Jeremy Wilkinson
@jewilki.bsky.social
Molecular biology, microbiome, metagenomics, runner, sports, food & drink, camper, OK State & Texas Tech alum, formerly Huttenhower lab at Harvard SPH @hutlab.bsky.social, now microbial genomics segment lead at PacBio @pacbio.bsky.social. Views are my own.
Reposted by Jeremy Wilkinson
Just 5 spots left! Apply for your chance to attend a 2026 genomics conference with flights, hotel, and registration covered. Meet HiFi sequencing experts and take your research further.
Apply now: bit.ly/4oJQxvy
#PacBio #TheresHiFiForThat #HiFisequencing #Conferences
Apply now: bit.ly/4oJQxvy
#PacBio #TheresHiFiForThat #HiFisequencing #Conferences
November 19, 2025 at 7:04 PM
Just 5 spots left! Apply for your chance to attend a 2026 genomics conference with flights, hotel, and registration covered. Meet HiFi sequencing experts and take your research further.
Apply now: bit.ly/4oJQxvy
#PacBio #TheresHiFiForThat #HiFisequencing #Conferences
Apply now: bit.ly/4oJQxvy
#PacBio #TheresHiFiForThat #HiFisequencing #Conferences
Reposted by Jeremy Wilkinson
#Antimicrobial resistance is a global threat but understanding it starts with complete data. #PacBio HiFi reveals more complete plasmids, resistance genes, & mobile elements with high accuracy. Let’s sequence smarter to fight antimicrobial resistance.
🔗 bit.ly/4rgthrd
#AMR
🔗 bit.ly/4rgthrd
#AMR
November 19, 2025 at 10:31 PM
#Antimicrobial resistance is a global threat but understanding it starts with complete data. #PacBio HiFi reveals more complete plasmids, resistance genes, & mobile elements with high accuracy. Let’s sequence smarter to fight antimicrobial resistance.
🔗 bit.ly/4rgthrd
#AMR
🔗 bit.ly/4rgthrd
#AMR
If you’re at #AMPath2025 in Boston stop by the @pacbio.bsky.social booth #843 and say hi. #longread #HiFi
November 13, 2025 at 4:00 PM
If you’re at #AMPath2025 in Boston stop by the @pacbio.bsky.social booth #843 and say hi. #longread #HiFi
Reposted by Jeremy Wilkinson
The 2026 #PacBio Genomics Conference Giveaway is LIVE!
Travel, registration, and hotel on us.
Here’s why showing up matters, straight from Amino Chain’s Jelani Clarke.
👉 Apply here: bit.ly/4oJQxvy
#TheresHiFiForThat #PacBio #Conferences
Travel, registration, and hotel on us.
Here’s why showing up matters, straight from Amino Chain’s Jelani Clarke.
👉 Apply here: bit.ly/4oJQxvy
#TheresHiFiForThat #PacBio #Conferences
October 30, 2025 at 4:08 PM
The 2026 #PacBio Genomics Conference Giveaway is LIVE!
Travel, registration, and hotel on us.
Here’s why showing up matters, straight from Amino Chain’s Jelani Clarke.
👉 Apply here: bit.ly/4oJQxvy
#TheresHiFiForThat #PacBio #Conferences
Travel, registration, and hotel on us.
Here’s why showing up matters, straight from Amino Chain’s Jelani Clarke.
👉 Apply here: bit.ly/4oJQxvy
#TheresHiFiForThat #PacBio #Conferences
I’ll be at AMP. If you’ll be there, let me know and maybe we can catch up.
Join #PacBio at AMP 2025 in Boston! Visit booth #843 to see live Vega demos and learn how #HiFisequencing captures full genes, resolves repeats, detects complex variants, and reveals phasing and methylation.
See the full program here: bit.ly/4oQedyb
#AMPath2025
See the full program here: bit.ly/4oQedyb
#AMPath2025
November 3, 2025 at 6:43 PM
I’ll be at AMP. If you’ll be there, let me know and maybe we can catch up.
We’re at another @zymoresearch.bsky.social Biofestival at Harvard University. Come say hi if you’re here.
@pacbio.bsky.social
@pacbio.bsky.social
October 18, 2025 at 3:56 PM
We’re at another @zymoresearch.bsky.social Biofestival at Harvard University. Come say hi if you’re here.
@pacbio.bsky.social
@pacbio.bsky.social
Reposted by Jeremy Wilkinson
👀 ICYMI: During ASHG, we unveiled the next era of SMRT Cells and our new SPRQ-Nx chemistry on Revio, enabling comprehensive genomes for under $300 at scale. Beta access is now open, and spots are limited.
Read our press release for more details: bit.ly/4o06eyH
#ASHG25 #PacBio #SPRQNx #Revio
Read our press release for more details: bit.ly/4o06eyH
#ASHG25 #PacBio #SPRQNx #Revio
October 17, 2025 at 2:51 PM
👀 ICYMI: During ASHG, we unveiled the next era of SMRT Cells and our new SPRQ-Nx chemistry on Revio, enabling comprehensive genomes for under $300 at scale. Beta access is now open, and spots are limited.
Read our press release for more details: bit.ly/4o06eyH
#ASHG25 #PacBio #SPRQNx #Revio
Read our press release for more details: bit.ly/4o06eyH
#ASHG25 #PacBio #SPRQNx #Revio
Reposted by Jeremy Wilkinson
Our #ASHG25 PacBio Industry Workshop begins in one hour at 12:00pm in Room 153ABC, Level 1!
Join speakers from Genome Institute of Singapore and Johns Hopkins University to celebrate 25 years of genomics, HiFi sequencing advances, and collaborative discoveries.
#PacBio #ASHG #HiFisequencing
Join speakers from Genome Institute of Singapore and Johns Hopkins University to celebrate 25 years of genomics, HiFi sequencing advances, and collaborative discoveries.
#PacBio #ASHG #HiFisequencing
October 17, 2025 at 3:00 PM
Our #ASHG25 PacBio Industry Workshop begins in one hour at 12:00pm in Room 153ABC, Level 1!
Join speakers from Genome Institute of Singapore and Johns Hopkins University to celebrate 25 years of genomics, HiFi sequencing advances, and collaborative discoveries.
#PacBio #ASHG #HiFisequencing
Join speakers from Genome Institute of Singapore and Johns Hopkins University to celebrate 25 years of genomics, HiFi sequencing advances, and collaborative discoveries.
#PacBio #ASHG #HiFisequencing
We’re at the @zymoresearch.bsky.social biofestival at the University of Maryland. Come say hi if you’re here.
@pacbio.bsky.social
@pacbio.bsky.social
October 17, 2025 at 2:08 PM
We’re at the @zymoresearch.bsky.social biofestival at the University of Maryland. Come say hi if you’re here.
@pacbio.bsky.social
@pacbio.bsky.social
Reposted by Jeremy Wilkinson
We are very excited to offer PacBio Long Read Sequencing in @molecularanalysis.bsky.social !
If you are interested, please get in touch: www.gla.ac.uk/colleges/mvl...
You can also save the date - 14 Nov - as we will be hosting reps from PacBio. More details to follow!
If you are interested, please get in touch: www.gla.ac.uk/colleges/mvl...
You can also save the date - 14 Nov - as we will be hosting reps from PacBio. More details to follow!
October 16, 2025 at 11:08 AM
We are very excited to offer PacBio Long Read Sequencing in @molecularanalysis.bsky.social !
If you are interested, please get in touch: www.gla.ac.uk/colleges/mvl...
You can also save the date - 14 Nov - as we will be hosting reps from PacBio. More details to follow!
If you are interested, please get in touch: www.gla.ac.uk/colleges/mvl...
You can also save the date - 14 Nov - as we will be hosting reps from PacBio. More details to follow!
Reposted by Jeremy Wilkinson
Another #metagenome assembly algorithm for #PacBio HiFi data - introducing Alice!
I'll be very interested to see how this performs on some of our trickier datasets.
More broadly, I'm happy to see continual development of tools for long-read #metagenomics.
doi.org/10.1101/2025...
I'll be very interested to see how this performs on some of our trickier datasets.
More broadly, I'm happy to see continual development of tools for long-read #metagenomics.
doi.org/10.1101/2025...
Alice: fast and haplotype-aware assembly of high-fidelity reads based on MSR sketching
We introduce Mapping-friendly Sequence Reduction (MSR) sketches, a sketching method for high-fidelity (HiFi) long reads, and Alice, an as-sembler that operates directly on these sketches. MSR produces...
doi.org
October 15, 2025 at 4:24 PM
Another #metagenome assembly algorithm for #PacBio HiFi data - introducing Alice!
I'll be very interested to see how this performs on some of our trickier datasets.
More broadly, I'm happy to see continual development of tools for long-read #metagenomics.
doi.org/10.1101/2025...
I'll be very interested to see how this performs on some of our trickier datasets.
More broadly, I'm happy to see continual development of tools for long-read #metagenomics.
doi.org/10.1101/2025...
Reposted by Jeremy Wilkinson
South Korea selects PacBio HiFi Technology for National Pangenome Project
https://www.byteseu.com/1453735/
South Korea selects PacBio HiFi Technology for National Pangenome Project October 14, 2025 | Tuesday | News More than 1,000 Korean genomes to be sequenced for global reference standards …
https://www.byteseu.com/1453735/
South Korea selects PacBio HiFi Technology for National Pangenome Project October 14, 2025 | Tuesday | News More than 1,000 Korean genomes to be sequenced for global reference standards …
South Korea selects PacBio HiFi Technology for National Pangenome Project - Bytes Europe
October 14, 2025 | Tuesday | News
www.byteseu.com
October 15, 2025 at 7:13 PM
South Korea selects PacBio HiFi Technology for National Pangenome Project
https://www.byteseu.com/1453735/
South Korea selects PacBio HiFi Technology for National Pangenome Project October 14, 2025 | Tuesday | News More than 1,000 Korean genomes to be sequenced for global reference standards …
https://www.byteseu.com/1453735/
South Korea selects PacBio HiFi Technology for National Pangenome Project October 14, 2025 | Tuesday | News More than 1,000 Korean genomes to be sequenced for global reference standards …
Reposted by Jeremy Wilkinson
Reposted by Jeremy Wilkinson
#PacBio announces major upcoming advances for #Revio and #Vega designed to lower genome costs, expand multiomic capabilities, and support regulated research.
The SPRQ-Nx chemistry, now in beta access, delivers complete genomes for under $300 at scale.
View the press release: bit.ly/4o06eyH
The SPRQ-Nx chemistry, now in beta access, delivers complete genomes for under $300 at scale.
View the press release: bit.ly/4o06eyH
October 14, 2025 at 3:33 PM
#PacBio announces major upcoming advances for #Revio and #Vega designed to lower genome costs, expand multiomic capabilities, and support regulated research.
The SPRQ-Nx chemistry, now in beta access, delivers complete genomes for under $300 at scale.
View the press release: bit.ly/4o06eyH
The SPRQ-Nx chemistry, now in beta access, delivers complete genomes for under $300 at scale.
View the press release: bit.ly/4o06eyH
Reposted by Jeremy Wilkinson
Here are a few highlights:
We first identified a 1.58 Mbp plasmid in an infant gut metagenome thanks to @pacbio.bsky.social sequencing. The average bacterial genome size in these communities is usually less than 5 Mbp so this was curious to us. We then found similar elements in other infants.
We first identified a 1.58 Mbp plasmid in an infant gut metagenome thanks to @pacbio.bsky.social sequencing. The average bacterial genome size in these communities is usually less than 5 Mbp so this was curious to us. We then found similar elements in other infants.
October 1, 2025 at 5:10 AM
Here are a few highlights:
We first identified a 1.58 Mbp plasmid in an infant gut metagenome thanks to @pacbio.bsky.social sequencing. The average bacterial genome size in these communities is usually less than 5 Mbp so this was curious to us. We then found similar elements in other infants.
We first identified a 1.58 Mbp plasmid in an infant gut metagenome thanks to @pacbio.bsky.social sequencing. The average bacterial genome size in these communities is usually less than 5 Mbp so this was curious to us. We then found similar elements in other infants.
Reposted by Jeremy Wilkinson
Most plasmids described in E. coli are small compared to the megaplasmids we identified here! Check out the preprint if you want to learn about these mysterious large elements and their potential functions 🧬. I’m very grateful to have had the opportunity to work on this in @banfieldlab.bsky.social
Megaplasmids associate with Escherichia coli and other Enterobacteriaceae https://www.biorxiv.org/content/10.1101/2025.09.30.679422v1
October 1, 2025 at 5:10 AM
Most plasmids described in E. coli are small compared to the megaplasmids we identified here! Check out the preprint if you want to learn about these mysterious large elements and their potential functions 🧬. I’m very grateful to have had the opportunity to work on this in @banfieldlab.bsky.social
In the latest issue of DDW Journal, I explore how long-read genomics is driving high-resolution microbiome profiling and why precision microbiomics is set to become the next foundational layer in the drug discovery toolkit. 🧬
Read the full article here. 👉 bit.ly/4mq1xwp
#microbiome #longreads
Read the full article here. 👉 bit.ly/4mq1xwp
#microbiome #longreads
DDW Fall 2025 - Drug Discovery World (DDW)
The DDW Fall issue examines why there is a need for a universal pneumococcal vaccine, why China might be the next global biopharma powerhouse and looks at developments in microbiome research and the t...
bit.ly
September 25, 2025 at 12:24 AM
In the latest issue of DDW Journal, I explore how long-read genomics is driving high-resolution microbiome profiling and why precision microbiomics is set to become the next foundational layer in the drug discovery toolkit. 🧬
Read the full article here. 👉 bit.ly/4mq1xwp
#microbiome #longreads
Read the full article here. 👉 bit.ly/4mq1xwp
#microbiome #longreads
Join us tomorrow if you can. Link below to register.
⏰ Last call! The human #microbiome webinar is tomorrow.
See how #PacBio HiFi sequencing delivers clarity with full-length 16S rRNA and shotgun metagenomics, revealing strain-level insights, novel taxa, and functional pathways.
Register now: bit.ly/46wBttB
See how #PacBio HiFi sequencing delivers clarity with full-length 16S rRNA and shotgun metagenomics, revealing strain-level insights, novel taxa, and functional pathways.
Register now: bit.ly/46wBttB
September 24, 2025 at 11:21 PM
Join us tomorrow if you can. Link below to register.
Reposted by Jeremy Wilkinson
Science award? (The Scientist’s Top Innovations 2025) ✅
Design award? (Fast Company’s Innovation by Design 2025) ✅
Sequencer that’s turning heads everywhere? Vega. 🔥
#Vega #PacBio #HiFiSequencing
Design award? (Fast Company’s Innovation by Design 2025) ✅
Sequencer that’s turning heads everywhere? Vega. 🔥
#Vega #PacBio #HiFiSequencing
September 16, 2025 at 3:23 PM
Science award? (The Scientist’s Top Innovations 2025) ✅
Design award? (Fast Company’s Innovation by Design 2025) ✅
Sequencer that’s turning heads everywhere? Vega. 🔥
#Vega #PacBio #HiFiSequencing
Design award? (Fast Company’s Innovation by Design 2025) ✅
Sequencer that’s turning heads everywhere? Vega. 🔥
#Vega #PacBio #HiFiSequencing
Reposted by Jeremy Wilkinson
Microbes may be small, but the discoveries they drive are huge! 🦠
This #InternationalMicroorganismDay, see how #PacBio HiFi sequencing is uncovering microbial mysteries, from mapping hidden HIV-1 reservoirs to revealing novel AMR pathways.
Details here: bit.ly/4mSgPeL
This #InternationalMicroorganismDay, see how #PacBio HiFi sequencing is uncovering microbial mysteries, from mapping hidden HIV-1 reservoirs to revealing novel AMR pathways.
Details here: bit.ly/4mSgPeL
September 17, 2025 at 4:04 PM
Microbes may be small, but the discoveries they drive are huge! 🦠
This #InternationalMicroorganismDay, see how #PacBio HiFi sequencing is uncovering microbial mysteries, from mapping hidden HIV-1 reservoirs to revealing novel AMR pathways.
Details here: bit.ly/4mSgPeL
This #InternationalMicroorganismDay, see how #PacBio HiFi sequencing is uncovering microbial mysteries, from mapping hidden HIV-1 reservoirs to revealing novel AMR pathways.
Details here: bit.ly/4mSgPeL
Reposted by Jeremy Wilkinson
Long and Kelsey just won the 2025 Microbiome SMRT Grant for HiFi shotgun metagenomics!! They will collaborate to optimize PacBio-compatible protocols for gut metagenomics, specifically generating high quality long-read data from IBD patients. Congrats to both! 🎉 🎉 www.pacb.com/blog/2025-mi...
September 17, 2025 at 6:58 PM
Long and Kelsey just won the 2025 Microbiome SMRT Grant for HiFi shotgun metagenomics!! They will collaborate to optimize PacBio-compatible protocols for gut metagenomics, specifically generating high quality long-read data from IBD patients. Congrats to both! 🎉 🎉 www.pacb.com/blog/2025-mi...
Reposted by Jeremy Wilkinson
The 2025 Long-Read Low Pass SMRT Grant for plant + animal sciences is now open! 🌱🐾
Apply to win free PacBio HiFi sequencing for your conservation or agricultural research.
Submit your 100-word proposal today: bit.ly/3IgrReu
#PacBio #SMRTGrant #HiFisequencing
Apply to win free PacBio HiFi sequencing for your conservation or agricultural research.
Submit your 100-word proposal today: bit.ly/3IgrReu
#PacBio #SMRTGrant #HiFisequencing
September 15, 2025 at 8:11 PM
The 2025 Long-Read Low Pass SMRT Grant for plant + animal sciences is now open! 🌱🐾
Apply to win free PacBio HiFi sequencing for your conservation or agricultural research.
Submit your 100-word proposal today: bit.ly/3IgrReu
#PacBio #SMRTGrant #HiFisequencing
Apply to win free PacBio HiFi sequencing for your conservation or agricultural research.
Submit your 100-word proposal today: bit.ly/3IgrReu
#PacBio #SMRTGrant #HiFisequencing
Reposted by Jeremy Wilkinson
Our first PacBio Revio run with over 140Gb average HiFi yield! This was for a pool of 16 human WGS libraries across 8 SMRTcells, giving >20x coverage per sample. We're running these samples as part of the "Genome of Sweden" project 🧬🇸🇪
September 16, 2025 at 9:38 AM
Our first PacBio Revio run with over 140Gb average HiFi yield! This was for a pool of 16 human WGS libraries across 8 SMRTcells, giving >20x coverage per sample. We're running these samples as part of the "Genome of Sweden" project 🧬🇸🇪
Reposted by Jeremy Wilkinson
New #metagenome assembly comparison of PacBio, ONT, and Illumina in human gut #microbiomes.
- "HiFi generated more cMAGs than ONT at every depth with either assembly method"
- "HiFi cMAGs had significantly higher completeness and lower contamination than ONT"
doi.org/10.1016/j.ce...
- "HiFi generated more cMAGs than ONT at every depth with either assembly method"
- "HiFi cMAGs had significantly higher completeness and lower contamination than ONT"
doi.org/10.1016/j.ce...
Redirecting
doi.org
September 10, 2025 at 3:57 PM
New #metagenome assembly comparison of PacBio, ONT, and Illumina in human gut #microbiomes.
- "HiFi generated more cMAGs than ONT at every depth with either assembly method"
- "HiFi cMAGs had significantly higher completeness and lower contamination than ONT"
doi.org/10.1016/j.ce...
- "HiFi generated more cMAGs than ONT at every depth with either assembly method"
- "HiFi cMAGs had significantly higher completeness and lower contamination than ONT"
doi.org/10.1016/j.ce...
So excited to see the results of these impactful human #microbiome studies and what can be accomplished with high accuracy #longread #metagenomics.
Congratulations to the winners and really looking forward to working with you.
Congratulations to the winners and really looking forward to working with you.
We’re thrilled to announce the 2025 Microbiome SMRT Grant winners! 🎉 Four researchers from around the globe will use HiFi sequencing to push the boundaries of metagenomics.
See the awardees and their projects: bit.ly/3IiBrxq
#PacBio #Microbiome #Genomics #SMRTGrant
See the awardees and their projects: bit.ly/3IiBrxq
#PacBio #Microbiome #Genomics #SMRTGrant
September 12, 2025 at 8:04 PM
So excited to see the results of these impactful human #microbiome studies and what can be accomplished with high accuracy #longread #metagenomics.
Congratulations to the winners and really looking forward to working with you.
Congratulations to the winners and really looking forward to working with you.