Nogales Lab
@nogaleslab.bsky.social
The Nogales Lab @ UC Berkeley. #CryoEM #Transcription #Microtubules #ChromatinModification Bluesky account managed by lab members.
Delighted to present my trajectory and research to audiences ranging from high school students to researchers at Hong Kong Universities and Science Centers. Special thanks to my local ambassadors Zhoe and Emi for making my visit so special 🥰🥰
November 14, 2025 at 3:24 AM
Delighted to present my trajectory and research to audiences ranging from high school students to researchers at Hong Kong Universities and Science Centers. Special thanks to my local ambassadors Zhoe and Emi for making my visit so special 🥰🥰
An honor and pleasure to be at the @HKLaureatesForum, a “meeting of inspirational minds” gathering @ShawPrize recipients 🏅 and young scientists. Inspirational to hear other laureates and interact with promising researchers curious about the world around them, big 🪐 & small 🧬
November 14, 2025 at 3:24 AM
An honor and pleasure to be at the @HKLaureatesForum, a “meeting of inspirational minds” gathering @ShawPrize recipients 🏅 and young scientists. Inspirational to hear other laureates and interact with promising researchers curious about the world around them, big 🪐 & small 🧬
Thrilled to share our new cryo-ET preprint on astrocytes, a collaboration with @mengmengfu.bsky.social here at @ucberkeleyofficial.bsky.social, revealing the nm-scale cytoskeletal architecture of ramified astrocytes reminiscing in vivo morphology. Check out the cytoskeleton compartmentalization!
Excited to share our preprint on cytoskeletal organization in astrocytes!
biorxiv.org/content/10.110…
Postdoc @mewynne759 looked at microtubules, IFs/GFAP & actin along long elaborate processes.
Wonderful to collaborate w postdoc @dharshinigopal & @NogalesLab on cryo-ET 🤓
1/x
biorxiv.org/content/10.110…
Postdoc @mewynne759 looked at microtubules, IFs/GFAP & actin along long elaborate processes.
Wonderful to collaborate w postdoc @dharshinigopal & @NogalesLab on cryo-ET 🤓
1/x
https://biorxiv.org/content/10.110…
October 13, 2025 at 11:02 PM
Thrilled to share our new cryo-ET preprint on astrocytes, a collaboration with @mengmengfu.bsky.social here at @ucberkeleyofficial.bsky.social, revealing the nm-scale cytoskeletal architecture of ramified astrocytes reminiscing in vivo morphology. Check out the cytoskeleton compartmentalization!
A unique honor to become a Foreign Member of the @royalsociety.org, together with my @ucberkeleyofficial.bsky.social colleague Stuart Russell and old friends like John Briggs, Asia Akhtar, Patrick Cramer or Ruth Lehmann. Learning about great science and science history was a real treat.
July 19, 2025 at 3:54 PM
A unique honor to become a Foreign Member of the @royalsociety.org, together with my @ucberkeleyofficial.bsky.social colleague Stuart Russell and old friends like John Briggs, Asia Akhtar, Patrick Cramer or Ruth Lehmann. Learning about great science and science history was a real treat.
Very grateful to the Menéndez Pelayo International University for awarding me an honorary doctorate last Tuesday, July 8th, in the incomparable setting of the Magdalena Palace (Santander). On Monday I enjoyed a conversation with those interested in my career and science.
July 19, 2025 at 3:50 PM
Very grateful to the Menéndez Pelayo International University for awarding me an honorary doctorate last Tuesday, July 8th, in the incomparable setting of the Magdalena Palace (Santander). On Monday I enjoyed a conversation with those interested in my career and science.
Our work, co-led by @alfredo0712.bsky.social and @nlue8.bsky.social is out in @natsmb.nature.com Shout out to coauthors P.Grob, B. Kaeser, J.Fang, and S. Kassube for their contributions and thanks to the reviewers for the suggestions that led to the final work.
www.nature.com/articles/s41...
Structural insights into transcriptional regulation by the helicase RECQL5 - Nature Structural & Molecular Biology
Florez Ariza and Lue et al. use cryo-electron microscopy to investigate how the RECQL5 helicase regulates transcription. Their structural findings suggest that RECQL5 can modulate RNA polymerase II’s ...
www.nature.com
July 7, 2025 at 10:35 AM
Our work, co-led by @alfredo0712.bsky.social and @nlue8.bsky.social is out in @natsmb.nature.com Shout out to coauthors P.Grob, B. Kaeser, J.Fang, and S. Kassube for their contributions and thanks to the reviewers for the suggestions that led to the final work.
www.nature.com/articles/s41...
So proud of the smashing success of the International Course in Biophysics co-organized with my @berkeleymcb.bsky.social colleague Carlos Bustamante and University of Salamanca @usaloficial.bsky.social
biophysal.org
Course ends with a Keynote from Nobel Laureate Richard Henderson🥇
biophysal.org
Course ends with a Keynote from Nobel Laureate Richard Henderson🥇
BioPhySAL - First Salamanca International Advanced Biophysics and Structural Biology Course
First Summer International Advanced Biophysics and Structural Biology Course. Eva Nogales - Carlos Bustamante.
biophysal.org
July 5, 2025 at 1:59 PM
So proud of the smashing success of the International Course in Biophysics co-organized with my @berkeleymcb.bsky.social colleague Carlos Bustamante and University of Salamanca @usaloficial.bsky.social
biophysal.org
Course ends with a Keynote from Nobel Laureate Richard Henderson🥇
biophysal.org
Course ends with a Keynote from Nobel Laureate Richard Henderson🥇
Yesterday I had the pleasure to visit the Institute for Material Science in Madrid @icmm-csic.bsky.social. Thank you to Dr. Pedro Serana for his invitation to talk about cryo-EM and our latest microtubule studies 🧩🔬🧬
June 24, 2025 at 8:51 PM
Yesterday I had the pleasure to visit the Institute for Material Science in Madrid @icmm-csic.bsky.social. Thank you to Dr. Pedro Serana for his invitation to talk about cryo-EM and our latest microtubule studies 🧩🔬🧬
I spent a wonderful day in the Universidad de Córdoba at an interactive breakfast with faculty and students and giving a science presentation. Lovely to meet its Chancellor, Manuel Torralbo, and my friend and past collaborator Prof. Tina Domínguez-Martín.
June 24, 2025 at 8:48 PM
I spent a wonderful day in the Universidad de Córdoba at an interactive breakfast with faculty and students and giving a science presentation. Lovely to meet its Chancellor, Manuel Torralbo, and my friend and past collaborator Prof. Tina Domínguez-Martín.
It was an absolute pleasure to visit the IBiS, to meet its scientists, interact with its students, and visit beautiful Sevilla 🥰
🟠SCIENCE |
Thank you very much to Prof. Eva Nogales for sharing her outstanding and inspiring science with us. It was an honor to host her at IBiS!
@hhmi.org @unisevilla.bsky.social @csic.es @nogaleslab.bsky.social @csicandalextrem.bsky.social @ucberkeleyofficial.bsky.social
Thank you very much to Prof. Eva Nogales for sharing her outstanding and inspiring science with us. It was an honor to host her at IBiS!
@hhmi.org @unisevilla.bsky.social @csic.es @nogaleslab.bsky.social @csicandalextrem.bsky.social @ucberkeleyofficial.bsky.social
June 24, 2025 at 8:44 PM
It was an absolute pleasure to visit the IBiS, to meet its scientists, interact with its students, and visit beautiful Sevilla 🥰
Excited to have participated in the Third Symposium of Physical Chemistry in the Universidad Autónoma de Madrid @uam.es last week and honored that the Prizes for best student talk and best posters carried my name 🥰☺️
June 24, 2025 at 8:44 PM
Excited to have participated in the Third Symposium of Physical Chemistry in the Universidad Autónoma de Madrid @uam.es last week and honored that the Prizes for best student talk and best posters carried my name 🥰☺️
Que día tan emocionante volver a mi colegio en Colmenar Viejo y recibir el calor de sus profesores y sus alumnos. Gracias por darle mi nombre a vuestra biblioteca! 🥰
June 24, 2025 at 8:43 PM
Que día tan emocionante volver a mi colegio en Colmenar Viejo y recibir el calor de sus profesores y sus alumnos. Gracias por darle mi nombre a vuestra biblioteca! 🥰
Deeply touched and honored by the Universidad Autónoma de Madrid, my alma mater, (@uam.es) making me Doctor Honoris Causa. Thank you to the Department of Physical Chemistry for nominating me for this recognition. It was a memorable day for me and my family👩🎓
June 24, 2025 at 7:53 PM
Deeply touched and honored by the Universidad Autónoma de Madrid, my alma mater, (@uam.es) making me Doctor Honoris Causa. Thank you to the Department of Physical Chemistry for nominating me for this recognition. It was a memorable day for me and my family👩🎓
Like a dream, my name next to that of @isabelallende.com, and to be recognized by Universidad Internacional Menéndez Pelayo UIMP. Soon after, Irene Vallejo @irenevalmore.bsky.social will receive the same honor. I feel proud to be linked to these truly inspiring, talented women! Thank you UIMP!
June 24, 2025 at 5:03 PM
Like a dream, my name next to that of @isabelallende.com, and to be recognized by Universidad Internacional Menéndez Pelayo UIMP. Soon after, Irene Vallejo @irenevalmore.bsky.social will receive the same honor. I feel proud to be linked to these truly inspiring, talented women! Thank you UIMP!
This week our lab had a double celebration: 1) Eva’s election into the @royalsociety.org and 2) Zhenlin’s new job in Southern University of Science and Technology, China. He will be missed but we wish him success and joy in his independent career!
May 23, 2025 at 1:17 AM
This week our lab had a double celebration: 1) Eva’s election into the @royalsociety.org and 2) Zhenlin’s new job in Southern University of Science and Technology, China. He will be missed but we wish him success and joy in his independent career!
Check out our review article on the structural and functional studies of retrotransposon proteins by @akankshathawani.bsky.social together with Kathy Collins' lab.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Structural and biochemical studies of mobile retrotransposon proteins in action
Autonomous non-long-terminal repeat (non-LTR) retrotransposons, including long interspersed elements (LINEs), are mobile genetic elements abundant in …
www.sciencedirect.com
May 8, 2025 at 8:37 PM
Check out our review article on the structural and functional studies of retrotransposon proteins by @akankshathawani.bsky.social together with Kathy Collins' lab.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Check out our lab’s latest work on the regulation of transcription by RECQL5 helicase! This work was co-led by @alfredo0712.bsky.social and @nlue8.bsky.social, with contributions from Patricia Grob, Ben Kaeser, Jie Fang, and Susanne Kassube. 1/7
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Structural insights into transcriptional regulation by the helicase RECQL5
Transcription and its regulation pose a major challenge for genome stability. The helicase RECQL5 has been proposed as an important factor to help safeguard the genome, and is the only member of the h...
www.biorxiv.org
January 31, 2025 at 3:24 AM
Check out our lab’s latest work on the regulation of transcription by RECQL5 helicase! This work was co-led by @alfredo0712.bsky.social and @nlue8.bsky.social, with contributions from Patricia Grob, Ben Kaeser, Jie Fang, and Susanne Kassube. 1/7
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
I encourage you to apply and join us at @ucberkeleyofficial.bsky.social !
Scientific Director, Cal-Cryo. We are looking for an outstanding microscopist to run our cryo-EM facility (two Krioses and an Arctica), increase training, engagement, and collaboration on campus, expand our user base, and join our community of cutting edge cryo-EM researchers. tinyurl.com/ykasna3p
Scientific Director, Cal-Cryo@QB3, UC Berkeley’s Cryo-EM Facility
University of California, Berkeley is hiring. Apply now!
tinyurl.com
January 16, 2025 at 11:11 PM
I encourage you to apply and join us at @ucberkeleyofficial.bsky.social !
Our microtubule team at lunch with @ruizhangmt.bsky.social, who gave a spectacular seminar at UC Berkeley on his work on axonemes
January 12, 2025 at 6:40 PM
Our microtubule team at lunch with @ruizhangmt.bsky.social, who gave a spectacular seminar at UC Berkeley on his work on axonemes
The Cryo-EM: the next 50 years Symposium held yesterday at @ucberkeleyofficial.bsky.social was a smashing success!!
January 12, 2025 at 4:51 PM
The Cryo-EM: the next 50 years Symposium held yesterday at @ucberkeleyofficial.bsky.social was a smashing success!!
Work led by graduate student @trinitycookis.bsky.social and coauthors Alexandria Lydecker, @paulsauer.bsky.social, and @kasinath-lab.bsky.social is out today where we looked at the inhibition of PRC2 by histone PTMs associated with regions of active transcription.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Structural basis for the inhibition of PRC2 by active transcription histone posttranslational modifications - Nature Structural & Molecular Biology
Structures reveal that histone H3K36me3 and H3K4me3 modifications reduce Polycomb repressive complex 2 (PRC2) function through the inhibition of histone tail engagement and antagonistic binding to the...
www.nature.com
January 8, 2025 at 1:36 AM
Work led by graduate student @trinitycookis.bsky.social and coauthors Alexandria Lydecker, @paulsauer.bsky.social, and @kasinath-lab.bsky.social is out today where we looked at the inhibition of PRC2 by histone PTMs associated with regions of active transcription.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Nogales Lab
El #CSIC concede su Medalla Extraordinaria al Mérito Científico a la biofísica española Eva Nogales, pionera en el uso de criomicroscopía electrónica para visualizar funciones vitales de los componentes moleculares de las células del cuerpo.
¡Enhorabuena!
https://bit.ly/4gsh3W7
¡Enhorabuena!
https://bit.ly/4gsh3W7
December 12, 2024 at 8:01 PM
El #CSIC concede su Medalla Extraordinaria al Mérito Científico a la biofísica española Eva Nogales, pionera en el uso de criomicroscopía electrónica para visualizar funciones vitales de los componentes moleculares de las células del cuerpo.
¡Enhorabuena!
https://bit.ly/4gsh3W7
¡Enhorabuena!
https://bit.ly/4gsh3W7
Miles de gracias a la Universidad Carlos III de Madrid por un acto inolvidable durante mi investidura como Doctora Honoris Causa. Es un orgullo, un gran honor, ser un miembro de su grupo de doctores. Con ilusión por trabajar con ellos en el futuro.
@uc3m.es
@uc3m.es
December 20, 2024 at 7:45 PM
Miles de gracias a la Universidad Carlos III de Madrid por un acto inolvidable durante mi investidura como Doctora Honoris Causa. Es un orgullo, un gran honor, ser un miembro de su grupo de doctores. Con ilusión por trabajar con ellos en el futuro.
@uc3m.es
@uc3m.es
Reposted by Nogales Lab
Eva Nogales received today a big Spanish prize ! The CSIC medal of excellence! So well deserved!
December 17, 2024 at 4:30 PM
Eva Nogales received today a big Spanish prize ! The CSIC medal of excellence! So well deserved!
Reposted by Nogales Lab
The registration deadline for the 1st 'Salamanca International Course on Advanced Biophysics and Structural Biology' at @usaloficial.bsky.social from 30 June to 5 July 2025, ends next Sunday.
Organised by Profs. Carlos Bustamante and
@nogaleslab.bsky.social (CNB-CSIC JAE Chair).
biophysal.org
Organised by Profs. Carlos Bustamante and
@nogaleslab.bsky.social (CNB-CSIC JAE Chair).
biophysal.org
December 13, 2024 at 10:20 AM
The registration deadline for the 1st 'Salamanca International Course on Advanced Biophysics and Structural Biology' at @usaloficial.bsky.social from 30 June to 5 July 2025, ends next Sunday.
Organised by Profs. Carlos Bustamante and
@nogaleslab.bsky.social (CNB-CSIC JAE Chair).
biophysal.org
Organised by Profs. Carlos Bustamante and
@nogaleslab.bsky.social (CNB-CSIC JAE Chair).
biophysal.org