L
@iknowmyself.bsky.social
Reposted by L
Korea National Institute of Health researchers gave SARS-CoV-2 spike protein to rats and found it entered the brain, disrupted synapses, triggered Alzheimer’s and Parkinson’s-related protein buildup, and impaired memory
Metformin prevented these effects
journals.plos.org/plosone/arti...
Metformin prevented these effects
journals.plos.org/plosone/arti...
SARS-CoV-2 spike protein causes synaptic dysfunction and p-tau and α-synuclein aggregation leading cognitive impairment: The protective role of metformin
Patients recovering from post-coronavirus disease 2019 (COVID-19) often experience cognitive dysfunction, including difficulties with focusing, conversation, or memory issues, which can persist for we...
journals.plos.org
November 9, 2025 at 1:57 PM
Korea National Institute of Health researchers gave SARS-CoV-2 spike protein to rats and found it entered the brain, disrupted synapses, triggered Alzheimer’s and Parkinson’s-related protein buildup, and impaired memory
Metformin prevented these effects
journals.plos.org/plosone/arti...
Metformin prevented these effects
journals.plos.org/plosone/arti...
Reposted by L
Five European hospitals followed 307 patients with B-cell cancers who caught COVID.
At least 26% had infections that lingered.
Anti-CD20 drugs and hospitalization raised the risk, while early antivirals cut it sharply.
www.sciencedirect.com/science/arti...
At least 26% had infections that lingered.
Anti-CD20 drugs and hospitalization raised the risk, while early antivirals cut it sharply.
www.sciencedirect.com/science/arti...
Risk Factors for Persisting SARS-CoV-2 Infection in Patients with B-Cell Malignancies in the Omicron Era: A Multicenter Cohort Study
Patients with B-cell malignancies are at high risk of persisting SARS-CoV-2 infection, which may delay oncologic treatments and increase morbidity. We…
www.sciencedirect.com
September 15, 2025 at 12:03 AM
Five European hospitals followed 307 patients with B-cell cancers who caught COVID.
At least 26% had infections that lingered.
Anti-CD20 drugs and hospitalization raised the risk, while early antivirals cut it sharply.
www.sciencedirect.com/science/arti...
At least 26% had infections that lingered.
Anti-CD20 drugs and hospitalization raised the risk, while early antivirals cut it sharply.
www.sciencedirect.com/science/arti...
Reposted by L
Release from HHS: HHS will wind down its development of the mRNA vaccine development activities under the Biomedical Advanced Research and Development Authority (BARDA).
August 5, 2025 at 10:04 PM
Release from HHS: HHS will wind down its development of the mRNA vaccine development activities under the Biomedical Advanced Research and Development Authority (BARDA).
Reposted by L
Why do elite athletes—who train relentlessly for a mental & physical edge—ignore a virus that literally destroys both?
SARS-CoV-2 impairs cognition, damages the heart, shrinks gray matter, and attacks mitochondria.
So why the denial?
Let’s talk psychology. 🧵
SARS-CoV-2 impairs cognition, damages the heart, shrinks gray matter, and attacks mitochondria.
So why the denial?
Let’s talk psychology. 🧵
July 24, 2025 at 7:29 AM
Why do elite athletes—who train relentlessly for a mental & physical edge—ignore a virus that literally destroys both?
SARS-CoV-2 impairs cognition, damages the heart, shrinks gray matter, and attacks mitochondria.
So why the denial?
Let’s talk psychology. 🧵
SARS-CoV-2 impairs cognition, damages the heart, shrinks gray matter, and attacks mitochondria.
So why the denial?
Let’s talk psychology. 🧵
Reposted by L
China-based researchers enrolled 84 patients with mild COVID-19 and found that inhaled antibody BM219 was safe, well tolerated, and reduced recovery time by over 5 days especially effective against the immune-evasive JN.1 variant.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Inhaled bispecific single-domain antibody BM219 for mild-to-moderate COVID-19: a double-blind, randomized, placebo-controlled phase 2 trial - Cell Discovery
Cell Discovery - Inhaled bispecific single-domain antibody BM219 for mild-to-moderate COVID-19: a double-blind, randomized, placebo-controlled phase 2 trial
www.nature.com
July 17, 2025 at 10:01 PM
China-based researchers enrolled 84 patients with mild COVID-19 and found that inhaled antibody BM219 was safe, well tolerated, and reduced recovery time by over 5 days especially effective against the immune-evasive JN.1 variant.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by L
Egyptian researchers analyzed data from over 4 million people and found that nearly 1 in 3 COVID-19 survivors face long-term cognitive or memory problems, while 43% experience persistent fatigue, revealing a major mental health burden from long COVID.
bmcneurol.biomedcentral.com/articles/10....
bmcneurol.biomedcentral.com/articles/10....
Long-term neurological and cognitive impact of COVID-19: a systematic review and meta-analysis in over 4 million patients - BMC Neurology
Background Neuropsychiatric symptoms emerged early in the COVID-19 pandemic as a key feature of the virus, with research confirming a range of neuropsychiatric manifestations linked to acute SARS-CoV-...
bmcneurol.biomedcentral.com
June 14, 2025 at 10:50 PM
Egyptian researchers analyzed data from over 4 million people and found that nearly 1 in 3 COVID-19 survivors face long-term cognitive or memory problems, while 43% experience persistent fatigue, revealing a major mental health burden from long COVID.
bmcneurol.biomedcentral.com/articles/10....
bmcneurol.biomedcentral.com/articles/10....
Reposted by L
RFK Jr. spouted dangerous vaccine falsehoods on national TV. As a parent and infectious diseases doctor, I couldn't stay silent. Here's what the data actually shows. 🧵
June 13, 2025 at 5:26 AM
RFK Jr. spouted dangerous vaccine falsehoods on national TV. As a parent and infectious diseases doctor, I couldn't stay silent. Here's what the data actually shows. 🧵
Reposted by L
Hamilton researchers studied 76 people including frail older adults and found no signs of T cell immune exhaustion after repeated SARS-CoV-2 mRNA vaccination, even after four doses.
T cells stayed active and functional in all groups.
www.nature.com/articles/s41...
T cells stayed active and functional in all groups.
www.nature.com/articles/s41...
No evidence of immune exhaustion after repeated SARS-CoV-2 vaccination in vulnerable and healthy populations - Nature Communications
Repeated vaccination is needed to maintain high levels of SARS-CoV-2 immunity in vulnerable populations, but there is concern that it could lead to immune exhaustion. Here, the authors assess the evid...
www.nature.com
June 5, 2025 at 11:56 AM
Hamilton researchers studied 76 people including frail older adults and found no signs of T cell immune exhaustion after repeated SARS-CoV-2 mRNA vaccination, even after four doses.
T cells stayed active and functional in all groups.
www.nature.com/articles/s41...
T cells stayed active and functional in all groups.
www.nature.com/articles/s41...
Reposted by L
The harmful effects of cold plunges among young individuals
Even worse among older adults
journals.lww.com/acsm-msse/ab...
gift link wapo.st/4dMyYXk by @gretchenxreynolds.bsky.social
Even worse among older adults
journals.lww.com/acsm-msse/ab...
gift link wapo.st/4dMyYXk by @gretchenxreynolds.bsky.social
June 5, 2025 at 1:28 PM
The harmful effects of cold plunges among young individuals
Even worse among older adults
journals.lww.com/acsm-msse/ab...
gift link wapo.st/4dMyYXk by @gretchenxreynolds.bsky.social
Even worse among older adults
journals.lww.com/acsm-msse/ab...
gift link wapo.st/4dMyYXk by @gretchenxreynolds.bsky.social
Reposted by L
@lauramiers.bsky.social
🧪 The Genetic Link to Abnormal Clotting in Long Covid | With Dr Jordan Vaughn youtu.be/gdTazrFqle8?... via @YouTube
#Microclots
in #LongCovid
-why fibrin breakdown might be key.
off shelf test to discover if you might have a genetic predisposition for microclots in LC.
🧪 The Genetic Link to Abnormal Clotting in Long Covid | With Dr Jordan Vaughn youtu.be/gdTazrFqle8?... via @YouTube
#Microclots
in #LongCovid
-why fibrin breakdown might be key.
off shelf test to discover if you might have a genetic predisposition for microclots in LC.
The Genetic Link to Abnormal Clotting in Long Covid | With Dr Jordan Vaughn
YouTube video by Gez Medinger
youtu.be
February 20, 2025 at 7:36 PM
@lauramiers.bsky.social
🧪 The Genetic Link to Abnormal Clotting in Long Covid | With Dr Jordan Vaughn youtu.be/gdTazrFqle8?... via @YouTube
#Microclots
in #LongCovid
-why fibrin breakdown might be key.
off shelf test to discover if you might have a genetic predisposition for microclots in LC.
🧪 The Genetic Link to Abnormal Clotting in Long Covid | With Dr Jordan Vaughn youtu.be/gdTazrFqle8?... via @YouTube
#Microclots
in #LongCovid
-why fibrin breakdown might be key.
off shelf test to discover if you might have a genetic predisposition for microclots in LC.
Reposted by L
May 28, 2025 at 12:38 AM
Reposted by L
data.wastewaterscan.org still shows what's going around in many communities across the US.
Also, you can bulk order triple COVID/RSV/Flu tests from Europe for less than what a COVID-only costs retail in the US.
Also, you can bulk order triple COVID/RSV/Flu tests from Europe for less than what a COVID-only costs retail in the US.
WastewaterSCAN Dashboard
WastewaterSCAN Data Dashboard tracks infectious diseases across the US via wastewater surveillance.
data.wastewaterscan.org
May 28, 2025 at 7:45 PM
data.wastewaterscan.org still shows what's going around in many communities across the US.
Also, you can bulk order triple COVID/RSV/Flu tests from Europe for less than what a COVID-only costs retail in the US.
Also, you can bulk order triple COVID/RSV/Flu tests from Europe for less than what a COVID-only costs retail in the US.
Reposted by L
Soft launch alert 🚨
I built a tool to help you map your identity over time—from who you are now to who you might become.
It’s free, private, and browser-based. Early testers wanted!
👉 everythingist.com/self-map-app/
🧵👇
I built a tool to help you map your identity over time—from who you are now to who you might become.
It’s free, private, and browser-based. Early testers wanted!
👉 everythingist.com/self-map-app/
🧵👇
Everythingist Self-Space
everythingist.com
May 24, 2025 at 7:35 PM
Soft launch alert 🚨
I built a tool to help you map your identity over time—from who you are now to who you might become.
It’s free, private, and browser-based. Early testers wanted!
👉 everythingist.com/self-map-app/
🧵👇
I built a tool to help you map your identity over time—from who you are now to who you might become.
It’s free, private, and browser-based. Early testers wanted!
👉 everythingist.com/self-map-app/
🧵👇
Reposted by L
Big breakthroughs in Long COVID research are coming this May led by top experts from the NIH, @polybiorf.bsky.social, and teams around the world.
There’s real reason to feel hopeful.
There’s real reason to feel hopeful.
May 6, 2025 at 10:58 PM
Big breakthroughs in Long COVID research are coming this May led by top experts from the NIH, @polybiorf.bsky.social, and teams around the world.
There’s real reason to feel hopeful.
There’s real reason to feel hopeful.
Reposted by L
Belgium-based study of 220 patients found that those with COVID-related smell loss lasting over 6 months reported significantly more depression and anxiety than people without it, especially among women and those with anosmia.
journals.sagepub.com/doi/10.1177/...
journals.sagepub.com/doi/10.1177/...
Psychological Distress in Patients with Long-lasting COVID-19 Olfactory Dysfunction - Manon Louvrier, Sven Saussez, Jerome R. Lechien, 2025
Objective The aim of this study was to investigate the psychological distress associated with long-lasting COVID-19 olfactory dysfunction (OD). Methods Patient...
journals.sagepub.com
May 5, 2025 at 3:24 PM
Belgium-based study of 220 patients found that those with COVID-related smell loss lasting over 6 months reported significantly more depression and anxiety than people without it, especially among women and those with anosmia.
journals.sagepub.com/doi/10.1177/...
journals.sagepub.com/doi/10.1177/...
Reposted by L
Results:
‘These findings indicate that even mild COVID-19 can result in persistent neurocognitive deficits, structural brain alterations, and functional network abnormalities, both in individuals with and without brain fog.’
‘These findings indicate that even mild COVID-19 can result in persistent neurocognitive deficits, structural brain alterations, and functional network abnormalities, both in individuals with and without brain fog.’
May 5, 2025 at 7:57 PM
Results:
‘These findings indicate that even mild COVID-19 can result in persistent neurocognitive deficits, structural brain alterations, and functional network abnormalities, both in individuals with and without brain fog.’
‘These findings indicate that even mild COVID-19 can result in persistent neurocognitive deficits, structural brain alterations, and functional network abnormalities, both in individuals with and without brain fog.’
Reposted by L
Chicago researchers studied 86 mice and found that a high-fiber diet enabled the gut microbiome to fully recover from antibiotics, while a Western-style diet blocked recovery—even after a fecal transplant.
Diet proved more vital than microbes.
www.nature.com/articles/s41...
Diet proved more vital than microbes.
www.nature.com/articles/s41...
Diet outperforms microbial transplant to drive microbiome recovery in mice - Nature
Experiments in mouse models show that proper recovery of the intestinal microbiota following depletion, with or without faecal microbiota transplant therapy, is dependent on syntrophic interactions th...
www.nature.com
April 30, 2025 at 10:40 PM
Chicago researchers studied 86 mice and found that a high-fiber diet enabled the gut microbiome to fully recover from antibiotics, while a Western-style diet blocked recovery—even after a fecal transplant.
Diet proved more vital than microbes.
www.nature.com/articles/s41...
Diet proved more vital than microbes.
www.nature.com/articles/s41...
Reposted by L
Not all #vaccines need a needle.
Professor Chris Chiu's (@cchiu.bsky.social) latest research project—@musiccproject.bsky.social—is testing the potential of nasal and inhaled vaccines against #COVID19 and other viruses.
Read more, this #WorldImmunizationWeek 👉 www.imperial.ac.uk/Stories/the-...
Professor Chris Chiu's (@cchiu.bsky.social) latest research project—@musiccproject.bsky.social—is testing the potential of nasal and inhaled vaccines against #COVID19 and other viruses.
Read more, this #WorldImmunizationWeek 👉 www.imperial.ac.uk/Stories/the-...
April 28, 2025 at 7:33 AM
Not all #vaccines need a needle.
Professor Chris Chiu's (@cchiu.bsky.social) latest research project—@musiccproject.bsky.social—is testing the potential of nasal and inhaled vaccines against #COVID19 and other viruses.
Read more, this #WorldImmunizationWeek 👉 www.imperial.ac.uk/Stories/the-...
Professor Chris Chiu's (@cchiu.bsky.social) latest research project—@musiccproject.bsky.social—is testing the potential of nasal and inhaled vaccines against #COVID19 and other viruses.
Read more, this #WorldImmunizationWeek 👉 www.imperial.ac.uk/Stories/the-...
Reposted by L
“Over at Rocketvax, the company is working on a live-attenuated nasal spray SARS-CoV-2 vaccine, touting the program as showing superior efficacy compared to mRNA COVID-19 vaccines in animal models.” www.fiercebiotech.com/biotech/manu...
Manufacturer fuels Swiss biotech’s next-gen vaccine portfolio in new investment deal
Emergent BioSolutions is investing in Swiss biotech Rocketvax, inking a deal designed to fuel the preclinical company’s R&D. | Emergent BioSolutions is investing in Swiss biotech Rocketvax, inking a d...
www.fiercebiotech.com
March 12, 2025 at 5:32 PM
“Over at Rocketvax, the company is working on a live-attenuated nasal spray SARS-CoV-2 vaccine, touting the program as showing superior efficacy compared to mRNA COVID-19 vaccines in animal models.” www.fiercebiotech.com/biotech/manu...
Reposted by L
For those concerned that current nonsense will slow down oral Covid-19 vaccines in the works that seem to be much better at stopping the spread, the good news is there's a version also being developed in Canada. 🇨🇦
www.news-medical.net/news/2025031...
www.news-medical.net/news/2025031...
Next-generation, inhaled COVID-19 vaccine enters phase-2 clinical trial
Researchers at McMaster University have started a phase-2 clinical trial on a next-generation, inhaled COVID-19 vaccine.
www.news-medical.net
March 12, 2025 at 7:14 PM
For those concerned that current nonsense will slow down oral Covid-19 vaccines in the works that seem to be much better at stopping the spread, the good news is there's a version also being developed in Canada. 🇨🇦
www.news-medical.net/news/2025031...
www.news-medical.net/news/2025031...
Reposted by L
Next generation vaccine: First administration in humans of the LovalTech nasal vaccine against COVID-19.
The MUCOBOOST Phase I & II clinical trial will begin shortly in France.
www.inrae.fr/actualites/p...
The MUCOBOOST Phase I & II clinical trial will begin shortly in France.
www.inrae.fr/actualites/p...
Première administration chez l’Homme du vaccin nasal Lovaltech contre la COVID-19
COMMUNIQUÉ DE PRESSE - Une étape majeure dans le développement du vaccin nasal contre la COVID-19 vient d’être franchie : cinq ans après la pandémie, le CHRU de Tours et l’ANRS – Maladies infectieuses...
www.inrae.fr
April 9, 2025 at 10:54 AM
Next generation vaccine: First administration in humans of the LovalTech nasal vaccine against COVID-19.
The MUCOBOOST Phase I & II clinical trial will begin shortly in France.
www.inrae.fr/actualites/p...
The MUCOBOOST Phase I & II clinical trial will begin shortly in France.
www.inrae.fr/actualites/p...
Reposted by L
—How to prevent chronic inflammation that increases with aging ("inflammaging")?
—Exercise
www.nytimes.com/2025/03/19/w...
gift link
—Exercise
www.nytimes.com/2025/03/19/w...
gift link
Here’s One More Reason to Try to Exercise (Gift Article)
Consistent workouts can be a powerful way to fight chronic inflammation.
www.nytimes.com
March 25, 2025 at 7:48 PM
—How to prevent chronic inflammation that increases with aging ("inflammaging")?
—Exercise
www.nytimes.com/2025/03/19/w...
gift link
—Exercise
www.nytimes.com/2025/03/19/w...
gift link