Dan Nasko
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dnasko.bsky.social
Dan Nasko
@dnasko.bsky.social
Dog dad. I work at PacBio.
Reposted by Dan Nasko
Do you love phage? I have an opening for a postdoc in my lab at the University of South Florida College of Marine Science (@cmarinescience.bsky.social) looking at interactions between marine phage and iron, which is an important limiting trace metal in the oceans (1/5) 🧵#phagesky 🦠🌊
August 1, 2025 at 1:45 PM
Reposted by Dan Nasko
Today's large-scale termination of grants building on months of attacks on experts, expertise, data, and programs reveal the essence of this administration's priorities: dismantling America's innovation-driven economy.

We face a tipping point for science & society.
substack.com/home/post/p-...
A Tipping Point For Science and Society
To confront attacks on experts, expertise, and the rule of law, we must recommit to supporting an independent science and medical research infrastructure.
substack.com
May 16, 2025 at 12:40 AM
Reposted by Dan Nasko
Great talk today by @treangen.bsky.social from Rice University on the advantages of @pacbio.bsky.social #longread #hifi for #microbiome and #metagenomics research + assembly of the great horned owl.
May 15, 2025 at 8:26 PM
Reposted by Dan Nasko
After stops in Danang and Athens, the #PacBioPRISM global tour has arrived in San Francisco! 🇺🇸

We kicked off Day 1 with 25 years of #PacBio innovation and a powerful keynote from Sean Baumstark on resilience, purpose & living beyond limits. We’re just getting started!
May 7, 2025 at 6:26 PM
Reposted by Dan Nasko
It’s the last day for the booths at #APHL! Be sure to come see @pacbio.bsky.social and chat about our new Vega bentchtop sequencer, bringing high accuracy long reads to your public health endeavors. #longreads #microbiology #microbiome #metagenomics
May 7, 2025 at 3:39 PM
Reposted by Dan Nasko
Berry Genomics is transforming single-gene disorder testing in China with #HiFisequencing. Their Thalassemia assay has boosted diagnosis rates and is now powered by the #Vega system.

Read the full story: bit.ly/4iOussj

#PacBio #ClinicalGenomics
May 7, 2025 at 3:06 PM
Reposted by Dan Nasko
Emily Farrow from Children’s Mercy Hospital is the first speaker on day 2 of @pacbio.bsky.social PRISM SF.
May 7, 2025 at 3:46 PM
Reposted by Dan Nasko
I just released a new preprint! The manuscript describes SVTopo, a software tool that enhances visualization of complex SVs using HiFi data: www.biorxiv.org/content/10.1.... Here’s a summary of the results:
Complex structural variant visualization with SVTopo
Structural variants are genomic variants that impact at least 50 nucleotides and can play major roles in diversity and human health. Many structural variants are complex multi-breakpoint rearrangement...
www.biorxiv.org
April 22, 2025 at 2:21 PM
Reposted by Dan Nasko
Exciting things ahead at #AACR25! Join the #PacBio spotlight session to see how long-read sequencing is unlocking cancer variants missed by other technologies. Don’t miss out on this chance to explore the future of cancer genomics.

Details: bit.ly/4icu5rh
April 10, 2025 at 9:55 PM
Reposted by Dan Nasko
Great to see that sawfish, our new HiFi SV caller, is accepted for publication in Bioinformatics! Sawfish emphasizes local haplotype modeling to improve SV representation and genotyping in both single and joint-sample analysis. Advance-access article now available: (1/n)

doi.org/10.1093/bioi...
Sawfish: Improving long-read structural variant discovery and genotyping with local haplotype modeling
AbstractMotivation. Structural variants (SVs) play an important role in evolutionary and functional genomics but are challenging to characterize. High-accu
doi.org
April 10, 2025 at 3:41 PM
Reposted by Dan Nasko
Come and meet the @pacbio.bsky.social team and #Vega at @microbiologysociety.org conference! #microbio25
March 31, 2025 at 11:20 AM
Reposted by Dan Nasko
Will be attending #ACMGMtg25 this week, would love to talk to anyone interested in long-read sequencing analyses!
March 19, 2025 at 4:25 AM
Reposted by Dan Nasko
Zelenskyy's character can be judge more directly by how he treats others and whether you think he's protected his country. From what I've seen, he has treated Americans with respect. His attire is to remind people he's at war, not unlike Churchill wearing a siren suit to the White House in 1942.
March 1, 2025 at 1:00 AM
Reposted by Dan Nasko
Many people are unable to separate clothes from character, which is how the fashion industry makes so much money. They sell you on the idea that you can be a certain person by wearing certain clothes. In reality, character is defined by actions, not clothes.
March 1, 2025 at 1:00 AM
Reposted by Dan Nasko
FWIW, it's perhaps worth noting that when Benjamin Franklin visited France between 1776 and 1778 to ask for military support for the then-new-formed United States of America, he wore a coonskin cap. "Proper" French court attire at this time was a powdered wig.
March 1, 2025 at 1:00 AM
Reposted by Dan Nasko
One reason why I think respectability is stupid is because it's often used as a mask. Such judgements are rarely about the clothes themselves, but more often about the bodies beneath them. To wit, no one raised an issue when Elon wore a graphic t-shirt and ball cap to meet the Trump cabinet.
March 1, 2025 at 1:00 AM
Reposted by Dan Nasko
Join #PacBio for A Bright New Day at PAG 2025! Celebrate discoveries driving plant and animal genomics with live music, dinner, cocktails, and networking. Registration and a PAG conference badge are required for entry. 

Register: bit.ly/41DahZl 

#PAG32 
December 19, 2024 at 5:31 PM
Reposted by Dan Nasko
Think carefully before buying a Greenland shark for the holidays. They are, after all, the world’s longest-living vertebrate.
December 14, 2024 at 1:48 AM
Turkey derrick setup complete ✅
Mishka guarding the turkeys ✅
November 28, 2024 at 7:54 PM
Reposted by Dan Nasko
@sedlazeck.bsky.social AMPath24 talk about long reads highlighting TRGT tool by @egor-dolzhenko.bsky.social and @guilhermesena1.bsky.social and others for HiFi sequencing by @pacbio.bsky.social
November 23, 2024 at 7:23 PM
Reposted by Dan Nasko
Find yourself looking for an affordable, reliable, and highly accurate #longread benchtop sequencer? Look no further with Vega 🕺. It's perfect for #microbial genomics applications like #microbiome, #metagenomics, full-length #16S, isolate #WGS, and #viral seq. @pacbio.bsky.social
www.pacb.com/vega/
a man in a suit is standing in a living room in front of a reel to reel tape recorder .
ALT: a man in a suit is standing in a living room in front of a reel to reel tape recorder .
media.tenor.com
November 14, 2024 at 2:16 AM
Reposted by Dan Nasko

If you were interested but missed it: www.pacb.com/wp-content/u...
www.pacb.com
November 13, 2024 at 7:00 PM
Reposted by Dan Nasko
We can see there's already excitement for Vega on Bluesky. ✨ What do you think about the first #PacBio HiFi benchtop system?
November 13, 2024 at 5:46 PM
Reposted by Dan Nasko
This goes hard.
July 21, 2024 at 12:47 AM
Reposted by Dan Nasko
I'm hiring a Senior Software Engineer at PacBio with focus on improving & productizing ML algorithms. You can work remotely from Europe / USA, or local in Menlo Park.

This is a one time chance to join the long-read bioinformatics instrument team.

www.linkedin.com/jobs/view/37...
PacBio hiring Senior Engineer, Software, Machine Learning in Munich, Bavaria, Germany | LinkedIn
Posted 5:08:11 PM. Job Title Senior Engineer, Software, Machine LearningLocation Remote, US or EuropeDescriptionPacBio…See this and similar jobs on LinkedIn.
www.linkedin.com
November 19, 2024 at 9:46 PM