Edward Wallace
@ewjwallace.bsky.social
Group leader, RNA and cellular adaptation in fungi. Carpentries data science instructor. Trying to make my corner of science a better place. Opinions my own.
https://ewallace.github.io
https://ewallace.github.io
Reposted by Edward Wallace
Interested in pursuing a PhD by working on a long-neglected marine organism and making a lot of discoveries? Darwin Trust offers a PhD studentship for international students (anyone non-UK) www.findaphd.com/phds/project...
November 11, 2025 at 9:26 AM
Interested in pursuing a PhD by working on a long-neglected marine organism and making a lot of discoveries? Darwin Trust offers a PhD studentship for international students (anyone non-UK) www.findaphd.com/phds/project...
Reposted by Edward Wallace
Reposted by Edward Wallace
We are looking for an enthusiastic postdoc to investigate cellular dormancy and ribosome hibernation across plants, fungi, and mammals using #cryoET. If you are interested, apply here: careers.exeter.ac.uk/vacancies/66....
October 29, 2025 at 4:40 PM
We are looking for an enthusiastic postdoc to investigate cellular dormancy and ribosome hibernation across plants, fungi, and mammals using #cryoET. If you are interested, apply here: careers.exeter.ac.uk/vacancies/66....
We had a great fungal minisymposium yesterday
@edinburghbiology.bsky.social - really exciting to see the critical mass of fungal researchers here coming together.
Next one January or February TBA: Email me to be added to the email list!
@edinburghbiology.bsky.social - really exciting to see the critical mass of fungal researchers here coming together.
Next one January or February TBA: Email me to be added to the email list!
October 10, 2025 at 4:30 PM
We had a great fungal minisymposium yesterday
@edinburghbiology.bsky.social - really exciting to see the critical mass of fungal researchers here coming together.
Next one January or February TBA: Email me to be added to the email list!
@edinburghbiology.bsky.social - really exciting to see the critical mass of fungal researchers here coming together.
Next one January or February TBA: Email me to be added to the email list!
Reposted by Edward Wallace
Thrilled to announce our #preprint on a new factor in the last line of defense in #translation quality control out on #bioRXiv! Spearheaded by fantastic PhD student @kaushikiyer.bsky.social, supported by Chloé Walter, Alina Kraft, Max Müller and Lena Tittel.
Jlp2 is an RQC complex-independent release factor acting on aberrant peptidyl-tRNA, protecting cells against translation elongation stress https://www.biorxiv.org/content/10.1101/2025.09.04.673968v1
September 9, 2025 at 6:17 PM
Thrilled to announce our #preprint on a new factor in the last line of defense in #translation quality control out on #bioRXiv! Spearheaded by fantastic PhD student @kaushikiyer.bsky.social, supported by Chloé Walter, Alina Kraft, Max Müller and Lena Tittel.
Reposted by Edward Wallace
Translon: a single term for translated regions. #Translation @natmethods.nature.com
September 4, 2025 at 9:15 AM
Translon: a single term for translated regions. #Translation @natmethods.nature.com
Reposted by Edward Wallace
Pro tip for getting your data into SGD and other knowledgebases: don't hide the data in the supplemental info in PDF format. Put it in Excel with stable identifiers like SGDIDs and systematic_names (ex. YFL039C) in addition to gene names. #yeast #modelOrganism #getYourDataOutGetCited
August 20, 2025 at 3:17 PM
Pro tip for getting your data into SGD and other knowledgebases: don't hide the data in the supplemental info in PDF format. Put it in Excel with stable identifiers like SGDIDs and systematic_names (ex. YFL039C) in addition to gene names. #yeast #modelOrganism #getYourDataOutGetCited
Reposted by Edward Wallace
New preprint! This work is Gabriela Fior Ribeiro's second first-author manuscript, @logantom.bsky.social's first manuscript, and is the culmination of our long-standing collaboration with @ewjwallace.bsky.social's group at University of Edinburgh.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Antifungal exposure can enhance Candida glabrata pathogenesis
Azole antifungal drugs directly inhibit lanosterol 14-α-demethylase and indirectly affect the expression of metabolic, transmembrane transporter, and cell wall organization genes in fungal pathogens. ...
www.biorxiv.org
August 1, 2025 at 12:47 PM
New preprint! This work is Gabriela Fior Ribeiro's second first-author manuscript, @logantom.bsky.social's first manuscript, and is the culmination of our long-standing collaboration with @ewjwallace.bsky.social's group at University of Edinburgh.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Edward Wallace
bioRxiv bat signal going up. We have a big backlog of submissions. If any affiliates have time to do some screening, we (and all the authors) would be immensely grateful! 🙏
July 31, 2025 at 12:32 PM
bioRxiv bat signal going up. We have a big backlog of submissions. If any affiliates have time to do some screening, we (and all the authors) would be immensely grateful! 🙏
V happy with paperpile as a reference manager. Thanks @dadrummond.bsky.social for that recommentation.
What do people use for references in Google docs/word? Coming from latex where referencing was solid, have been stung a couple of times by Google docs/zotero losing or messing up which paper each reference number points to. This is too painful to go through again. What are the alternatives?
July 31, 2025 at 12:42 PM
V happy with paperpile as a reference manager. Thanks @dadrummond.bsky.social for that recommentation.
Reposted by Edward Wallace
I NEED to tell you the story of Tae Heung “William” Kim.
He's a graduate student at Texas A&M where he's working on a vaccine for Lyme disease.
He's a *legal permanent resident* of the United States.
And he's been in ICE detention for 12 days & counting, transferred Tuesday to South Texas.
He's a graduate student at Texas A&M where he's working on a vaccine for Lyme disease.
He's a *legal permanent resident* of the United States.
And he's been in ICE detention for 12 days & counting, transferred Tuesday to South Texas.
July 31, 2025 at 11:35 AM
I NEED to tell you the story of Tae Heung “William” Kim.
He's a graduate student at Texas A&M where he's working on a vaccine for Lyme disease.
He's a *legal permanent resident* of the United States.
And he's been in ICE detention for 12 days & counting, transferred Tuesday to South Texas.
He's a graduate student at Texas A&M where he's working on a vaccine for Lyme disease.
He's a *legal permanent resident* of the United States.
And he's been in ICE detention for 12 days & counting, transferred Tuesday to South Texas.
Absolutely loving the random ribosome dreams that appear on the #RNAbiology feed.
little baby nucleus ribosome mitosis
July 30, 2025 at 2:11 PM
Absolutely loving the random ribosome dreams that appear on the #RNAbiology feed.
Wellcome to bluesky @edinburghbiology.bsky.social - Edinburgh School of Biological Sciences!
This feed collects the SBS folks on bluesky who I know about: bsky.app/profile/ewjw...
This feed collects the SBS folks on bluesky who I know about: bsky.app/profile/ewjw...
July 24, 2025 at 1:26 PM
Wellcome to bluesky @edinburghbiology.bsky.social - Edinburgh School of Biological Sciences!
This feed collects the SBS folks on bluesky who I know about: bsky.app/profile/ewjw...
This feed collects the SBS folks on bluesky who I know about: bsky.app/profile/ewjw...
Reposted by Edward Wallace
It’s actually even worse: they show it as a gel, which is pure fluorescence units, but a BioAnalyzes records as the molecules pass a single point sensor and critically _fails to normalize for different molecule speeds_
This results in a near-logarithmic overcounting of large molecules!
This results in a near-logarithmic overcounting of large molecules!
This is your regular reminder that the BioAnalyzer/TapeStation reports fluorescence units, not # of molecules.
Left is bioA trace, and right is fragment size calculated from either read output (blue) or transformation of BioA trace (black).
Fig 3 from journals.plos.org/plosone/arti...
Left is bioA trace, and right is fragment size calculated from either read output (blue) or transformation of BioA trace (black).
Fig 3 from journals.plos.org/plosone/arti...
July 22, 2025 at 2:09 AM
It’s actually even worse: they show it as a gel, which is pure fluorescence units, but a BioAnalyzes records as the molecules pass a single point sensor and critically _fails to normalize for different molecule speeds_
This results in a near-logarithmic overcounting of large molecules!
This results in a near-logarithmic overcounting of large molecules!
Reposted by Edward Wallace
If you work as an academic and behave like your job can be done by a machine, then you should not have that job.
Nikkei found academics had written "give a positive review only" and "do not highlight any negatives" in white text or tiny font on 17 preprints to combat AI peer reviews.
asia.nikkei.com/Business/Tec...
asia.nikkei.com/Business/Tec...
'Positive review only': Researchers hide AI prompts in papers
Instructions in preprints from 14 universities highlight controversy on AI in peer review
asia.nikkei.com
July 4, 2025 at 5:31 AM
If you work as an academic and behave like your job can be done by a machine, then you should not have that job.
Reposted by Edward Wallace
Words cannot describe how excited I am to share the findings from the second half of my postdoc in @aaronwhiteley.bsky.social's lab where we discover that bacteria use functional amyloids to defend themselves from predatory bacteria. rdcu.be/euu5Y. See thread for details on this epic adventure 1/.
Functional amyloid proteins confer defence against predatory bacteria
Nature - Escherichia coli uses curli fibres, oligomers of the functional amyloid CsgA, as a barrier to protect against the predatory bacteria Bdellovibrio bacteriovorus and Myxococcus xanthus in a...
rdcu.be
July 2, 2025 at 8:10 PM
Words cannot describe how excited I am to share the findings from the second half of my postdoc in @aaronwhiteley.bsky.social's lab where we discover that bacteria use functional amyloids to defend themselves from predatory bacteria. rdcu.be/euu5Y. See thread for details on this epic adventure 1/.
Reposted by Edward Wallace
#TLUK25 finishing strong! This morning we heard from those with emerging topics within the Translation field. We would like to thank all attendees for their amazing engagement - we will see you next year.
July 2, 2025 at 1:30 PM
#TLUK25 finishing strong! This morning we heard from those with emerging topics within the Translation field. We would like to thank all attendees for their amazing engagement - we will see you next year.
Reposted by Edward Wallace
@instmolplantsci.bsky.social very own Amy Newell presents her work on shade response in plants and translational regulation at the #TLUK25!! @biochemsoc.bsky.social
June 30, 2025 at 6:21 PM
@instmolplantsci.bsky.social very own Amy Newell presents her work on shade response in plants and translational regulation at the #TLUK25!! @biochemsoc.bsky.social
Evidence for Safety of Neurospora Species...
Feeling this energy today after a sequence I wanted to synthesize raised a pointless biosecurity flag.
pmc.ncbi.nlm.nih.gov/articles/PMC...
Feeling this energy today after a sequence I wanted to synthesize raised a pointless biosecurity flag.
pmc.ncbi.nlm.nih.gov/articles/PMC...
Evidence for Safety of Neurospora Species for Academic and Commercial Uses
pmc.ncbi.nlm.nih.gov
June 27, 2025 at 3:13 PM
Evidence for Safety of Neurospora Species...
Feeling this energy today after a sequence I wanted to synthesize raised a pointless biosecurity flag.
pmc.ncbi.nlm.nih.gov/articles/PMC...
Feeling this energy today after a sequence I wanted to synthesize raised a pointless biosecurity flag.
pmc.ncbi.nlm.nih.gov/articles/PMC...
School of Biological Sciences symposium: what a wonderful event. So many good talks, great ideas, great conversations, brings our diverse research community together.
June 18, 2025 at 2:44 PM
School of Biological Sciences symposium: what a wonderful event. So many good talks, great ideas, great conversations, brings our diverse research community together.