Emmanuelle Bignon
@emmabignon.bsky.social
Computational biochemistry, histone PTM, DNA damage, nucleosomes... fun stuff! | Young PI @ LPCT lab, Nancy, France | She/her
Reposted by Emmanuelle Bignon
Si vous avez des adolescentes qui s'intéressent à l'informatique, je signale qu'il reste des places pour les stages #GirlsCanCode en août et septembre.
C'est gratuit et vraiment top. Mes aînées les ont fait en 2018 et 2022, là je viens d'inscrire fille n°3 et elle est ravie.
girlscancode.fr
C'est gratuit et vraiment top. Mes aînées les ont fait en 2018 et 2022, là je viens d'inscrire fille n°3 et elle est ravie.
girlscancode.fr
Girls Can Code!
Stages d'initiation à la programmation Girls Can Code!
girlscancode.fr
July 22, 2025 at 2:00 PM
Si vous avez des adolescentes qui s'intéressent à l'informatique, je signale qu'il reste des places pour les stages #GirlsCanCode en août et septembre.
C'est gratuit et vraiment top. Mes aînées les ont fait en 2018 et 2022, là je viens d'inscrire fille n°3 et elle est ravie.
girlscancode.fr
C'est gratuit et vraiment top. Mes aînées les ont fait en 2018 et 2022, là je viens d'inscrire fille n°3 et elle est ravie.
girlscancode.fr
📣💻[JOB OFFER] I am looking for a postdoc with experience in QM/MM, MD and biosystems, and who would be motivated to study the formation mechanisms of oxydative histone modifications. Please share! #compchem #histones #PTM #redox #DNA
emploi.cnrs.fr/Offres/CDD/U...
emploi.cnrs.fr/Offres/CDD/U...
Portail Emploi CNRS - Offre d'emploi - Postdoc in computational biochemistry M/F
emploi.cnrs.fr
June 11, 2025 at 7:45 AM
Reposted by Emmanuelle Bignon
L'initiative européenne visant à interdire les thérapies de conversion dépasse les 500 000 signatures, avec une cadence de 120 par minute dans toute l'Europe !
On doit atteindre 1 million avant la fin de la journée de samedi ! On lâche rien !
eci.ec.europa.eu/043/public/#...
On doit atteindre 1 million avant la fin de la journée de samedi ! On lâche rien !
eci.ec.europa.eu/043/public/#...
European Citizens' Initiative
Give your support !
eci.ec.europa.eu
May 14, 2025 at 11:10 AM
L'initiative européenne visant à interdire les thérapies de conversion dépasse les 500 000 signatures, avec une cadence de 120 par minute dans toute l'Europe !
On doit atteindre 1 million avant la fin de la journée de samedi ! On lâche rien !
eci.ec.europa.eu/043/public/#...
On doit atteindre 1 million avant la fin de la journée de samedi ! On lâche rien !
eci.ec.europa.eu/043/public/#...
Reposted by Emmanuelle Bignon
Join us for the next #MDDBwebinar: DynaRepo and beyond, exploring macromolecular dynamics, allosteric signaling & binding site predictions - presented by researchers from Inria and LPCT, Université de Lorraine, France.
🗓️ May 27, 13:00 CEST
More info 🔗 bit.ly/43rQKeT
#MDDB #OpenScience #FAIRdata
🗓️ May 27, 13:00 CEST
More info 🔗 bit.ly/43rQKeT
#MDDB #OpenScience #FAIRdata
May 13, 2025 at 11:08 AM
Join us for the next #MDDBwebinar: DynaRepo and beyond, exploring macromolecular dynamics, allosteric signaling & binding site predictions - presented by researchers from Inria and LPCT, Université de Lorraine, France.
🗓️ May 27, 13:00 CEST
More info 🔗 bit.ly/43rQKeT
#MDDB #OpenScience #FAIRdata
🗓️ May 27, 13:00 CEST
More info 🔗 bit.ly/43rQKeT
#MDDB #OpenScience #FAIRdata
Reposted by Emmanuelle Bignon
Ever wondered what the lonely histone H3C110 does? We found that it’s lost in many fungi. Adding it back boosts histone H3 copper reductase activity, rescues iron defects and modulates lifespan, suggesting an evolutionary tradeoff between these effects.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Histone H3 cysteine 110 enhances iron metabolism and modulates replicative life span in Saccharomyces cerevisiae
Histone H3 cysteine 110 enhances iron metabolism and modulates replicative life span in yeast.
www.science.org
April 11, 2025 at 9:43 PM
Ever wondered what the lonely histone H3C110 does? We found that it’s lost in many fungi. Adding it back boosts histone H3 copper reductase activity, rescues iron defects and modulates lifespan, suggesting an evolutionary tradeoff between these effects.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Emmanuelle Bignon
Take a look at our new collaboration project with the Phil Cole lab, we demonstrate how SIRT6 can recognize and remove a variety of different Histone acylations!
🚨New paper🚨Our new study with the lab of Phil Cole uncovers how SIRT6 dynamically adapts structurally and enzymatically to target diverse histone acylations (e.g., H3K27ac) within nucleosomes. @jonmarkert.bsky.social
doi.org/10.1016/j.jb... #Chromatin #SIRT6 #CryoEM
doi.org/10.1016/j.jb... #Chromatin #SIRT6 #CryoEM
March 28, 2025 at 4:16 PM
Take a look at our new collaboration project with the Phil Cole lab, we demonstrate how SIRT6 can recognize and remove a variety of different Histone acylations!
Reposted by Emmanuelle Bignon
#Agenda Les 27 février, 3 mars et 4 mars 2025, l’association Femmes & Sciences organise des journées pour les lycéennes du Grand Est. Rencontres avec des femmes scientifiques et visites de labos pour déconstruire les stéréotypes et inspirer
➕ d'infos 👉 https://www.sharee.me/t/jkLw!
➕ d'infos 👉 https://www.sharee.me/t/jkLw!
February 14, 2025 at 7:55 AM
#Agenda Les 27 février, 3 mars et 4 mars 2025, l’association Femmes & Sciences organise des journées pour les lycéennes du Grand Est. Rencontres avec des femmes scientifiques et visites de labos pour déconstruire les stéréotypes et inspirer
➕ d'infos 👉 https://www.sharee.me/t/jkLw!
➕ d'infos 👉 https://www.sharee.me/t/jkLw!
I was a real pleasure to discuss about #stereotypes and #gender #bias for this international day of #women and #girls in #science! Thank you for the invitation! 😀 #GWB2025
Today we are happy to welcome @emmabignon.bsky.social for the #GWB2025 at @itodys.bsky.social @upcite.bsky.social @ctm-itodys.bsky.social
Very interesting meeting
Very interesting meeting
February 11, 2025 at 3:11 PM
Reposted by Emmanuelle Bignon
Today we are happy to welcome @emmabignon.bsky.social for the #GWB2025 at @itodys.bsky.social @upcite.bsky.social @ctm-itodys.bsky.social
Very interesting meeting
Very interesting meeting
February 11, 2025 at 10:43 AM
Today we are happy to welcome @emmabignon.bsky.social for the #GWB2025 at @itodys.bsky.social @upcite.bsky.social @ctm-itodys.bsky.social
Very interesting meeting
Very interesting meeting
Reposted by Emmanuelle Bignon
We have a new #tutorial posted online, this time for Gaussian-accelerated MD as implemented in NAMD. Article has been submitted to LiveCoMS, a great venue for such efforts. We welcome feedback! Yes, it's alanine dipeptide, but you have to start somewhere :) #compchem
github.com/Lemkul-Lab/g...
github.com/Lemkul-Lab/g...
GitHub - Lemkul-Lab/gamd_livecoms_tutorial
Contribute to Lemkul-Lab/gamd_livecoms_tutorial development by creating an account on GitHub.
github.com
January 21, 2025 at 7:21 PM
We have a new #tutorial posted online, this time for Gaussian-accelerated MD as implemented in NAMD. Article has been submitted to LiveCoMS, a great venue for such efforts. We welcome feedback! Yes, it's alanine dipeptide, but you have to start somewhere :) #compchem
github.com/Lemkul-Lab/g...
github.com/Lemkul-Lab/g...
It is still possible to apply to this postdoc position in my group if you are motivated by using your QM/MM and MD skills to study the fascinating histone post-translational modifications! 🥳
Deadline is the 1st of March #job #compchem #histones #DNA
Apply on the CNRS website : lnkd.in/eNxR-TPH
Deadline is the 1st of March #job #compchem #histones #DNA
Apply on the CNRS website : lnkd.in/eNxR-TPH
First post here, how exciting!! 🥳
📣💻[JOB OFFER] I am looking for a postdoc with experience in QM/MM, MD and biosystems, and who would be motivated to study the formation mechanisms of oxydative histone modifications. Please share! #compchem #histones #PTM #redox
www.linkedin.com/posts/activi...
📣💻[JOB OFFER] I am looking for a postdoc with experience in QM/MM, MD and biosystems, and who would be motivated to study the formation mechanisms of oxydative histone modifications. Please share! #compchem #histones #PTM #redox
www.linkedin.com/posts/activi...
Emmanuelle Bignon on LinkedIn: Job offer - pdoc CHROM
📢🧬I have a postdoc position open for people with experience using QM/MM on biosystems! Do not hesitate to apply if you're interested in investigating the…
www.linkedin.com
January 21, 2025 at 11:07 AM
It is still possible to apply to this postdoc position in my group if you are motivated by using your QM/MM and MD skills to study the fascinating histone post-translational modifications! 🥳
Deadline is the 1st of March #job #compchem #histones #DNA
Apply on the CNRS website : lnkd.in/eNxR-TPH
Deadline is the 1st of March #job #compchem #histones #DNA
Apply on the CNRS website : lnkd.in/eNxR-TPH
Reposted by Emmanuelle Bignon
My lab is looking to hire a Postdoc to study mechanisms of DNA repair in chromatin using biochemical, biophysical, and structural biology approaches! Feel free to share with anyone you think may be interested.
jobs.virginia.edu/us/en/job/R0...
jobs.virginia.edu/us/en/job/R0...
Postdoctoral Research Associate in Biochemistry and Molecular Genetics – Weaver Lab in Charlottesville, Virginia, United States of America | Research at University of Virginia
Apply for Postdoctoral Research Associate in Biochemistry and Molecular Genetics – Weaver Lab job with University of Virginia in Charlottesville, Virginia, United States of America. Research at Univer...
jobs.virginia.edu
January 16, 2025 at 8:35 PM
My lab is looking to hire a Postdoc to study mechanisms of DNA repair in chromatin using biochemical, biophysical, and structural biology approaches! Feel free to share with anyone you think may be interested.
jobs.virginia.edu/us/en/job/R0...
jobs.virginia.edu/us/en/job/R0...
Reposted by Emmanuelle Bignon
Work led by graduate student @trinitycookis.bsky.social and coauthors Alexandria Lydecker, @paulsauer.bsky.social, and @kasinath-lab.bsky.social is out today where we looked at the inhibition of PRC2 by histone PTMs associated with regions of active transcription.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Structural basis for the inhibition of PRC2 by active transcription histone posttranslational modifications - Nature Structural & Molecular Biology
Structures reveal that histone H3K36me3 and H3K4me3 modifications reduce Polycomb repressive complex 2 (PRC2) function through the inhibition of histone tail engagement and antagonistic binding to the...
www.nature.com
January 8, 2025 at 1:36 AM
Work led by graduate student @trinitycookis.bsky.social and coauthors Alexandria Lydecker, @paulsauer.bsky.social, and @kasinath-lab.bsky.social is out today where we looked at the inhibition of PRC2 by histone PTMs associated with regions of active transcription.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Emmanuelle Bignon
2024 - the year when we showed that chromatin structure is responsive to ROS regulation because of redox sensitive histone variants - more #redoxepigenetics in 2025 folks - thanks 2024 looking forward to an awesome 2025 www.cell.com/cell-reports...
Histone H3.1 is a chromatin-embedded redox sensor triggered by tumor cells developing adaptive phenotypic plasticity and multidrug resistance
Palma et al. report that H3.1Cys96 oxidation is a functional posttranslational modification involved in the regulation of gene expression. In breast cancer, H3.1Cys96 oxidation promotes resistance to first-line chemotherapeutic drugs and stimulates metastasis. They also show that suppressing H3.1Cys96 oxidation inhibits metastasis while resensitizing cancer cells to chemotherapy.
www.cell.com
December 31, 2024 at 6:08 PM
2024 - the year when we showed that chromatin structure is responsive to ROS regulation because of redox sensitive histone variants - more #redoxepigenetics in 2025 folks - thanks 2024 looking forward to an awesome 2025 www.cell.com/cell-reports...
Reposted by Emmanuelle Bignon
Scientists have long known that histones spool DNA and help regulate genes. They may be doing a lot more.
www.asbmb.org/asbmb-...
www.asbmb.org/asbmb-...
These proteins have been secretly managing your cells
Scientists have long known that histones spool DNA and help regulate genes. They may be doing a lot more.
www.asbmb.org
December 28, 2024 at 6:23 PM
Scientists have long known that histones spool DNA and help regulate genes. They may be doing a lot more.
www.asbmb.org/asbmb-...
www.asbmb.org/asbmb-...
Reposted by Emmanuelle Bignon
📢 Save the date!
Our next workshop by @cecamevents.bsky.social will explore MD database generation, centering in biomacromolecular systems and advancing a FAIR paradigm for MD simulations.
📅 October 15-17, 2025
📍 Lausanne, Switzerland
More details ➡️ bit.ly/3P8ezAs
#MDDB #FAIRdata #openscience
Our next workshop by @cecamevents.bsky.social will explore MD database generation, centering in biomacromolecular systems and advancing a FAIR paradigm for MD simulations.
📅 October 15-17, 2025
📍 Lausanne, Switzerland
More details ➡️ bit.ly/3P8ezAs
#MDDB #FAIRdata #openscience
December 20, 2024 at 1:52 PM
📢 Save the date!
Our next workshop by @cecamevents.bsky.social will explore MD database generation, centering in biomacromolecular systems and advancing a FAIR paradigm for MD simulations.
📅 October 15-17, 2025
📍 Lausanne, Switzerland
More details ➡️ bit.ly/3P8ezAs
#MDDB #FAIRdata #openscience
Our next workshop by @cecamevents.bsky.social will explore MD database generation, centering in biomacromolecular systems and advancing a FAIR paradigm for MD simulations.
📅 October 15-17, 2025
📍 Lausanne, Switzerland
More details ➡️ bit.ly/3P8ezAs
#MDDB #FAIRdata #openscience
Reposted by Emmanuelle Bignon
Open #PhDposition: decipher the mechanisms underlying allostery.
What allows a protein to communicate over many nanometers to regulate its function? How did it evolve? What is the link to protein dynamics?
Join us to study exciting mechanisms by NMR & more.
More info attached.
phd.pages.ista.ac.at
What allows a protein to communicate over many nanometers to regulate its function? How did it evolve? What is the link to protein dynamics?
Join us to study exciting mechanisms by NMR & more.
More info attached.
phd.pages.ista.ac.at
December 22, 2024 at 11:12 AM
Open #PhDposition: decipher the mechanisms underlying allostery.
What allows a protein to communicate over many nanometers to regulate its function? How did it evolve? What is the link to protein dynamics?
Join us to study exciting mechanisms by NMR & more.
More info attached.
phd.pages.ista.ac.at
What allows a protein to communicate over many nanometers to regulate its function? How did it evolve? What is the link to protein dynamics?
Join us to study exciting mechanisms by NMR & more.
More info attached.
phd.pages.ista.ac.at
Reposted by Emmanuelle Bignon
Le LBT se cherche un·e administrateurice systèmes et réseaux. Pour le moment le poste est ouvert en NOEMI (mobilité), donc si vous êtes déjà en poste et souhaitez nous rejoindre, c'est par ici !
mobiliteinterne.cnrs.fr/ords/afip/ow...
mobiliteinterne.cnrs.fr/ords/afip/ow...
a penguin wearing blue overalls and a red bandana says we need you
Alt: a penguin wearing blue overalls and a red bandana says we need you
media.tenor.com
December 4, 2024 at 12:30 PM
Le LBT se cherche un·e administrateurice systèmes et réseaux. Pour le moment le poste est ouvert en NOEMI (mobilité), donc si vous êtes déjà en poste et souhaitez nous rejoindre, c'est par ici !
mobiliteinterne.cnrs.fr/ords/afip/ow...
mobiliteinterne.cnrs.fr/ords/afip/ow...
First post here, how exciting!! 🥳
📣💻[JOB OFFER] I am looking for a postdoc with experience in QM/MM, MD and biosystems, and who would be motivated to study the formation mechanisms of oxydative histone modifications. Please share! #compchem #histones #PTM #redox
www.linkedin.com/posts/activi...
📣💻[JOB OFFER] I am looking for a postdoc with experience in QM/MM, MD and biosystems, and who would be motivated to study the formation mechanisms of oxydative histone modifications. Please share! #compchem #histones #PTM #redox
www.linkedin.com/posts/activi...
Emmanuelle Bignon on LinkedIn: Job offer - pdoc CHROM
📢🧬I have a postdoc position open for people with experience using QM/MM on biosystems! Do not hesitate to apply if you're interested in investigating the…
www.linkedin.com
December 19, 2024 at 8:59 AM
First post here, how exciting!! 🥳
📣💻[JOB OFFER] I am looking for a postdoc with experience in QM/MM, MD and biosystems, and who would be motivated to study the formation mechanisms of oxydative histone modifications. Please share! #compchem #histones #PTM #redox
www.linkedin.com/posts/activi...
📣💻[JOB OFFER] I am looking for a postdoc with experience in QM/MM, MD and biosystems, and who would be motivated to study the formation mechanisms of oxydative histone modifications. Please share! #compchem #histones #PTM #redox
www.linkedin.com/posts/activi...