Elaine Sanij
@elainesanij.bsky.social
Cancer Biologist, Lab Head @SVIResearch, Victorian Cancer Agency Research Fellow, Senior Research Fellow @PeterMacRes, Adjunct A/Prof @MonashUni, Views Own
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Elaine Sanij
@elainesanij.bsky.social
· Jan 22
Local nucleolar surveillance mechanisms maintain rDNA stability
The nucleoli are subdomains of the nucleus that form around actively transcribed ribosomal RNA (rRNA) genes. The highly repetitive and transcribed nature of the rRNA genes (rDNA) by RNA polymerase I (...
www.biorxiv.org
1)🚨 Excited to share the first preprint from my lab
at SVI as it celebrates 4 years! 🎉 This work defines local surveillance mechanisms within the nucleoli that activate the DNA damage response (DDR) when DNA damage occurs at rRNA genes (rDNA). www.biorxiv.org/content/10.1...
at SVI as it celebrates 4 years! 🎉 This work defines local surveillance mechanisms within the nucleoli that activate the DNA damage response (DDR) when DNA damage occurs at rRNA genes (rDNA). www.biorxiv.org/content/10.1...
Ribosome Biogenesis and Function in Cancer: From Mechanisms to Therapy
#cancerresearch
A comprehensive review by PhD student Kezia Gitareja as part of a special issue www.mdpi.com/3428496
#cancerresearch
A comprehensive review by PhD student Kezia Gitareja as part of a special issue www.mdpi.com/3428496
August 2, 2025 at 12:11 AM
Ribosome Biogenesis and Function in Cancer: From Mechanisms to Therapy
#cancerresearch
A comprehensive review by PhD student Kezia Gitareja as part of a special issue www.mdpi.com/3428496
#cancerresearch
A comprehensive review by PhD student Kezia Gitareja as part of a special issue www.mdpi.com/3428496
Reposted by Elaine Sanij
Register for the Australian Cell Cycle, DNA Repair & Telomere Meeting in beautiful Melbourne October 19-22, 2025. Plenty of slots for selected abstracts and posters. High praise last time from Piotr Sicinski: "en par with a Gordon conference for science and interaction"
www.australiancellcycle.org
www.australiancellcycle.org
Australian Cell Cycle, DNA repair and Telomere Meeting
October 20-22, 2025
www.australiancellcycle.org
July 22, 2025 at 10:42 AM
Register for the Australian Cell Cycle, DNA Repair & Telomere Meeting in beautiful Melbourne October 19-22, 2025. Plenty of slots for selected abstracts and posters. High praise last time from Piotr Sicinski: "en par with a Gordon conference for science and interaction"
www.australiancellcycle.org
www.australiancellcycle.org
Reposted by Elaine Sanij
Single-cell analysis reveals the extent of genome doubling in ovarian cancer, its variability and its role in enabling tumours to evade the immune system
go.nature.com/4kJLAjZ
go.nature.com/4kJLAjZ
Genome doubling fuels ovarian cancer evolution and immune dysregulation
Single-cell analysis reveals the extent of genome doubling in ovarian cancer, its variability and its role in enabling tumours to evade the immune system.
go.nature.com
July 17, 2025 at 8:14 AM
Single-cell analysis reveals the extent of genome doubling in ovarian cancer, its variability and its role in enabling tumours to evade the immune system
go.nature.com/4kJLAjZ
go.nature.com/4kJLAjZ
Reposted by Elaine Sanij
Applications for this position will close on Friday 30 June
So if you or anyone you know might be interested in applying, time to get your skates on!
So if you or anyone you know might be interested in applying, time to get your skates on!
📢 PostDoc opportunity in our Bioinformatics & Cellular Genomics lab at SVI! 🧬
You’d join a welcoming, supportive, and brilliant team.
Why not spend a few years in Melbourne and be part of something exciting?
Apply here: www.seek.com.au/job/84737876
#ScienceCareers #PostDoc #Bioinformatics
You’d join a welcoming, supportive, and brilliant team.
Why not spend a few years in Melbourne and be part of something exciting?
Apply here: www.seek.com.au/job/84737876
#ScienceCareers #PostDoc #Bioinformatics
Research Officer - Bioinformatics Job in Fitzroy, Melbourne VIC - SEEK
Seeking a Postdoc to develop computational toolkits to enable large-scale studies of single-cell and spatial 'omics and statistical genetics
www.seek.com.au
June 25, 2025 at 1:02 AM
Applications for this position will close on Friday 30 June
So if you or anyone you know might be interested in applying, time to get your skates on!
So if you or anyone you know might be interested in applying, time to get your skates on!
Had the pleasure of serving as an examiner for a PhD thesis defence and visiting the Danish Cancer Institute in Copenhagen 🧬 Two days filled with brilliant science & thoughtful discussion.
Science thrives through connection- across labs, disciplines, and borders. #AcademicTravel
Science thrives through connection- across labs, disciplines, and borders. #AcademicTravel
June 6, 2025 at 5:13 PM
Had the pleasure of serving as an examiner for a PhD thesis defence and visiting the Danish Cancer Institute in Copenhagen 🧬 Two days filled with brilliant science & thoughtful discussion.
Science thrives through connection- across labs, disciplines, and borders. #AcademicTravel
Science thrives through connection- across labs, disciplines, and borders. #AcademicTravel
Reposted by Elaine Sanij
Copying @k8weeks.bsky.social
International Women's Day is the perfect opportunity to connect with #womeninSTEMM and our allies on this platform!
Hello @gregorykj.bsky.social @drmlhalls.bsky.social @louisepurton.bsky.social @karinayaniv.bsky.social @drzoewaller.bsky.social @elainesanij.bsky.social
International Women's Day is the perfect opportunity to connect with #womeninSTEMM and our allies on this platform!
Hello @gregorykj.bsky.social @drmlhalls.bsky.social @louisepurton.bsky.social @karinayaniv.bsky.social @drzoewaller.bsky.social @elainesanij.bsky.social
International Women's Day feels like the perfect opportunity to connect with #womeninSTEMM and our allies on this (still new to me) platform! (1/5)
Hello 👋 @fzmarques.bsky.social @jodieingles27.bsky.social @severinelamon.bsky.social @kimmellor.bsky.social
#IWD2025 #cardiosky
Hello 👋 @fzmarques.bsky.social @jodieingles27.bsky.social @severinelamon.bsky.social @kimmellor.bsky.social
#IWD2025 #cardiosky
March 6, 2025 at 10:17 AM
Copying @k8weeks.bsky.social
International Women's Day is the perfect opportunity to connect with #womeninSTEMM and our allies on this platform!
Hello @gregorykj.bsky.social @drmlhalls.bsky.social @louisepurton.bsky.social @karinayaniv.bsky.social @drzoewaller.bsky.social @elainesanij.bsky.social
International Women's Day is the perfect opportunity to connect with #womeninSTEMM and our allies on this platform!
Hello @gregorykj.bsky.social @drmlhalls.bsky.social @louisepurton.bsky.social @karinayaniv.bsky.social @drzoewaller.bsky.social @elainesanij.bsky.social
Reposted by Elaine Sanij
Join us next week for the Penny Taylor Oration with keynote by Prof Brad Nelson from British Columbia Cancer Research Centre on deciphering and re-engineering the immune response to cancer.
In person and online, register here: www.trybooking.com/events/landi...
In person and online, register here: www.trybooking.com/events/landi...
January 30, 2025 at 4:53 AM
Join us next week for the Penny Taylor Oration with keynote by Prof Brad Nelson from British Columbia Cancer Research Centre on deciphering and re-engineering the immune response to cancer.
In person and online, register here: www.trybooking.com/events/landi...
In person and online, register here: www.trybooking.com/events/landi...
If you see this, quote with flowers from your gallery. 🌿
It’s from a neighbour’s garden and I admire it every time I walk past
It’s from a neighbour’s garden and I admire it every time I walk past
January 26, 2025 at 9:36 AM
If you see this, quote with flowers from your gallery. 🌿
It’s from a neighbour’s garden and I admire it every time I walk past
It’s from a neighbour’s garden and I admire it every time I walk past
Reposted by Elaine Sanij
Thrilled to share the first preprint from @elainesanij.bsky.social lab as my first post on @bsky.app! 🧬🎉 Honored to co-lead this work with Jiachen Xuan and so proud of our amazing team’s efforts to drive and inspire future research! 🙌
1)🚨 Excited to share the first preprint from my lab
at SVI as it celebrates 4 years! 🎉 This work defines local surveillance mechanisms within the nucleoli that activate the DNA damage response (DDR) when DNA damage occurs at rRNA genes (rDNA). www.biorxiv.org/content/10.1...
at SVI as it celebrates 4 years! 🎉 This work defines local surveillance mechanisms within the nucleoli that activate the DNA damage response (DDR) when DNA damage occurs at rRNA genes (rDNA). www.biorxiv.org/content/10.1...
Local nucleolar surveillance mechanisms maintain rDNA stability
The nucleoli are subdomains of the nucleus that form around actively transcribed ribosomal RNA (rRNA) genes. The highly repetitive and transcribed nature of the rRNA genes (rDNA) by RNA polymerase I (...
www.biorxiv.org
January 23, 2025 at 3:26 AM
Thrilled to share the first preprint from @elainesanij.bsky.social lab as my first post on @bsky.app! 🧬🎉 Honored to co-lead this work with Jiachen Xuan and so proud of our amazing team’s efforts to drive and inspire future research! 🙌
1)🚨 Excited to share the first preprint from my lab
at SVI as it celebrates 4 years! 🎉 This work defines local surveillance mechanisms within the nucleoli that activate the DNA damage response (DDR) when DNA damage occurs at rRNA genes (rDNA). www.biorxiv.org/content/10.1...
at SVI as it celebrates 4 years! 🎉 This work defines local surveillance mechanisms within the nucleoli that activate the DNA damage response (DDR) when DNA damage occurs at rRNA genes (rDNA). www.biorxiv.org/content/10.1...
Local nucleolar surveillance mechanisms maintain rDNA stability
The nucleoli are subdomains of the nucleus that form around actively transcribed ribosomal RNA (rRNA) genes. The highly repetitive and transcribed nature of the rRNA genes (rDNA) by RNA polymerase I (...
www.biorxiv.org
January 22, 2025 at 10:00 AM
1)🚨 Excited to share the first preprint from my lab
at SVI as it celebrates 4 years! 🎉 This work defines local surveillance mechanisms within the nucleoli that activate the DNA damage response (DDR) when DNA damage occurs at rRNA genes (rDNA). www.biorxiv.org/content/10.1...
at SVI as it celebrates 4 years! 🎉 This work defines local surveillance mechanisms within the nucleoli that activate the DNA damage response (DDR) when DNA damage occurs at rRNA genes (rDNA). www.biorxiv.org/content/10.1...
Reposted by Elaine Sanij
1/Delighted to announce the newest paper from our lab, “Homologous recombination promotes non-immunogenic mitotic cell death upon DNA damage”, is out today in @naturecellbiology.bsky.social, www.nature.com/articles/s41....
Homologous recombination promotes non-immunogenic mitotic cell death upon DNA damage - Nature Cell Biology
Szmyd et al. show that DNA repair pathways impact whether cells with DNA lesions arrest in mitosis. The formation of homologous recombination-driven double Holliday junctions elicits mitotic cell deat...
www.nature.com
January 13, 2025 at 10:12 AM
1/Delighted to announce the newest paper from our lab, “Homologous recombination promotes non-immunogenic mitotic cell death upon DNA damage”, is out today in @naturecellbiology.bsky.social, www.nature.com/articles/s41....
Reposted by Elaine Sanij
Novel AI Tool “Sees” Gene Expression in Tumor Biopsy Images
"SEQUOIA, a linearized transformer model that predicts cancer transcriptomic profiles from whole slide images."
Open access
www.nature.com/articles/s41...
News
www.insideprecisionmedicine.com/topics/oncol...
"SEQUOIA, a linearized transformer model that predicts cancer transcriptomic profiles from whole slide images."
Open access
www.nature.com/articles/s41...
News
www.insideprecisionmedicine.com/topics/oncol...
Digital profiling of gene expression from histology images with linearized attention - Nature Communications
Predicting gene alterations and expression from whole-slide images (WSIs) can be a cost-efficient solution for cancer profiling. Here, the authors develop SEQUOIA, a transformer model with linearised ...
www.nature.com
December 16, 2024 at 9:29 AM
Novel AI Tool “Sees” Gene Expression in Tumor Biopsy Images
"SEQUOIA, a linearized transformer model that predicts cancer transcriptomic profiles from whole slide images."
Open access
www.nature.com/articles/s41...
News
www.insideprecisionmedicine.com/topics/oncol...
"SEQUOIA, a linearized transformer model that predicts cancer transcriptomic profiles from whole slide images."
Open access
www.nature.com/articles/s41...
News
www.insideprecisionmedicine.com/topics/oncol...
Reposted by Elaine Sanij
December 9, 2024 at 8:26 PM
Reposted by Elaine Sanij
Delighted to publish my new molecular animation:
DNA Break Repair by Homologous Recombination
youtu.be/Xe-83tBcxhs
DNA Break Repair by Homologous Recombination
youtu.be/Xe-83tBcxhs
DNA Break Repair by Homologous Recombination (2024) Drew Berry wehi.tv
YouTube video by WEHImovies
youtu.be
December 4, 2024 at 12:07 AM
Delighted to publish my new molecular animation:
DNA Break Repair by Homologous Recombination
youtu.be/Xe-83tBcxhs
DNA Break Repair by Homologous Recombination
youtu.be/Xe-83tBcxhs