Habeeb
@habeebrahman.bsky.social
Postdoc at Marquette University. Interested in microbial interactions, biofilms and antimicrobials.
Reposted by Habeeb
New paper: www.sciencedirect.com/science/arti...
Klebs can evolve resistance to Colistin through mgrB mutation or by acquiring the mcr-1 gene. Both routes have similar fitness costs against a bacterial competitor, but mgrB mutations are associated with enhanced virulence.
Klebs can evolve resistance to Colistin through mgrB mutation or by acquiring the mcr-1 gene. Both routes have similar fitness costs against a bacterial competitor, but mgrB mutations are associated with enhanced virulence.
mgrB inactivation confers enhanced pathogenicity and immune evasion over mcr-1 expression in colistin-resistant Klebsiella pneumoniae
Colistin is one of the last treatment options against human infections caused by multi-drug resistant Klebsiella pneumoniae. Colistin resistant K. pne…
www.sciencedirect.com
November 6, 2025 at 12:13 PM
New paper: www.sciencedirect.com/science/arti...
Klebs can evolve resistance to Colistin through mgrB mutation or by acquiring the mcr-1 gene. Both routes have similar fitness costs against a bacterial competitor, but mgrB mutations are associated with enhanced virulence.
Klebs can evolve resistance to Colistin through mgrB mutation or by acquiring the mcr-1 gene. Both routes have similar fitness costs against a bacterial competitor, but mgrB mutations are associated with enhanced virulence.
Reposted by Habeeb
𝘚𝘵𝘳𝘦𝘱𝘵𝘰𝘮𝘺𝘤𝘦𝘴 𝘤𝘰𝘦𝘭𝘪𝘤𝘰𝘭𝘰𝘳 A3(2) produces a so far unknown antibiotic (because no one has looked closer, that is)
#MicroSky
🙏thx for pointing this out @microbingle.bsky.social
#MicroSky
🙏thx for pointing this out @microbingle.bsky.social
![The biosynthesis pathway of methylenomcyin A as discovered in this experiment. The new precursors, especially pre-methylenomycin C lactone, show increased potency against Gram-positive bacterial pathogen compared to the original methylenomycin A. [Greg Challis/University of Warwick]](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:gudh3x7pgeh4uc6eee3zogtr/bafkreihr33z23marin4exrxfb3qg53urlzux22xrm3x6apaja5tdqqpvhu@jpeg)
October 28, 2025 at 7:50 PM
𝘚𝘵𝘳𝘦𝘱𝘵𝘰𝘮𝘺𝘤𝘦𝘴 𝘤𝘰𝘦𝘭𝘪𝘤𝘰𝘭𝘰𝘳 A3(2) produces a so far unknown antibiotic (because no one has looked closer, that is)
#MicroSky
🙏thx for pointing this out @microbingle.bsky.social
#MicroSky
🙏thx for pointing this out @microbingle.bsky.social
Reposted by Habeeb
🎓 #PhDPosition !
🍽️ The impact of innovative food ingredients on the human gut microbiome and health with Dr Fred Warren @starchlab.bsky.social
📅Apply by 2 December
➡️ buff.ly/zaFaqGk
🍽️ The impact of innovative food ingredients on the human gut microbiome and health with Dr Fred Warren @starchlab.bsky.social
📅Apply by 2 December
➡️ buff.ly/zaFaqGk
October 29, 2025 at 8:02 AM
🎓 #PhDPosition !
🍽️ The impact of innovative food ingredients on the human gut microbiome and health with Dr Fred Warren @starchlab.bsky.social
📅Apply by 2 December
➡️ buff.ly/zaFaqGk
🍽️ The impact of innovative food ingredients on the human gut microbiome and health with Dr Fred Warren @starchlab.bsky.social
📅Apply by 2 December
➡️ buff.ly/zaFaqGk
Reposted by Habeeb
PhD position on Regulation and Evolution of Bacterial Multicellularity ( #Streptomyces ) within @spp2389.bsky.social supervised by Natalia Tschowri (Hannover 🇩🇪) and Danny Rozen (Leiden 🇳🇱) with research at both locations
deadline: October 31, 2025
www.uni-hannover.de/en/jobs/id/802
deadline: October 31, 2025
www.uni-hannover.de/en/jobs/id/802
October 8, 2025 at 1:18 PM
PhD position on Regulation and Evolution of Bacterial Multicellularity ( #Streptomyces ) within @spp2389.bsky.social supervised by Natalia Tschowri (Hannover 🇩🇪) and Danny Rozen (Leiden 🇳🇱) with research at both locations
deadline: October 31, 2025
www.uni-hannover.de/en/jobs/id/802
deadline: October 31, 2025
www.uni-hannover.de/en/jobs/id/802
Reposted by Habeeb
New ERC funded computational postdoc position in my lab! We are looking for someone who will study the genomics of bacterial evolution using samples from experimental evolution and clinical trials. Lots of opportunities for interesting and fun collaboration!
my.corehr.com/pls/uoxrecru...
my.corehr.com/pls/uoxrecru...
Job Details
my.corehr.com
September 25, 2025 at 2:31 PM
New ERC funded computational postdoc position in my lab! We are looking for someone who will study the genomics of bacterial evolution using samples from experimental evolution and clinical trials. Lots of opportunities for interesting and fun collaboration!
my.corehr.com/pls/uoxrecru...
my.corehr.com/pls/uoxrecru...
Reposted by Habeeb
🚨 Microbiologists! We are recruiting Assistant / Associate Professors in 3 collaborative areas of our U. Pittsburgh School of Medicine.
1) MMG (my dept): fundamental research in med micro
2) Peds ID / I4Kids institute
3) Center for Vaccine Research
🔗 to all 3 w/info: www.linkedin.com/posts/vaughn...
1) MMG (my dept): fundamental research in med micro
2) Peds ID / I4Kids institute
3) Center for Vaccine Research
🔗 to all 3 w/info: www.linkedin.com/posts/vaughn...
Faculty Professor Associate - Full-Time | Vaughn Cooper
We are recruiting Faculty microbiologists in three (3) different, complementary, and collaborative areas at the University of Pittsburgh associated with the School of Medicine.
1) Fundamental researc...
www.linkedin.com
September 23, 2025 at 10:31 PM
🚨 Microbiologists! We are recruiting Assistant / Associate Professors in 3 collaborative areas of our U. Pittsburgh School of Medicine.
1) MMG (my dept): fundamental research in med micro
2) Peds ID / I4Kids institute
3) Center for Vaccine Research
🔗 to all 3 w/info: www.linkedin.com/posts/vaughn...
1) MMG (my dept): fundamental research in med micro
2) Peds ID / I4Kids institute
3) Center for Vaccine Research
🔗 to all 3 w/info: www.linkedin.com/posts/vaughn...
Reposted by Habeeb
Rifampicin is more effective against biofilm infections because it targets biofilm-forming mutants that are highly resistant to other antibiotics @niaidnews.bsky.social
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
September 17, 2025 at 10:28 PM
Rifampicin is more effective against biofilm infections because it targets biofilm-forming mutants that are highly resistant to other antibiotics @niaidnews.bsky.social
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Habeeb
Genome evolution of Acinetobacter baylyi ADP1 during laboratory domestication: acquired mutations impact competence and metabolism
#ApplEnvironMicrobiol from Jeff Barrick
journals.asm.org/doi/10.1128/...
#ApplEnvironMicrobiol from Jeff Barrick
journals.asm.org/doi/10.1128/...
Genome evolution of Acinetobacter baylyi ADP1 during laboratory domestication: acquired mutations impact competence and metabolism | Applied and Environmental Microbiology
Acinetobacter baylyi ADP1 is a bacterial chassis of interest to microbiologists in academia and industry
due to its extreme natural competence and wide metabolic range. Its ability to take
up DNA from...
journals.asm.org
September 18, 2025 at 11:14 AM
Genome evolution of Acinetobacter baylyi ADP1 during laboratory domestication: acquired mutations impact competence and metabolism
#ApplEnvironMicrobiol from Jeff Barrick
journals.asm.org/doi/10.1128/...
#ApplEnvironMicrobiol from Jeff Barrick
journals.asm.org/doi/10.1128/...
Reposted by Habeeb
We are looking for a 3-year postdoc to work with Daniel Probst, Justin van der Hooft and myself on an exciting project involving federated learning and integrative omics for discovery of new antibiotics from natural products.
Apply here: www.wur.nl/en/vacancy/p...
Please share!
Apply here: www.wur.nl/en/vacancy/p...
Please share!
www.wur.nl
September 8, 2025 at 9:07 AM
We are looking for a 3-year postdoc to work with Daniel Probst, Justin van der Hooft and myself on an exciting project involving federated learning and integrative omics for discovery of new antibiotics from natural products.
Apply here: www.wur.nl/en/vacancy/p...
Please share!
Apply here: www.wur.nl/en/vacancy/p...
Please share!
Reposted by Habeeb
Dissecting microbial communities with single-cell transcriptome analysis www.science.org/doi/abs/10.1... #jcampubs
Dissecting microbial communities with single-cell transcriptome analysis
Revealing insights into the function of microbial communities requires moving beyond measuring bulk taxonomic composition to detecting interactions between subpopulations. Following the transformative...
www.science.org
September 8, 2025 at 4:03 PM
Dissecting microbial communities with single-cell transcriptome analysis www.science.org/doi/abs/10.1... #jcampubs
Reposted by Habeeb
Dr. Michael Manhart at Rutgers is recruiting a Ph.D. student in microbial ecology, evolution, and systems biology for Fall 2026. Please share!
#microsky
#microsky
September 2, 2025 at 6:31 PM
Dr. Michael Manhart at Rutgers is recruiting a Ph.D. student in microbial ecology, evolution, and systems biology for Fall 2026. Please share!
#microsky
#microsky
Reposted by Habeeb
Three postdoc positions are now open for applications! Live and work on Kaurna land (Adelaide) in sunny South Australia. We have beach views, wineries, kangaroos, and koalas.
Develop new synthetic biology to engineer and understand #phage, and computational tools for #phage and #microbiome analysis
Develop new synthetic biology to engineer and understand #phage, and computational tools for #phage and #microbiome analysis
August 29, 2025 at 9:41 AM
Three postdoc positions are now open for applications! Live and work on Kaurna land (Adelaide) in sunny South Australia. We have beach views, wineries, kangaroos, and koalas.
Develop new synthetic biology to engineer and understand #phage, and computational tools for #phage and #microbiome analysis
Develop new synthetic biology to engineer and understand #phage, and computational tools for #phage and #microbiome analysis
Reposted by Habeeb
Yes reach out to Yasin for this project. It will allow a worldwide picture of the environmental metabolome. This can be already published or not yet published data but will need world coordinates.
Interested in a co-authorship?
We’re building a tool for repository-scale untargeted #metabolomics and #exposomics of #environmental data. To make it the best it can be, we’re looking for people willing to share high-resolution LC-MS/MS (DDA) data from #water, #soil, #sediment, and related samples.
We’re building a tool for repository-scale untargeted #metabolomics and #exposomics of #environmental data. To make it the best it can be, we’re looking for people willing to share high-resolution LC-MS/MS (DDA) data from #water, #soil, #sediment, and related samples.
August 26, 2025 at 9:46 PM
Yes reach out to Yasin for this project. It will allow a worldwide picture of the environmental metabolome. This can be already published or not yet published data but will need world coordinates.
Reposted by Habeeb
Another PDRA position! Join our team exploring how the mammalian immune system shapes microbiome ecology & evolution, and vice versa. In collaboration with @hepworth-lab.bsky.social funded by the @wellcometrust.bsky.social
www.jobs.manchester.ac.uk/Job/JobDetai...
www.jobs.manchester.ac.uk/Job/JobDetai...
Research Associate in Microbial Ecology:Oxford Road
www.jobs.manchester.ac.uk
August 27, 2025 at 8:52 AM
Another PDRA position! Join our team exploring how the mammalian immune system shapes microbiome ecology & evolution, and vice versa. In collaboration with @hepworth-lab.bsky.social funded by the @wellcometrust.bsky.social
www.jobs.manchester.ac.uk/Job/JobDetai...
www.jobs.manchester.ac.uk/Job/JobDetai...
Reposted by Habeeb
The Weisberg Lab at Oregon State University is recruiting a postdoctoral scholar in molecular microbiology to study mobile genetic element host range and transmission in microbial communities. Please see the full job description here: files-dev.cqls.oregonstate.edu/Weisberg_Lab...
August 25, 2025 at 11:45 PM
The Weisberg Lab at Oregon State University is recruiting a postdoctoral scholar in molecular microbiology to study mobile genetic element host range and transmission in microbial communities. Please see the full job description here: files-dev.cqls.oregonstate.edu/Weisberg_Lab...
Reposted by Habeeb
I cannot fully put into words what publishing this Review has meant to me, so I leave you with how we closed the paper.
"The humble bacterium is still a relevant tool for the study of the underlying mechanisms that are conserved throughout life."
🧪🧫🧬📚
doi.org/10.1093/gene...
"The humble bacterium is still a relevant tool for the study of the underlying mechanisms that are conserved throughout life."
🧪🧫🧬📚
doi.org/10.1093/gene...
The nature of mutation: a legacy of bacterial genetics
Abstract. A central question in the fields of genetics and evolution was the nature and origin of spontaneous mutation. Bacterial genetic experiments throu
doi.org
August 25, 2025 at 4:48 PM
I cannot fully put into words what publishing this Review has meant to me, so I leave you with how we closed the paper.
"The humble bacterium is still a relevant tool for the study of the underlying mechanisms that are conserved throughout life."
🧪🧫🧬📚
doi.org/10.1093/gene...
"The humble bacterium is still a relevant tool for the study of the underlying mechanisms that are conserved throughout life."
🧪🧫🧬📚
doi.org/10.1093/gene...
Reposted by Habeeb
🚨 Job alert 🚨
I’m recruiting two postdoctoral research associates to join my lab at KCL to study how #Klebsiella pneumoniae regulates virulence factor expression during infection! #klebclub
Mol Micro: tinyurl.com/mtrwtx5e
Infection: tinyurl.com/2s3u8ca2
Deadline: 21st September.
I’m recruiting two postdoctoral research associates to join my lab at KCL to study how #Klebsiella pneumoniae regulates virulence factor expression during infection! #klebclub
Mol Micro: tinyurl.com/mtrwtx5e
Infection: tinyurl.com/2s3u8ca2
Deadline: 21st September.
Postdoctoral Research Associate in Molecular Microbiology
www.kcl.ac.uk
August 26, 2025 at 2:40 PM
🚨 Job alert 🚨
I’m recruiting two postdoctoral research associates to join my lab at KCL to study how #Klebsiella pneumoniae regulates virulence factor expression during infection! #klebclub
Mol Micro: tinyurl.com/mtrwtx5e
Infection: tinyurl.com/2s3u8ca2
Deadline: 21st September.
I’m recruiting two postdoctoral research associates to join my lab at KCL to study how #Klebsiella pneumoniae regulates virulence factor expression during infection! #klebclub
Mol Micro: tinyurl.com/mtrwtx5e
Infection: tinyurl.com/2s3u8ca2
Deadline: 21st September.
Reposted by Habeeb
Excited to share the first results from my postdoc at @dmf-unil.bsky.social with @saramitri.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Microbes release lower-value metabolites at higher rates
Microbes release a wide range of metabolites into their environment, yet the reasons for this release and the factors that influence release rates are not well understood. Here, using a combination of...
www.biorxiv.org
August 20, 2025 at 8:31 AM
Excited to share the first results from my postdoc at @dmf-unil.bsky.social with @saramitri.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Habeeb
Biofilm-associated molecular patterns: BAMPs
in Infect Immune by Peter Østrup Jensen, Morten Rybtke, and Tim Tolker-Nielsen
journals.asm.org/doi/10.1128/...
in Infect Immune by Peter Østrup Jensen, Morten Rybtke, and Tim Tolker-Nielsen
journals.asm.org/doi/10.1128/...
Biofilm-associated molecular patterns: BAMPs | Infection and Immunity
Biofilms are implicated in a wide range of infections, posing a major challenge to
both healthcare and patient outcomes. These structured microbial communities are involved
in a variety of infections,...
journals.asm.org
August 22, 2025 at 10:47 AM
Biofilm-associated molecular patterns: BAMPs
in Infect Immune by Peter Østrup Jensen, Morten Rybtke, and Tim Tolker-Nielsen
journals.asm.org/doi/10.1128/...
in Infect Immune by Peter Østrup Jensen, Morten Rybtke, and Tim Tolker-Nielsen
journals.asm.org/doi/10.1128/...
Reposted by Habeeb
Check out our latest preprint where we show synergistic interactions between bacteria for the degradation of complex polysaccharides 🌊🦠🔺
@envsysmicro.at @akshitg.bsky.social
#MicroSky
www.biorxiv.org/content/10.1...
@envsysmicro.at @akshitg.bsky.social
#MicroSky
www.biorxiv.org/content/10.1...
A division of labor controls the degradation of fucoidans in the ocean
Fucoidans, complex polysaccharides produced by brown algae and diatoms, contribute to long-term carbon sequestration due to their resistance to microbial degradation1,2. While individual microbes can ...
www.biorxiv.org
August 14, 2025 at 11:32 AM
Check out our latest preprint where we show synergistic interactions between bacteria for the degradation of complex polysaccharides 🌊🦠🔺
@envsysmicro.at @akshitg.bsky.social
#MicroSky
www.biorxiv.org/content/10.1...
@envsysmicro.at @akshitg.bsky.social
#MicroSky
www.biorxiv.org/content/10.1...
Reposted by Habeeb
#microsky
We challenge the long-standing view that peptidoglycan alone protects cells from bursting.
Our study shows that the periplasm — enclosed by OM–PG connections — acts as a pressure buffer essential for osmoprotection in Gram-negative bacteria.
📄 www.nature.com/articles/s41...
We challenge the long-standing view that peptidoglycan alone protects cells from bursting.
Our study shows that the periplasm — enclosed by OM–PG connections — acts as a pressure buffer essential for osmoprotection in Gram-negative bacteria.
📄 www.nature.com/articles/s41...
Peptidoglycan–outer membrane attachment generates periplasmic pressure to prevent lysis in Gram-negative bacteria - Nature Microbiology
Outer membrane attachment to peptidoglycan enables periplasmic pressure to build up and counter cytoplasmic turgor pressure, preventing lysis during osmotic challenges in Escherichia coli.
www.nature.com
July 29, 2025 at 1:23 PM
#microsky
We challenge the long-standing view that peptidoglycan alone protects cells from bursting.
Our study shows that the periplasm — enclosed by OM–PG connections — acts as a pressure buffer essential for osmoprotection in Gram-negative bacteria.
📄 www.nature.com/articles/s41...
We challenge the long-standing view that peptidoglycan alone protects cells from bursting.
Our study shows that the periplasm — enclosed by OM–PG connections — acts as a pressure buffer essential for osmoprotection in Gram-negative bacteria.
📄 www.nature.com/articles/s41...
Reposted by Habeeb
Ever wondered why some antibiotics are made by Streptomyces on agar plates but not in liquid cultures? Read this work on redox control of antibiotic biosynthesis. Led by katienoble241.bsky.social and Rebecca Devine, and in collaboration with @barriewilks.bsky.social
journals.asm.org/doi/10.1128/...
journals.asm.org/doi/10.1128/...
journals.asm.org
August 7, 2025 at 4:30 PM
Ever wondered why some antibiotics are made by Streptomyces on agar plates but not in liquid cultures? Read this work on redox control of antibiotic biosynthesis. Led by katienoble241.bsky.social and Rebecca Devine, and in collaboration with @barriewilks.bsky.social
journals.asm.org/doi/10.1128/...
journals.asm.org/doi/10.1128/...
Reposted by Habeeb
Feels surreal to say but: I'm hiring! If you are or know anyone interested in looking at the evolution of phage resistance using A. baumannii and natural transformation, then this might be for you
www.jobbnorge.no/en/available...
www.jobbnorge.no/en/available...
Research position in Microbial Pharmacology and Population Biology (282139) | UiT The Arctic University of Norway
Job title: Research position in Microbial Pharmacology and Population Biology (282139), Employer: UiT The Arctic University of Norway, Deadline: Wednesday, August 27, 2025
www.jobbnorge.no
August 8, 2025 at 7:52 AM
Feels surreal to say but: I'm hiring! If you are or know anyone interested in looking at the evolution of phage resistance using A. baumannii and natural transformation, then this might be for you
www.jobbnorge.no/en/available...
www.jobbnorge.no/en/available...
Reposted by Habeeb
We are also hiring a 4-year postdoc to study the dynamics and evolution of mobile genetic elements in the C-fixing Icelandic host-spring microbiomes
Join our exciting multidisciplinary team funded by @ukri.org BBSRC sLoLa
www.jobs.manchester.ac.uk/Job/JobDetai...
Join our exciting multidisciplinary team funded by @ukri.org BBSRC sLoLa
www.jobs.manchester.ac.uk/Job/JobDetai...
August 13, 2025 at 10:41 AM
We are also hiring a 4-year postdoc to study the dynamics and evolution of mobile genetic elements in the C-fixing Icelandic host-spring microbiomes
Join our exciting multidisciplinary team funded by @ukri.org BBSRC sLoLa
www.jobs.manchester.ac.uk/Job/JobDetai...
Join our exciting multidisciplinary team funded by @ukri.org BBSRC sLoLa
www.jobs.manchester.ac.uk/Job/JobDetai...
Reposted by Habeeb
🚨 Highly recommended position open as Scientific Officer at the NCCR AntiResist consortium - a unique opportunity to play a central role in this fantastic research setup! 🦠🧬💊
📢 🚀 We are hiring! 🔎 🙏
Scientific Officer (80-100%)
👉A rare opportunity to play a central part in coordinating the research activities of NCCR AntiResist.
Come and join us! 👉 www.nccr-antiresist.ch/join-us/
#TransformingAntimicrobialResearch
#hiring #job #science #research
Scientific Officer (80-100%)
👉A rare opportunity to play a central part in coordinating the research activities of NCCR AntiResist.
Come and join us! 👉 www.nccr-antiresist.ch/join-us/
#TransformingAntimicrobialResearch
#hiring #job #science #research
August 11, 2025 at 8:46 AM
🚨 Highly recommended position open as Scientific Officer at the NCCR AntiResist consortium - a unique opportunity to play a central role in this fantastic research setup! 🦠🧬💊