Gavin Wilson
@gww.bsky.social
Assistant Scientist at the University Health Network and Assistant Professor at the University of Toronto.
Esophageal Adenocarcinoma and Lung Transplant Bioinformatics/Genomics
Esophageal Adenocarcinoma and Lung Transplant Bioinformatics/Genomics
Reposted by Gavin Wilson
⚠️New study: we mapped DNA-binding of topoisomerase TOP2B in cancer, uncovering surprising hotspots of DNA damage. TOP2B, normally essential for DNA stress relief, can act as a double-edged sword. co-led by @LiisUuskula @ChristianLee, out now @natcomms.nature.com www.nature.com/articles/s41... [1/7]
Topoisomerase IIb binding delineates localized mutational processes and driver mutations in cancer genomes - Nature Communications
Topoisomerases resolve topological DNA stress via double-strand breaks and are established targets of cancer chemotherapies. Here, the authors link genomic binding of TOP2B with localized mutational p...
www.nature.com
November 30, 2025 at 9:31 PM
⚠️New study: we mapped DNA-binding of topoisomerase TOP2B in cancer, uncovering surprising hotspots of DNA damage. TOP2B, normally essential for DNA stress relief, can act as a double-edged sword. co-led by @LiisUuskula @ChristianLee, out now @natcomms.nature.com www.nature.com/articles/s41... [1/7]
Reposted by Gavin Wilson
Repost the work-week crowd ;)
Sassy is out now!
Ever need to search for approximate matches of short DNA strings?
Sassy is the tool to use!
Available now wherever you get your code
With @rickbitloo.bsky.social
curiouscoding.nl/papers/sassy...
github.com/ragnarGrootK...
Ever need to search for approximate matches of short DNA strings?
Sassy is the tool to use!
Available now wherever you get your code
With @rickbitloo.bsky.social
curiouscoding.nl/papers/sassy...
github.com/ragnarGrootK...
July 21, 2025 at 10:30 AM
Repost the work-week crowd ;)
Reposted by Gavin Wilson
minimap2 adds support for short read spliced RNA-seq alignment! lh3.github.io/2025/04/18/s...
Short RNA-seq read alignment with minimap2
lh3.github.io
April 18, 2025 at 9:58 PM
minimap2 adds support for short read spliced RNA-seq alignment! lh3.github.io/2025/04/18/s...
Reposted by Gavin Wilson
UHN's newest documentary—The Future of Transplant—shines a light on the historic accomplishments of @transplant-uhn.bsky.social, setting the stage for innovative breakthroughs transforming #transplant today! ✨🫁
Learn more about the legacy and people behind the discoveries ⬇️
Learn more about the legacy and people behind the discoveries ⬇️
WATCH The Future of Transplant, a new documentary from UHN 📺🫁
Discover the history of lung transplant, from the world's first successful transplant in 1983 to a routine surgery performed 200x each year at UHN's Ajmera Transplant Centre.
Watch the full doc on YouTube:
youtu.be/3-84OghL8vU?...
Discover the history of lung transplant, from the world's first successful transplant in 1983 to a routine surgery performed 200x each year at UHN's Ajmera Transplant Centre.
Watch the full doc on YouTube:
youtu.be/3-84OghL8vU?...
March 20, 2025 at 7:09 PM
UHN's newest documentary—The Future of Transplant—shines a light on the historic accomplishments of @transplant-uhn.bsky.social, setting the stage for innovative breakthroughs transforming #transplant today! ✨🫁
Learn more about the legacy and people behind the discoveries ⬇️
Learn more about the legacy and people behind the discoveries ⬇️
Reposted by Gavin Wilson
Reposted by Gavin Wilson
I made a starter pack for algorithmic genomics. It's certainly incomplete, but already has a ton of awesome peeps. Let me know if you know people I should add (with a focus on algorithms and data structures in genomics)
go.bsky.app/TRWCnZs
go.bsky.app/TRWCnZs
November 12, 2024 at 2:03 PM
I made a starter pack for algorithmic genomics. It's certainly incomplete, but already has a ton of awesome peeps. Let me know if you know people I should add (with a focus on algorithms and data structures in genomics)
go.bsky.app/TRWCnZs
go.bsky.app/TRWCnZs