James Pirruccello 🌉
@jamespirruccello.com
AI slop (except one) enjoyer
Reposted by James Pirruccello 🌉
PSA for people with NIH grant periods starting January 1st (including most NIGMS MIRAs): your RPPR is due Saturday, but they haven’t sent out the usual automated reminders, presumably due to the shutdown
November 11, 2025 at 1:20 AM
PSA for people with NIH grant periods starting January 1st (including most NIGMS MIRAs): your RPPR is due Saturday, but they haven’t sent out the usual automated reminders, presumably due to the shutdown
Act of Claude: something you attempt disclaim liability for because it was entirely vibe coded.
November 10, 2025 at 10:56 PM
Act of Claude: something you attempt disclaim liability for because it was entirely vibe coded.
Reposted by James Pirruccello 🌉
📊 Research Summary from @jama.com: Adults with #AFib who drank at least one cup of caffeinated coffee daily after successful cardioversion had a lower risk of recurrence than those who abstained from coffee and caffeine.
#AHA25 @ahascience.bsky.social
ja.ma/47Nwy8q
#AHA25 @ahascience.bsky.social
ja.ma/47Nwy8q
November 9, 2025 at 3:20 PM
📊 Research Summary from @jama.com: Adults with #AFib who drank at least one cup of caffeinated coffee daily after successful cardioversion had a lower risk of recurrence than those who abstained from coffee and caffeine.
#AHA25 @ahascience.bsky.social
ja.ma/47Nwy8q
#AHA25 @ahascience.bsky.social
ja.ma/47Nwy8q
Soumith Chintala stepping away from PyTorch
soumith.ch
November 7, 2025 at 6:41 AM
Soumith Chintala stepping away from PyTorch
I like how Voalte blocks the entire screen when you have weak internet. Innovative.
November 6, 2025 at 11:41 PM
I like how Voalte blocks the entire screen when you have weak internet. Innovative.
Reposted by James Pirruccello 🌉
DataRater can continuously+adaptively learn which examples will improve an ML model the most during training.
Delighted to have worked on this with @luisazintgraf.bsky.social, @dancalian.bsky.social, @gregfar.bsky.social, Iurii Kemaev, et al. (see full list at the of Luisa's thread).
Delighted to have worked on this with @luisazintgraf.bsky.social, @dancalian.bsky.social, @gregfar.bsky.social, Iurii Kemaev, et al. (see full list at the of Luisa's thread).
Excited to share our new paper, "DataRater: Meta-Learned Dataset Curation"!
We explore a fundamental question: How can we *automatically* learn which data is most valuable for training foundation models?
Paper: arxiv.org/pdf/2505.17895 to appear at @neuripsconf.bsky.social
Thread 👇
We explore a fundamental question: How can we *automatically* learn which data is most valuable for training foundation models?
Paper: arxiv.org/pdf/2505.17895 to appear at @neuripsconf.bsky.social
Thread 👇
November 6, 2025 at 3:43 PM
DataRater can continuously+adaptively learn which examples will improve an ML model the most during training.
Delighted to have worked on this with @luisazintgraf.bsky.social, @dancalian.bsky.social, @gregfar.bsky.social, Iurii Kemaev, et al. (see full list at the of Luisa's thread).
Delighted to have worked on this with @luisazintgraf.bsky.social, @dancalian.bsky.social, @gregfar.bsky.social, Iurii Kemaev, et al. (see full list at the of Luisa's thread).
Thank you to @pelosi.house.gov for your legendary service to our district and Godspeed to @scottwiener.bsky.social
November 6, 2025 at 3:09 PM
Thank you to @pelosi.house.gov for your legendary service to our district and Godspeed to @scottwiener.bsky.social
This IS a place of honor
November 5, 2025 at 2:26 AM
This IS a place of honor
Regression to the kind
November 3, 2025 at 8:11 AM
Regression to the kind
Reposted by James Pirruccello 🌉
Yes, @microsoft.com Outlook, you’re absolutely right: I just typed in my username and password and then invoked my 2FA because I wanted to be logged out!
November 2, 2025 at 4:11 PM
Yes, @microsoft.com Outlook, you’re absolutely right: I just typed in my username and password and then invoked my 2FA because I wanted to be logged out!
For those of you keeping score at home: we were talking about 67 at the American College of Cardiology today. 67 is officially over.
October 30, 2025 at 7:38 PM
For those of you keeping score at home: we were talking about 67 at the American College of Cardiology today. 67 is officially over.
Reposted by James Pirruccello 🌉
I was on a plane with no wifi for 5 hours and we’re doing nukes now???
October 30, 2025 at 2:04 AM
I was on a plane with no wifi for 5 hours and we’re doing nukes now???
Someone needs to invent a cologne/perfume-meter that we can place right after the metal detector at the airport.
October 29, 2025 at 8:38 PM
Someone needs to invent a cologne/perfume-meter that we can place right after the metal detector at the airport.
Why is Grok fact-checking Bundt cake?
October 29, 2025 at 8:21 PM
Why is Grok fact-checking Bundt cake?
This is the most fundamental question that people often fail to ask in papers that I read that involve a cluster analysis.
A: Cluster analysis of X
Q: …uhm…are there distinct clusters of X?
Q: …uhm…are there distinct clusters of X?
October 28, 2025 at 1:30 AM
This is the most fundamental question that people often fail to ask in papers that I read that involve a cluster analysis.
Reposted by James Pirruccello 🌉
this is specifically a problem with the memory feature, which everyone should have anticipated was dangerous.
consider that the psychotic loop of chatgpt mostly seems to be 'the chatbot repeating your own ideas back to you and telling you they're brilliant' and then consider billionaires and the people around them
by OpenAI’s own estimates, hundreds of thousands of ChatGPT users are showing signs of manic or psychotic crisis every week
October 27, 2025 at 5:27 PM
this is specifically a problem with the memory feature, which everyone should have anticipated was dangerous.
Who called it “A House of Dynamite” when “Zeno Dark Thirty” was right there?
October 26, 2025 at 4:40 AM
Who called it “A House of Dynamite” when “Zeno Dark Thirty” was right there?
A House of Dynamite (2025)
a green truck is driving down a road in a field .
ALT: a green truck is driving down a road in a field .
media.tenor.com
October 25, 2025 at 8:16 PM
A House of Dynamite (2025)
Zero dark thirty-one was no good.
October 25, 2025 at 4:00 AM
Zero dark thirty-one was no good.
Reposted by James Pirruccello 🌉
New event at #AHA2025!
GPM Symposium Model Systems: Preclinical to Phase I Bridge
Nov 7 12:30-5:15
Learn state-of-the-art systems to bridge therapies from the Preclinical to Phase I trials
Speakers: Kricket Seidman, Joe Wu, Kiran Musunuru, Vicki Parikh, Eric Adler, and more!
GPM Symposium Model Systems: Preclinical to Phase I Bridge
Nov 7 12:30-5:15
Learn state-of-the-art systems to bridge therapies from the Preclinical to Phase I trials
Speakers: Kricket Seidman, Joe Wu, Kiran Musunuru, Vicki Parikh, Eric Adler, and more!
October 24, 2025 at 9:05 PM
New event at #AHA2025!
GPM Symposium Model Systems: Preclinical to Phase I Bridge
Nov 7 12:30-5:15
Learn state-of-the-art systems to bridge therapies from the Preclinical to Phase I trials
Speakers: Kricket Seidman, Joe Wu, Kiran Musunuru, Vicki Parikh, Eric Adler, and more!
GPM Symposium Model Systems: Preclinical to Phase I Bridge
Nov 7 12:30-5:15
Learn state-of-the-art systems to bridge therapies from the Preclinical to Phase I trials
Speakers: Kricket Seidman, Joe Wu, Kiran Musunuru, Vicki Parikh, Eric Adler, and more!