Jacques Fattaccioli
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jfattaccioli.bsky.social
Jacques Fattaccioli
@jfattaccioli.bsky.social
Microfluidics • Soft matter • Cells
Ass. Pr. at Sorbonne U. / ENS-PSL and IPGG
Maker of chips, droplets, and tools for curious biology.
Homepage : https://fattaccioli.github.io
Pinned
Each particle carries pH-responsive BODIPY dyes on its surface and a stable reference probe in the core, enabling ratiometric readouts. By decorating the membrane with Fcγ-binding ligands, we drive controlled uptake and capture the earliest steps of phagosome formation.
We introduce a modular biosensing strategy using targeted lipid microparticles to monitor phagosomal acidification in real time. These biomimetic particles are engineered to couple receptor-specific uptake with fluorescence-based pH reporting in macrophages.

www.biorxiv.org/content/10.1...
November 20, 2025 at 5:17 PM
We introduce a microfluidic device that can trap, analyze, and release individual microparticles on demand using membrane deformation driven by pneumatic pressure. The setup uses a deformable membrane suspended over an array of traps.

www.sciencedirect.com/science/arti...
Fully integrated automatic microfluidic setup for immobilization, analysis and non-selective release of particles
We present a microfluidic device that enables trapping, analysis and on-demand release of individual microparticles using membrane deformation induced…
www.sciencedirect.com
November 20, 2025 at 5:02 PM
Reposted by Jacques Fattaccioli
Our work on hydrodynamic instabilities in active jets is on the cover of PRL this week!
journals.aps.org/prl/abstract...

A dialogue between experiment and theory, where we use light to control active suspensions and show how they can be destabilized by their self-generated flows
Pure Hydrodynamic Instabilities in Active Jets of Puller Microalgae
Using phototaxis to control cell orientation, various instabilities can be induced in jets of motile microalgae.
journals.aps.org
November 11, 2025 at 9:43 AM
Reposted by Jacques Fattaccioli
#FDS2025 : @institutcochin.bsky.social a reçu dans ses laboratoires, 140 collégiens et lycéens.
11 équipes de recherche ou plateformes technologiques ont fait découvrir aux élèves la démarche scientifique et la recherche biomédicale.
@cnrsbiologie.bsky.social
@inserm.fr
@upcite.bsky.social
October 10, 2025 at 5:14 PM
Reposted by Jacques Fattaccioli
Thank you @cellmech2025.bsky.social for the invitation, great science, great people, great community!
What an interesting talk!! Thank you so much, @memilieterret.bsky.social!
#cellmech2025
October 3, 2025 at 2:52 PM
A nice sky viewing night with family and kids, thanks to the Space Bus, in Corsica and under the full moon.

Discovered these new (?) smart telescopes providing easy imaging of celestial bodies for a reasonable price
August 9, 2025 at 7:23 AM
Reposted by Jacques Fattaccioli
First post in the Bsky-sphere! You’ll find info about my scientific activity, the DyCRIC team bit.ly/4lgSHk8, and @institutcochin.bsky.social !
August 8, 2025 at 12:33 PM
Reposted by Jacques Fattaccioli
A condensate-based approach reversibly sequesters lipid droplets (LDs) in cells, temporarily halting their functions and enabling detailed study of LD biology and the interactions of LDs with other cellular structures

www.nature.com/articles/s41...
Controlling lipid droplet dynamics via tether condensates - Nature Chemical Biology
Amari et al. developed a condensate-based approach, named ControLD, for reversible trapping and release of lipid droplets inside living cells, temporarily halting their functions, enabling detailed st...
www.nature.com
May 21, 2025 at 5:11 PM
Reposted by Jacques Fattaccioli
What if we could trap Lipid Droplets and control their dynamics in cells?
Our latest work does just that, using Engineered Condensates to manipulate LD behavior.
Exciting results by Chems Amari and the team!
Great collab with ‪@abdourachidthiam.bsky.social‬
#Organelles #Condensates

rdcu.be/emYpU
May 21, 2025 at 11:10 AM
J'ai deux tickets pour Shed Seven à la Maroquinerie le 2/5/2025. Pour les nostalgiques Britpop des 90's. Revente prix coûtant.
April 28, 2025 at 10:16 AM
Reposted by Jacques Fattaccioli
Portrait d'Alexandre Chargueraud #ESPCIAlum

Doctorant (encadré par @jfattaccioli.bsky.social) et lauréat du prix du public MT180 @sorbonne-universite.fr

www.sorbonne-universite.fr/portraits/al...
Alexandre Chargueraud
www.sorbonne-universite.fr
April 18, 2025 at 10:46 AM
Reposted by Jacques Fattaccioli
Félicitations à Alexandre Chargueraud #ESPCIAlum, lauréat du Prix du Public de la finale de « Ma thèse en 180 secondes » @mt180fr.bsky.social de @sorbonne-universite.fr

www.linkedin.com/posts/alexan...

cc @espciparispsl.bsky.social @jfattaccioli.bsky.social
March 13, 2025 at 12:25 PM
Reposted by Jacques Fattaccioli
C'est parti pour la finale du concours "Ma thèse en 180 secondes" de Sorbonne Université ! 🙌

👉 RDV à partir de 18h en direct sur YouTube pour encourager nos doctorantes et doctorants : www.youtube.com/watch?v=Eqhi...

#MT180 - @mt180fr.bsky.social
March 10, 2025 at 4:07 PM
Reposted by Jacques Fattaccioli
On Feb 11, we celebrate the International Day of Women and Girls in Science.
@institutcochin.bsky.social exhibits gender equality among directions and team leaders and recruits young women with exceptional talent, among them in 2024 Clotilde Cadart:
institutcochin.fr/en/news/inte...
#WomenInScience
February 11, 2025 at 2:33 PM
Reposted by Jacques Fattaccioli
Saviez-vous que de nombreuses plateformes de l'Université PSL sont ouvertes aux industriels ?

1re Journée de l’Innovation en Santé du Pôle PSL Innovation, sur le thème Biothérapies & Bioproduction

19 novembre
9h30-19h30
app.swapcard.com/event/journe...

avec @jfattaccioli.bsky.social #ESPCIAlum
app.swapcard.com
November 17, 2024 at 4:25 PM
September 24, 2023 at 6:42 PM