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Research at UHN
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Research news from Canada's largest research hospital.
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Driving Discovery. Delivering Impact.🎯

A story of science that’s bold, transformative, and collaborative.

This #WorldScienceDay, explore our annual research report and discover how @uhn.ca is building #AHealthierWorld.

➡️: www.uhnresearch.ca/Research-Rep...

#RR25 #DiscoveryToImpact
As 2025 comes to a close, we look forward to a new year full of opportunities to continue creating #AHealthierWorld.

Happy holidays from @uhnresearch.ca!
December 22, 2025 at 4:41 PM
A @uhn.ca study reveals gaps in #HepatitisC care for pregnant people.

Fewer than 10% of patients began treatment within 5 years of diagnosis, and many had multiple pregnancies before treatment. This highlights the need for stronger linkage-to-care.

🔗 Read more: doi.org/10.1093/cid/...
December 18, 2025 at 8:02 PM
New publication alert!

@uhn.ca's Dr. Viswanathan leads international experts on #MesenchymalStromalCells mechanism of action. Identifying research gaps and future directions will help boost the safety and efficacy of MSCs for conditions like #Arthritis.

🔗: www.isct-cytotherapy.org/article/S146...
Fate and Function of Exogenously Administered MSCs: Current Insights and Future Directions
The in vivo fate of mesenchymal stromal cells (MSCs), including their clearance, interaction with host tissues, and persistence, remains incompletely understood following systemic or local clinical ad...
www.isct-cytotherapy.org
December 18, 2025 at 4:18 PM
🎉 Congratulations to @uhn.ca’s Dr. Sonya MacParland on receiving funding through ERDERA’s Joint Transnational Call 2025!

This patient-partnered project advances research in primary sclerosing cholangitis (PSC)—a rare liver disease with no approved treatments.

Learn more ⬇️
ERDERA's Joint Transnational Call 2025 results are out 🎉 18 projects have been selected representing ~€29 million in funding for preclinical research on rare disease therapies🔬
👉 Discover the selected projects and how they adress the call's core aims: https://loom.ly/BAShwKw #ERDERA #RareDisease
ERDERA announces first Joint Transnational Call 2025 portfolio of preclinical therapy projects for rare diseases - ERDERA
Eighteen international pre clinical therapy projects selected under ERDERA’s first Joint Transnational Call will accelerate treatment options for people living with rare diseases across Europe and beyond
erdera.org
December 17, 2025 at 6:06 PM
Ice remains one of winter’s biggest hazards.❄️ A new study from @kiteuhn.bsky.social finds that even top-rated winter boots do not fully prevent slips, highlighting the need for additional safety measures.

🔗 Read more: www.uhnresearch.ca/news/ice-win...
December 17, 2025 at 4:16 PM
A @dkjei-uhn.bsky.social team is moving us closer to a future where blindness may not be inevitable in #RetinitisPigmentosa (RP). 👁️

In a new study, the team offer a new lab RP model and a first look at the disease’s development.

🔗 Read more: www.uhnresearch.ca/news/retinal...
December 15, 2025 at 5:19 PM
Innovation in neurovascular care!

Dr. Pascal Mosimann at @kbi-uhn.bsky.social has developed MagFlow, a microcatheter system that uses blood flow to navigate vessels 270% smaller than ever before.

This could transform treatment for #stroke, aneurysms & more.

🔗: www.uhnresearch.ca/news/microca...
December 12, 2025 at 4:51 PM
New research from @kiteuhn.bsky.social explores how adapting mindfulness practices can remove barriers for individuals with spinal cord injury, supporting psychological well-being and recovery.

🔗 Read more: www.uhnresearch.ca/news/mindful...

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@uhn.ca
December 11, 2025 at 4:07 PM
Researchers from @uhn.ca have built ECG-FM, an open-source #AI model that can deliver faster, more consistent heart screening and risk assessment by interpreting electrocardiogram data. 💓

🔗 Read more: www.uhnresearch.ca/news/harness...
December 10, 2025 at 4:16 PM
UHN is proud to be ranked #1 on the list of Canada’s Top 40 Research Hospitals from Research Infosource Inc. for the 15th year in a row!

Thanks to our incredible research community for their continued dedication to #HealthDiscovery, #care & #education!

🔗: www.uhnresearch.ca/news/uhn-can...
December 4, 2025 at 3:13 PM
Reposted by Research at UHN
A novel inhibitor, developed by Dr. Keith Stewart’s team at @uhn.ca's @pmresearch-uhn.bsky.social, successfully blocked cancer cell’s recycling system in multiple myeloma. It also shows promise for boosting anti-tumour immunity and for use in other blood malignancy.

doi.org/10.1182/bloo...
December 2, 2025 at 4:21 PM
Read about the latest findings from Canada’s largest #research hospital in @uhn.ca’s Research Spotlight newsletter:

▶️ Reducing heart risk in #kidney care
▶️ Hand rehabilitation with #AI
▶️ Preserving the blood-brain barrier after #stroke
+ More

🔗: www.uhnresearch.ca/news/researc...
November 28, 2025 at 2:37 PM
A new study from @pmresearch-uhn.bsky.social shows that combining two drugs (enasidenib with venetoclax) can help people with hard-to-treat #AcuteMyeloidLeukemia achieve remission.

This offers hope for longer remissions and easier outpatient care.

🔗 Read more: www.uhnresearch.ca/news/promisi...
November 27, 2025 at 3:58 PM
Reposted by Research at UHN
Today the Princess Margaret Cancer Foundation announced an unprecedented donation. The $50 million gift, donated by Peter Gilgan Foundation, will establish the Peter Gilgan Centre for Early Cancer Detection Research at UHN's Princess Margaret Cancer Centre.

Read more:
https://bit.ly/4rochiw
November 26, 2025 at 10:25 PM
From bold ideas to real-world solutions, research at UHN is ‘Driving Discovery. Delivering Impact’. 🎯

Thank you for collaborating with us as we build #AHealthierWorld for all.

➡️ Explore more in our Research Report: www.uhnresearch.ca/Research-Rep...

#RR25 #DiscoveryToImpact
November 26, 2025 at 4:34 PM
Celebrating our award-winning scientists whose discoveries are driving impact today and shaping the innovations of tomorrow.

➡️ Join us in honouring their remarkable achievements in health research: www.uhnresearch.ca/Research-Rep...

#RR25 #DiscoveryToImpact
November 24, 2025 at 4:02 PM
Could VR transform eye care? 👀 A review by Drs. Michael Reber & Lora Appel from @uhn.ca explores how immersive tech can improve accessibility and outcomes.

Learn more: doi.org/10.3390/tech...

#VisionCare #DigitalHealth
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@dkjei-uhn.bsky.social @kiteuhn.bsky.social
November 21, 2025 at 4:32 PM
@uhn.ca's Patient Engagement in Research (@piper-uhn.bsky.social) team recently hosted its 3rd annual Research Day. Over 200 attendees explored how partnering with people with lived experience (PLEX) makes research more relevant & impactful. Read more: www.uhnresearch.ca/news/piper-r...
November 20, 2025 at 7:07 PM
This year, thousands of supporters came together with the PMCF to raise funds for cancer research and care.

Together, we are lighting the way forward for cancer patients and their loved ones.

➡️ Learn how we ‘Carry The Fire’: www.uhnresearch.ca/Research-Rep...

#RR25 #DiscoveryToImpact
November 20, 2025 at 5:19 PM
New publication alert! 🚨 @uhn.ca trainee Anthaea-Grace and Senior Scientist Dr. Antonio Strafella, together with their team, used #MachineLearning to combine neuroimaging and biofluid data—improving #Parkinson's classification accuracy.

Read it in PLoS ONE ➡ journals.plos.org/plosone/arti...
Using machine learning for detection of Parkinson’s disease and mild cognitive impairment
Background Parkinson’s disease is a movement disorder featuring motor symptoms and cognitive decline, which can manifest as mild cognitive impairment. The incidence of mild cognitive impairment increa...
journals.plos.org
November 19, 2025 at 8:34 PM
Thirteen years ago, Shilpa received a double-lung transplant at @uhn.ca—made possible by an innovation funded entirely through philanthropy.

This year, UHN Foundation raised $221M to support life-saving work at UHN.

➡️ Read more: www.uhnresearch.ca/Research-Rep...

#RR25 #DiscoveryToImpact
November 19, 2025 at 5:52 PM
When science steps beyond silos, solutions reach the people who need them most.

This is the vision behind UHN’s Collaborative Centres.

➡️ Learn about these Centres and how we are ‘Collaborating for Impact’: www.uhnresearch.ca/Research-Rep...

#RR25 #DiscoveryToImpact
November 18, 2025 at 4:39 PM
Rebuilding human heart tissue. Harnessing #AI for precision care.

@uhn.ca researchers are ‘Pushing the Boundaries of Research’ and redefining what’s possible.

➡️ Discover the innovations shaping the future of health research: www.uhnresearch.ca/Research-Rep...

#RR25 #DiscoveryToImpact
November 17, 2025 at 4:19 PM
#ICYMI 🔬 A @uhn.ca @kbi-uhn.bsky.social research team uncovered how nervous system cells activate to repair #SpinalCordInjuries.

Targeting this process could lead to new treatments.

Read their recent publication in Nature Neurology here ➡️ www.nature.com/articles/s41...
November 14, 2025 at 8:39 PM
Advancing research with and for communities.

Equity should be built into every stage of care. @uhn.ca researchers are ‘Transforming the Landscape’ by reducing barriers and addressing cultural safety.

➡️ Learn more: www.uhnresearch.ca/Research-Rep...

#RR25 #DiscoveryToImpact
November 14, 2025 at 4:23 PM