Eszter Csibra
ecsibra.bsky.social
Eszter Csibra
@ecsibra.bsky.social
Group leader and lecturer @ U Leeds 🦠 Synthetic biology 🧬 Protein synthesis 🎨 Fluorescence 🧮 Quantitative biology 📈 Data analysis. | 🐦 = eszter_cs | https://www.csibra-lab.com
Pinned
Two PhD positions available in my group:

1) Investigating ribosome biology in V.natriegens by single particle tracking
with @ryanfseipke.bsky.social @aleksponjavic.bsky.social
Deadline 28 February.
www.findaphd.com/phds/project...

1/2
Building a fluorescent toolbox for exploring translation in Vibrio natriegens at University of Leeds on FindAPhD.com
PhD Project - Building a fluorescent toolbox for exploring translation in Vibrio natriegens at University of Leeds, listed on FindAPhD.com
www.findaphd.com
"proteasome-derived defence peptides could provide an untapped source of natural antibiotics..." 🤯

www.nature.com/articles/s41...
Cell-autonomous innate immunity by proteasome-derived defence peptides - Nature
Proteasomal degradation of cellular proteins generate defence peptides constitutively and in response to bacterial infection. Such peptides might provide a source of natural antibiotics that...
www.nature.com
March 12, 2025 at 8:44 PM
Clams as biosensors of water quality 😄
Hardly new info, but BSky should know:

Warsaw's water quality is monitored by eight clams with magnets attached to their shells. If contamination in the water causes the clams to close, the magnets trigger an alarm and shut off the city's water supply.
Thank you, little guardian molluscs.

🧪🌏🚰
March 4, 2025 at 10:31 AM
Reposted by Eszter Csibra
This excellent interactive tutorial on misleading data visualizations explores the idea of a "counter chart" — the graph you draw in response to refute a misleading claims

flowingdata.com/projects/dis...
Defense Against Dishonest Charts
This is a guide to protect ourselves and to preserve what is good about turning data into visual things.
flowingdata.com
February 15, 2025 at 6:48 AM
Reposted by Eszter Csibra
How to "program" living cells.🧫

In 2000, physicists (incl. Michael Elowitz) made bacteria blink on-and-off every 150 minutes. Their experiment, which blended mathematics and wet-lab methods, launched the field of synthetic biology.

Learn how they did it in my first interactive story!
February 16, 2025 at 5:44 PM
Reposted by Eszter Csibra
Out now! We consolidated >600 Dutch yeast and characterised their activity against spoilage yeasts and relevant human and plant pathogens, focusing on yeasts that secrete antifungal proteins. Great resource for biocontrol and beyond.
pubmed.ncbi.nlm.nih.gov/39875071/
February 3, 2025 at 5:05 PM
Reposted by Eszter Csibra
Amazing work from Farren Isaacs team at Yale - reducing E.coli's genetic code down to only using a single stop codon. A 62 codon GRO with lots of potential for applications. www.nature.com/articles/s41...
Engineering a genomically recoded organism with one stop codon - Nature
Ochre, a strain of Escherichia coli engineered to have a single stop codon, enables reassignment of four codons for non-degenerate functions, such as incorporation of non-standard amino acids into pro...
www.nature.com
February 6, 2025 at 10:27 AM
Reposted by Eszter Csibra
#Microbes Saving Lives & Reducing Suffering—led by KenTimmis, this is a call to action for understanding and exploiting microbes & their role in helping humans at the face of current challenges as a global society @microbiotech.bsky.social
enviromicro-journals.onlinelibrary.wiley.com/doi/full/10....
Microbes Saving Lives and Reducing Suffering
Click on the article title to read more.
enviromicro-journals.onlinelibrary.wiley.com
January 23, 2025 at 9:53 AM
Two PhD positions available in my group:

1) Investigating ribosome biology in V.natriegens by single particle tracking
with @ryanfseipke.bsky.social @aleksponjavic.bsky.social
Deadline 28 February.
www.findaphd.com/phds/project...

1/2
Building a fluorescent toolbox for exploring translation in Vibrio natriegens at University of Leeds on FindAPhD.com
PhD Project - Building a fluorescent toolbox for exploring translation in Vibrio natriegens at University of Leeds, listed on FindAPhD.com
www.findaphd.com
February 10, 2025 at 2:31 PM
Reposted by Eszter Csibra
We cannot join #SMPS4 but hot off the press our nanopore work to monitor CAS9 reactivity and its off-target effects. pubs.acs.org/doi/10.1021/...
Solid-State Nanopore Real-Time Assay for Monitoring Cas9 Endonuclease Reactivity
The field of nanopore sensing is now moving beyond nucleic acid sequencing. An exciting avenue is the use of nanopore platforms for the monitoring of biochemical reactions. Biological nanopores have b...
pubs.acs.org
January 20, 2025 at 9:43 AM
Reposted by Eszter Csibra
👋👋 Hi everyone! The Astbury Centre is now on Bluesky. Follow along for updates about exciting Astbury Centre science. For now, we have put together a starter pack of members of the Astbury Centre community.
January 23, 2025 at 2:37 PM
Reposted by Eszter Csibra
Join us Jan. 23, 17:45 for the first 2025 LSN event!
🧬 Designing de novo tRNAs for Genetic Code Expansion
Amir Guppy
🧪 Harnessing synbio tools for solving crucial biotech questions
Dr. Anastasiya Kishkevich

events.humanitix.com/copy-of-lond...
London SynBio Network 6
London SynBio afterwork talks and networking event on Thursday 12th of December
events.humanitix.com
January 10, 2025 at 2:15 PM
Happy New Year everyone. Just a reminder that there are 3 days left to apply for a BBSRC-funded PhD position with myself and Julie Aspden on ribosome synthetic biology!
Looking for a PhD in molecular/synthetic biology?
Interested in RNA, protein synthesis or molecular machines?

Currently advertising a BBSRC-funded PhD position on engineering novel methods for ribosome control.

Details below. Please don't hesitate to get in touch if you'd like to know more.
January 2, 2025 at 6:54 PM
Reposted by Eszter Csibra
Nominations for the 2025 Dorothy Bishop Award are now open!
Nominations for the 2025 Dorothy Bishop Award are now open! | UK Reproducibility Network
www.ukrn.org
December 14, 2024 at 8:53 PM
Thoroughly enjoyed Next-Gen Synthetic Biology #NGSB24 in Ghent.

A special blend of incredible speakers and laid back forum to chat science.

Halfway home with a head buzzing with ideas and a lengthy reading list for next week.👩‍🔬📚

Thanks to the organisers! @vibtrainconf.bsky.social
December 11, 2024 at 9:27 PM
Reposted by Eszter Csibra
I'm writing up a brief history of the tidyverse? What do you want to know about it? #rstats
November 25, 2024 at 3:24 PM
Looking for a PhD in molecular/synthetic biology?
Interested in RNA, protein synthesis or molecular machines?

Currently advertising a BBSRC-funded PhD position on engineering novel methods for ribosome control.

Details below. Please don't hesitate to get in touch if you'd like to know more.
December 8, 2024 at 2:22 PM
Delighted to find, as a recent cat parent, that our cats are promising scientists. Here is Woody demonstrating that cats are non-Newtonian liquids… kind of.

He will write up his findings as soon as nap time is over. Maybe.
December 8, 2024 at 2:03 PM
Reposted by Eszter Csibra
Join us Dec. 12, 17:45 for the final LSN event of 2024! 🧬

⏭️ Directed evolution of molecular chaperones towards aggregation-prone proteins
ComeStellio

🏥 Engaging cancer patients on their attitudes towards microbiome engineering
@kimberleyaowen.bsky.social

events.humanitix.com/london-synbi...
London SynBio Network 5
London SynBio afterwork talks and networking event on Thursday 12th of December
events.humanitix.com
December 6, 2024 at 1:35 PM
Reposted by Eszter Csibra
Late registration for Gogec is now open till 21 Dec. Looking forward to seeing many of you (and your projects) there! Register at the link ⬇️

tally.so/r/wzzAX1
Gogec 2025 Team Registration
Made with Tally, the simplest way to create forms.
tally.so
December 1, 2024 at 3:06 PM
Reposted by Eszter Csibra
📰 Hot off the press at @naturecomms.bsky.social:
RNA language models predict mutations that improve RNA function
www.nature.com/articles/s41...

Congrats to @kshulgina.bsky.social @jhdcate.bsky.social and coauthors on a great C-GEM + @innovativegenomics.bsky.social collaboration! #NSFfunded #RNAsky
December 5, 2024 at 10:58 PM
Time for a proper intro: 👋 I am a group leader @ Leeds, focused on the study and engineering of translation control in bacteria.

Our interests span 🦠 Synthetic biology 🧬 Protein synthesis 🎨 Fluorescence 🧮 Quantitative biology and 📈 Data analysis.

Lots going on over the next few weeks, stay tuned!
November 19, 2024 at 5:38 PM
Reposted by Eszter Csibra
Exciting post doc opportunity: we are seeking a post doc to work with us and @ProfTomEllis on large DNA engineering in mammalian cells funded by @ChanZuckerberg.
Come and join us at @ImperialChemEng!
Apply at the link below:
www.imperial.ac.uk/jobs/search-...
November 13, 2024 at 9:21 PM
Reposted by Eszter Csibra
Started creating a synthetic biology starter pack. Still missing many so reply here if I forgot you or someone else.
go.bsky.app/SjfpxTK #synbio
November 12, 2024 at 12:30 AM
@calin.bsky.social Great start to the synthetic biology starter pack list .. Would you mind adding me?
November 13, 2024 at 1:50 PM