Researchers have discovered that the SARS-CoV-2 spike protein persists in the brain and skull bone marrow for years after infection, potentially leading to chronic inflammation and neurodegenerative d...

A new study from UC San Francisco researchers indicates that an extended course of Paxlovid, an antiviral medication, may provide significant benefits for some patients suffering from long COVID sympt...

A host of parasitic diseases commonly thought to have been eradicated in the U.S. are infecting a large number of mostly poor, predominantly Black populations in the Mississippi Delta region. Recent p...

Background: The long-term consequences of COVID-19 infection are becoming increasingly evident in recent studies. This repeated cross-sectional study aimed to explore the long-term health and cognitive effects of COVID-19, focusing on how virus variants, vaccination, illness severity, and time since infection impact post-COVID-19 outcomes. Methods: We examined three cohorts of university students (N = 584) and used non-parametric methods to assess correlations of various health and cognitive variables with SARS-CoV-2 infection, COVID-19 severity, vaccination status, time since infection, time since vaccination, and virus variants. Results: Our results suggest that some health and cognitive impairments may persist, with some even appearing to progressively worsen—particularly fatigue in women and memory in men—up to four years post-infection. The data further indicate that the ancestral SARS-CoV-2 variant may have the most significant long-term impact, while the Omicron variant appears to have the least. Interestingly, the severity of the acute illness was not correlated with the variant of SARS-CoV-2. The analysis also revealed that individuals who contracted COVID-19 after vaccination had better health and cognitive outcomes compared to those infected before vaccination. Conclusions: Overall, our results indicate that even in young individuals who predominantly experienced only mild forms of the infection, a gradual decline in health and fitness can occur over a span of four years post-infection. Notably, some negative trends—at least in men—only began to stabilize or even reverse during the fourth year, whereas in women, these trends showed no such improvement. These findings suggest that the long-term public health impacts of COVID-19 may be more severe and affect a much broader population than is commonly assumed.

ObjectiveThis study evaluated the association between acute COVID-19 cases and the number of car crashes with varying COVID-19 vaccination rates, Long COVID rates, and COVID-19 mitigation strategies.B...

A cohort study identified a link between COVID-19 and a faster decline in kidney function, especially following hospitalization, in contrast to pneumonia.

Approximately 40% of participants did not seroconvert or achieve a conservative neutralization threshold post-vaccination. 

This cohort study examines the annual decrease in estimated glomerular filtration rates among adults diagnosed with COVID-19 and pneumonia in Stockholm, Sweden.

Cognitive impairment, colloquially termed “brain fog”, is one of the most prevalent manifestations of post-Covid syndrome and a major contributor to i…

This preprint study has some stunning findings. The short version is that even among those who had COVID but no symptoms, there is tissue damage. When cells die, their contents are released into th…

Earlier today, comedian, actor, and dancer Casey Frey disclosed to that he may have Long COVID to his nearly two million Instagram followers. Frey became a popular public figure after creating videos ...

Much of the NIH-funded research on long COVID has focused on observing and understanding the disease. Some patients and doctors say the research should pivot toward finding new treatments and drugs.

To date, 770 million people worldwide have contracted COVID-19, with many reporting long-term “brain fog”. Concerningly, young adults are both overrep…

Scientists have has pioneered antivirals targeting viral methyltransferases, offering a new strategy for treating RNA and DNA viruses. This breakthrough could complement existing therapies, offering r...