callista yee
@csybio.bsky.social
worm neurobiologist, assistant professor at UBC zoology. loves tater tots, synapses, dpy worms, and transcription factors. she/her. 🏳️🌈🇨🇦 Looking for grad students and postdocs!
Pinned
callista yee
@csybio.bsky.social
· Jun 25
I will be opening my new lab in September at UBC! if you’re coming to #Worm25 and are looking for graduate studies or a postdoc position, let’s meet! Vancouver + worms = perfect vibes. www.zoology.ubc.ca/~yeecs/labsi... Please share! 🙌
Reposted by callista yee
When asked to draw a scientist, school-age kids in the United States are increasingly sketching women, according to a study from 2018.
Read more on #STEMSTEAMDay: https://scim.ag/4qFrPON
Read more on #STEMSTEAMDay: https://scim.ag/4qFrPON
November 8, 2025 at 4:11 PM
When asked to draw a scientist, school-age kids in the United States are increasingly sketching women, according to a study from 2018.
Read more on #STEMSTEAMDay: https://scim.ag/4qFrPON
Read more on #STEMSTEAMDay: https://scim.ag/4qFrPON
Reposted by callista yee
Our new tool for automating the quantification of synapses (or any other fluorescent puncta) in C. elegans is published- please try it out!! journals.plos.org/ploscompbiol...
WormSNAP: A software for fast, accurate, and unbiased detection of fluorescent puncta in C. elegans
Author summary Here we describe software designed to increase the ease, speed and reliability of analyzing images of fluorescently tagged proteins in C. elegans, a microscopic worm proven to be a powe...
journals.plos.org
October 31, 2025 at 10:16 PM
Our new tool for automating the quantification of synapses (or any other fluorescent puncta) in C. elegans is published- please try it out!! journals.plos.org/ploscompbiol...
Reposted by callista yee
Reposted by callista yee
Yes! Contact them and sign this petition here —it’s not just about EDI data! So much personally identifying information for applicants and reviewers will not be protected!
docs.google.com/forms/d/e/1F...
docs.google.com/forms/d/e/1F...
Open Letter to Protect Tri-Council EDI Data
Why do we need urgent action to protect our data?
The mandate of the House of Commons Standing Committee on Science and Research is to review and report on topics relating to science and research in ...
docs.google.com
October 30, 2025 at 11:36 PM
Yes! Contact them and sign this petition here —it’s not just about EDI data! So much personally identifying information for applicants and reviewers will not be protected!
docs.google.com/forms/d/e/1F...
docs.google.com/forms/d/e/1F...
Reposted by callista yee
Canadian researchers should be aware the there is a motion before the Parliamentary Standing Committee on Science and Research to force Tricouncils to hand over disaggregated peer review data on all applications:
Applicant names, profiles, demographics
Reviewers names, profiles, comments, and scores
Applicant names, profiles, demographics
Reviewers names, profiles, comments, and scores
October 30, 2025 at 8:33 PM
Canadian researchers should be aware the there is a motion before the Parliamentary Standing Committee on Science and Research to force Tricouncils to hand over disaggregated peer review data on all applications:
Applicant names, profiles, demographics
Reviewers names, profiles, comments, and scores
Applicant names, profiles, demographics
Reviewers names, profiles, comments, and scores
today in i’m not crying, you’re crying, found some projection slides on unc-52 splicing, old school scicomm right here. so simple. so perfect. #celegans
October 30, 2025 at 6:34 PM
today in i’m not crying, you’re crying, found some projection slides on unc-52 splicing, old school scicomm right here. so simple. so perfect. #celegans
Reposted by callista yee
Single cell whole genome and transcriptome sequencing links somatic mutations to cell identity and ancestry https://www.biorxiv.org/content/10.1101/2025.10.28.685157v1
October 29, 2025 at 11:33 AM
Single cell whole genome and transcriptome sequencing links somatic mutations to cell identity and ancestry https://www.biorxiv.org/content/10.1101/2025.10.28.685157v1
Reposted by callista yee
What does mating look like when you only have a single shot at getting it right?
Very excited to share our work on an almost-invisible female control, rapidly evolving mating recognition systems, and species that break the rules and take over the world. IN MOSQUITOES>
Very excited to share our work on an almost-invisible female control, rapidly evolving mating recognition systems, and species that break the rules and take over the world. IN MOSQUITOES>
October 28, 2025 at 8:57 PM
What does mating look like when you only have a single shot at getting it right?
Very excited to share our work on an almost-invisible female control, rapidly evolving mating recognition systems, and species that break the rules and take over the world. IN MOSQUITOES>
Very excited to share our work on an almost-invisible female control, rapidly evolving mating recognition systems, and species that break the rules and take over the world. IN MOSQUITOES>
legit obsessed with this kumon pumpkin outside the LSC right now
October 27, 2025 at 7:00 PM
legit obsessed with this kumon pumpkin outside the LSC right now
Reposted by callista yee
'Here we find that the sense of touch interacts with nutritional state to modulate lifespan in Caenorhabditis elegans. Worms subjected to dietary restriction are shorter-lived when they perceive tactile stimuli that mimic bacterial food and/or protective soil.'
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Rewarding touch limits lifespan through neural to intestinal signaling | PNAS
In multicellular organisms, sensory perception affects many aspects of behavior and
physiology. Perception of environmental stressors like food sca...
www.pnas.org
October 24, 2025 at 9:44 AM
'Here we find that the sense of touch interacts with nutritional state to modulate lifespan in Caenorhabditis elegans. Worms subjected to dietary restriction are shorter-lived when they perceive tactile stimuli that mimic bacterial food and/or protective soil.'
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Reposted by callista yee
🧪For those of us who do complex collaborations with multiple corresponding authors this is terrible . I suspect it will also hit female authors disproportionately as they tend to have more collaborations across fields…https://www.nature.com/articles/d41586-025-03281-4
Google Scholar tool gives extra credit to first and last authors
Researchers welcome the initiative, but say it doesn’t go far enough to capture the nuance of researcher productivity and impact.
www.nature.com
October 25, 2025 at 7:05 PM
🧪For those of us who do complex collaborations with multiple corresponding authors this is terrible . I suspect it will also hit female authors disproportionately as they tend to have more collaborations across fields…https://www.nature.com/articles/d41586-025-03281-4
had such a lovely day today at SFU. thank you so much @estherverheyen.bsky.social and @lisaj456.bsky.social for hosting me 💫, SFU rules. excellent science, bright trainees, and good vibes.
October 25, 2025 at 3:49 AM
had such a lovely day today at SFU. thank you so much @estherverheyen.bsky.social and @lisaj456.bsky.social for hosting me 💫, SFU rules. excellent science, bright trainees, and good vibes.
Reposted by callista yee
The Cummings Lab is hiring a postdoc to work in the areas of reward and addiction! Please see the ad below:
October 23, 2025 at 6:22 PM
The Cummings Lab is hiring a postdoc to work in the areas of reward and addiction! Please see the ad below:
got to hangout with don today and look what he gifted us…an original print of genetics that had The genetics of Caenorhabditis elegans by Brenner 😭 #celegans 🧪
October 5, 2025 at 4:57 AM
got to hangout with don today and look what he gifted us…an original print of genetics that had The genetics of Caenorhabditis elegans by Brenner 😭 #celegans 🧪
Reposted by callista yee
Hi fellow C. elegans scientists, I've made a few videos that may be of use for new trainees working in worm labs. Hoping to add more in the future, but figured I'd share this resource as is in case it's helpful :)
www.youtube.com/@Workingwith...
www.youtube.com/@Workingwith...
Working with C. elegans
This channel provides clear demonstrations of core C. elegans lab skills, including: recognizing life stages and common phenotypes, picking and manipulating worms, and maintaining healthy cultures. De...
www.youtube.com
October 1, 2025 at 7:20 PM
Hi fellow C. elegans scientists, I've made a few videos that may be of use for new trainees working in worm labs. Hoping to add more in the future, but figured I'd share this resource as is in case it's helpful :)
www.youtube.com/@Workingwith...
www.youtube.com/@Workingwith...
Reposted by callista yee
🚀 Our new paper is out @natmethods.nature.com!
Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells.
🔗 www.nature.com/articles/s41...
🧬 www.addgene.org/John_Ngo/
Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells.
🔗 www.nature.com/articles/s41...
🧬 www.addgene.org/John_Ngo/
September 22, 2025 at 6:27 PM
🚀 Our new paper is out @natmethods.nature.com!
Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells.
🔗 www.nature.com/articles/s41...
🧬 www.addgene.org/John_Ngo/
Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells.
🔗 www.nature.com/articles/s41...
🧬 www.addgene.org/John_Ngo/
1993 gilson pipettes!!! 😭😭😭😭
September 19, 2025 at 3:31 PM
1993 gilson pipettes!!! 😭😭😭😭
if anyone wants a billion cardboard freezer boxes, hmu.
September 18, 2025 at 7:56 PM
if anyone wants a billion cardboard freezer boxes, hmu.
got the keys to my office today - I’m not crying you’re crying
September 9, 2025 at 9:01 PM
got the keys to my office today - I’m not crying you’re crying
Reposted by callista yee
The chromatin remodeller CHD4 controls both nucleosome integrity and transcription factor binding to promote activity of active regulatory elements and to prevent activation of silent enhancers https://www.biorxiv.org/content/10.1101/2025.08.29.672645v1
August 30, 2025 at 7:18 AM
The chromatin remodeller CHD4 controls both nucleosome integrity and transcription factor binding to promote activity of active regulatory elements and to prevent activation of silent enhancers https://www.biorxiv.org/content/10.1101/2025.08.29.672645v1
our department @zoology.ubc.ca has a tenure-track faculty position opening at the level of Assistant Professor of Teaching in the educational stream with a focus on Neuroscience! please share! academicjobsonline.org/ajo/jobs/30389
University of British Columbia, Department of Zoology
Job #AJO30389, Assistant Professor of Teaching- Neuroscience, Department of Zoology, University of British Columbia, Vancouver, British Columbia, CA
academicjobsonline.org
August 26, 2025 at 6:38 PM
our department @zoology.ubc.ca has a tenure-track faculty position opening at the level of Assistant Professor of Teaching in the educational stream with a focus on Neuroscience! please share! academicjobsonline.org/ajo/jobs/30389
Reposted by callista yee
New paper on the role of H3K4me3 at enhancers! We (led by Haoming Yu) used dCas9 epigenome editing to add H3K4me3 to intergenic enhancers. This was (1) sufficient to turn up transcription at open, active regions and (2) has no effect on target gene transcription. genesdev.cshlp.org/content/earl...
H3K4me3 amplifies transcription at intergenic active regulatory elements
A biweekly scientific journal publishing high-quality research in molecular biology and genetics, cancer biology, biochemistry, and related fields
genesdev.cshlp.org
August 20, 2025 at 1:29 AM
New paper on the role of H3K4me3 at enhancers! We (led by Haoming Yu) used dCas9 epigenome editing to add H3K4me3 to intergenic enhancers. This was (1) sufficient to turn up transcription at open, active regions and (2) has no effect on target gene transcription. genesdev.cshlp.org/content/earl...
heck yeah ethan!
Pathway to Independence – an interview with Chee Kiang (Ethan) Ewe.
In this interview, @ethanewe.bsky.social talks about about what drives and excites him, and what he hopes to achieve in his own lab:
journals.biologists.com/dev/article/...
In this interview, @ethanewe.bsky.social talks about about what drives and excites him, and what he hopes to achieve in his own lab:
journals.biologists.com/dev/article/...
August 18, 2025 at 11:17 AM
heck yeah ethan!