Kaspar Bachmann
@kasparbachmann.bsky.social
MD | ICU Physician & Researcher
Passionate about gastrointestinal dysfunction, nutrition as well as ECMO and cardiopulmonary physiology. Enthusiast in #MatLab, signal analysis and data-driven research: https://pubmed.ncbi.nlm.nih.gov/?term=Kaspar+bachman
Passionate about gastrointestinal dysfunction, nutrition as well as ECMO and cardiopulmonary physiology. Enthusiast in #MatLab, signal analysis and data-driven research: https://pubmed.ncbi.nlm.nih.gov/?term=Kaspar+bachman
Thanks for sharing our review! Monitoring GI function when initiating / stepping up nutrition is key to prevent harm from too aggressive nutrition.
GI function & nutrition in septic shock
➡️ Stabilise perfusion first, then start low-dose EN and advance as tolerated
➡️ Early aggressive EN can harm; monitor EFI and use PN if EN unsafe
CCR Journal Watch
https://criticalcarereviews.com/latest-evidence/journal-watch
➡️ Stabilise perfusion first, then start low-dose EN and advance as tolerated
➡️ Early aggressive EN can harm; monitor EFI and use PN if EN unsafe
CCR Journal Watch
https://criticalcarereviews.com/latest-evidence/journal-watch
November 1, 2025 at 7:12 AM
Thanks for sharing our review! Monitoring GI function when initiating / stepping up nutrition is key to prevent harm from too aggressive nutrition.
Reposted by Kaspar Bachmann
New 📝
We know RV dysfunction occurs on VV-ECMO in ARDS despite ECMO mitigating many of the traditional RV dysfunction risk factors (hypercapnia etc)
We don’t understand RV function dynamically over time on ECMO…
We know RV dysfunction occurs on VV-ECMO in ARDS despite ECMO mitigating many of the traditional RV dysfunction risk factors (hypercapnia etc)
We don’t understand RV function dynamically over time on ECMO…
April 21, 2025 at 12:07 PM
New 📝
We know RV dysfunction occurs on VV-ECMO in ARDS despite ECMO mitigating many of the traditional RV dysfunction risk factors (hypercapnia etc)
We don’t understand RV function dynamically over time on ECMO…
We know RV dysfunction occurs on VV-ECMO in ARDS despite ECMO mitigating many of the traditional RV dysfunction risk factors (hypercapnia etc)
We don’t understand RV function dynamically over time on ECMO…
Reposted by Kaspar Bachmann
@gurujosh.bsky.social presents the results of the MSSA domain of the SNAP 🫰 trial at #ESCMID2025
fluclox caused more acute kidney injury than cefazolin; early mortality favored cefazolin
Absolutely Herculean effort by the entire global trial team and practice changing data #teamcefazolin
fluclox caused more acute kidney injury than cefazolin; early mortality favored cefazolin
Absolutely Herculean effort by the entire global trial team and practice changing data #teamcefazolin
April 12, 2025 at 3:00 PM
@gurujosh.bsky.social presents the results of the MSSA domain of the SNAP 🫰 trial at #ESCMID2025
fluclox caused more acute kidney injury than cefazolin; early mortality favored cefazolin
Absolutely Herculean effort by the entire global trial team and practice changing data #teamcefazolin
fluclox caused more acute kidney injury than cefazolin; early mortality favored cefazolin
Absolutely Herculean effort by the entire global trial team and practice changing data #teamcefazolin
Reposted by Kaspar Bachmann
Have you ever wondered what it takes before a clinical trial ends up in your timeline?
Well… we recently published the DDx-BRO trial ⬇️
Here is a 🧵 of its lifecycle: from 💡to 🏁, well, if the latter actually exists.
Well… we recently published the DDx-BRO trial ⬇️
Here is a 🧵 of its lifecycle: from 💡to 🏁, well, if the latter actually exists.
Diagnoses supported by a computerised diagnostic decision support system versus conventional diagnoses in emergency patients (DDX-BRO): a multicentre, multiple-period, double-blind, cluster-randomised...
Use of a CDDSS did not reduce the occurrence of diagnostic quality risk compared with
the usual diagnostic process in adults presenting to emergency departments. Future
research should aim to identify...
www.thelancet.com
March 18, 2025 at 10:44 PM
Have you ever wondered what it takes before a clinical trial ends up in your timeline?
Well… we recently published the DDx-BRO trial ⬇️
Here is a 🧵 of its lifecycle: from 💡to 🏁, well, if the latter actually exists.
Well… we recently published the DDx-BRO trial ⬇️
Here is a 🧵 of its lifecycle: from 💡to 🏁, well, if the latter actually exists.
Reposted by Kaspar Bachmann
Core outcome set of daily monitoring of gastrointestinal function in adult critically ill patients: a modified Delphi consensus process (COSMOGI)
Thanks to @criticalcarereviews.com
ccforum.biomedcentral.com/articles/10....
Thanks to @criticalcarereviews.com
ccforum.biomedcentral.com/articles/10....
Core outcome set of daily monitoring of gastrointestinal function in adult critically ill patients: a modified Delphi consensus process (COSMOGI) - Critical Care
Purpose Gastrointestinal (GI) dysfunction is common in critically ill patients and associated with poor outcomes. There is a lack of standardised methods for daily monitoring of GI function. COSMOGI a...
ccforum.biomedcentral.com
December 23, 2024 at 4:35 PM
Core outcome set of daily monitoring of gastrointestinal function in adult critically ill patients: a modified Delphi consensus process (COSMOGI)
Thanks to @criticalcarereviews.com
ccforum.biomedcentral.com/articles/10....
Thanks to @criticalcarereviews.com
ccforum.biomedcentral.com/articles/10....
January 3, 2025 at 10:31 AM
Reposted by Kaspar Bachmann
I got tired of opening a dozen PDFs to find the ECMO pressure/flow curve I need.
So I made an app!
Choose the cannula/size and you can see the max flow for a given pressure drop. Or compare multiple different cannula.
Lmk what ya’ll think. Useful? What’s it need?
onepagericu.com/ecmo-calcula...
So I made an app!
Choose the cannula/size and you can see the max flow for a given pressure drop. Or compare multiple different cannula.
Lmk what ya’ll think. Useful? What’s it need?
onepagericu.com/ecmo-calcula...
December 31, 2024 at 7:07 PM
I got tired of opening a dozen PDFs to find the ECMO pressure/flow curve I need.
So I made an app!
Choose the cannula/size and you can see the max flow for a given pressure drop. Or compare multiple different cannula.
Lmk what ya’ll think. Useful? What’s it need?
onepagericu.com/ecmo-calcula...
So I made an app!
Choose the cannula/size and you can see the max flow for a given pressure drop. Or compare multiple different cannula.
Lmk what ya’ll think. Useful? What’s it need?
onepagericu.com/ecmo-calcula...
Reposted by Kaspar Bachmann
Let us start 2025 in a positive mood: here are 10 methods things researchers can worry *less* about in 2025
a countdown clock with the number 10 in the center
ALT: a countdown clock with the number 10 in the center
media.tenor.com
December 23, 2024 at 10:36 AM
Let us start 2025 in a positive mood: here are 10 methods things researchers can worry *less* about in 2025
Reposted by Kaspar Bachmann
ICYMI #emimcc
Next chapter is live!
Non-invasive correlates of pulmonary artery pressures, by Sergio Caravita.
shockwaves.icu
@maxhockstein.bsky.social @zentensivist.bsky.social
Non-invasive correlates of pulmonary artery pressures, by Sergio Caravita.
shockwaves.icu
@maxhockstein.bsky.social @zentensivist.bsky.social
December 23, 2024 at 5:33 PM
ICYMI #emimcc
Reposted by Kaspar Bachmann
This was a fun study leveraging social media to demonstrate the high prevalence in Impella malrotation among cases shared on old Twitter.
If it's malrotated, but it works well, without suction alarms or other problems, do you change it? #cccsky #cardiosky #emimcc
www.pcronline.com/News/Whats-n...
If it's malrotated, but it works well, without suction alarms or other problems, do you change it? #cccsky #cardiosky #emimcc
www.pcronline.com/News/Whats-n...
Impella percutaneous ventricular assist device malrotation in social media: a call to action
This study suggests that correct Impella orientation is often overlooked, and that Impella malrotation is a common issue in real-world clinical practice, potentially associated with relevant complicat...
www.pcronline.com
December 20, 2024 at 8:14 PM
This was a fun study leveraging social media to demonstrate the high prevalence in Impella malrotation among cases shared on old Twitter.
If it's malrotated, but it works well, without suction alarms or other problems, do you change it? #cccsky #cardiosky #emimcc
www.pcronline.com/News/Whats-n...
If it's malrotated, but it works well, without suction alarms or other problems, do you change it? #cccsky #cardiosky #emimcc
www.pcronline.com/News/Whats-n...
Fresh off the press: COSMOGI 🗞️🗞️🔥🔥
What variables should we use to daily monitor #gastrointestinal function in #criticalcare?
We have developed a core outcome set and have defined 13 variables for daily GI assessment. Published today in Critical Care:
ccforum.biomedcentral.com/articles/10....
What variables should we use to daily monitor #gastrointestinal function in #criticalcare?
We have developed a core outcome set and have defined 13 variables for daily GI assessment. Published today in Critical Care:
ccforum.biomedcentral.com/articles/10....
Core outcome set of daily monitoring of gastrointestinal function in adult critically ill patients: a modified Delphi consensus process (COSMOGI) - Critical Care
Purpose Gastrointestinal (GI) dysfunction is common in critically ill patients and associated with poor outcomes. There is a lack of standardised methods for daily monitoring of GI function. COSMOGI a...
ccforum.biomedcentral.com
December 18, 2024 at 4:58 PM
Fresh off the press: COSMOGI 🗞️🗞️🔥🔥
What variables should we use to daily monitor #gastrointestinal function in #criticalcare?
We have developed a core outcome set and have defined 13 variables for daily GI assessment. Published today in Critical Care:
ccforum.biomedcentral.com/articles/10....
What variables should we use to daily monitor #gastrointestinal function in #criticalcare?
We have developed a core outcome set and have defined 13 variables for daily GI assessment. Published today in Critical Care:
ccforum.biomedcentral.com/articles/10....
Reposted by Kaspar Bachmann
#MedSky #EMIMCC #IDsky #cardiosky
@pulmcrit.bsky.social
What is the culture at your hospital for potassium replacement?
At most hospitals I'm at it seems to be a culture of replace to K 4.0 and the individual doctor makes the call.
This paper confirms my bias...
jamanetwork.com/journals/jam...
@pulmcrit.bsky.social
What is the culture at your hospital for potassium replacement?
At most hospitals I'm at it seems to be a culture of replace to K 4.0 and the individual doctor makes the call.
This paper confirms my bias...
jamanetwork.com/journals/jam...
Potassium Supplementation and Prevention of Atrial Fibrillation After Cardiac Surgery
This randomized clinical trial examines whether a lower serum potassium concentration trigger for supplementation is noninferior to a high-normal trigger for the prevention of atrial fibrillation afte...
jamanetwork.com
December 17, 2024 at 12:11 AM
#MedSky #EMIMCC #IDsky #cardiosky
@pulmcrit.bsky.social
What is the culture at your hospital for potassium replacement?
At most hospitals I'm at it seems to be a culture of replace to K 4.0 and the individual doctor makes the call.
This paper confirms my bias...
jamanetwork.com/journals/jam...
@pulmcrit.bsky.social
What is the culture at your hospital for potassium replacement?
At most hospitals I'm at it seems to be a culture of replace to K 4.0 and the individual doctor makes the call.
This paper confirms my bias...
jamanetwork.com/journals/jam...
Reposted by Kaspar Bachmann
Results of the #SAHARAtrial released after #CCRdownunder. A lot to discuss…
www.nejm.org/doi/full/10....
#neurocriticalcare
www.nejm.org/doi/full/10....
#neurocriticalcare
Liberal or Restrictive Transfusion Strategy in Aneurysmal Subarachnoid Hemorrhage | NEJM
The effect of a liberal red-cell transfusion strategy as compared with a restrictive
strategy in patients during the critical care period after an aneurysmal subarachnoid
hemorrhage is unclear. We ...
www.nejm.org
December 10, 2024 at 11:16 AM
Results of the #SAHARAtrial released after #CCRdownunder. A lot to discuss…
www.nejm.org/doi/full/10....
#neurocriticalcare
www.nejm.org/doi/full/10....
#neurocriticalcare
December 11, 2024 at 10:41 PM
Reposted by Kaspar Bachmann
#ADAPTtrial released & the results are interesting…
Compared to SOC, Procalcitonin guided antibiotics in sepsis resulted in:
- FEWER antibiotic days: 10.7 vs 9.8 (p=0.01) BUT
- HIGHER 28 day mortality: 19.4% vs 20.9% (p=0.02) though this did not meet the pre-specified non-inferiority margin
🤔
1/
Compared to SOC, Procalcitonin guided antibiotics in sepsis resulted in:
- FEWER antibiotic days: 10.7 vs 9.8 (p=0.01) BUT
- HIGHER 28 day mortality: 19.4% vs 20.9% (p=0.02) though this did not meet the pre-specified non-inferiority margin
🤔
1/
December 9, 2024 at 10:58 PM
#ADAPTtrial released & the results are interesting…
Compared to SOC, Procalcitonin guided antibiotics in sepsis resulted in:
- FEWER antibiotic days: 10.7 vs 9.8 (p=0.01) BUT
- HIGHER 28 day mortality: 19.4% vs 20.9% (p=0.02) though this did not meet the pre-specified non-inferiority margin
🤔
1/
Compared to SOC, Procalcitonin guided antibiotics in sepsis resulted in:
- FEWER antibiotic days: 10.7 vs 9.8 (p=0.01) BUT
- HIGHER 28 day mortality: 19.4% vs 20.9% (p=0.02) though this did not meet the pre-specified non-inferiority margin
🤔
1/
The #Renovate Trial was just published. Kudos to the authors for this large trial.
HFNO was non-inferior to NIPPV in 1776 patients with acute respiratory failure. I have some comments and discussions; feel free to join in. 👇 1/n
#emimcc #ccr
HFNO was non-inferior to NIPPV in 1776 patients with acute respiratory failure. I have some comments and discussions; feel free to join in. 👇 1/n
#emimcc #ccr
High-flow nasal oxygen was noninferior to noninvasive ventilation for rates of endotracheal intubation or death within 7 days in 4 of the 5 patient groups with acute respiratory failure.
#CCRdownunder @criticalcarereviews.com
ja.ma/41s0Lbx
#CCRdownunder @criticalcarereviews.com
ja.ma/41s0Lbx
December 11, 2024 at 8:34 PM
Reposted by Kaspar Bachmann
It's amazing that Esmolol can show such consistency in effect size that has never been seen in sepsis, while Landiolol has a natural variation across trials. Add to that that the single trials vary more than the larger multicenter trials and one might almost get suspicious... #emimcc
December 11, 2024 at 9:54 AM
It's amazing that Esmolol can show such consistency in effect size that has never been seen in sepsis, while Landiolol has a natural variation across trials. Add to that that the single trials vary more than the larger multicenter trials and one might almost get suspicious... #emimcc
Reposted by Kaspar Bachmann
1/
Anemia happens frequently in our aSAH patients.
These patients are at risk for delayed cerebral ischemia and other neurologic insults
It would seem having adequate oxygen to the brain tissue would be a good thing to prevent such injury.
But how much hgb is adequate?
A #skytorial on SAHARA
Anemia happens frequently in our aSAH patients.
These patients are at risk for delayed cerebral ischemia and other neurologic insults
It would seem having adequate oxygen to the brain tissue would be a good thing to prevent such injury.
But how much hgb is adequate?
A #skytorial on SAHARA
December 10, 2024 at 6:30 PM
1/
Anemia happens frequently in our aSAH patients.
These patients are at risk for delayed cerebral ischemia and other neurologic insults
It would seem having adequate oxygen to the brain tissue would be a good thing to prevent such injury.
But how much hgb is adequate?
A #skytorial on SAHARA
Anemia happens frequently in our aSAH patients.
These patients are at risk for delayed cerebral ischemia and other neurologic insults
It would seem having adequate oxygen to the brain tissue would be a good thing to prevent such injury.
But how much hgb is adequate?
A #skytorial on SAHARA
Reposted by Kaspar Bachmann
#PCCMSky Update
146 members- only 4 more slots in this starter pack
Repost so the noobs know who the cool PCCM kids are
Reply if you are not included and should be (make sure your creds are in your bio I am not putting randos on here)
go.bsky.app/88wg6oG
146 members- only 4 more slots in this starter pack
Repost so the noobs know who the cool PCCM kids are
Reply if you are not included and should be (make sure your creds are in your bio I am not putting randos on here)
go.bsky.app/88wg6oG
December 10, 2024 at 12:51 PM
#PCCMSky Update
146 members- only 4 more slots in this starter pack
Repost so the noobs know who the cool PCCM kids are
Reply if you are not included and should be (make sure your creds are in your bio I am not putting randos on here)
go.bsky.app/88wg6oG
146 members- only 4 more slots in this starter pack
Repost so the noobs know who the cool PCCM kids are
Reply if you are not included and should be (make sure your creds are in your bio I am not putting randos on here)
go.bsky.app/88wg6oG
Reposted by Kaspar Bachmann
jamanetwork.com/journals/jam... ADAPT-SEPSIS just published in JAMA #ccrdownunder
Biomarker-Guided Antibiotic Duration for Patients With Suspected Sepsis
This clinical trial assessed whether treatment protocols for monitoring C-reactive protein or procalcitonin safely reduced the amount of time critically ill adults with suspected sepsis received antib...
jamanetwork.com
December 9, 2024 at 10:17 PM
jamanetwork.com/journals/jam... ADAPT-SEPSIS just published in JAMA #ccrdownunder
Reposted by Kaspar Bachmann
👇ICU strain is measurable & impacts outcomes.
“Measuring the Impact of ICU Strain on Mortality, After-Hours Discharge, Discharge Delay, Interhospital Transfer, and Readmission in Australia With the Activity Index.” David Pilcher et al.
🩺Critical Care Medicine.
🔗 journals.lww.com/ccmjournal/f...
“Measuring the Impact of ICU Strain on Mortality, After-Hours Discharge, Discharge Delay, Interhospital Transfer, and Readmission in Australia With the Activity Index.” David Pilcher et al.
🩺Critical Care Medicine.
🔗 journals.lww.com/ccmjournal/f...
Measuring the Impact of ICU Strain on Mortality,... : Critical Care Medicine
tive national registry-based cohort study.
SETTING:
One hundred seventy-five public and private hospitals in Australia (June 2020 through March 2022).
SUBJECTS:
Two hundred seventy-seven thousan...
journals.lww.com
November 17, 2023 at 5:02 AM
👇ICU strain is measurable & impacts outcomes.
“Measuring the Impact of ICU Strain on Mortality, After-Hours Discharge, Discharge Delay, Interhospital Transfer, and Readmission in Australia With the Activity Index.” David Pilcher et al.
🩺Critical Care Medicine.
🔗 journals.lww.com/ccmjournal/f...
“Measuring the Impact of ICU Strain on Mortality, After-Hours Discharge, Discharge Delay, Interhospital Transfer, and Readmission in Australia With the Activity Index.” David Pilcher et al.
🩺Critical Care Medicine.
🔗 journals.lww.com/ccmjournal/f...
Reposted by Kaspar Bachmann
Skytorial: pH management in DKA!
I've been following debates about this for a *long* time
(eg wrote this blog in 2016, which stands up pretty darn well: emcrit.org/pulmcrit/bic...)
after years of arguing, lemme break down my take on this 😁
I've been following debates about this for a *long* time
(eg wrote this blog in 2016, which stands up pretty darn well: emcrit.org/pulmcrit/bic...)
after years of arguing, lemme break down my take on this 😁
a cartoon of donald duck with the words " do you want to fight lets get it on then "
ALT: a cartoon of donald duck with the words " do you want to fight lets get it on then "
media.tenor.com
December 6, 2024 at 8:55 PM
Skytorial: pH management in DKA!
I've been following debates about this for a *long* time
(eg wrote this blog in 2016, which stands up pretty darn well: emcrit.org/pulmcrit/bic...)
after years of arguing, lemme break down my take on this 😁
I've been following debates about this for a *long* time
(eg wrote this blog in 2016, which stands up pretty darn well: emcrit.org/pulmcrit/bic...)
after years of arguing, lemme break down my take on this 😁
December 6, 2024 at 3:21 PM
Are you interested in #Sustainability in #Anesthesiology and how reusing TIVA lines could help reduce greenhouse gas emissions? Per Werner Moller, originally an expert in #AppliedPhysiology and #VenousReturn, discusses their environmental paper on the #EJA podcast.
open.spotify.com/episode/2RCa...
open.spotify.com/episode/2RCa...
December 3, 2024 at 9:36 PM
Are you interested in #Sustainability in #Anesthesiology and how reusing TIVA lines could help reduce greenhouse gas emissions? Per Werner Moller, originally an expert in #AppliedPhysiology and #VenousReturn, discusses their environmental paper on the #EJA podcast.
open.spotify.com/episode/2RCa...
open.spotify.com/episode/2RCa...