Jia-Hou (JH) Poh
jiahou-poh.bsky.social
Jia-Hou (JH) Poh
@jiahou-poh.bsky.social
Research Asst Professor, National University of Singapore, Yong Loo Lin School of Medicine.

Cognitive neuroscientist curious about Motivation and Memory.

https://poh-brainmemlab.github.io/BrainMemLab/
Pinned
How does motivation shape learning and memory? In a new review w @ralisonadcock.bsky.social, we propose that under different motivational ‘moods', neuromodulators set distinct neural contexts to determine information processing and memory formation.
doi.org/10.1146/annu...
#psychscisky #neuroskyence
Motivation as Neural Context for Adaptive Learning and Memory Formation
Our memories shape our perception of the world and guide adaptive behavior. Rather than a veridical record of experiences, memory is selective. An accumulating body of work suggests that motivational ...
www.annualreviews.org
Reposted by Jia-Hou (JH) Poh
Very cool new work from the Iglesias group at MGH: A probabilistic histological atlas of the human brain for MRI segmentation (also available at OpenNeuro - openneuro.org/datasets/ds0...) : www.nature.com/articles/s41...
A probabilistic histological atlas of the human brain for MRI segmentation - Nature
NextBrain is an open source, probabilistic atlas of the entire human brain, assembled using artificial-intelligence-enabled registration and segmentation methods to reconstruct the multimodal serial h...
www.nature.com
November 21, 2025 at 3:32 PM
Reposted by Jia-Hou (JH) Poh
My paper is out!
Computational modeling of error patterns during reward-based learning show evidence that habit learning (value free!) supplements working memory in 7 human data sets.
rdcu.be/eQjLN
A habit and working memory model as an alternative account of human reward-based learning
Nature Human Behaviour - In this study, Collins proposes an alternative dual-process (working memory and habit) model of reinforcement learning in humans.
rdcu.be
November 17, 2025 at 5:18 PM
Reposted by Jia-Hou (JH) Poh
New paper from our lab by Ricardo Morales-Torres (@rmt93.bsky.social) on the visual and semantic properties that shape the vividness of mental representations for events past.

psycnet.apa.org/record/2026-...

The short answer to the title, "What Makes Memories Vivid?" is ... meaning!
November 10, 2025 at 3:51 PM
Reposted by Jia-Hou (JH) Poh
Good news everyone: #Duke Summer Seminars in Neuroscience and Philosophy (SSNAP) are back!! We are now accepting applications for SSNAP 2026, which will take place from May 26 to June 6, 2026. #neuroscience #philosophy #brain Please spread the word! ssnap.submittable.com/submit
SSNAP Applications Manager
SSNAP Applications Manager Powered By Submittable - Accept and Curate Digital Content
ssnap.submittable.com
November 7, 2025 at 11:58 AM
Reposted by Jia-Hou (JH) Poh
New issue of Nature - with NINE studies on #brain #development from the BRAIN Initiative Cell Atlas Network (BICAN) 🧠🧪🔬

An amazing set of resources for all scientists working on the brain!

🧠 Immersive feature:
www.nature.com/immersive/d4...

🧠 Perspective:
www.nature.com/articles/s41...
November 5, 2025 at 6:53 PM
Reposted by Jia-Hou (JH) Poh
Alright, let my first action on this platform be to share our new paper.

"Sleep Reactivity Amplifies the Impact of Pre-Sleep Cognitive Arousal on Sleep Disturbances"

Led by Noof Shaif /w Ju Lynn Ong, Julian Lim, Anthony Reffi, and Michael Chee
onlinelibrary.wiley.com/doi/full/10....
<em>Journal of Sleep Research</em> | ESRS Journal | Wiley Online Library
This study investigates how sleep reactivity moderates the ‘stress-pre-sleep arousal-sleep’ pathway in university students. At the within-individual level, both high and low sleep-reactive groups sho...
onlinelibrary.wiley.com
November 3, 2025 at 11:40 PM
Reposted by Jia-Hou (JH) Poh
I wrote a thing on episodic memory and systems consolidation. I hope you all enjoy it and/or find it interesting.

A neural state space for episodic memories

www.sciencedirect.com/science/arti...

#neuroskyence #psychscisky #cognition 🧪
A neural state space for episodic memories
Episodic memories are highly dynamic and change in nonlinear ways over time. This dynamism is not captured by existing systems consolidation theories …
www.sciencedirect.com
November 3, 2025 at 12:56 PM
Reposted by Jia-Hou (JH) Poh
If you missed this event and you want to catch the replay, videos are up at this link:
www.nationalacademies.org/en/event/451...

See this thread for Day 1 highlights, and the next post for Day 2.
Today and tomorrow 11a-3p EST, I'll be live posting this terrific workshop. It's open to all! So register at this link if you'd like to watch too (or follow this 🧵 for the highlights).

Agenda: 16 presentations + overviews, discussions, recaps and reviews.

www.nationalacademies.org/en/event/451...
November 1, 2025 at 3:19 PM
Reposted by Jia-Hou (JH) Poh
We've just launched the first large, site-less (home, direct to participant) randomized trial for treatment of #LongCovid, testing tirzepatide (a GLP-1 drug) vs placebo. Please help spread the word
www.scripps.edu/news-and-eve...
Scripps Research scientists launch new digital clinical trial to test repurposed drug for long COVID symptom relief
www.scripps.edu
October 31, 2025 at 5:07 PM
Reposted by Jia-Hou (JH) Poh
Our experience of time is powerfully shaped by boundaries between events (i.e., going from one meeting to the next). But what about time *within an event*? In new work, we find reliable distortions of time based on internal event structure (e.g., beginnings, middles, and ends)! tinyurl.com/n8mn2sn7
Unfolding event structure distorts subjective time
Our experience of time is often distorted in striking ways. Although prior work has shown that boundaries between events can shape temporal perception…
www.sciencedirect.com
October 29, 2025 at 2:40 PM
Reposted by Jia-Hou (JH) Poh
My co-authors have yet to move to Bluesky, so I'm pleased to announce our latest work has just been published in @nature.com Neuroscience. Amazing work led by Junheng Li, revealing that falling asleep follows a predictable bifurcation pattern #neuroskyence #sleep
www.nature.com/articles/s41...
Falling asleep follows a predictable bifurcation dynamic - Nature Neuroscience
Li et al. propose a conceptual framework to study the phenomenon of falling asleep based on electroencephalogram data. They show that a tipping point marks the brain’s nonlinear wake-to-sleep transiti...
www.nature.com
October 28, 2025 at 5:35 PM
Reposted by Jia-Hou (JH) Poh
I will be recruiting 🌟PhD students🌟 for my newish lab! If you're interested in learning & memory mechanisms applied to individual, interactive & collective behavior using computational modeling, real-world experiments and fMRI, email me! RTs much appreciated 🙏 rouhanilab.com
Interactive Cognition Lab | USC
Interactive Cognition Lab at USC, led by principal investigator, Dr. Nina Rouhani.
rouhanilab.com
October 24, 2025 at 4:57 PM
Reposted by Jia-Hou (JH) Poh
I’m excited to share my recent preprint on a neural network model of free recall that learns multiple memory strategies including the memory palace!

www.biorxiv.org/content/10.1...
October 21, 2025 at 3:36 AM
Reposted by Jia-Hou (JH) Poh
Can AI simulations of human research participants advance cognitive science? In @cp-trendscognsci.bsky.social, @lmesseri.bsky.social & I analyze this vision. We show how “AI Surrogates” entrench practices that limit the generalizability of cognitive science while aspiring to do the opposite. 1/
AI Surrogates and illusions of generalizability in cognitive science
Recent advances in artificial intelligence (AI) have generated enthusiasm for using AI simulations of human research participants to generate new know…
www.sciencedirect.com
October 21, 2025 at 8:24 PM
Reposted by Jia-Hou (JH) Poh
Thrilled to share our new preprint highlighting distinct neurocomputational mechanisms underlying how reward and punishment determine adaptive cognitive control - a massive fMRI study and collaborative team effort with the @shenhavlab.bsky.social 🧠

Link here:
www.biorxiv.org/content/10.1...
Neurocomputational mechanisms underlying the distinct motivational influences of reward and punishment on cognitive control
Human motivation is fundamentally shaped by one's expectations of the reward they could earn for good performance or the punishment they would avoid for poor performance. However, the extent to which ...
www.biorxiv.org
October 20, 2025 at 6:42 PM
Reposted by Jia-Hou (JH) Poh
Set to run for 25 years, the effort will produce multiomic maps not just for monkeys but for developing, adult, aging, and diseased human brains from diverse populations. https://scim.ag/4o44CDP
China launches ambitious collaboration to map primate brains—including ours
25-year plan will tap brain-mapping prowess in two dozen countries to visualize the organ in unprecedented detail
scim.ag
October 19, 2025 at 6:43 PM
Reposted by Jia-Hou (JH) Poh
💓 Biofeedback helps reduce addiction cravings

A trial of 115 adults found that heart rate variability biofeedback cut cravings, negative mood, and substance use by over 60%, supporting recovery efforts.

🔗 doi.org/10.1001/jama...

#Addiction #Recovery #SciComm 🧪
Heart Rate Variability Biofeedback for Substance Use Disorder
This randomized clinical trial evaluates the effects of second-generation heart rate variability biofeedback on negative affect, positive affect, craving, and alcohol and other drug use in adults with...
doi.org
October 16, 2025 at 10:32 AM
Reposted by Jia-Hou (JH) Poh
Coming up on October 28! Dr. Allie Sinclair @asinclair.bsky.social (UPenn/Rice) will be presenting in @motcogmeet.bsky.social series: "Motivational States Bias Choices, Information Consumption, and Memory" 1/
October 16, 2025 at 6:18 PM
Reposted by Jia-Hou (JH) Poh
One of the papers I've been most excited about since starting the lab!

We adopt a network neuroscience approach to understand how arousal reconfigures large-scale functional network organization to support memory of complex narratives!
Out now in @nathumbehav.nature.com! We applied graph theoretic analyses to fMRI data of participants watching movies/listening to stories. Integration across large-scale functional networks mediates arousal-dependent enhancement of narrative memories. Open access link: rdcu.be/eKKAw
October 13, 2025 at 6:35 PM
Reposted by Jia-Hou (JH) Poh
Motivations are like emotions about (what we know about) possible outcomes. Sometimes incentives spur urgency to act, other times to comprehend. Neuromodulatory systems reflect these motivational moods and shape memories. Out now w @jiahou-poh.bsky.social!
www.annualreviews.org/content/jour...
Motivation as Neural Context for Adaptive Learning and Memory Formation
Our memories shape our perception of the world and guide adaptive behavior. Rather than a veridical record of experiences, memory is selective. An accumulating body of work suggests that motivational ...
www.annualreviews.org
October 13, 2025 at 4:39 AM
How does motivation shape learning and memory? In a new review w @ralisonadcock.bsky.social, we propose that under different motivational ‘moods', neuromodulators set distinct neural contexts to determine information processing and memory formation.
doi.org/10.1146/annu...
#psychscisky #neuroskyence
Motivation as Neural Context for Adaptive Learning and Memory Formation
Our memories shape our perception of the world and guide adaptive behavior. Rather than a veridical record of experiences, memory is selective. An accumulating body of work suggests that motivational ...
www.annualreviews.org
October 13, 2025 at 4:09 AM
Reposted by Jia-Hou (JH) Poh
🚨 New paper in Nature Methods:
HippoMaps: multiscale cartography of the human hippocampus

Open-source tools & data to explore structure and function of the 🍤🧠 (histology, in/ex vivo MRI, iEEG)

Led by @jordandekraker.bsky.social

docs: hippomaps.readthedocs.io
paper: doi.org/10.1038/s415...
October 2, 2025 at 11:50 AM
Reposted by Jia-Hou (JH) Poh
New paper from the lab led by Ali Golbabaei. If you’re interested in systems consolidation, generalization and hippocampal neurogenesis a short 🧵 follows:

authors.elsevier.com/a/1lsO73QW8S...
authors.elsevier.com
October 1, 2025 at 12:39 AM
Reposted by Jia-Hou (JH) Poh
1/8
How can the brain create countless unique memories using a single, universal metric of space? We’ve been waiting for the answer to this for two decades!
Read it here:
www.biorxiv.org/content/10.1...
September 25, 2025 at 4:15 AM
Hello world!
Only a year late, but I am now at the NUS Centre for Sleep and Cognition, where I will be directing the Dynamic Brain & Memory lab!
September 15, 2025 at 7:05 AM