José Delgado, Ph.D.
@jmdelgado.bsky.social
Studying mitochondrial responses to infection at UCLA | Mitochondriac | Autophagy| DEI | Outdoor enthusiast | he/él | 🇲🇽⛰🚴🏼🏳️🌈
https://josedelgadophd.wixsite.com/jose
https://josedelgadophd.wixsite.com/jose
🚨 New work out from the Pernas Lab. Congratulations to my labmate Chahat Mehra!!
Host organelle - pathogen membrane contact sites!! ER edition!
rdcu.be/eRKUM
Host organelle - pathogen membrane contact sites!! ER edition!
rdcu.be/eRKUM
Toxoplasma effector TgROP1 establishes membrane contact sites with the endoplasmic reticulum during infection
Nature Microbiology - The Toxoplasma gondii effector TgROP1 mimics host factors to bind VAPA/B, thereby establishing parasite–host ER contact sites.
rdcu.be
November 25, 2025 at 5:24 PM
🚨 New work out from the Pernas Lab. Congratulations to my labmate Chahat Mehra!!
Host organelle - pathogen membrane contact sites!! ER edition!
rdcu.be/eRKUM
Host organelle - pathogen membrane contact sites!! ER edition!
rdcu.be/eRKUM
Reposted by José Delgado, Ph.D.
Applications are open for the Postdoctoral Enrichment Program (PDEP)—supporting postdocs as they advance cutting-edge research and build thriving scientific careers.
Learn more & apply: bwfund.org/pdep #bwfpdep
Learn more & apply: bwfund.org/pdep #bwfpdep
November 14, 2025 at 7:26 PM
Applications are open for the Postdoctoral Enrichment Program (PDEP)—supporting postdocs as they advance cutting-edge research and build thriving scientific careers.
Learn more & apply: bwfund.org/pdep #bwfpdep
Learn more & apply: bwfund.org/pdep #bwfpdep
Reposted by José Delgado, Ph.D.
Supervisors who invest in positive mentoring relationships with their PhD candidates also reap the benefits for their own research
go.nature.com/4hriohE
go.nature.com/4hriohE
What makes PhD students happy? Good supervision
Supervisors who invest in positive mentoring relationships with their PhD candidates also reap the benefits for their own research.
go.nature.com
October 22, 2025 at 9:53 AM
Supervisors who invest in positive mentoring relationships with their PhD candidates also reap the benefits for their own research
go.nature.com/4hriohE
go.nature.com/4hriohE
Reposted by José Delgado, Ph.D.
Last year, we helped 100 students save $31K in grad school app fees, giving students from underserved communities the freedom to apply widely.
This year we lost 16 partners = $8.2K setback = 110 fewer dreams.
🎓 You can change that.
💸 Donate to open 110 new doors.
givebutter.com/supportCL
This year we lost 16 partners = $8.2K setback = 110 fewer dreams.
🎓 You can change that.
💸 Donate to open 110 new doors.
givebutter.com/supportCL
October 13, 2025 at 7:17 PM
Last year, we helped 100 students save $31K in grad school app fees, giving students from underserved communities the freedom to apply widely.
This year we lost 16 partners = $8.2K setback = 110 fewer dreams.
🎓 You can change that.
💸 Donate to open 110 new doors.
givebutter.com/supportCL
This year we lost 16 partners = $8.2K setback = 110 fewer dreams.
🎓 You can change that.
💸 Donate to open 110 new doors.
givebutter.com/supportCL
Reposted by José Delgado, Ph.D.
NEXT WEEK: Applying to grad programs in the sciences? 🧬✨
Hear directly from university administrators about the key do’s and don’ts for a standout application.
Join our Faculty Panel for practical advice & answers to your questions.
📅 10/7, 11am ET
📍 Register: www.eventbrite.com/e/faculty-pa...
Hear directly from university administrators about the key do’s and don’ts for a standout application.
Join our Faculty Panel for practical advice & answers to your questions.
📅 10/7, 11am ET
📍 Register: www.eventbrite.com/e/faculty-pa...
October 1, 2025 at 4:05 PM
NEXT WEEK: Applying to grad programs in the sciences? 🧬✨
Hear directly from university administrators about the key do’s and don’ts for a standout application.
Join our Faculty Panel for practical advice & answers to your questions.
📅 10/7, 11am ET
📍 Register: www.eventbrite.com/e/faculty-pa...
Hear directly from university administrators about the key do’s and don’ts for a standout application.
Join our Faculty Panel for practical advice & answers to your questions.
📅 10/7, 11am ET
📍 Register: www.eventbrite.com/e/faculty-pa...
Reposted by José Delgado, Ph.D.
Ribonucleotide incorporation into mitochondrial DNA drives inflammation
www.nature.com/articles/s41...
Congratulations to the Langer lab @mpiage.bsky.social, Amir, and the rest of the team!
www.nature.com/articles/s41...
Congratulations to the Langer lab @mpiage.bsky.social, Amir, and the rest of the team!
Ribonucleotide incorporation into mitochondrial DNA drives inflammation - Nature
Imbalanced nucleotide metabolism leads to age- and mtDNA-dependent inflammatory responses and senescence-associated secretory phenotype in senescence.
www.nature.com
September 24, 2025 at 4:31 PM
Ribonucleotide incorporation into mitochondrial DNA drives inflammation
www.nature.com/articles/s41...
Congratulations to the Langer lab @mpiage.bsky.social, Amir, and the rest of the team!
www.nature.com/articles/s41...
Congratulations to the Langer lab @mpiage.bsky.social, Amir, and the rest of the team!
Reposted by José Delgado, Ph.D.
Our new collection offers cell biologists practical, expert-driven guidance and best practices in the design, execution, and analysis of experiments, and the subsequent communication of their results to their peers. 👉 rupress.org/jcb/collecti...
#Reproducibility
#Reproducibility
September 3, 2025 at 2:15 PM
Our new collection offers cell biologists practical, expert-driven guidance and best practices in the design, execution, and analysis of experiments, and the subsequent communication of their results to their peers. 👉 rupress.org/jcb/collecti...
#Reproducibility
#Reproducibility
Reposted by José Delgado, Ph.D.
Join me in donating to ABRCMS. For many of us early in our careers (and for many of us now), this is THE conference. Let’s make sure future generations get the same experience.
I was told if each poster judge donated $25, their goal would be quickly met, but I think we can do better! 🙏🏾💪🏾
I was told if each poster judge donated $25, their goal would be quickly met, but I think we can do better! 🙏🏾💪🏾
Calling all @apsphysiology.bsky.social members: let’s help raise some money to support ABRCMS student presentation awards! Goal is $1200/discipline to support 12 awards by Sept 30th! 🧪 abrcms.org/donate/stude...
ABRCMS Fundraising - Student Presentation Awards - ABRCMS
Judges – Help Us Raise Funds for Student Presentation Awards Thank you for your service as a judge at ABRCMS. Your dedication has helped shape the future of countless student scientists, and we’re dee...
abrcms.org
August 21, 2025 at 2:48 AM
Join me in donating to ABRCMS. For many of us early in our careers (and for many of us now), this is THE conference. Let’s make sure future generations get the same experience.
I was told if each poster judge donated $25, their goal would be quickly met, but I think we can do better! 🙏🏾💪🏾
I was told if each poster judge donated $25, their goal would be quickly met, but I think we can do better! 🙏🏾💪🏾
Reposted by José Delgado, Ph.D.
Quite a week for #lipidtime: phenomenal study using bifunctional lipid probes to quantify intracellular lipid transport from @nadlerlab.bsky.social and colleagues is now out @nature.com! www.nature.com/articles/s41...
Quantitative imaging of lipid transport in mammalian cells - Nature
Directional, non-vesicular lipid transport is responsible for fast, species-selective lipid sorting into organelle membranes.
www.nature.com
August 20, 2025 at 10:01 PM
Quite a week for #lipidtime: phenomenal study using bifunctional lipid probes to quantify intracellular lipid transport from @nadlerlab.bsky.social and colleagues is now out @nature.com! www.nature.com/articles/s41...
Reposted by José Delgado, Ph.D.
📣 Are you a undergraduate student, graduate student, or early-career professional in the biomedical sciences looking to transition from academia into industry?
Join us for: Thriving in Biotech – Building Bridges, Breaking Barriers.
www.scientistsinsolidarity.org/conference
Join us for: Thriving in Biotech – Building Bridges, Breaking Barriers.
www.scientistsinsolidarity.org/conference
Conference — Scientists in Solidarity
www.scientistsinsolidarity.org
August 20, 2025 at 2:08 AM
📣 Are you a undergraduate student, graduate student, or early-career professional in the biomedical sciences looking to transition from academia into industry?
Join us for: Thriving in Biotech – Building Bridges, Breaking Barriers.
www.scientistsinsolidarity.org/conference
Join us for: Thriving in Biotech – Building Bridges, Breaking Barriers.
www.scientistsinsolidarity.org/conference
Reposted by José Delgado, Ph.D.
🎓 Planning to apply to STEM graduate programs?
Join us for our webinar: “Applying to Grad Programs in STEM” on Thursday, 8/28 at 5.30pm ET.
Gain key insights on:
✅ Grad school application timeline
✅ How to choose the right program
🔗 Register: eventbrite.com/e/gsmi-2025-...
Join us for our webinar: “Applying to Grad Programs in STEM” on Thursday, 8/28 at 5.30pm ET.
Gain key insights on:
✅ Grad school application timeline
✅ How to choose the right program
🔗 Register: eventbrite.com/e/gsmi-2025-...
August 17, 2025 at 9:43 PM
🎓 Planning to apply to STEM graduate programs?
Join us for our webinar: “Applying to Grad Programs in STEM” on Thursday, 8/28 at 5.30pm ET.
Gain key insights on:
✅ Grad school application timeline
✅ How to choose the right program
🔗 Register: eventbrite.com/e/gsmi-2025-...
Join us for our webinar: “Applying to Grad Programs in STEM” on Thursday, 8/28 at 5.30pm ET.
Gain key insights on:
✅ Grad school application timeline
✅ How to choose the right program
🔗 Register: eventbrite.com/e/gsmi-2025-...
New work out of the Pernas Lab!! Congratulations to my lab mates, especially Tania for spearheading this great story!! 🎉
Mitochondria protect against an intracellular pathogen by restricting access to folate | Science www.science.org/doi/10.1126/...
Mitochondria protect against an intracellular pathogen by restricting access to folate | Science www.science.org/doi/10.1126/...
Mitochondria protect against an intracellular pathogen by restricting access to folate
As major consumers of cellular metabolites, mitochondria are poised to compete with invading microbes for the nutrients that they need to grow. Whether cells exploit mitochondrial metabolism to protec...
www.science.org
August 14, 2025 at 6:22 PM
New work out of the Pernas Lab!! Congratulations to my lab mates, especially Tania for spearheading this great story!! 🎉
Mitochondria protect against an intracellular pathogen by restricting access to folate | Science www.science.org/doi/10.1126/...
Mitochondria protect against an intracellular pathogen by restricting access to folate | Science www.science.org/doi/10.1126/...
Great perspective piece out of my PhD lab! 👇🏽
The rapidly expanding role of LC3-interacting regions in #autophagy. New Perspective from Brian North, @doroteaartscience.bsky.social, Christopher Shoemaker and colleagues (Geisel School of Medicine, Dartmouth College): rupress.org/jcb/article/...
August 10, 2025 at 4:55 PM
Great perspective piece out of my PhD lab! 👇🏽
Reposted by José Delgado, Ph.D.
RNA N-glycosylation enables immune evasion and homeostatic efferocytosis by chemically caging acp3U. Excited to report this work lead by Vinnie @vinnieviruses.bsky.social and in collaboration with @vijayrathinam.bsky.social in @nature.com www.nature.com/articles/s41...
August 6, 2025 at 3:36 PM
RNA N-glycosylation enables immune evasion and homeostatic efferocytosis by chemically caging acp3U. Excited to report this work lead by Vinnie @vinnieviruses.bsky.social and in collaboration with @vijayrathinam.bsky.social in @nature.com www.nature.com/articles/s41...
Reposted by José Delgado, Ph.D.
A story from LAist (local LA public radio) about the freezing of funds. I have had my grant frozen, so has nearly everyone else i know. laist.com/news/climate...
UCLA tells researchers to 'immediately stop spending' after Trump administration freezes grant funds
The Trump administration cited alleged antisemitism at UCLA as a reason for suspending the funding. Years worth of research could be lost, one UCLA researcher said.
laist.com
August 2, 2025 at 9:58 PM
A story from LAist (local LA public radio) about the freezing of funds. I have had my grant frozen, so has nearly everyone else i know. laist.com/news/climate...
Reposted by José Delgado, Ph.D.
If you're a UCLA researcher (PI, grad student, etc) with an NSF, NIH or other suddenly suspended grant, please email or DM me.
I'm trying to confirm what the suspension letters say and how extensive the NIH suspensions are.
Email: Mikhail at calmatters dot org
I'm trying to confirm what the suspension letters say and how extensive the NIH suspensions are.
Email: Mikhail at calmatters dot org
I chased this all day:
UCLA research grants suspended after Trump administration faulted campus for antisemitism
calmatters.org/education/hi...
UCLA research grants suspended after Trump administration faulted campus for antisemitism
calmatters.org/education/hi...
UCLA research grants suspended after Trump administration faulted campus for antisemitism
The Justice Department issued UCLA a notice of violation for not responding “adequately” to complaints about antisemitism.
calmatters.org
August 1, 2025 at 3:35 PM
If you're a UCLA researcher (PI, grad student, etc) with an NSF, NIH or other suddenly suspended grant, please email or DM me.
I'm trying to confirm what the suspension letters say and how extensive the NIH suspensions are.
Email: Mikhail at calmatters dot org
I'm trying to confirm what the suspension letters say and how extensive the NIH suspensions are.
Email: Mikhail at calmatters dot org
Reposted by José Delgado, Ph.D.
Multiple federal agencies are suspending research funding at UCLA over allegations it didn’t properly deal with antisemitism on campus. scim.ag/4lbLAcx
NSF and NIH suspend grants to UCLA
Move follows Trump administration finding that school didn’t effectively combat antisemitism
scim.ag
August 1, 2025 at 6:13 PM
Multiple federal agencies are suspending research funding at UCLA over allegations it didn’t properly deal with antisemitism on campus. scim.ag/4lbLAcx
Reposted by José Delgado, Ph.D.
The NSF grants suspended at UCLA total $179M, half of which was still outstanding: CAREER grants, a major math institute, and basic science research and training of all types.
More at grant-witness.us/posts/UCLA-n..., thanks to GW member Mally Shan, with grant-level details in our database.
More at grant-witness.us/posts/UCLA-n..., thanks to GW member Mally Shan, with grant-level details in our database.
August 1, 2025 at 10:04 AM
The NSF grants suspended at UCLA total $179M, half of which was still outstanding: CAREER grants, a major math institute, and basic science research and training of all types.
More at grant-witness.us/posts/UCLA-n..., thanks to GW member Mally Shan, with grant-level details in our database.
More at grant-witness.us/posts/UCLA-n..., thanks to GW member Mally Shan, with grant-level details in our database.
Reposted by José Delgado, Ph.D.
As Requested - A Starter Pack of PIs in Biology (or adjacent) fields who are recruiting POSTDOCS! Please don't hesitate to reach out if you wish to be added! go.bsky.app/4gbXXR3
July 18, 2025 at 6:33 PM
As Requested - A Starter Pack of PIs in Biology (or adjacent) fields who are recruiting POSTDOCS! Please don't hesitate to reach out if you wish to be added! go.bsky.app/4gbXXR3
Reposted by José Delgado, Ph.D.
We are excited to have our new paper out: Tethering of the pathogen sensor caspase-4 to the endomembrane damage sensor galectin-8 poises the host to rapidly detect pathogens that breach the endolysosomal network.
www.cell.com/cell-reports... #innate_immunity #inflammasome #celldeath #immunoSky 1/2
www.cell.com/cell-reports... #innate_immunity #inflammasome #celldeath #immunoSky 1/2
Endolysosomal damage surveillance enables rapid inflammasome sensing of pathogens
Shivcharan et al. report that endosomal damage sensing by the danger receptor galectin-8
licenses noncanonical inflammasome activation and pyroptosis during intracellular
bacterial infections in human...
www.cell.com
July 17, 2025 at 12:12 PM
We are excited to have our new paper out: Tethering of the pathogen sensor caspase-4 to the endomembrane damage sensor galectin-8 poises the host to rapidly detect pathogens that breach the endolysosomal network.
www.cell.com/cell-reports... #innate_immunity #inflammasome #celldeath #immunoSky 1/2
www.cell.com/cell-reports... #innate_immunity #inflammasome #celldeath #immunoSky 1/2
Reposted by José Delgado, Ph.D.
NEW ISSUE! Discussing skeletal muscle adaptations and post-exertional malaise in long COVID, miRNAS in beta cell inflammation, mitochondria as pathogen sensors, lipid droplets in skeletal muscle metabolism, modulating ferroptosis against cancer and much more! (1/2)
www.cell.com/issue/S1043-...
www.cell.com/issue/S1043-...
July 9, 2025 at 7:18 AM
NEW ISSUE! Discussing skeletal muscle adaptations and post-exertional malaise in long COVID, miRNAS in beta cell inflammation, mitochondria as pathogen sensors, lipid droplets in skeletal muscle metabolism, modulating ferroptosis against cancer and much more! (1/2)
www.cell.com/issue/S1043-...
www.cell.com/issue/S1043-...
Reposted by José Delgado, Ph.D.
BWF is proud to announce the 2025 recipients of its Postdoctoral Diversity Enrichment Program (PDEP), which provides critical support to postdoctoral researchers pursuing careers in biomedical and medical research. www.bwfund.org/news/bwf-ann... #bwfpdep
BWF Announces 2025 Postdoctoral Diversity Enrichment Program Recipients - Burroughs Wellcome Fund
Research Triangle Park, N.C. — The Burroughs Wellcome Fund (BWF) is proud to announce the 2025 recipients of its Postdoctoral Diversity Enrichment Program (PDEP), which provides critical support to…
www.bwfund.org
July 9, 2025 at 4:20 PM
BWF is proud to announce the 2025 recipients of its Postdoctoral Diversity Enrichment Program (PDEP), which provides critical support to postdoctoral researchers pursuing careers in biomedical and medical research. www.bwfund.org/news/bwf-ann... #bwfpdep
Reposted by José Delgado, Ph.D.
How innate immunity starts? Early embryos eliminate bacterial infections by epithelial phagocytosis, a conserved process from zebrafish to human embryos. Check our story:
www.cell.com/cell-host-mi...
www.cell.com/cell-host-mi...
June 18, 2025 at 5:11 PM
How innate immunity starts? Early embryos eliminate bacterial infections by epithelial phagocytosis, a conserved process from zebrafish to human embryos. Check our story:
www.cell.com/cell-host-mi...
www.cell.com/cell-host-mi...