Sam "The Mug Guy" Horrell
@drhorrell.bsky.social
Scientist 🧑🔬, structural biologist 🧬, X-ray Crystallographer 💎, Synchrotron Mug Enthusiast ☕, D&D 🎲 and MTG player 🧙, bird dad to Nori and Kili 🦜🦜
He/Him
He/Him
I'm currently at LCLS in Stanford, anyone got a lead on where I might find a #SynchrotonMug to add to my collection? I know they exist. I've seen pictures!
November 6, 2025 at 7:52 PM
I'm currently at LCLS in Stanford, anyone got a lead on where I might find a #SynchrotonMug to add to my collection? I know they exist. I've seen pictures!
Finally, a detector suitable for the new SynchroGnome beamlines. A giant leap forward in tiny science.
#ROD10atECM #ECM
#ROD10atECM #ECM
August 26, 2025 at 12:16 PM
Finally, a detector suitable for the new SynchroGnome beamlines. A giant leap forward in tiny science.
#ROD10atECM #ECM
#ROD10atECM #ECM
Made it to Poznan for the European Crystallography Meeting. Looking forward to presenting at the Science Slam on Thursday with the help of my cat Rosalind.
#Crystallography #ECM35 #StructuralBiology #ScienceCommunication #SciComm #ScienceSlam
#Crystallography #ECM35 #StructuralBiology #ScienceCommunication #SciComm #ScienceSlam
August 25, 2025 at 10:52 AM
Made it to Poznan for the European Crystallography Meeting. Looking forward to presenting at the Science Slam on Thursday with the help of my cat Rosalind.
#Crystallography #ECM35 #StructuralBiology #ScienceCommunication #SciComm #ScienceSlam
#Crystallography #ECM35 #StructuralBiology #ScienceCommunication #SciComm #ScienceSlam
I don't want to alarm anyone, but I think my electron density might be haunted.
💎👻💀
💎👻💀
August 20, 2025 at 3:47 PM
I don't want to alarm anyone, but I think my electron density might be haunted.
💎👻💀
💎👻💀
Said goodbye to the @dectris.bsky.social Pilatus 6M the other day with one last #DetectorSelfie featuring beamline scientist Sofia.
Collected some data to 0.87 A to give it a proper send off.
Not sure how many images it has taken on I24 but it is very deserving of a rest.
Collected some data to 0.87 A to give it a proper send off.
Not sure how many images it has taken on I24 but it is very deserving of a rest.
August 11, 2025 at 6:02 PM
Said goodbye to the @dectris.bsky.social Pilatus 6M the other day with one last #DetectorSelfie featuring beamline scientist Sofia.
Collected some data to 0.87 A to give it a proper send off.
Not sure how many images it has taken on I24 but it is very deserving of a rest.
Collected some data to 0.87 A to give it a proper send off.
Not sure how many images it has taken on I24 but it is very deserving of a rest.
Protein structure or #Minecraft Creeper?
June 19, 2025 at 9:29 AM
Protein structure or #Minecraft Creeper?
Taking bets on if this is crystalline or not. We'll find out next week on @diamondlightsource.bsky.social's VMXm next week with the help of @adamcrawshaw.bsky.social.
June 13, 2025 at 9:50 AM
Taking bets on if this is crystalline or not. We'll find out next week on @diamondlightsource.bsky.social's VMXm next week with the help of @adamcrawshaw.bsky.social.
The electron microscope can't believe you just said that.
June 5, 2025 at 2:24 PM
The electron microscope can't believe you just said that.
After 2 weeks of antibiotics twice a day Nori (left) now has a clean bill of health.
Kili (right) is clearly pleased about this too.
Kili (right) is clearly pleased about this too.
May 29, 2025 at 4:01 PM
After 2 weeks of antibiotics twice a day Nori (left) now has a clean bill of health.
Kili (right) is clearly pleased about this too.
Kili (right) is clearly pleased about this too.
I was minding my own business watching a music video when suddenly I see @thewarningarmy.bsky.social have managed to crystallise themselves. So I thought I'd see if they diffract, and they do!
#Crystallography #TheWarning #Crystal #Diffraction
#Crystallography #TheWarning #Crystal #Diffraction
May 22, 2025 at 10:37 AM
I was minding my own business watching a music video when suddenly I see @thewarningarmy.bsky.social have managed to crystallise themselves. So I thought I'd see if they diffract, and they do!
#Crystallography #TheWarning #Crystal #Diffraction
#Crystallography #TheWarning #Crystal #Diffraction
If this #crystal space group isn't P3 or P6 I'll eat my #crystallography hat.
It also reminds me of a tiny allen key.
It also reminds me of a tiny allen key.
May 15, 2025 at 10:45 AM
If this #crystal space group isn't P3 or P6 I'll eat my #crystallography hat.
It also reminds me of a tiny allen key.
It also reminds me of a tiny allen key.
Reposted by Sam "The Mug Guy" Horrell
Changes in PDB IDs are coming that will require use of PDBx/mmCIF file format... will you be ready? #MayThe4th
Resources are available to help: www.wwpdb.org/docume...
Resources are available to help: www.wwpdb.org/docume...
May 4, 2025 at 4:12 PM
Changes in PDB IDs are coming that will require use of PDBx/mmCIF file format... will you be ready? #MayThe4th
Resources are available to help: www.wwpdb.org/docume...
Resources are available to help: www.wwpdb.org/docume...
Pretty successful draft at the local game store. Won the event and got a chonky dragon.
#MTG #MagicTheGathering
#MTG #MagicTheGathering
May 2, 2025 at 10:04 PM
Pretty successful draft at the local game store. Won the event and got a chonky dragon.
#MTG #MagicTheGathering
#MTG #MagicTheGathering
Blue copper crystals on a silicon chip.
May 1, 2025 at 3:57 PM
Blue copper crystals on a silicon chip.
New paper out today on a cyclic peptide which interacts with CD59, a protein that inhibits the complement mediated membrane attack complex.
Some cool structural work went into this, modelling the cyclic peptide was an interesting challenge.
onlinelibrary.wiley.com/doi/abs/10.1...
Some cool structural work went into this, modelling the cyclic peptide was an interesting challenge.
onlinelibrary.wiley.com/doi/abs/10.1...
Macrocyclic Peptide Probes for Immunomodulatory Protein CD59: Potent Modulators of Bacterial Toxin Activity and Antibody‐Dependent Cytotoxicity
CD59 is an immunomodulatory cell surface receptor associated with human disease. Despite its importance in complement regulation and bacterial pathogenesis, CD59 remains a challenging therapeutic tar....
onlinelibrary.wiley.com
May 1, 2025 at 2:14 PM
New paper out today on a cyclic peptide which interacts with CD59, a protein that inhibits the complement mediated membrane attack complex.
Some cool structural work went into this, modelling the cyclic peptide was an interesting challenge.
onlinelibrary.wiley.com/doi/abs/10.1...
Some cool structural work went into this, modelling the cyclic peptide was an interesting challenge.
onlinelibrary.wiley.com/doi/abs/10.1...
April 18, 2025 at 2:44 PM
Did someone say protein crystals?
Someone probably said protein crystals.
Someone probably said protein crystals.
April 16, 2025 at 9:37 AM
Did someone say protein crystals?
Someone probably said protein crystals.
Someone probably said protein crystals.
What are the Rolling Stones doing in my electron density?
April 15, 2025 at 2:55 PM
What are the Rolling Stones doing in my electron density?
Do you think it's surprised to see me?
April 15, 2025 at 1:09 PM
Do you think it's surprised to see me?
Classic Isoleucine behaviour
April 15, 2025 at 10:49 AM
Classic Isoleucine behaviour
Reposted by Sam "The Mug Guy" Horrell
A purrfectly normal envelope to have slid under my office door as a Crystallographer.
April 14, 2025 at 9:53 AM
A purrfectly normal envelope to have slid under my office door as a Crystallographer.
Hmm, looks orthorhombic primitive to me.
April 13, 2025 at 2:34 PM
Hmm, looks orthorhombic primitive to me.