgP6/ove...
”Ökningen av CT behöver stoppas”
www.svd.se/a/5EAgP6/ove...
”Ökningen av CT behöver stoppas”
DEBATT. Överläkare: Sjukvården är fast i en farlig spiral där krav på perfektion, produktion och emellanåt omöjliga förutsättningar betalas med ett ökande antal CT-undersökningar.
www.svd.se
October 31, 2025 at 6:02 AM
Debatt-artikel efter HTA-enhet Camtös rapport om exploderande CT-användning. Camtö uppmärksammade i rapporten att det saknas organiserad statistik om användning av CT där man var tvungen att använda framtagen data från ett företag
”Ökningen av CT behöver stoppas”
www.svd.se/a/5EAgP6/ove...
”Ökningen av CT behöver stoppas”
www.svd.se/a/5EAgP6/ove...
Reposted by Lars Henning
This is an excellent point that generalizes.
Researchers often defend suboptimal practices by referring to future studies with better designs.
But: Why would anybody run those studies when you can just throw a bunch of variables into a regression and make sweeping "preliminary" claims?
Researchers often defend suboptimal practices by referring to future studies with better designs.
But: Why would anybody run those studies when you can just throw a bunch of variables into a regression and make sweeping "preliminary" claims?
October 28, 2025 at 11:22 AM
This is an excellent point that generalizes.
Researchers often defend suboptimal practices by referring to future studies with better designs.
But: Why would anybody run those studies when you can just throw a bunch of variables into a regression and make sweeping "preliminary" claims?
Researchers often defend suboptimal practices by referring to future studies with better designs.
But: Why would anybody run those studies when you can just throw a bunch of variables into a regression and make sweeping "preliminary" claims?
Sociologen @rolandpaulsen.bsky.social med mycket intressant berättelse om testosteron-industrins bakgrund och idéhistorie inklusive hänvisning till HTA-enheten CAMTÖ's debattartikel och ny boktips om överdiagnos
www.dn.se/kultur/rolan...
www.dn.se/kultur/rolan...
Roland Paulsen: Jag mätte mina testosteronhalter – resultatet var chockerande
Alla från Trump till Andrew Tate skryter med sina höga testosteronhalter. En dag började Roland Paulsen undra om han själv kanske behövde tillskott.
www.dn.se
October 26, 2025 at 11:04 AM
Sociologen @rolandpaulsen.bsky.social med mycket intressant berättelse om testosteron-industrins bakgrund och idéhistorie inklusive hänvisning till HTA-enheten CAMTÖ's debattartikel och ny boktips om överdiagnos
www.dn.se/kultur/rolan...
www.dn.se/kultur/rolan...
Dyra sprutan kan skydda mot demens
www.svd.se/a/OowPbb/bal...
Fascinerande artikel som ställer frågan om inte en välgjord observationsstudie som innefattar ett naturligt experiment skall vara tillräckligt för att introducera bältrosvaccination för äldre i svenska vaccinationsprogrammet.
www.svd.se/a/OowPbb/bal...
Fascinerande artikel som ställer frågan om inte en välgjord observationsstudie som innefattar ett naturligt experiment skall vara tillräckligt för att introducera bältrosvaccination för äldre i svenska vaccinationsprogrammet.
Dyra sprutan kan skydda mot demens
Vaccin mot bältros tycks minska risken för demens, enligt flera studier. Därför bör de dyra sprutorna nu införas i det svenska vaccinationsprogrammet, anser forskare.
www.svd.se
October 22, 2025 at 2:22 PM
Dyra sprutan kan skydda mot demens
www.svd.se/a/OowPbb/bal...
Fascinerande artikel som ställer frågan om inte en välgjord observationsstudie som innefattar ett naturligt experiment skall vara tillräckligt för att introducera bältrosvaccination för äldre i svenska vaccinationsprogrammet.
www.svd.se/a/OowPbb/bal...
Fascinerande artikel som ställer frågan om inte en välgjord observationsstudie som innefattar ett naturligt experiment skall vara tillräckligt för att introducera bältrosvaccination för äldre i svenska vaccinationsprogrammet.
Unfortunately sold out for now. But hopefully more free online workshops in the future
Free online workshop for assessing trustworthiness of RCTs
Introductory online INSPECT-SR workshop. November 6th, 12-2pm UK-time. Free, places limited. BOOK: www.trybooking.com/uk/events/la...
October 22, 2025 at 1:14 PM
Unfortunately sold out for now. But hopefully more free online workshops in the future
Still painful not to be able to read Cochrane Reviews during the first year in full. Much more painful that I wasted resources for far too many years with my misguided non-evidence routine to give blood transfusion to my cancer patients with Hb<100. #choosewisely
A Cochrane review found that, for most people, waiting for for their haemoglobin drop to lower levels before giving a transfusion was safe and means fewer transfusions in general.
🔗 www.cochranelibrary.com/cdsr/doi/10....
🔗 www.cochranelibrary.com/cdsr/doi/10....
October 21, 2025 at 10:37 AM
Still painful not to be able to read Cochrane Reviews during the first year in full. Much more painful that I wasted resources for far too many years with my misguided non-evidence routine to give blood transfusion to my cancer patients with Hb<100. #choosewisely
Reposted by Lars Henning
New blogpost on my concerns about Wellcome LEAP new $50m program on autism/microbiome links. deevybee.blogspot.com/2025/10/a-le...
#autism #microbiome #biomarkers #diagnostic
#autism #microbiome #biomarkers #diagnostic
A LEAP into the future, or off a cliff: Wellcome LEAP's new $50M program
A few days ago, I saw this post on LinkedIn: How does the gut microbiome shape early brain development? That’s what FORM, a new $50 million...
deevybee.blogspot.com
October 20, 2025 at 1:53 PM
New blogpost on my concerns about Wellcome LEAP new $50m program on autism/microbiome links. deevybee.blogspot.com/2025/10/a-le...
#autism #microbiome #biomarkers #diagnostic
#autism #microbiome #biomarkers #diagnostic
Open access for papers with general interest for patients and their families is as well a necessity. In this screenshot from X by Bishal Gyawali you get at least the first page of an important read if you are interested or in need of cancer research
October 19, 2025 at 10:23 AM
Open access for papers with general interest for patients and their families is as well a necessity. In this screenshot from X by Bishal Gyawali you get at least the first page of an important read if you are interested or in need of cancer research
Reposted by Lars Henning
Patient-, care partner-, and clinician-proposed solutions to address the time toxicity of cancer care
link.springer.com/article/10.1...
link.springer.com/article/10.1...
October 18, 2025 at 1:32 PM
Patient-, care partner-, and clinician-proposed solutions to address the time toxicity of cancer care
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Kommentarer lyfter debattartikeln utanför lilla gyn-onkologin. Min favorit-kommentar från Jörn Schneede Läkemedelscentrum Västerbotten. Tror ni att den här debatten kommer påverka hur svenska nationella vårdprogram tas fram?
lakartidningen.se/opinion/deba...
En av de tre klokaste gyn-onkologer vi har i Sverige har skrivit en viktig debattartikel . Docent Sahar Salehi från Karolinska om att våra patienter förtjänar bättre kommunikation angående evidensen bakom nationella vårdprogram och bättre nyfikenhetsdriven forskning
En av de tre klokaste gyn-onkologer vi har i Sverige har skrivit en viktig debattartikel . Docent Sahar Salehi från Karolinska om att våra patienter förtjänar bättre kommunikation angående evidensen bakom nationella vårdprogram och bättre nyfikenhetsdriven forskning
Riskfyllt när konsensus ersätter evidens i de nationella riktlinjerna
I stället för att utveckla interventioner som kan ge verklig patientnytta flyttas fokus till att avfärda åtgärder som införts på svaga grunder.
lakartidningen.se
October 16, 2025 at 7:08 PM
Kommentarer lyfter debattartikeln utanför lilla gyn-onkologin. Min favorit-kommentar från Jörn Schneede Läkemedelscentrum Västerbotten. Tror ni att den här debatten kommer påverka hur svenska nationella vårdprogram tas fram?
lakartidningen.se/opinion/deba...
En av de tre klokaste gyn-onkologer vi har i Sverige har skrivit en viktig debattartikel . Docent Sahar Salehi från Karolinska om att våra patienter förtjänar bättre kommunikation angående evidensen bakom nationella vårdprogram och bättre nyfikenhetsdriven forskning
En av de tre klokaste gyn-onkologer vi har i Sverige har skrivit en viktig debattartikel . Docent Sahar Salehi från Karolinska om att våra patienter förtjänar bättre kommunikation angående evidensen bakom nationella vårdprogram och bättre nyfikenhetsdriven forskning
Riskfyllt när konsensus ersätter evidens i de nationella riktlinjerna
I stället för att utveckla interventioner som kan ge verklig patientnytta flyttas fokus till att avfärda åtgärder som införts på svaga grunder.
lakartidningen.se
October 15, 2025 at 4:18 PM
lakartidningen.se/opinion/deba...
En av de tre klokaste gyn-onkologer vi har i Sverige har skrivit en viktig debattartikel . Docent Sahar Salehi från Karolinska om att våra patienter förtjänar bättre kommunikation angående evidensen bakom nationella vårdprogram och bättre nyfikenhetsdriven forskning
En av de tre klokaste gyn-onkologer vi har i Sverige har skrivit en viktig debattartikel . Docent Sahar Salehi från Karolinska om att våra patienter förtjänar bättre kommunikation angående evidensen bakom nationella vårdprogram och bättre nyfikenhetsdriven forskning
Reposted by Lars Henning
Health tests on the high street: Convenient or confusing?
Public Webinar 🗓️ Tuesday 14 October THIS EVENING 6-7pm
Register here www.eventbrite.com/e/health-tes...
This evening, we are presenting the findings of our evaluations of supermarket self tests, summarising our BMJ papers
Public Webinar 🗓️ Tuesday 14 October THIS EVENING 6-7pm
Register here www.eventbrite.com/e/health-tes...
This evening, we are presenting the findings of our evaluations of supermarket self tests, summarising our BMJ papers
October 14, 2025 at 11:40 AM
Health tests on the high street: Convenient or confusing?
Public Webinar 🗓️ Tuesday 14 October THIS EVENING 6-7pm
Register here www.eventbrite.com/e/health-tes...
This evening, we are presenting the findings of our evaluations of supermarket self tests, summarising our BMJ papers
Public Webinar 🗓️ Tuesday 14 October THIS EVENING 6-7pm
Register here www.eventbrite.com/e/health-tes...
This evening, we are presenting the findings of our evaluations of supermarket self tests, summarising our BMJ papers
Lite väl positiv framställning på P1 Fabriken av AI inom sjukvården och diagnostik. Jag rekommenderar istället på fredag Cantös temadag "Varför så bråttom?" med en föreläsning om "Evidensgranskning av AI-baserade och andra medicintekniska produkter" och "Lärdomar av sjukvårdens digitalisering"
October 6, 2025 at 6:07 PM
Lite väl positiv framställning på P1 Fabriken av AI inom sjukvården och diagnostik. Jag rekommenderar istället på fredag Cantös temadag "Varför så bråttom?" med en föreläsning om "Evidensgranskning av AI-baserade och andra medicintekniska produkter" och "Lärdomar av sjukvårdens digitalisering"
One of the most fascinating academic-driven concepts in oncology is de-escalation. As the rich countries lived delusionally as if their resources were unlimited we are starting to learn from countries like India. Swedish Society of Oncology changed for almost 2 yrs ago to weight-based immunotherapy
Bloomberg released an article highlighting efforts to reduce cancer drug doses while preserving outcomes & making treatments more affordable & accessible globally.
Read more: tinyurl.com/93n5xxvk
#CommonSenseOncology #CancerCare
Read more: tinyurl.com/93n5xxvk
#CommonSenseOncology #CancerCare
Pharma Is Pushing $200,000 Cancer Drugs When Cheaper Doses May Work
Doctors are experimenting with using lower doses of blockbuster cancer drugs. It could help hundreds of thousands of lives — if pharmaceutical companies would allow it.
tinyurl.com
October 4, 2025 at 6:17 AM
One of the most fascinating academic-driven concepts in oncology is de-escalation. As the rich countries lived delusionally as if their resources were unlimited we are starting to learn from countries like India. Swedish Society of Oncology changed for almost 2 yrs ago to weight-based immunotherapy
Big recommendation to watch Chris Booth on the CHALLENGE-RCT for everybody interested in cancer and exercise youtu.be/bZTBZ33JtoI?...
October 1, 2025 at 6:00 PM
Big recommendation to watch Chris Booth on the CHALLENGE-RCT for everybody interested in cancer and exercise youtu.be/bZTBZ33JtoI?...
Reposted by Lars Henning
I think I'd swallow arsenic before shopping at something called TrumpRx.
October 1, 2025 at 2:23 AM
I think I'd swallow arsenic before shopping at something called TrumpRx.
I witnessed yesterday probably for me the best presentation ever of a cancer trial listening to a @csoncol.bsky.social session about the CHALLENGE-trial by Chris Booth with a hell of a ride & tour de force in the Q&A. Very inspiring comments by @eaeisenhauer.bsky.social
www.nejm.org/doi/full/10....
www.nejm.org/doi/full/10....
Structured Exercise after Adjuvant Chemotherapy for Colon Cancer | NEJM
Preclinical and observational studies suggest that exercise may improve cancer outcomes.
However, definitive level 1 evidence is lacking. In this phase 3, randomized trial
conducted at 55 centers, ...
www.nejm.org
October 1, 2025 at 3:07 AM
I witnessed yesterday probably for me the best presentation ever of a cancer trial listening to a @csoncol.bsky.social session about the CHALLENGE-trial by Chris Booth with a hell of a ride & tour de force in the Q&A. Very inspiring comments by @eaeisenhauer.bsky.social
www.nejm.org/doi/full/10....
www.nejm.org/doi/full/10....