Holmes Lab
@holmeslab-bhi.bsky.social
The Holmes Lab works to understand the genetic and brain bases of individual differences in network organization across psychiatric illness.
📍Rutgers, Center for Advanced Human Brain Imaging Research
holmeslab.rutgers.edu
📍Rutgers, Center for Advanced Human Brain Imaging Research
holmeslab.rutgers.edu
Reposted by Holmes Lab
Looking for a post-bac RA position focused on the brain bases of affective and psychotic illness?
@holmeslab-bhi.bsky.social is hiring!
@cahbir.bsky.social @rutgersbhi.bsky.social @rutgersu.bsky.social @sobp-org.bsky.social @hitop-system.bsky.social @ohbmofficial.bsky.social
@holmeslab-bhi.bsky.social is hiring!
@cahbir.bsky.social @rutgersbhi.bsky.social @rutgersu.bsky.social @sobp-org.bsky.social @hitop-system.bsky.social @ohbmofficial.bsky.social
November 11, 2025 at 3:48 PM
Looking for a post-bac RA position focused on the brain bases of affective and psychotic illness?
@holmeslab-bhi.bsky.social is hiring!
@cahbir.bsky.social @rutgersbhi.bsky.social @rutgersu.bsky.social @sobp-org.bsky.social @hitop-system.bsky.social @ohbmofficial.bsky.social
@holmeslab-bhi.bsky.social is hiring!
@cahbir.bsky.social @rutgersbhi.bsky.social @rutgersu.bsky.social @sobp-org.bsky.social @hitop-system.bsky.social @ohbmofficial.bsky.social
The Holmes Lab is #hiring a full-time research assistant/predoc! Our work focuses on functional brain networks-- how they change, how they are impacted in psychiatric illness, and much more!
Please rt and reach out if you’re interested 👀
Find out more holmeslab.rutgers.edu
Please rt and reach out if you’re interested 👀
Find out more holmeslab.rutgers.edu
November 11, 2025 at 4:50 PM
The Holmes Lab is #hiring a full-time research assistant/predoc! Our work focuses on functional brain networks-- how they change, how they are impacted in psychiatric illness, and much more!
Please rt and reach out if you’re interested 👀
Find out more holmeslab.rutgers.edu
Please rt and reach out if you’re interested 👀
Find out more holmeslab.rutgers.edu
Holmes Lab + Parkes Lab had a great fall social a few weeks back!! Pottery painting (including an awesome brain-art mug by @ambrains.bsky.social 🧠). Thank you to our awesome mentors @avramholmes.bsky.social and @lindenmp.bsky.social for encouraging these great lab events! 💫
October 7, 2025 at 4:16 PM
Holmes Lab + Parkes Lab had a great fall social a few weeks back!! Pottery painting (including an awesome brain-art mug by @ambrains.bsky.social 🧠). Thank you to our awesome mentors @avramholmes.bsky.social and @lindenmp.bsky.social for encouraging these great lab events! 💫
Reposted by Holmes Lab
The @cahbir.bsky.social and @rutgersbhi.bsky.social are hiring! Multiple open area and open rank faculty jobs, wonderful colleagues, amazing resources, and one of the largest communities of brain science research groups on the planet. Please apply and share widely.
jobs.rutgers.edu/postings/209...
jobs.rutgers.edu/postings/209...
Human Neuroimaging Faculty Positions in Rutgers Brain Health Institute
The Center for Advanced Human Brain Imaging Research (CAHBIR), a component of the Rutgers Brain Health Institute (BHI) on the Busch campus in Piscataway, NJ, is recruiting for two open rank (Assistant...
jobs.rutgers.edu
September 5, 2025 at 7:58 PM
The @cahbir.bsky.social and @rutgersbhi.bsky.social are hiring! Multiple open area and open rank faculty jobs, wonderful colleagues, amazing resources, and one of the largest communities of brain science research groups on the planet. Please apply and share widely.
jobs.rutgers.edu/postings/209...
jobs.rutgers.edu/postings/209...
Reposted by Holmes Lab
Latest
@holmeslab-bhi.bsky.social
preprint. Here, integrating genetic, post-mortem, and diffusion MRI data, Rowena Chin examines the heritability and cellular associates of late-life decline in white matter integrity.
@cahbir.bsky.social @rutgersbhi.bsky.social
www.biorxiv.org/content/10.1...
@holmeslab-bhi.bsky.social
preprint. Here, integrating genetic, post-mortem, and diffusion MRI data, Rowena Chin examines the heritability and cellular associates of late-life decline in white matter integrity.
@cahbir.bsky.social @rutgersbhi.bsky.social
www.biorxiv.org/content/10.1...
The cellular associates of late life changes in white matter microstructure
The microstructural architecture of white matter supporting information flow across local circuits and large-scale networks changes throughout the lifespan. However, the genetic and cellular factors u...
www.biorxiv.org
September 4, 2025 at 7:11 PM
Latest
@holmeslab-bhi.bsky.social
preprint. Here, integrating genetic, post-mortem, and diffusion MRI data, Rowena Chin examines the heritability and cellular associates of late-life decline in white matter integrity.
@cahbir.bsky.social @rutgersbhi.bsky.social
www.biorxiv.org/content/10.1...
@holmeslab-bhi.bsky.social
preprint. Here, integrating genetic, post-mortem, and diffusion MRI data, Rowena Chin examines the heritability and cellular associates of late-life decline in white matter integrity.
@cahbir.bsky.social @rutgersbhi.bsky.social
www.biorxiv.org/content/10.1...
Great write up of the @nature.com study on MRI economics by @bttyeo.bsky.social's research group!
With @avramholmes.bsky.social @sidchop.bsky.social @carrisacocuzza.bsky.social
With @avramholmes.bsky.social @sidchop.bsky.social @carrisacocuzza.bsky.social
When powering fMRI studies, sample size is king, but scan duration can also be a powerful tool, improving phenotypic prediction and cost-efficiency, a new analysis shows
By @claudia-lopez.bsky.social
#neuroskyence
www.thetransmitter.org/fmri/longer-...
By @claudia-lopez.bsky.social
#neuroskyence
www.thetransmitter.org/fmri/longer-...
Longer fMRI brain scans boost reliability—but only to a point
Around 30 minutes of imaging per person seems to be the “sweet spot” for linking functional connectivity differences to traits in an accurate and cost-effective way.
www.thetransmitter.org
August 21, 2025 at 3:07 PM
Great write up of the @nature.com study on MRI economics by @bttyeo.bsky.social's research group!
With @avramholmes.bsky.social @sidchop.bsky.social @carrisacocuzza.bsky.social
With @avramholmes.bsky.social @sidchop.bsky.social @carrisacocuzza.bsky.social
Reposted by Holmes Lab
🚨Thrilled to share our latest work just published in @nature.com where we looked into the optimal fMRI scan time for brain-wide association studies (BWAS) 🧠⏱️! Full thread below👇:
1/11 Excited to share our @Naturestudy led by @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social
AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...
doi.org/10.1038/s415...
AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...
doi.org/10.1038/s415...
July 17, 2025 at 2:22 AM
🚨Thrilled to share our latest work just published in @nature.com where we looked into the optimal fMRI scan time for brain-wide association studies (BWAS) 🧠⏱️! Full thread below👇:
Reposted by Holmes Lab
This new Yeo Lab tool should immediately and permanently replace sample-size-only power calculations for functional MRI.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
July 17, 2025 at 11:16 AM
This new Yeo Lab tool should immediately and permanently replace sample-size-only power calculations for functional MRI.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Holmes Lab
Everyone should try out the Trandiagnostic Connectome Project (TCP) dataset! Openly available on @openneuro.bsky.social
V useful paper by @bttyeo.bsky.social @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social in @nature.com. Scan longer if you want to predict behav using fMRI and save $.
Great use of the TCP data: (pmc.ncbi.nlm.nih.gov/articles/PMC...).
Great use of the TCP data: (pmc.ncbi.nlm.nih.gov/articles/PMC...).
July 17, 2025 at 3:24 AM
Everyone should try out the Trandiagnostic Connectome Project (TCP) dataset! Openly available on @openneuro.bsky.social
Reposted by Holmes Lab
Nature research paper: Longer scans boost prediction and cut costs in brain-wide association studies
go.nature.com/3IME4aA
go.nature.com/3IME4aA
Longer scans boost prediction and cut costs in brain-wide association studies - Nature
Although the number of participants is important for phenotypic prediction accuracy in brain-wide association studies using functional MRI, scanning for at least 30 min offers the greatest cost effectiveness.
go.nature.com
July 17, 2025 at 10:35 AM
Nature research paper: Longer scans boost prediction and cut costs in brain-wide association studies
go.nature.com/3IME4aA
go.nature.com/3IME4aA
Holmes Lab is representing at #OHBM2025! 🧵 Loic
@loiclabache.bsky.social presented in the Language: Anatomy, Networks and Pathology section with his paper on "The molecular and cellular underpinnings of human brain lateralization" 🧠
@loiclabache.bsky.social presented in the Language: Anatomy, Networks and Pathology section with his paper on "The molecular and cellular underpinnings of human brain lateralization" 🧠
June 28, 2025 at 12:00 AM
Holmes Lab is representing at #OHBM2025! 🧵 Loic
@loiclabache.bsky.social presented in the Language: Anatomy, Networks and Pathology section with his paper on "The molecular and cellular underpinnings of human brain lateralization" 🧠
@loiclabache.bsky.social presented in the Language: Anatomy, Networks and Pathology section with his paper on "The molecular and cellular underpinnings of human brain lateralization" 🧠
Reposted by Holmes Lab
Check out our latest open data release. n=240, most with a dsm-5 dx with extensive phenotying (~100 scales/subscale), rest and task functional imaging. See @carrisacocuzza.bsky.social's thread below for deets and links 👇🏾👇🏾👇🏾
🚨 Dataset & Manuscript alert! 🚨 The Transdiagnostic Connectome Project (TCP) manuscript is now available @natureportfolio.nature.com Scientific Data! 🎉
www.nature.com/articles/s41...
🧵1👇
www.nature.com/articles/s41...
🧵1👇
The Transdiagnostic Connectome Project: an open dataset for studying brain-behavior relationships in psychiatry - Scientific Data
Scientific Data - The Transdiagnostic Connectome Project: an open dataset for studying brain-behavior relationships in psychiatry
www.nature.com
June 4, 2025 at 11:45 PM
Check out our latest open data release. n=240, most with a dsm-5 dx with extensive phenotying (~100 scales/subscale), rest and task functional imaging. See @carrisacocuzza.bsky.social's thread below for deets and links 👇🏾👇🏾👇🏾
Reposted by Holmes Lab
Very cool preprint examining how brain networks and cognition co-evolve during development
By @bttyeo.bsky.social @lucinauddin.bsky.social @avramholmes.bsky.social @elvisha.bsky.social & colleagues
🧪🧠
www.biorxiv.org/content/10.1...
By @bttyeo.bsky.social @lucinauddin.bsky.social @avramholmes.bsky.social @elvisha.bsky.social & colleagues
🧪🧠
www.biorxiv.org/content/10.1...
Convergent and divergent brain-cognition relationships during development revealed by cross-sectional and longitudinal analyses in the ABCD Study
How brain networks and cognition co-evolve during development remains poorly understood. Using longitudinal data collected at baseline and Year 2 from 2,949 individuals (ages 8.9-13.5) in the Adolesce...
www.biorxiv.org
June 7, 2025 at 10:35 AM
Very cool preprint examining how brain networks and cognition co-evolve during development
By @bttyeo.bsky.social @lucinauddin.bsky.social @avramholmes.bsky.social @elvisha.bsky.social & colleagues
🧪🧠
www.biorxiv.org/content/10.1...
By @bttyeo.bsky.social @lucinauddin.bsky.social @avramholmes.bsky.social @elvisha.bsky.social & colleagues
🧪🧠
www.biorxiv.org/content/10.1...
Reposted by Holmes Lab
Check out my newest preprint to see the TCP dataset in action! 🤘🧠
Brain network dynamics reflect psychiatric illness status and transdiagnostic symptom profiles across health and disease: www.biorxiv.org/content/10.1...
Brain network dynamics reflect psychiatric illness status and transdiagnostic symptom profiles across health and disease: www.biorxiv.org/content/10.1...
June 4, 2025 at 6:34 PM
Check out my newest preprint to see the TCP dataset in action! 🤘🧠
Brain network dynamics reflect psychiatric illness status and transdiagnostic symptom profiles across health and disease: www.biorxiv.org/content/10.1...
Brain network dynamics reflect psychiatric illness status and transdiagnostic symptom profiles across health and disease: www.biorxiv.org/content/10.1...
If you missed it, our open source 240-person transdiagnostic dataset is now published. Read the data release 👇👇 + find it on:
OpenNeuro: openneuro.org/datasets/ds0...
NDA: nda.nih.gov/study.html?i...
OpenNeuro: openneuro.org/datasets/ds0...
NDA: nda.nih.gov/study.html?i...
Check out our latest open data release. n=240, most with a dsm-5 dx with extensive phenotying (~100 scales/subscale), rest and task functional imaging. See @carrisacocuzza.bsky.social's thread below for deets and links 👇🏾👇🏾👇🏾
🚨 Dataset & Manuscript alert! 🚨 The Transdiagnostic Connectome Project (TCP) manuscript is now available @natureportfolio.nature.com Scientific Data! 🎉
www.nature.com/articles/s41...
🧵1👇
www.nature.com/articles/s41...
🧵1👇
June 10, 2025 at 1:51 PM
If you missed it, our open source 240-person transdiagnostic dataset is now published. Read the data release 👇👇 + find it on:
OpenNeuro: openneuro.org/datasets/ds0...
NDA: nda.nih.gov/study.html?i...
OpenNeuro: openneuro.org/datasets/ds0...
NDA: nda.nih.gov/study.html?i...
Reposted by Holmes Lab
🚨 Dataset & Manuscript alert! 🚨 The Transdiagnostic Connectome Project (TCP) manuscript is now available @natureportfolio.nature.com Scientific Data! 🎉
www.nature.com/articles/s41...
🧵1👇
www.nature.com/articles/s41...
🧵1👇
The Transdiagnostic Connectome Project: an open dataset for studying brain-behavior relationships in psychiatry - Scientific Data
Scientific Data - The Transdiagnostic Connectome Project: an open dataset for studying brain-behavior relationships in psychiatry
www.nature.com
June 4, 2025 at 6:30 PM
🚨 Dataset & Manuscript alert! 🚨 The Transdiagnostic Connectome Project (TCP) manuscript is now available @natureportfolio.nature.com Scientific Data! 🎉
www.nature.com/articles/s41...
🧵1👇
www.nature.com/articles/s41...
🧵1👇
Reposted by Holmes Lab
Our latest @holmeslab-bhi.bsky.social data release is now "live!" Available on NDA and @openneuro.bsky.social and spearheaded by @carrisacocuzza.bsky.social, @sidchop.bsky.social, and Connor Lawhead.
🚨 Dataset & Manuscript alert! 🚨 The Transdiagnostic Connectome Project (TCP) manuscript is now available @natureportfolio.nature.com Scientific Data! 🎉
www.nature.com/articles/s41...
🧵1👇
www.nature.com/articles/s41...
🧵1👇
The Transdiagnostic Connectome Project: an open dataset for studying brain-behavior relationships in psychiatry - Scientific Data
Scientific Data - The Transdiagnostic Connectome Project: an open dataset for studying brain-behavior relationships in psychiatry
www.nature.com
June 4, 2025 at 6:46 PM
Our latest @holmeslab-bhi.bsky.social data release is now "live!" Available on NDA and @openneuro.bsky.social and spearheaded by @carrisacocuzza.bsky.social, @sidchop.bsky.social, and Connor Lawhead.
Reposted by Holmes Lab
Brain network dynamics reflect psychiatric illness status and transdiagnostic symptom profiles across health and disease https://www.biorxiv.org/content/10.1101/2025.05.23.655864v1
May 28, 2025 at 11:15 AM
Brain network dynamics reflect psychiatric illness status and transdiagnostic symptom profiles across health and disease https://www.biorxiv.org/content/10.1101/2025.05.23.655864v1
Reposted by Holmes Lab
New @holmeslab-bhi.bsky.social paper led by @carrisacocuzza.bsky.social. Brain dynamics across task and rest can be used to predict the presence of psychiatric illness (case/control status), diagnostic labels, and multi-dimensional symptom fingerprints. @rutgersbhi.bsky.social @rutgersu.bsky.social
🚨Preprint!🚨 So excited to share my 1st major study as a postdoc at @holmeslab-bhi.bsky.social!🤘
www.biorxiv.org/content/10.1...
Using a transdiagnostic framework, we found that brain network dynamics were able to discriminate individualized psychiatric symptom profiles with high accuracy 🧵1/9👇
www.biorxiv.org/content/10.1...
Using a transdiagnostic framework, we found that brain network dynamics were able to discriminate individualized psychiatric symptom profiles with high accuracy 🧵1/9👇
May 30, 2025 at 7:52 PM
New @holmeslab-bhi.bsky.social paper led by @carrisacocuzza.bsky.social. Brain dynamics across task and rest can be used to predict the presence of psychiatric illness (case/control status), diagnostic labels, and multi-dimensional symptom fingerprints. @rutgersbhi.bsky.social @rutgersu.bsky.social
Check out Carrisa's new paper! An amazing investigation into brain network dynamics across psychiatric symptoms🔥🔥
+ using our new open dataset the Transdiagnostic Connectome Project (TCP) 🔛 openneuro.org/datasets/ds0...
+ using our new open dataset the Transdiagnostic Connectome Project (TCP) 🔛 openneuro.org/datasets/ds0...
June 2, 2025 at 3:41 PM
Check out Carrisa's new paper! An amazing investigation into brain network dynamics across psychiatric symptoms🔥🔥
+ using our new open dataset the Transdiagnostic Connectome Project (TCP) 🔛 openneuro.org/datasets/ds0...
+ using our new open dataset the Transdiagnostic Connectome Project (TCP) 🔛 openneuro.org/datasets/ds0...
Great lab outing to Duke Farms yesterday! Happy spring from the Holmes + Parkes labs 😄 🌸
With @lindenmp.bsky.social @avramholmes.bsky.social @carrisacocuzza.bsky.social @ahmadbeyh.bsky.social @loiclabache.bsky.social (+ Amber Howell & Rachel Cooper)
With @lindenmp.bsky.social @avramholmes.bsky.social @carrisacocuzza.bsky.social @ahmadbeyh.bsky.social @loiclabache.bsky.social (+ Amber Howell & Rachel Cooper)
May 29, 2025 at 5:08 PM
Great lab outing to Duke Farms yesterday! Happy spring from the Holmes + Parkes labs 😄 🌸
With @lindenmp.bsky.social @avramholmes.bsky.social @carrisacocuzza.bsky.social @ahmadbeyh.bsky.social @loiclabache.bsky.social (+ Amber Howell & Rachel Cooper)
With @lindenmp.bsky.social @avramholmes.bsky.social @carrisacocuzza.bsky.social @ahmadbeyh.bsky.social @loiclabache.bsky.social (+ Amber Howell & Rachel Cooper)
Reposted by Holmes Lab
We're searching for a lead Research MRI technologists at @cahbir.bsky.social! Please share and pass along to any/all interested folks.
CAHBIR at Rutgers University is looking for a Lead Research MRI Technologist. CAHBIR is a research-only facility that focuses on neuroimaging, and other MR imaging projects. If you are interested, see the information flier linked, and apply online!
go.rutgers.edu/mri-tech
go.rutgers.edu/mri-tech
May 20, 2025 at 2:40 PM
We're searching for a lead Research MRI technologists at @cahbir.bsky.social! Please share and pass along to any/all interested folks.
Last month Linden Parkes and his team put out an amazing new work! They build on their network control theory model & improved whole-brain structure-function coupling
Check this 🧵 for a summary 🔥
www.biorxiv.org/content/10.1...
Check this 🧵 for a summary 🔥
www.biorxiv.org/content/10.1...
May 24, 2025 at 5:53 PM
Last month Linden Parkes and his team put out an amazing new work! They build on their network control theory model & improved whole-brain structure-function coupling
Check this 🧵 for a summary 🔥
www.biorxiv.org/content/10.1...
Check this 🧵 for a summary 🔥
www.biorxiv.org/content/10.1...
Reposted by Holmes Lab
While the world burns, we cook up a new preprint! doi.org/10.1101/2025...
Biophysical modeling is a key tool to derive mechanistic insights into the brain. These models are governed by biologically meaningful parameters (unlike artificial neural networks), but the dirty secret ... 1/N
Biophysical modeling is a key tool to derive mechanistic insights into the brain. These models are governed by biologically meaningful parameters (unlike artificial neural networks), but the dirty secret ... 1/N
April 11, 2025 at 1:35 AM
While the world burns, we cook up a new preprint! doi.org/10.1101/2025...
Biophysical modeling is a key tool to derive mechanistic insights into the brain. These models are governed by biologically meaningful parameters (unlike artificial neural networks), but the dirty secret ... 1/N
Biophysical modeling is a key tool to derive mechanistic insights into the brain. These models are governed by biologically meaningful parameters (unlike artificial neural networks), but the dirty secret ... 1/N
Newest #preprint from Holmes lab postdoc @loiclabache.bsky.social 🔥
🚨 New #preprint: The molecular and cellular underpinnings of human brain lateralization
🔗 doi.org/10.1101/2025...
🧠 We identify an acetylcholine-norepinephrine axis underlying functional lateralization, along with mitochondrial and cellular correlates. 🧵1/9👇
#neuroskyence
🔗 doi.org/10.1101/2025...
🧠 We identify an acetylcholine-norepinephrine axis underlying functional lateralization, along with mitochondrial and cellular correlates. 🧵1/9👇
#neuroskyence
The molecular and cellular underpinnings of human brain lateralization
Hemispheric specialization is a fundamental characteristic of human brain organization, where most individuals exhibit left-hemisphere dominance for language and right-hemisphere dominance for visuosp...
doi.org
April 15, 2025 at 9:38 PM
Newest #preprint from Holmes lab postdoc @loiclabache.bsky.social 🔥