Luca Caputo
@capluca.bsky.social
🌈🔬 Biology, Politics, LGBTQ+ and Juventus in random order
#lgbtSTEM #loveislove #finoallafine
Opinions are mine own
He/They
#lgbtSTEM #loveislove #finoallafine
Opinions are mine own
He/They
Pinned
Luca Caputo
@capluca.bsky.social
· Oct 18
Luca Caputo | 500 Queer Scientists
I work to understand how the three-dimensional folding of the genome impacts cell-fate decision, and how during development and in diseases alteration of the 3D genome impact on cell-fate decisions.
500queerscientists.com
First post = short introduction: postdoc studying chromatin biology in skeletal and cardiac muscle (mostly), MDA funded, interested in DEI initiatives, co-founder of QueerScienceSociety of San Diego and former Board Member of @outtoinnovate.bsky.social
500queerscientists.com/luca-caputo/
500queerscientists.com/luca-caputo/
Reposted by Luca Caputo
PSA for people with NIH grant periods starting January 1st (including most NIGMS MIRAs): your RPPR is due Saturday, but they haven’t sent out the usual automated reminders, presumably due to the shutdown
November 11, 2025 at 1:20 AM
PSA for people with NIH grant periods starting January 1st (including most NIGMS MIRAs): your RPPR is due Saturday, but they haven’t sent out the usual automated reminders, presumably due to the shutdown
Reposted by Luca Caputo
Online now! ModulatingJAK2-STAT3 pathway promotes expansion & maturation of human iPSC-derived myogenic progenitor cells; advancing in vitro generation of skeletal muscle progenitor cells for potential cell therapy applications. https://ow.ly/6qAz50XkBvY
Sanford Burnham Prebys | ISSCR
Sanford Burnham Prebys | ISSCR
November 7, 2025 at 4:55 PM
Online now! ModulatingJAK2-STAT3 pathway promotes expansion & maturation of human iPSC-derived myogenic progenitor cells; advancing in vitro generation of skeletal muscle progenitor cells for potential cell therapy applications. https://ow.ly/6qAz50XkBvY
Sanford Burnham Prebys | ISSCR
Sanford Burnham Prebys | ISSCR
Reposted by Luca Caputo
Scaling back DEI isn’t just a moral setback—it’s a loss of innovation.
Bhalla, Trejo & @marymunson4.bsky.social in Nature Cell Biology: limiting who can participate in science “weakens research capacity and stifles discovery.”
doi.org/10.1038/s415...
Bhalla, Trejo & @marymunson4.bsky.social in Nature Cell Biology: limiting who can participate in science “weakens research capacity and stifles discovery.”
doi.org/10.1038/s415...
November 3, 2025 at 2:05 PM
Scaling back DEI isn’t just a moral setback—it’s a loss of innovation.
Bhalla, Trejo & @marymunson4.bsky.social in Nature Cell Biology: limiting who can participate in science “weakens research capacity and stifles discovery.”
doi.org/10.1038/s415...
Bhalla, Trejo & @marymunson4.bsky.social in Nature Cell Biology: limiting who can participate in science “weakens research capacity and stifles discovery.”
doi.org/10.1038/s415...
Reposted by Luca Caputo
RESEARCH PAPER: MYOD represses gene expression from non-E-box motifs
By Nicoletti, Massenet et al., Luca Caputo and Pier Lorenzo Puri
➡️ https://genesdev.cshlp.org/content/39/21-22/1299.abstract
#transcription #trancriptionfactor #epigenetics #muscle #stemcells
By Nicoletti, Massenet et al., Luca Caputo and Pier Lorenzo Puri
➡️ https://genesdev.cshlp.org/content/39/21-22/1299.abstract
#transcription #trancriptionfactor #epigenetics #muscle #stemcells
November 5, 2025 at 4:01 PM
RESEARCH PAPER: MYOD represses gene expression from non-E-box motifs
By Nicoletti, Massenet et al., Luca Caputo and Pier Lorenzo Puri
➡️ https://genesdev.cshlp.org/content/39/21-22/1299.abstract
#transcription #trancriptionfactor #epigenetics #muscle #stemcells
By Nicoletti, Massenet et al., Luca Caputo and Pier Lorenzo Puri
➡️ https://genesdev.cshlp.org/content/39/21-22/1299.abstract
#transcription #trancriptionfactor #epigenetics #muscle #stemcells
Reposted by Luca Caputo
All the people “afraid” of Zohran Mamdani are racist as hell.
November 5, 2025 at 12:13 AM
All the people “afraid” of Zohran Mamdani are racist as hell.
Reposted by Luca Caputo
Reposted by Luca Caputo
🚨 NEW ISSUE ALERT!!! 🚨
New Outlook, Review and Research articles online now at Genes & Development.
Click on the link to learn more:
➡️ https://genesdev.cshlp.org/content/39/21-22.toc
New Outlook, Review and Research articles online now at Genes & Development.
Click on the link to learn more:
➡️ https://genesdev.cshlp.org/content/39/21-22.toc
November 3, 2025 at 5:41 PM
🚨 NEW ISSUE ALERT!!! 🚨
New Outlook, Review and Research articles online now at Genes & Development.
Click on the link to learn more:
➡️ https://genesdev.cshlp.org/content/39/21-22.toc
New Outlook, Review and Research articles online now at Genes & Development.
Click on the link to learn more:
➡️ https://genesdev.cshlp.org/content/39/21-22.toc
📣 The paper is out!!
In this paper we tackled 2 major bottlenecks of cell therapy, namely how to increase the yield of progenitors in vitro and, by serendipity, how to mature them to an higher developmental stage.
#muscle #stemcelltherapy #muscleregeneration
www.cell.com/stem-cell-re...
In this paper we tackled 2 major bottlenecks of cell therapy, namely how to increase the yield of progenitors in vitro and, by serendipity, how to mature them to an higher developmental stage.
#muscle #stemcelltherapy #muscleregeneration
www.cell.com/stem-cell-re...
October 31, 2025 at 12:37 AM
📣 The paper is out!!
In this paper we tackled 2 major bottlenecks of cell therapy, namely how to increase the yield of progenitors in vitro and, by serendipity, how to mature them to an higher developmental stage.
#muscle #stemcelltherapy #muscleregeneration
www.cell.com/stem-cell-re...
In this paper we tackled 2 major bottlenecks of cell therapy, namely how to increase the yield of progenitors in vitro and, by serendipity, how to mature them to an higher developmental stage.
#muscle #stemcelltherapy #muscleregeneration
www.cell.com/stem-cell-re...
Adda passà a nuttata
October 30, 2025 at 2:18 AM
Adda passà a nuttata
If you introduce a trainee saying "I asked chatGPT..." I agree with the eel.
And ask the pronunciation of their surname, that is basic etiquette for fuck sake.
And ask the pronunciation of their surname, that is basic etiquette for fuck sake.
October 23, 2025 at 6:39 AM
If you introduce a trainee saying "I asked chatGPT..." I agree with the eel.
And ask the pronunciation of their surname, that is basic etiquette for fuck sake.
And ask the pronunciation of their surname, that is basic etiquette for fuck sake.
Galley proofs! 🥳💪🔬🧫
October 17, 2025 at 2:05 AM
Galley proofs! 🥳💪🔬🧫
Reposted by Luca Caputo
The ISSCR joins the global scientific community in mourning the loss of Nobel Laureate Sir John Gurdon whose enduring influence is woven into the very fabric of stem cell science.
https://ow.ly/BjHT50X8T6q
https://ow.ly/BjHT50X8T6q
ISSCR Remembers Sir John Gurdon — International Society for Stem Cell Research
The International Society for Stem Cell Research (ISSCR) joins the global scientific community in mourning the loss of Nobel Laureate Professor Sir John Gurdon, whose visionary discoveries forever changed our understanding of biology and inspired generations of scientists around the world. Professo
ow.ly
October 9, 2025 at 1:05 PM
The ISSCR joins the global scientific community in mourning the loss of Nobel Laureate Sir John Gurdon whose enduring influence is woven into the very fabric of stem cell science.
https://ow.ly/BjHT50X8T6q
https://ow.ly/BjHT50X8T6q
The email you wish to get before heading out to a conference "I am pleased to say that the reviewers have commented enthusiastically on your revised manuscript"
Stay tuned 🥳😉
Stay tuned 🥳😉
October 3, 2025 at 8:42 PM
The email you wish to get before heading out to a conference "I am pleased to say that the reviewers have commented enthusiastically on your revised manuscript"
Stay tuned 🥳😉
Stay tuned 🥳😉
Reposted by Luca Caputo
Vaccination: Risks and Benefits
Driving is important for our jobs and lifestyles, and the risk is quite low. So is vaccination.
www.nejm.org/doi/full/10....
Driving is important for our jobs and lifestyles, and the risk is quite low. So is vaccination.
www.nejm.org/doi/full/10....
September 26, 2025 at 2:54 PM
Vaccination: Risks and Benefits
Driving is important for our jobs and lifestyles, and the risk is quite low. So is vaccination.
www.nejm.org/doi/full/10....
Driving is important for our jobs and lifestyles, and the risk is quite low. So is vaccination.
www.nejm.org/doi/full/10....
Reposted by Luca Caputo
My quote of the day
The sole and basic source of our strength is the solidarity of workers, peasants and the intelligentsia, the solidarity of the nation, the solidarity of people who seek to live in dignity, truth, and in harmony with their conscience.
Lech Walesa
The sole and basic source of our strength is the solidarity of workers, peasants and the intelligentsia, the solidarity of the nation, the solidarity of people who seek to live in dignity, truth, and in harmony with their conscience.
Lech Walesa
September 16, 2025 at 10:55 AM
My quote of the day
The sole and basic source of our strength is the solidarity of workers, peasants and the intelligentsia, the solidarity of the nation, the solidarity of people who seek to live in dignity, truth, and in harmony with their conscience.
Lech Walesa
The sole and basic source of our strength is the solidarity of workers, peasants and the intelligentsia, the solidarity of the nation, the solidarity of people who seek to live in dignity, truth, and in harmony with their conscience.
Lech Walesa
According to a grant reviewer I have no proven experience on iPSCs 🤷
September 8, 2025 at 9:04 PM
According to a grant reviewer I have no proven experience on iPSCs 🤷
Resubmission button clicked.
Now some time off. See you all in ~10 days
Now some time off. See you all in ~10 days
August 21, 2025 at 11:22 PM
Resubmission button clicked.
Now some time off. See you all in ~10 days
Now some time off. See you all in ~10 days
Reposted by Luca Caputo
Really excited that our manuscript on Synovial Sarcoma is now online. Link to Open Access PDF: tinyurl.com/55bnssws
A summary🧵 :
A summary🧵 :
August 18, 2025 at 9:18 AM
Really excited that our manuscript on Synovial Sarcoma is now online. Link to Open Access PDF: tinyurl.com/55bnssws
A summary🧵 :
A summary🧵 :
Reposted by Luca Caputo
For decades, scientists thought MYOD was just a muscle-builder. But new research from Sanford Burnham Prebys shows this gene has a Jekyll-and-Hyde side—able to switch from activating muscle genes to silencing them.
sbpdiscovery.org/press/muscle...
sbpdiscovery.org/press/muscle...
August 14, 2025 at 4:28 AM
For decades, scientists thought MYOD was just a muscle-builder. But new research from Sanford Burnham Prebys shows this gene has a Jekyll-and-Hyde side—able to switch from activating muscle genes to silencing them.
sbpdiscovery.org/press/muscle...
sbpdiscovery.org/press/muscle...
We identified a novel role of MYOD as repressor of gene expression during somatic cell trans-differentiation by interaction at non-E-box motifs and a novel role of H4acme as a dynamic enhancer marker.
#MyoBlue #Epigenetics #Transcription #GeneRegulation
genesdev.cshlp.org/content/earl...
#MyoBlue #Epigenetics #Transcription #GeneRegulation
genesdev.cshlp.org/content/earl...
MYOD represses gene expression from non-E-box motifs
A biweekly scientific journal publishing high-quality research in molecular biology and genetics, cancer biology, biochemistry, and related fields
genesdev.cshlp.org
August 8, 2025 at 8:16 PM
We identified a novel role of MYOD as repressor of gene expression during somatic cell trans-differentiation by interaction at non-E-box motifs and a novel role of H4acme as a dynamic enhancer marker.
#MyoBlue #Epigenetics #Transcription #GeneRegulation
genesdev.cshlp.org/content/earl...
#MyoBlue #Epigenetics #Transcription #GeneRegulation
genesdev.cshlp.org/content/earl...
San Diego Pride 2025 is in the books.
We run, we march, we serve, but we don't hide
Happy Pride
We run, we march, we serve, but we don't hide
Happy Pride
July 21, 2025 at 9:35 PM
San Diego Pride 2025 is in the books.
We run, we march, we serve, but we don't hide
Happy Pride
We run, we march, we serve, but we don't hide
Happy Pride
The Pride Flag ceremony held at @sbpdiscovery.bsky.social at the beginning of the month goes in the right direction. 🏳️⚧️🏳️🌈
Protect transgender scientists | Science www.science.org/doi/10.1126/...
Protect transgender scientists | Science www.science.org/doi/10.1126/...
Protect transgender scientists
Transgender and gender nonconforming (TGnC) people are a primary target of the Trump administration. Multiple executive orders seek to erase TGnC protections; mandate denial of gender identity; and ba...
www.science.org
June 19, 2025 at 8:07 PM
The Pride Flag ceremony held at @sbpdiscovery.bsky.social at the beginning of the month goes in the right direction. 🏳️⚧️🏳️🌈
Protect transgender scientists | Science www.science.org/doi/10.1126/...
Protect transgender scientists | Science www.science.org/doi/10.1126/...
Reposted by Luca Caputo
Towards more sustainable research: reducing the environmental impact when working with #Drosophila. Challiner, Saurya., Patel, Raff, Fostier, Prokop, A. (2025) @genetics-gsa.bsky.social, in press -- doi.org/10.1093/gene... - Always happy to discuss and hear your ideas and views!
June 13, 2025 at 6:01 AM
Towards more sustainable research: reducing the environmental impact when working with #Drosophila. Challiner, Saurya., Patel, Raff, Fostier, Prokop, A. (2025) @genetics-gsa.bsky.social, in press -- doi.org/10.1093/gene... - Always happy to discuss and hear your ideas and views!
Reposted by Luca Caputo
📢 Protest Advice - Tear Gas 🪧
If you are protesting tomorrow - this video has great advice for preparing for and responding to tear gas. No makeup, contacts, etc.
If you live near a protest site - consider placing buckets of clean water outside your home so protestors have easy access. 🪣
If you are protesting tomorrow - this video has great advice for preparing for and responding to tear gas. No makeup, contacts, etc.
If you live near a protest site - consider placing buckets of clean water outside your home so protestors have easy access. 🪣
June 13, 2025 at 6:04 PM
📢 Protest Advice - Tear Gas 🪧
If you are protesting tomorrow - this video has great advice for preparing for and responding to tear gas. No makeup, contacts, etc.
If you live near a protest site - consider placing buckets of clean water outside your home so protestors have easy access. 🪣
If you are protesting tomorrow - this video has great advice for preparing for and responding to tear gas. No makeup, contacts, etc.
If you live near a protest site - consider placing buckets of clean water outside your home so protestors have easy access. 🪣