Rama Bhatia
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drramabht.bsky.social
Rama Bhatia
@drramabht.bsky.social
Postdoctoral Research Fellow in van Houte Lab @uniofexeter.bsky.social| Enthusiastic about microbial evolution, phages and defence systems | Crochet lover 🧶| She\Her| 🇮🇳🇬🇧

https://sites.exeter.ac.uk/multidefence/

https://priaan.etsy.com
Reposted by Rama Bhatia
New pre-print www.biorxiv.org/content/10.1...
Plasmid-dependent phage (PDPs) are ubiquitous, but the selective pressures that they impose on plasmids are not well understood. Project led by Daniel Cazares in collaboration with @brockhurstlab.bsky.social!
#phagesky#microsky
Trade-offs between phage resistance and conjugative ability shape the ecological and evolutionary response of a multidrug resistance plasmid to plasmid-dependent phage
Phage therapy is a promising alternative to antibiotics to treat multidrug resistant infections. Plasmid dependent phages (PDPs) are particularly attractive as therapeutics because they can both kill ...
www.biorxiv.org
October 9, 2025 at 10:07 AM
Reposted by Rama Bhatia
🚨 Call for Abstracts! 🚨
Exeter Microbial Genomics Early Careers Symposium 🦠🧬

Present your work, chair a session, win prizes & network!
📅 12 Nov
📍 Penryn Campus
⏰ Submit TODAY by 5pm 👉 linktr.ee/microbesng

#MicrobialGenomics #ECR #MNGPopUp
Organised with @drramabht.bsky.social @exeter.ac.uk
October 9, 2025 at 10:30 AM
Reposted by Rama Bhatia
Scientists have developed a new gene-editing approach that reprograms pathogens to stop producing toxins and instead make a helpful molecule. cen.acs.org/biological-c...

#CRISPR #geneediting #MolecularBiology #MolBiol #microsky
CRISPR system reprograms bacteria to disarm deadly toxin
Gene-editing technique disables Shiga toxin genes in <i>E. coli</i>
cen.acs.org
July 30, 2025 at 8:46 PM
Reposted by Rama Bhatia
very stimulating blog post for all those who are interested in phylogenetic trees and their construction (without being experts themselves) 👇 great weekend read!
thx andrew @andrewjroger.bsky.social for pointing this out🙏
#MicroSky
July 11, 2025 at 1:19 PM
Reposted by Rama Bhatia
📢 The full #Biofilms11 programme is now available and is packed with groundbreaking content that will spark collaboration and inspire new ideas💡

🗓️ Join @ukbiofilms.bsky.social and @microbiologysociety.org from 13-15 May 2025 in Cardiff ➡️ tinyurl.com/2karbnht

#biofilms #biofilm #MicroSky
Biofilms 11
tinyurl.com
April 3, 2025 at 9:29 AM
Reposted by Rama Bhatia
We also have a couple of poster presentations today 255 from @drramabht.bsky.social, 282 from @anna-k-richmond.bsky.social, 062 from Meg Llewellyn and 068 from Jasmine Thomas-Campbell. All cool stuff about defence systems!
April 2, 2025 at 12:34 PM
Reposted by Rama Bhatia
At Poster 092 today! Loss of quorum sensing and a promoter region mutation in lung-like environments
April 1, 2025 at 8:28 AM
Reposted by Rama Bhatia
@brockhurstlab.bsky.social giving a talk about eco-evolutionary mechanisms of AMR in the AMR session at #Microbio25
April 1, 2025 at 10:54 AM
Reposted by Rama Bhatia
Poster A097 tomorrow at #Microbio25!
Presenting a poster at #Microbio25 today/tomorrow. Come for a chat about defence hotspots in Pseudomonas phage!
March 31, 2025 at 8:07 PM
Reposted by Rama Bhatia
A reminder that there just a few days left to apply to work with us as a post doc on DETECTIVE-II. MRC funded project to work on genomics and metagenomics of AMR in China and the UK

edzz.fa.em3.oraclecloud.com/hcmUI/Candid...
Research Fellow - Department of Microbes, Infection and Microbiomes - 104952 - Grade 7
To take a lead role in the development and delivery of an MRC funded UK-China research network on antimicrobial resistance epidemiology
edzz.fa.em3.oraclecloud.com
December 10, 2024 at 11:15 AM
Reposted by Rama Bhatia
glad to be here!
November 17, 2024 at 11:40 PM
Reposted by Rama Bhatia
This is a truly incredible resource for anyone working on bacterial genomics. I'm struggling to assemble and organise 1,000 bacterial genomes, and I can’t even begin to fathom handling 2.4 million 🤯
Latest data from AllTheBacteria described in our updated preprint. All illumina WGS bacterial+archaeal sequence data to Aug 2024 consistently assembled, QC, and now AMR profiling. That's 2.4 million genomes. Gene annotations almost done , coming next. Please use!

www.biorxiv.org/content/10.1...
AllTheBacteria - all bacterial genomes assembled, available and searchable
The bacterial sequence data publicly available at the global DNA archives is a vast source of information on the evolution of bacteria and their mobile elements. However, most of it is either unassemb...
www.biorxiv.org
November 15, 2024 at 9:00 PM
Reposted by Rama Bhatia
PhD studentship alert!! Two projects available with me fully funded by BBSRC

This one is a collaboration with Dr Michelle Buckner
warwick.ac.uk/fac/cross_fa...

And this one a collaboration with @overtonlab.bsky.social warwick.ac.uk/fac/cross_fa...

Both will be lots of fun! Come & join us 😃
Professor Jessica Blair
Professor Jessica Blair
warwick.ac.uk
November 15, 2024 at 2:57 PM
Reposted by Rama Bhatia
Incredible graphic - the myriad of ways that bacteria defend themselves against antibiotics.

14 resistance mechanisms, summarised by Idan Yelin & Roy Kishony in Cell

www.sciencedirect.com/science/arti...
November 13, 2024 at 12:46 PM
Happy to be featured in the GW4Alliance Newsletter this month!

us6.campaign-archive.com?u=bfba6544e4...
💊GW4 AMR Alliance Newsletter - October 2024
For more details, read the full article by clicking the link below.
us6.campaign-archive.com
October 24, 2024 at 5:25 PM
Reposted by Rama Bhatia
🚨 The Whelan lab is hiring! 🚨 We're looking for a Research Assistant to join our lab at U of Manchester. We're seeking someone with experience in microbiology & microbiome to support our growing group. Note this isn't a postdoc role (though keep 👀 for those announcements soon!) #Microsky 🧪 🧬 💻
Research Assistant - Impact Of Microbe-Pathogen Interactions On The Health Of Individuals With Cystic Fibrosis:Oxford Road
www.jobs.manchester.ac.uk
September 24, 2024 at 8:04 AM
Reposted by Rama Bhatia
Are you a researcher with an interest in #microbiology, #ecology and #evolution? Join our upcoming scientific discussion meeting on the topic of microbial immune systems: ow.ly/fcKR50S89xA
June 5, 2024 at 3:02 PM
Reposted by Rama Bhatia
Please share: Funded PhD project on the ecology and evolution of antibiotic resistance 🦠🧬🫁 at Queen’s University Belfast.
Application deadline: 21 June
Please 📧 me with any questions, happy to chat!

www.findaphd.com/phds/project...
How do interactions in the microbiome shape the evolution of antibiotic resistance in bacterial pathogens? at Queen’s University Belfast on FindAPhD.com
PhD Project - How do interactions in the microbiome shape the evolution of antibiotic resistance in bacterial pathogens? at Queen’s University Belfast, listed on FindAPhD.com
www.findaphd.com
May 21, 2024 at 12:55 PM
Wohoo 🎉 🎉Many Congratulations James!!!
Happy to announce that from August 1st I will be taking up the position of Head of the Department of Evolution, Ecology and Behaviour at the University of Liverpool. Exciting times.

www.liverpool.ac.uk/infection-ve...
Evolution, Ecology and Behaviour - Institute of Infection, Veterinary and Ecological Sciences - University of Liverpool
www.liverpool.ac.uk
May 3, 2024 at 12:05 PM
Reposted by Rama Bhatia
SMBE pangenomes meeting details
Dates: 26-28th November 2024.
Location: National Museum of Nature and Science, Ueno Park, Tokyo, Japan.
Abstract submission: 1st June-31st August.
Registration: 1st July-31st October.
See the updated website: smbepangenomes.bacpop.org
May 1, 2024 at 9:11 AM
Reposted by Rama Bhatia
Thrilled to share our new article now out in Nature Reviews Microbiology! We review how bacterial #AMR evolves within patients during #antibiotic therapy, highlighting the complexity of the problem and how to improve understanding in future work. 1/7 #MicroSky
www.nature.com/articles/s41...
Ecological and evolutionary mechanisms driving within-patient emergence of antimicrobial resistance - Nature Reviews Microbiology
In this Review, Shepherd, Brockhurst and colleagues explore the clinical evidence in support of four major ecological and evolutionary mechanisms of within-patient antimicrobial resistance emergence i...
www.nature.com
May 1, 2024 at 10:35 AM
All set for the Pangenomics course by @jomcinerney.bsky.social @physaliacourses.bsky.social
Excited and looking forward to learning a lot from the expert himself!!!
April 15, 2024 at 9:56 AM
Reposted by Rama Bhatia
Using phage therapy to resensitize P aeruginosa to antibiotics in murine lung infection, featuring @mermanchester.bsky.social’s Rosanna Wright, led by Jo Fothergill www.nature.com/articles/s41...
March 28, 2024 at 4:41 PM
Reposted by Rama Bhatia
Excited to share that our official website is now live 🎉🎉 Find out more about our team and our exciting research here sites.exeter.ac.uk/multidefence/
About our project
Multi-layered bacterial genome defences: linking molecular mechanisms to bacteria-MGE conflicts in single cells, populations, and communities. Resistance to antibiotics (known as antimicrobial resista...
sites.exeter.ac.uk
March 26, 2024 at 3:00 PM
Congratulations Matt!!! Wish I could be there to celebrate your success. Hopefully will see you soon :)
Big congratulations to my very 1st PhD student @kelbrick.bsky.social who passed his PhD viva today with flying colours!🔥Was a pleasure co-parenting with @jpjhall.bsky.social 🥳
March 14, 2024 at 8:37 AM