The Jeremy Chase Crawford Lab
@jcclab.bsky.social
Integrative #biologist focused on translational #immunology, #immunotherapy, host-pathogen interactions, and immunoinformatics at St. Jude Children's Research Hospital https://www.stjude.org/directory/c/jeremy-crawford.html
Pinned
St. Jude Is Hiring | Join Our Mission | St. Jude Careers
Explore job opportunities at St. Jude Children’s Research Hospital. Career opportunities exist in the areas of science, clinical care, operations, and more!
talent.stjude.org
Do you know an experienced immunologist who is interested in studying human #immune development with next-generation methods? My lab is #hiring! Great pay, job stability, and a great place to work! Please share widely talent.stjude.org/careers/jobs...
Reposted by The Jeremy Chase Crawford Lab
Nineteen St. Jude scientists have been named to the 2025 Highly Cited Researchers list, the most from St. Jude since the list began. This distinction identifies those whose publications rank in the top 1% for citations, indicating broad influence. ow.ly/HKIk50XrffV
November 13, 2025 at 5:15 PM
Nineteen St. Jude scientists have been named to the 2025 Highly Cited Researchers list, the most from St. Jude since the list began. This distinction identifies those whose publications rank in the top 1% for citations, indicating broad influence. ow.ly/HKIk50XrffV
Super excited to present some of our newest work at @iuis-online.bsky.social #IUIS2025 in Vienna! Definitely the largest hall I’ve ever presented in.
August 19, 2025 at 8:21 AM
Super excited to present some of our newest work at @iuis-online.bsky.social #IUIS2025 in Vienna! Definitely the largest hall I’ve ever presented in.
David Altshuler from Vertex kicking things off at #AGBT25 with an amazing talk but also an inspiring thought: “I hope that ‘hope’ is something that all of the work presented here can help create.” NIH-funded research is ultimately creating hope for the future, and we can’t forget that.
February 23, 2025 at 10:48 PM
David Altshuler from Vertex kicking things off at #AGBT25 with an amazing talk but also an inspiring thought: “I hope that ‘hope’ is something that all of the work presented here can help create.” NIH-funded research is ultimately creating hope for the future, and we can’t forget that.
The JCC Lab is #hiring experienced bench scientists for work on human immunology and assay development! These are long term, stable positions not subject to the ebb and flow of federal funding. talent.stjude.org/careers/jobs...
St. Jude Is Hiring | Join Our Mission | St. Jude Careers
Explore job opportunities at St. Jude Children’s Research Hospital. Career opportunities exist in the areas of science, clinical care, operations, and more!
talent.stjude.org
February 2, 2025 at 4:58 PM
The JCC Lab is #hiring experienced bench scientists for work on human immunology and assay development! These are long term, stable positions not subject to the ebb and flow of federal funding. talent.stjude.org/careers/jobs...
I have collected Christmas ornaments for years, but two of my close collaborators just gifted me my first JCC Lab ornament! They said it’s a rocket because “the lab is taking off”. Thanks so much @asya-minervina.bsky.social and Misha!
December 31, 2024 at 3:45 AM
I have collected Christmas ornaments for years, but two of my close collaborators just gifted me my first JCC Lab ornament! They said it’s a rocket because “the lab is taking off”. Thanks so much @asya-minervina.bsky.social and Misha!
Had a very productive and eventful time at @niaidnews.bsky.social for the annual meeting on the impact of initial influenza exposure on infant immunity. #immunology #development @eksliger.bsky.social @pgtimmune.bsky.social
December 11, 2024 at 10:15 PM
Had a very productive and eventful time at @niaidnews.bsky.social for the annual meeting on the impact of initial influenza exposure on infant immunity. #immunology #development @eksliger.bsky.social @pgtimmune.bsky.social
Reposted by The Jeremy Chase Crawford Lab
Great interview of Sydney Brenner. One of my favorite stories of Crick and Brenner is their reaction to being scooped by Marshall Nirenberg in deciphering the genetic code. They were thrilled 🧪
December 8, 2024 at 4:10 PM
Great interview of Sydney Brenner. One of my favorite stories of Crick and Brenner is their reaction to being scooped by Marshall Nirenberg in deciphering the genetic code. They were thrilled 🧪
Reposted by The Jeremy Chase Crawford Lab
Excited to share this paper from my post-doc at @niaidnews.bsky.social out now in Science Immunology! We show that recent or ongoing 🫁 infections or other pulmonary environmental exposures at the time of infection with SARSCoV2 can vastly influence early replication of the virus in mice.
The inflammatory microenvironment of the lung at the time of infection governs innate control of SARS-CoV-2 replication
Recent or ongoing respiratory inflammation in the lung regulates antiviral immune responses to SARS-CoV-2.
www.science.org
December 7, 2024 at 11:47 PM
Excited to share this paper from my post-doc at @niaidnews.bsky.social out now in Science Immunology! We show that recent or ongoing 🫁 infections or other pulmonary environmental exposures at the time of infection with SARSCoV2 can vastly influence early replication of the virus in mice.
Super cool work with wide-ranging implications!
Amazing new work from the lab of @aliceyting.bsky.social @stanfordmedicine.bsky.social @stanfordbiosci.bsky.social, engineered GPCRs for ligand-activated cell responses
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Synthetic GPCRs for programmable sensing and control of cell behaviour - Nature
Modular synthetic G-protein-coupled receptors with nanobody-based ligand-recognition domains can be designed and used to programme transgene expression, real-time fluorescence or endogenous G-protein ...
www.nature.com
December 5, 2024 at 3:00 PM
Super cool work with wide-ranging implications!
Reposted by The Jeremy Chase Crawford Lab
very impressed by so many of India’s doctors and scientists stepping up to organize, innovate, and strategically confront the challenge of AMR that threatens their populous country and the world beyond
🇮🇳 🧫 🦠 💊 🇮🇳
www.bbc.com/news/article...
🇮🇳 🧫 🦠 💊 🇮🇳
www.bbc.com/news/article...
India's 'blockbuster' drugs to combat antibiotic-resistant superbugs
A number of promising new drugs from India show potential to fight antibiotic-resistant bacteria.
www.bbc.com
December 5, 2024 at 2:55 PM
very impressed by so many of India’s doctors and scientists stepping up to organize, innovate, and strategically confront the challenge of AMR that threatens their populous country and the world beyond
🇮🇳 🧫 🦠 💊 🇮🇳
www.bbc.com/news/article...
🇮🇳 🧫 🦠 💊 🇮🇳
www.bbc.com/news/article...
Great visit with an amazing talk and lovely dinner with @cobey.bsky.social today! And great company from @pgtimmune.bsky.social @rajerer.bsky.social ! Brilliant!
December 4, 2024 at 2:47 AM
Great visit with an amazing talk and lovely dinner with @cobey.bsky.social today! And great company from @pgtimmune.bsky.social @rajerer.bsky.social ! Brilliant!
Reposted by The Jeremy Chase Crawford Lab
Affinity maturation of antibody responses is mediated by differential plasma cell proliferation
doi.org/10.1101/2024...
doi.org/10.1101/2024...
Affinity maturation of antibody responses is mediated by differential plasma cell proliferation
Increased antibody affinity over time after vaccination, known as affinity maturation, is a prototypical feature of immune responses. Recent studies have shown that a diverse collection of B cells, pr...
doi.org
December 1, 2024 at 2:58 AM
Affinity maturation of antibody responses is mediated by differential plasma cell proliferation
doi.org/10.1101/2024...
doi.org/10.1101/2024...
Reposted by The Jeremy Chase Crawford Lab
We could go on about how we welcome publishers, we don't demote links, we encourage independent developers to build apps and extensions on top of Bluesky's network.... but instead, we'll show you.
All thanks to the incredible community here! 🦋
All thanks to the incredible community here! 🦋
The Engagement Is Better on Bluesky - Bluesky
Bluesky is the lobby to the open web. Find and build your community here.
bsky.social
November 29, 2024 at 10:30 PM
We could go on about how we welcome publishers, we don't demote links, we encourage independent developers to build apps and extensions on top of Bluesky's network.... but instead, we'll show you.
All thanks to the incredible community here! 🦋
All thanks to the incredible community here! 🦋
Reposted by The Jeremy Chase Crawford Lab
How does antiviral #immunity against #influenza evolve across human lifespan? 👶➡️👧➡️👱➡️👵
Our study in Nature Immunology investigates the difference in CD8 T cell response across human lifespan - a🧵⬇️ go.unimelb.edu.au/627s
Katherine Kedzierska, Fabio Luciani, The Doherty Institute
Our study in Nature Immunology investigates the difference in CD8 T cell response across human lifespan - a🧵⬇️ go.unimelb.edu.au/627s
Katherine Kedzierska, Fabio Luciani, The Doherty Institute
November 30, 2024 at 11:10 AM
How does antiviral #immunity against #influenza evolve across human lifespan? 👶➡️👧➡️👱➡️👵
Our study in Nature Immunology investigates the difference in CD8 T cell response across human lifespan - a🧵⬇️ go.unimelb.edu.au/627s
Katherine Kedzierska, Fabio Luciani, The Doherty Institute
Our study in Nature Immunology investigates the difference in CD8 T cell response across human lifespan - a🧵⬇️ go.unimelb.edu.au/627s
Katherine Kedzierska, Fabio Luciani, The Doherty Institute
Reposted by The Jeremy Chase Crawford Lab
A panoramic view of cell population dynamics in mammalian aging www.science.org/doi/10.1126/...
A panoramic view of cell population dynamics in mammalian aging
To elucidate aging-associated cellular population dynamics, we present PanSci, a single-cell transcriptome atlas profiling over 20 million cells from 623 mouse tissues across different life stages, se...
www.science.org
November 29, 2024 at 6:56 AM
A panoramic view of cell population dynamics in mammalian aging www.science.org/doi/10.1126/...
Reposted by The Jeremy Chase Crawford Lab
Design of high specificity binders for peptide-MHC-I complexes https://www.biorxiv.org/content/10.1101/2024.11.28.625793v1
Design of high specificity binders for peptide-MHC-I complexes https://www.biorxiv.org/content/10.1101/2024.11.28.625793v1
Class I MHC molecules present peptides derived from intracellular antigens on the cell surface for i
www.biorxiv.org
November 29, 2024 at 5:15 AM
Design of high specificity binders for peptide-MHC-I complexes https://www.biorxiv.org/content/10.1101/2024.11.28.625793v1
Reposted by The Jeremy Chase Crawford Lab
New publication by @aelewaut.bsky.social & @guillemxtivill.bsky.social from @obenaufa.bsky.social lab about cancer-mediated immune evasion – very interesting!
#HemeSky #OncoSky
www.nature.com/articles/s41...
#HemeSky #OncoSky
www.nature.com/articles/s41...
Cancer cells impair monocyte-mediated T cell stimulation to evade immunity - Nature
Inflammatory monocytes are identified as important players in T cell restimulation in the tumour microenvironment.
www.nature.com
November 28, 2024 at 5:48 PM
New publication by @aelewaut.bsky.social & @guillemxtivill.bsky.social from @obenaufa.bsky.social lab about cancer-mediated immune evasion – very interesting!
#HemeSky #OncoSky
www.nature.com/articles/s41...
#HemeSky #OncoSky
www.nature.com/articles/s41...
Reposted by The Jeremy Chase Crawford Lab
Hi all! I've created a started pack for academic professional development. Looking to build a community of folks supporting researchers, scholars, and educators (broadly defined) by sharing skills, tools, and resources. Please share and reply to nominate yourself or others!
go.bsky.app/vGDioH
go.bsky.app/vGDioH
November 24, 2024 at 3:44 PM
Hi all! I've created a started pack for academic professional development. Looking to build a community of folks supporting researchers, scholars, and educators (broadly defined) by sharing skills, tools, and resources. Please share and reply to nominate yourself or others!
go.bsky.app/vGDioH
go.bsky.app/vGDioH
Reposted by The Jeremy Chase Crawford Lab
Talking of Bier, @orthopodreg.bsky.social the story of how he developed spinal anaesthesia is pretty wild
A story of cocaine, cigars, and German army helmets. #AnSky #MedSky #HistoryMedSky
A story of cocaine, cigars, and German army helmets. #AnSky #MedSky #HistoryMedSky
a baby rhino is playing with snow in a zoo enclosure .
Alt: a baby rhino is playing with snow in a zoo enclosure .
media.tenor.com
November 24, 2024 at 10:29 AM
Talking of Bier, @orthopodreg.bsky.social the story of how he developed spinal anaesthesia is pretty wild
A story of cocaine, cigars, and German army helmets. #AnSky #MedSky #HistoryMedSky
A story of cocaine, cigars, and German army helmets. #AnSky #MedSky #HistoryMedSky
Reposted by The Jeremy Chase Crawford Lab
Hi everyone!
To start on 🦋, we will share what we did during this crazy year!! 🤩🎉
To start, our work on the receptor of #CCHFV 🦠: www.nature.com/articles/s41...
And related to that: our review on lipoproteins receptors used by viruses 🚪: www.jbc.org/article/S002...
To start on 🦋, we will share what we did during this crazy year!! 🤩🎉
To start, our work on the receptor of #CCHFV 🦠: www.nature.com/articles/s41...
And related to that: our review on lipoproteins receptors used by viruses 🚪: www.jbc.org/article/S002...
November 24, 2024 at 11:50 AM
Hi everyone!
To start on 🦋, we will share what we did during this crazy year!! 🤩🎉
To start, our work on the receptor of #CCHFV 🦠: www.nature.com/articles/s41...
And related to that: our review on lipoproteins receptors used by viruses 🚪: www.jbc.org/article/S002...
To start on 🦋, we will share what we did during this crazy year!! 🤩🎉
To start, our work on the receptor of #CCHFV 🦠: www.nature.com/articles/s41...
And related to that: our review on lipoproteins receptors used by viruses 🚪: www.jbc.org/article/S002...
Reposted by The Jeremy Chase Crawford Lab
How well do vaccines protect vs #LongCovid, a systematic review during the Omicron era?
—about 20% reduced by primary series (vs no vaccination), and
—another 20% reduction by boosters vs primary series
www.medrxiv.org/content/10.1...
—about 20% reduced by primary series (vs no vaccination), and
—another 20% reduction by boosters vs primary series
www.medrxiv.org/content/10.1...
November 23, 2024 at 3:33 PM
How well do vaccines protect vs #LongCovid, a systematic review during the Omicron era?
—about 20% reduced by primary series (vs no vaccination), and
—another 20% reduction by boosters vs primary series
www.medrxiv.org/content/10.1...
—about 20% reduced by primary series (vs no vaccination), and
—another 20% reduction by boosters vs primary series
www.medrxiv.org/content/10.1...
Who did I miss? Excited to get more SJ folks on the platform. go.bsky.app/Lv6kNiq
November 20, 2024 at 5:06 PM
Who did I miss? Excited to get more SJ folks on the platform. go.bsky.app/Lv6kNiq
Do you know an experienced immunologist who is interested in studying human #immune development with next-generation methods? My lab is #hiring! Great pay, job stability, and a great place to work! Please share widely talent.stjude.org/careers/jobs...
St. Jude Is Hiring | Join Our Mission | St. Jude Careers
Explore job opportunities at St. Jude Children’s Research Hospital. Career opportunities exist in the areas of science, clinical care, operations, and more!
talent.stjude.org
November 20, 2024 at 5:56 AM
Do you know an experienced immunologist who is interested in studying human #immune development with next-generation methods? My lab is #hiring! Great pay, job stability, and a great place to work! Please share widely talent.stjude.org/careers/jobs...