The treatment landscape for systemic lupus erythematosus (SLE) has shifted greatly in recent years, driven by the emergence of cell-based immunotherapies targeting pathogenic B-cell populations. Among...

People without university-educated parents are 36% likely to enrol in degree, compared with 59% of students whose parents are tertiary educated

The search to understand how the body keeps immunity in check

Claims of a link between paracetamol use in pregnancy and autism have been repeatedly disproven – despite what the US administration suggests I have treated more than 200,000 patients in almost 40 years of practising medicine. Autism is a complex disorder which can present in many different ways and in a spectrum of severity. Causation is a very important consideration and, as a paediatrician, I know that parents often ask why their child has autism. Particularly in the severe end of the autism spectrum, genetic disorders can present with autistic features; for example Angelman syndrome, Smith-Magenis syndrome, Williams syndrome and many others. However, for the majority of the children who are diagnosed with autism, no cause is found. We also know that the number of children diagnosed with autism in the developed world is increasing. There are many reasons for this, not least that we are better at diagnosing it. However, in my work I often heard the question “why is my child autistic?” Continue reading...

TGA confirms drug is safe for use in pregnancy as doctors worry about effect of White House misinformation

Sjögren’s disease (SjD) is a chronic systemic autoimmune disorder characterised by lymphocytic infiltration of the salivary and lacrimal glands, leadi…

Background Emerging therapies have the potential to be used in patients with severe refractory systemic lupus erythematosus (srSLE), but no agreed definition of srSLE exists. We evaluated a pilot srSL...

Hosted by Monash University's Faculty of Medicine, Nursing and Health Sciences, at the Monash University Prato Campus in Tuscany, the summit explored the theme “Enabling Technologies in Medicine”, off...

Systemic lupus erythematosus (SLE, lupus) remains an enigmatic diagnosis with a poor prognosis. SLE is characterised by complex biology and heterogene…

Lupus can be debilitating and sometimes deadly for the 3 million people who have it. A treatment called CAR T appears to stop it in its tracks.

In an Australian-first, Monash Health in collaboration with Monash University, has successfully treating a patient with the autoimmune condition lupus with CAR T-cell therapy. “It is absolutely a gam...

Obicetrapib is a highly selective cholesteryl ester transfer protein inhibitor that reduces low-density lipoprotein (LDL) cholesterol levels. The efficacy and safety of obicetrapib have not been fu...

Objectives To achieve consensus on domains of active disease for inclusion in a novel outcome measure for SLE randomised controlled trials (RCTs), the Treatment Response Measure for SLE (TRM-SLE).Meth...

In voting in Canada and Australia, right-wing parties that borrowed from the MAGA playbook were punished. Elsewhere, President Trump is having a more complex impact.