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CBM CNRS UPR4301
@cbm-upr4301.bsky.social
Account of the Centre de Biophysique Moléculaire Lab
#ESR #CNRS UPR4301
Reposted by CBM CNRS UPR4301
#CNRSnews 📰 The chemical revolution of the early 20th century was a golden age for painters with the rising number of pigments available. Scientists are scrutinising Robert Delaunay’s colours, especially his purples, in an effort to conserve his works 🎨🖌️

👉 news.cnrs.fr/slideshows/s...
Seeing life in purple
The early 20th-century artist Robert Delaunay began painting at a pivotal moment in art history, namely during the chemical industry revolution, when the number of pigments available on the market increased. Today scientists are trying to solve the mystery of the painter’s colours, his purples in particular. One of the objectives of this research is to generate knowledge essential to conserving the works.
news.cnrs.fr
November 17, 2025 at 7:02 PM
Reposted by CBM CNRS UPR4301
Very happy to share our collaborative project on FAM118 proteins - noncanonical sirtuins that form filaments and process NAD in human and other vertebrate cells.
Filament formation and NAD processing by noncanonical human FAM118 sirtuins
Nature Structural & Molecular Biology - Baretić and Missoury et al. identify vertebrate proteins FAM118B and FAM118A as sirtuins similar to bacterial antiphage enzymes and show that...
rdcu.be
November 17, 2025 at 11:37 AM
Reposted by CBM CNRS UPR4301
Imaginer et préparer le futur afin d’orienter la recherche et les politiques publiques, tel est le but de la prospective. Un exercice périlleux, soulignent les scientifiques. Ingrédients requis : le dialogue entre les disciplines et des modèles robustes répondant aux multiples incertitudes.
Comment la science prépare-t-elle l’avenir ?
lejournal.cnrs.fr
November 15, 2025 at 11:38 PM
Reposted by CBM CNRS UPR4301
De mon côté on m'a confié le micro pour la chronique sciences.

Cette fois j'ai décidé de parler du fonctionnement scandaleux de l'édition scientifique, peu connu en dehors des labos : www.youtube.com/watch?v=Yg2C...

Mais 4 minutes c'est court, alors j'ajoute quelques ressources ci-dessous !
Le beurre, l’argent du beurre et le c*l des chercheurs- La chronique de Tania Louis dans La dernière
YouTube video by Radio Nova
www.youtube.com
November 12, 2025 at 6:37 PM
Reposted by CBM CNRS UPR4301
How much do you know about the chemistry of spices? Test your knowledge of what spice chemicals can do besides seasoning food. cen.acs.org/biological-c... #chemsky 🧪
Quiz: How much do you know about the chemistry of spices?
Test your knowledge of what spice chemicals can do besides seasoning food.
cen.acs.org
November 6, 2025 at 1:13 PM
Reposted by CBM CNRS UPR4301
I'm currently at LCLS in Stanford, anyone got a lead on where I might find a #SynchrotonMug to add to my collection? I know they exist. I've seen pictures!
November 6, 2025 at 7:52 PM
Reposted by CBM CNRS UPR4301
SUMO interactions: the 1st of two reviews which Aanchal (@origichals.bsky.social), El Hadji, and I have recently written on non-covalent interactions of SUMO is now out. The 1st covers interactions with E1, E2, and deSUMOylating enzymes; the 2nd - on interactions with SIMs etc. - will appear soon.
Non-covalent SUMO interactions with (de)conjugation enzymes
SUMOylation – a protein post-translational modification (PTM) related to ubiquitylation – involves the reversible covalent attachment of the small ubiquitin-like modifier (SUMO) to proteins. During th...
portlandpress.com
November 5, 2025 at 1:44 PM
Reposted by CBM CNRS UPR4301
Micrograd: a pedagogical implementation of neural networks using a reverse-mode automatic differentiation engine.

https://hyperdoc.khinsen.net/94FE4-micrograd

I have written this as a real-life example of explorable explanations in HyperDoc.

Feedback welcome at […]
Original post on scholar.social
scholar.social
November 3, 2025 at 1:21 PM
J-10...
a digital clock that says counting down at 00:00
ALT: a digital clock that says counting down at 00:00
media.tenor.com
November 4, 2025 at 6:38 AM
Reposted by CBM CNRS UPR4301
Lipid bilayer thinning near a ubiquitin ligase selects ER membrane proteins for degradation www.biorxiv.org/content/10.1...
Lipid bilayer thinning near a ubiquitin ligase selects ER membrane proteins for degradation
Misfolded or unassembled membrane proteins in the endoplasmic reticulum (ER) are polyubiquitinated, translocated into the cytosol, and degraded by the proteasome, a poorly understood process that is c...
www.biorxiv.org
November 3, 2025 at 3:35 PM
Reposted by CBM CNRS UPR4301
Seeking work in a research group run by an ERC-funded researcher?

You can find more than 145 positions open for application on the #Euraxess website 👉 buff.ly/ROwXHf6

#ChooseEurope #jobs #research
October 25, 2025 at 11:30 AM
Reposted by CBM CNRS UPR4301
I'm a bit late with the customary #MoleDay infographic this year, but better late than never!

The mole makes it easier to describe the huge numbers of atoms, molecules, or ions that participate in chemical reactions.

More in this graphic: www.compoundchem.com/2014/10/23/m...

#ChemSky 🧪
October 23, 2025 at 7:35 PM
Next 2 months will be busy with Thesis Defences at CBM,
save the date for:
03/11 : Anna Novak
05/11 : Clémence Couton
28/11 : Adrien Uguen
01/12 : Sebastian Gfellner
01/12 : Ayoub Medjmedj
10/12 : Chloé Lamelli
15/12 : Lucija Mance
15/12 : Emmanuel Douez
18/12 : Lylia Azzoug
...
🍿
October 20, 2025 at 6:07 AM
Reposted by CBM CNRS UPR4301
La fonction de président du Centre national de la recherche scientifique (CNRS) est déclarée vacante, à compter du 8 février 2026.

➡️ Au JO, publication de l'avis relatif à un appel à candidatures en vue de pourvoir la fonction de président du #CNRS.

📎 www.legifrance.gouv.fr/jorf/id/JORF...

#ESR
October 19, 2025 at 5:18 AM
Reposted by CBM CNRS UPR4301
💫 Celebrate the festival of lights safely, and let the chemistry of joy shine bright!

Wishing you and your loved ones a very Happy Diwali filled with love, light, and laughter. #RSCIndia #ChemSky #Diwali2025
October 17, 2025 at 5:30 AM
Reposted by CBM CNRS UPR4301
📢 Appel à projets générique (AAPG) 2026 de l'ANR : la date de clôture de l’étape 1 est décalée du 14/10/2025 - 17h (heure de Paris) au 15/10/2025 - 17h (heure de Paris).
anr.fr/fr/detail/ca...
October 14, 2025 at 1:33 PM
Recommandations from "Stop treating code like an afterthought: record, share and value it"
media.nature.com/original/mag...
media.nature.com
October 8, 2025 at 7:00 AM
Reposted by CBM CNRS UPR4301
And our last video on antimicrobial peptides in English is now out:
www.canal-u.tv/chaines/cbm/... thanks to @agencerecherche.bsky.social
Antimicrobial peptides | Canal U
How can antimicrobial peptides become an alternative to antibiotics ?
www.canal-u.tv
October 3, 2025 at 6:42 AM
Reposted by CBM CNRS UPR4301
Scientists are turning massive MD data into clear, actionable visuals, from classic 3D to VR—bridging complexity and decision-making. Read more → Frontiers review ↗ #moleculardynamics #visualization 🔬 What do you think?

is.gd/1MefYo
How Scientists Turn Massive Molecular Simulations into Clear, Useful Pictures | Marc Baaden
Ever wondered how scientists make sense of the billions of atoms and mountains of data churned out by molecular simulations? Our latest review in Frontiers in Bioinformatics dives into the art and sci...
is.gd
October 2, 2025 at 10:32 AM
Reposted by CBM CNRS UPR4301
Besoin d’une source fiable pour vos #recherches ?
Canal-U, c’est +50 000 vidéos & podcasts en accès libre produits par +400 universités, instituts & musées, dans +60 disciplines.
👉 Découvrez www.canal-u.tv !
@enseignementsup-recherche.gouv.fr @fondationmsh.bsky.social
#CanalU #ESR #sciences
October 1, 2025 at 7:45 AM
Reposted by CBM CNRS UPR4301
A part of our team at the recent EMBO SUMO conference in La Grande Motte/Montpellier
September 30, 2025 at 9:43 AM
Reposted by CBM CNRS UPR4301
Quelles sont les 1ères traces de vie sur Terre ?

Une synthèse graphique de Claire Marc, écrite par @cnrs-insu.bsky.social avec la précieuse aide d'Isabelle Daniel @lyongeologie.bsky.social

#vulgarisation #SVT

Thread à dérouler ci-dessous :

1/6
September 24, 2025 at 3:05 PM
Reposted by CBM CNRS UPR4301
#ResultatScientifique🔎| Une avancée concernant une nouvelle cible thérapeutique pour le glioblastome, le plus agressif des cancers du cerveau

✍️ Laurent Chatre
📕 Redox Report |
Glioblastome : une découverte scientifique pour mieux comprendre ce cancer agressif
A travers l’utilisation de la porphyrine de manganèse (III) tétrakis (acide 4-benzoïque) (MnTBAP), des scientifiques ont identifié la protéine sulfide:q
buff.ly
September 23, 2025 at 12:26 PM
Reposted by CBM CNRS UPR4301
Experimental verification is increasingly the bottleneck in protein design projects.

In this paper, we develop a new mini-binder screening pipeline based on the microfluidic sizing technique called flow-induced dispersion analysis (FIDA).

doi.org/10.1002/pro....
Screening de novo designed protein binders in unpurified lysate using flow induced dispersion analysis
Computational protein design can create binders against targets of interest, but identifying binders with sufficient affinity still requires biochemical screening of many designs. In this work, we te....
doi.org
September 15, 2025 at 7:51 PM
Reposted by CBM CNRS UPR4301
Sharing once again - and highly recommending - the postdoc positions with Antoni. One of the projects is a collaboration with us and the postdoc will include a sojourn in our lab.
Dear scientific community,

I am looking for two postdoctoral structural biologists to join my group at the Department of Biochemistry, University of Oxford.

my.corehr.com/pls/uoxrecru...

my.corehr.com/pls/uoxrecru...
September 16, 2025 at 5:32 AM