Kyla Ost
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kylaost.bsky.social
Kyla Ost
@kylaost.bsky.social
780 followers 240 following 5 posts
Microbiologist/immunologist, Assist. Prof at CU Anschutz, don’t forget the fungi!
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Reposted by Kyla Ost
drjorhodes.com
Fungal friends: The University of Minnesota is hiring a tenure track medical mycologist, with emphasis on emergence of pathogens, genomics and evolution!

www.nature.com/naturecareer...
New Assistant Professor: Tenure Track - Fungal Biology/Medical Mycology - Minneapolis, Minnesota job with University of Minnesota - Medical School | 12848307
About the Job: The Department of Microbiology & Immunology and the Institute on Infectious Diseases (UMIID) at the University of Minnesota Medical ...
www.nature.com
November 23, 2025 at 11:42 AM
Reposted by Kyla Ost
judith-behnsen.bsky.social
Excited to share our new publication, out today in Nature! www.nature.com/articles/s41.... @kanchanj.bsky.social led this fascinating fungal-bacterial interaction project. We are grateful for our wonderful collaborators Brian Peters and David Underhill.
Commensal yeast promotes Salmonella Typhimurium virulence - Nature
Commensal Candida albicans enhances the virulence and dissemination of Salmonella enterica subsp. enterica serovar Typhimurium.
www.nature.com
September 3, 2025 at 4:32 PM
Reposted by Kyla Ost
ascbiology.bsky.social
ASM, ASBMB, ASCB & FASEB are deeply disappointed in the Supreme Court ruling allowing cancellation of $800M in NIH grants, threatening labs, jobs, and early-career scientists. Stable funding is vital for U.S. science.

Read more: www.ascb.org/society-news...
Statement on Supreme Court Ruling in American Public Health Association v. NIH - ASCB
The American Society for Microbiology (ASM), the American Society for Biochemistry and Molecular Biology (ASBMB), the American Society for Cell Biology (ASCB) and the Federation of American Societies ...
www.ascb.org
August 22, 2025 at 7:44 PM
Reposted by Kyla Ost
fabricejpierre.bsky.social
"From novice to expert: preparing your peer review"

Worth a read! #microsky
From novice to expert: preparing your peer review | mBio
Peer review is the process that academic journals, conferences, and funding agencies use to ensure the quality of scholarly work before it is published, presented, or funded. Reviewers for academic jo...
journals.asm.org
June 5, 2025 at 3:04 PM
Reposted by Kyla Ost
plosbiology.org
#Fungal infections are hard to treat due to #DrugResistance. @blakebillmyre.bsky.social &co use a high-throughput #TNseq system in #Cryptococcus neoformans to identify >1400 essential genes & reveal a role for #mitochondrial genes in #fluconazole sensitivity @plosbiology.org 🧪 plos.io/4dz3iVm
Schematic of TN-seq in C. neoformans. Top left: Transposon insertions (orange arrow) into nonessential genes results in viable cells. In contrast, insertions into essential genes will result in dead and nonrecoverable cells. Top right: TN-seq works by generating a library of cells where each cell has a single independent transposon insertion in a random location. As in A, those insertions into essential regions cause the cells to die and are nonrecoverable. As a result, the total library (bottom) is depleted in insertions in essential regions. Bottom: The Ac/Ds transposon was split into an Ac transposase and a Ds transposon containing a neomycin resistance marker. This Ds transposon was integrated into an intron of URA5 and the Ac transposase was integrated into the safe haven locus. The resulting stain is ura− and neomycin resistant. Upon initiating transposition via growth on galactose, the strain becomes URA+ and mutant at another locus (depicted here as YFG1).
May 23, 2025 at 10:15 AM
Reposted by Kyla Ost
umichmicroimmuno.bsky.social
www.sciencedirect.com/science/arti... @drbadbug.bsky.social @teresaomeara.bsky.social Overall, our findings illustrate non-canonical IRE1α activation during infection and a function for IRE1α in supporting organelle contact sites to safeguard against rapidly growing microbes.
IRE1α promotes phagosomal calcium flux to enhance macrophage fungicidal activity
The mammalian endoplasmic reticulum (ER) stress sensor inositol-requiring enzyme 1α (IRE1α) is essential for cellular homeostasis and plays key roles …
www.sciencedirect.com
May 12, 2025 at 8:27 PM
Reposted by Kyla Ost
asiya-gusa.bsky.social
Excited to announce Duke’s inaugural Climate and Fungi Symposium May 16, 2025! Please register for in-person or virtual 🍄 mgm.duke.edu/about-mgm/se...
Fungi in a Warming World: Adaptations, Challenges, and Resilience | Duke Department of Molecular Genetics and Microbiology
mgm.duke.edu
April 18, 2025 at 1:10 AM
Reposted by Kyla Ost
redpenblackpen.bsky.social
A reminder in these hard times. #sciencestrong
Cartoon showing a woman looking in to a microscope saying "Whoaah!!!" The caption states "The best part of Science is knowing, for a moment, something that nobody else in the world knows"
February 19, 2025 at 6:14 AM
Reposted by Kyla Ost
lozanzi.bsky.social
#EveryCellIsAnImmuneCell! June Round &friends show @science.org that in early life bacteria & fungi cooperate to expand insulin producing β islets via macrophage infiltration & that recognition of commensal yeast cell wall can protects against diabetes in adults! www.science.org/doi/10.1126/...
Neonatal fungi promote lifelong metabolic health through macrophage-dependent β cell development
Loss of early-life microbial diversity is correlated with diabetes, yet mechanisms by which microbes influence disease remain elusive. We report a critical neonatal window in mice when microbiota disr...
www.science.org
March 12, 2025 at 5:12 PM
Reposted by Kyla Ost
mrccmm.bsky.social
Join us for this month's #MycoTalks with Rebecca Shapiro and Guilhem Janbon

📅Thursday 27 March
🕓16:00 GMT

Register here: universityofexeter.zoom.us/webinar/regi...
March 12, 2025 at 3:02 PM
kylaost.bsky.social
Early life colonization with an understudied Candida species promotes long term metabolic health. This still blows my mind - congrats Jen and team! Thrilled to have played a very smal part (mostly as your fungal cheerleader)
March 7, 2025 at 9:06 PM
Reposted by Kyla Ost
balloulab.bsky.social
PhD studentship for UK citizens! Understand how Endosymbionts Impact Mucoralean Fungi Drug Resistance Profiles. These are devastating invasive fungal infections that need urgent research. Work with my team @mrccmm.bsky.social, @forestcita.bsky.social, and UKDSTL
www.surrey.ac.uk/bbsrc-wessex...
BBSRC Wessex One Health (WOH) Doctoral Landscape Award | University of Surrey
17 PhD studentships for October 2025 start: Interdisciplinary approaches to Infection Biosciences to combat disease threats to human and animal health.
www.surrey.ac.uk
January 30, 2025 at 2:49 PM
Reposted by Kyla Ost
drvalleyfever.bsky.social
Great summary of the history of progress. Let’s not go quietly back to the dark ages.
jeremymberg.bsky.social Jeremy Berg @jeremymberg.bsky.social · Jan 31
A special Bluetorial about one of my mentors Ruth Kirschstein

Among Ruth Kirschstein’s many contributions to American science was the development and expansion of programs intended to increase participation of people from groups underrepresented in biomedical research.
a cartoon says hey everybody an old man 's talking while bart simpson looks on
ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on
media.tenor.com
February 1, 2025 at 1:21 AM
Reposted by Kyla Ost
lucyxie.bsky.social
Excited to share my postdoc work now on bioRxiv!

www.biorxiv.org/content/10.1...

We discovered a non-genetic drug-adapted state that emerges frequently in the the human fungal pathogen Candida albicans.

1/6
Stress-driven emergence of heritable non-genetic drug resistance
Drug resistance is the chief cause of treatment failure for therapies targeting chronic and infectious diseases. Whether the emergence of resistance is accelerated by environmental exposure to low lev...
www.biorxiv.org
December 23, 2024 at 12:19 PM
Reposted by Kyla Ost
lozanzi.bsky.social
#LocationLocationLocation! Gribonika, Belkaid &co shows @ Nature that skin colonization by Staph epi activates Langerhans cells driving Abs in lymph nodes, & also in skin autonomous lymphoid organs that independently produce Abs protecting against systemic infections! www.nature.com/articles/s41...
Skin autonomous antibody production regulates host-microbiota interactions - Nature
Nature - Skin autonomous antibody production regulates host-microbiota interactions
www.nature.com
December 11, 2024 at 7:59 PM
Reposted by Kyla Ost
sydneyglassman.bsky.social
My department is hiring a fungal biologist! aprecruit.ucr.edu/JPF01990
Assistant Professor in Fungal Biology
University of California, Riverside is hiring. Apply now!
aprecruit.ucr.edu
December 10, 2024 at 7:14 PM
kylaost.bsky.social
Huge congratulations to my PhD advisor! So excited for him and Duke ID medicine.duke.edu/news/dr-jame...
Dr. James Andrew Alspaugh Named Chief of Infectious Diseases Division
James Andrew “Andy” Alspaugh, MD, has been appointed as the new chief for the Division of Infectious Diseases, effective December 9, 2024.
medicine.duke.edu
December 4, 2024 at 7:31 PM
Reposted by Kyla Ost
mcsymbiont.bsky.social
Microbial people! Especially postdocs and maybe some assistant professors who are feeling antsy ... the University of Montana is doing a search for a microbiologist! This is a great department, in a great place. (I worked there for 10 years, loved it, ping me with Qs)

apply.interfolio.com/159494
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November 19, 2024 at 7:27 PM