Tomas Rohal
@calvapo.bsky.social
People, kidneys, people's kidneys
Reposted by Tomas Rohal
Cool development
@nejm.org Evidence will publish a section in association with @cidrap.bsky.social on public health and vaccine issues usually covered by the now-dead MMWR
www.statnews.com/2025/10/21/c...
#publicHealth #MedSky
@nejm.org Evidence will publish a section in association with @cidrap.bsky.social on public health and vaccine issues usually covered by the now-dead MMWR
www.statnews.com/2025/10/21/c...
#publicHealth #MedSky
NEJM and public health group are launching rival to CDC’s MMWR publication
Two institutions are coming together to create an alternative to the CDC’s vaunted Morbidity and Mortality Weekly Report
www.statnews.com
October 26, 2025 at 4:15 AM
Cool development
@nejm.org Evidence will publish a section in association with @cidrap.bsky.social on public health and vaccine issues usually covered by the now-dead MMWR
www.statnews.com/2025/10/21/c...
#publicHealth #MedSky
@nejm.org Evidence will publish a section in association with @cidrap.bsky.social on public health and vaccine issues usually covered by the now-dead MMWR
www.statnews.com/2025/10/21/c...
#publicHealth #MedSky
Reposted by Tomas Rohal
Current European Alport guidelines suggest SGLT2i for CKD2 + proteinuria. I personally use if proteinuria not controlled with ACE/ARB no matter GFR. pubmed.ncbi.nlm.nih.gov/39673454/
October 25, 2025 at 8:49 PM
Current European Alport guidelines suggest SGLT2i for CKD2 + proteinuria. I personally use if proteinuria not controlled with ACE/ARB no matter GFR. pubmed.ncbi.nlm.nih.gov/39673454/
Reposted by Tomas Rohal
Data from executed Chinese prisoners and organs transplanted remain published
retractionwatch.com/2025/10/24/d...
#TransplantEthics
retractionwatch.com/2025/10/24/d...
#TransplantEthics
Despite new retractions, suspect organ transplant papers remain in the literature
Six years after researchers called for the retraction of more than 400 papers about organ transplantation amid suspicion the organs used in the studies came from executed Chinese prisoners, journal…
retractionwatch.com
October 24, 2025 at 9:01 PM
Data from executed Chinese prisoners and organs transplanted remain published
retractionwatch.com/2025/10/24/d...
#TransplantEthics
retractionwatch.com/2025/10/24/d...
#TransplantEthics
In patients with antiHBc total positivity with negative DNA, do you use rituximab (eg AAV) with HBV prophylaxis as a safe alternative? Thank you #askrenal
September 27, 2025 at 6:24 AM
In patients with antiHBc total positivity with negative DNA, do you use rituximab (eg AAV) with HBV prophylaxis as a safe alternative? Thank you #askrenal
Reposted by Tomas Rohal
And it’s live
Iptacopan in C3GN makes it to @thelancet.com
www.thelancet.com/journals/lan...
#NephSky
Iptacopan in C3GN makes it to @thelancet.com
www.thelancet.com/journals/lan...
#NephSky
September 26, 2025 at 9:37 AM
And it’s live
Iptacopan in C3GN makes it to @thelancet.com
www.thelancet.com/journals/lan...
#NephSky
Iptacopan in C3GN makes it to @thelancet.com
www.thelancet.com/journals/lan...
#NephSky
Have you ever converted a patient after kidney transplantation from tacrolimus to belatacept to improve progressing neuropathy? Have you noticed any beneficial effect? Thank you! #askrenal
June 12, 2025 at 8:32 AM
Have you ever converted a patient after kidney transplantation from tacrolimus to belatacept to improve progressing neuropathy? Have you noticed any beneficial effect? Thank you! #askrenal
Reposted by Tomas Rohal
Correct. Clinical engineering departments at hospitals/health systems can, theoretically, calibrate devices for you. They typically do this either with a mercury tower or with another device that was recently calibrated. We keep a mercury tower on hand to do this for our research studies 1/2
May 9, 2025 at 3:14 PM
Correct. Clinical engineering departments at hospitals/health systems can, theoretically, calibrate devices for you. They typically do this either with a mercury tower or with another device that was recently calibrated. We keep a mercury tower on hand to do this for our research studies 1/2
Reposted by Tomas Rohal
The ASIs have arrived
www.nejm.org/doi/full/10....
Aldosterone synthase inhibitors - first one to finish the phase 3 line
#Lorundrostat #Hypertension
www.nejm.org/doi/full/10....
Aldosterone synthase inhibitors - first one to finish the phase 3 line
#Lorundrostat #Hypertension
Lorundrostat Efficacy and Safety in Patients with Uncontrolled Hypertension | NEJM
Aldosterone dysregulation contributes to hypertension. Lorundrostat is an aldosterone synthase inhibitor, but data on its efficacy and safety in patients with hypertension are limited. In this mult...
www.nejm.org
April 23, 2025 at 10:01 PM
The ASIs have arrived
www.nejm.org/doi/full/10....
Aldosterone synthase inhibitors - first one to finish the phase 3 line
#Lorundrostat #Hypertension
www.nejm.org/doi/full/10....
Aldosterone synthase inhibitors - first one to finish the phase 3 line
#Lorundrostat #Hypertension
Reposted by Tomas Rohal
Moving to methods: the section you skip to get to the results #nephjc
Subheader: Like metformin in Stage 4 CKD, this won’t clear quickly...but we added jokes!
Subheader: Like metformin in Stage 4 CKD, this won’t clear quickly...but we added jokes!
April 16, 2025 at 1:20 AM
Moving to methods: the section you skip to get to the results #nephjc
Subheader: Like metformin in Stage 4 CKD, this won’t clear quickly...but we added jokes!
Subheader: Like metformin in Stage 4 CKD, this won’t clear quickly...but we added jokes!
Reposted by Tomas Rohal
just learned this & mind blown 🤯
CKD-EPI, MDRD etc give us GFR corrected for body surface area (ml/min/1.73m2)
BUT we're supposed to use the *absolute* GFR (ml/min) for drug dosing (eg KDIGO 2024 guidelines below; FDA agrees)
in obesity, the computer's ml/min/1.73m2 can be way too low #EMIMCC
CKD-EPI, MDRD etc give us GFR corrected for body surface area (ml/min/1.73m2)
BUT we're supposed to use the *absolute* GFR (ml/min) for drug dosing (eg KDIGO 2024 guidelines below; FDA agrees)
in obesity, the computer's ml/min/1.73m2 can be way too low #EMIMCC
April 14, 2025 at 3:01 PM
just learned this & mind blown 🤯
CKD-EPI, MDRD etc give us GFR corrected for body surface area (ml/min/1.73m2)
BUT we're supposed to use the *absolute* GFR (ml/min) for drug dosing (eg KDIGO 2024 guidelines below; FDA agrees)
in obesity, the computer's ml/min/1.73m2 can be way too low #EMIMCC
CKD-EPI, MDRD etc give us GFR corrected for body surface area (ml/min/1.73m2)
BUT we're supposed to use the *absolute* GFR (ml/min) for drug dosing (eg KDIGO 2024 guidelines below; FDA agrees)
in obesity, the computer's ml/min/1.73m2 can be way too low #EMIMCC
Reposted by Tomas Rohal
Final_Version_of_Tarrifs_actualFINALcopy_version7_USETHISONE.docx
April 9, 2025 at 6:39 PM
Final_Version_of_Tarrifs_actualFINALcopy_version7_USETHISONE.docx
Reposted by Tomas Rohal
April 7, 2025 at 1:02 PM
Reposted by Tomas Rohal
#WeekendRead from #EditorsChoice archives
Correlates of Nocturnal Hypertension
academic.oup.com/ajh/article/...
#OpenAccess and #Free
Correlates of Nocturnal Hypertension
academic.oup.com/ajh/article/...
#OpenAccess and #Free
April 6, 2025 at 10:49 AM
#WeekendRead from #EditorsChoice archives
Correlates of Nocturnal Hypertension
academic.oup.com/ajh/article/...
#OpenAccess and #Free
Correlates of Nocturnal Hypertension
academic.oup.com/ajh/article/...
#OpenAccess and #Free
Reposted by Tomas Rohal
Hydroxychloroquine for all patients with lupus nephritis? Yes 🆚 No
Spoiler: 🤝 😎 #NephroContinue
🔗 Yes: academic.oup.com/ndt/article/...
🔗 No: academic.oup.com/ndt/article/...
Spoiler: 🤝 😎 #NephroContinue
🔗 Yes: academic.oup.com/ndt/article/...
🔗 No: academic.oup.com/ndt/article/...
April 5, 2025 at 8:30 PM
Hydroxychloroquine for all patients with lupus nephritis? Yes 🆚 No
Spoiler: 🤝 😎 #NephroContinue
🔗 Yes: academic.oup.com/ndt/article/...
🔗 No: academic.oup.com/ndt/article/...
Spoiler: 🤝 😎 #NephroContinue
🔗 Yes: academic.oup.com/ndt/article/...
🔗 No: academic.oup.com/ndt/article/...
Reposted by Tomas Rohal
Global health equity: I nominate @thecurbsiders.bsky.social for creating an entire internal medicine curriculum that can be accessed for free around the world. Incredible reach and impact
Call for Nominations:
The 2025 Paul Farmer Lectureship and Award for Global Health Equity
www.mcgill.ca/spgh/about-u...
The 2025 Paul Farmer Lectureship and Award for Global Health Equity
www.mcgill.ca/spgh/about-u...
April 5, 2025 at 11:30 AM
Global health equity: I nominate @thecurbsiders.bsky.social for creating an entire internal medicine curriculum that can be accessed for free around the world. Incredible reach and impact
Reposted by Tomas Rohal
Reposted by Tomas Rohal
Katrina occurred in my first year in private practice. I have to say living through a disaster is scary as a doc, but utterly horrific as a patient. We also had a dialysis unit destroyed by 🌪️
When I see fires, floods & hurricanes I immediately think “what about the dialysis patients?” #NephMadness
When I see fires, floods & hurricanes I immediately think “what about the dialysis patients?” #NephMadness
a picture of a cartoon character with the words " disaster 's in the air " on the bottom
ALT: a picture of a cartoon character with the words " disaster 's in the air " on the bottom
media.tenor.com
March 2, 2025 at 2:19 PM
Katrina occurred in my first year in private practice. I have to say living through a disaster is scary as a doc, but utterly horrific as a patient. We also had a dialysis unit destroyed by 🌪️
When I see fires, floods & hurricanes I immediately think “what about the dialysis patients?” #NephMadness
When I see fires, floods & hurricanes I immediately think “what about the dialysis patients?” #NephMadness
Reposted by Tomas Rohal
⚡️New drugs, new electrolyte twists⚡️
ICIs, SGLT2i, ARNI, ns-MRA,GLP-1RA—game changers in nephrology, but are we watching their electrolyte impact closely?
This table breaks it down!
👀 Surprised
📖 doi.org/10.1007/s101...
#Nephrology #OncoNephrology #MedSky #Electrolytes
ICIs, SGLT2i, ARNI, ns-MRA,GLP-1RA—game changers in nephrology, but are we watching their electrolyte impact closely?
This table breaks it down!
👀 Surprised
📖 doi.org/10.1007/s101...
#Nephrology #OncoNephrology #MedSky #Electrolytes
March 1, 2025 at 2:38 AM
⚡️New drugs, new electrolyte twists⚡️
ICIs, SGLT2i, ARNI, ns-MRA,GLP-1RA—game changers in nephrology, but are we watching their electrolyte impact closely?
This table breaks it down!
👀 Surprised
📖 doi.org/10.1007/s101...
#Nephrology #OncoNephrology #MedSky #Electrolytes
ICIs, SGLT2i, ARNI, ns-MRA,GLP-1RA—game changers in nephrology, but are we watching their electrolyte impact closely?
This table breaks it down!
👀 Surprised
📖 doi.org/10.1007/s101...
#Nephrology #OncoNephrology #MedSky #Electrolytes
Reposted by Tomas Rohal
Interesting: 162 mg = 81 mg in preeclampsia prevention but with more adverse events
Abstract from SFM conference reported here www.medpagetoday.com/meetingcover...
ASAPP trial, N = 400 clinicaltrials.gov/study/NCT040...
Abstract from SFM conference reported here www.medpagetoday.com/meetingcover...
ASAPP trial, N = 400 clinicaltrials.gov/study/NCT040...
No Added Benefit With Higher Aspirin Dose for Patients at High Risk of Preeclampsia
However, higher dose may benefit multifetal pregnancies
www.medpagetoday.com
February 15, 2025 at 6:41 PM
Interesting: 162 mg = 81 mg in preeclampsia prevention but with more adverse events
Abstract from SFM conference reported here www.medpagetoday.com/meetingcover...
ASAPP trial, N = 400 clinicaltrials.gov/study/NCT040...
Abstract from SFM conference reported here www.medpagetoday.com/meetingcover...
ASAPP trial, N = 400 clinicaltrials.gov/study/NCT040...
Reposted by Tomas Rohal
February 7, 2025 at 5:00 AM
Reposted by Tomas Rohal
Eisei Sohara talking about importance of genetic testing in CKD.
➡️10-15% of so called ADPKD do not have family history yet have PKD1/2 mutation.
➡️ Other genes involved in PKD (IFT40, CFAP47).
➡️10% of dialysis patients with unknown cause actually have genetic cause.
#ISNWCN
➡️10-15% of so called ADPKD do not have family history yet have PKD1/2 mutation.
➡️ Other genes involved in PKD (IFT40, CFAP47).
➡️10% of dialysis patients with unknown cause actually have genetic cause.
#ISNWCN
February 7, 2025 at 5:25 AM
Eisei Sohara talking about importance of genetic testing in CKD.
➡️10-15% of so called ADPKD do not have family history yet have PKD1/2 mutation.
➡️ Other genes involved in PKD (IFT40, CFAP47).
➡️10% of dialysis patients with unknown cause actually have genetic cause.
#ISNWCN
➡️10-15% of so called ADPKD do not have family history yet have PKD1/2 mutation.
➡️ Other genes involved in PKD (IFT40, CFAP47).
➡️10% of dialysis patients with unknown cause actually have genetic cause.
#ISNWCN