@bhadurilab.bsky.social
🧵Excited to share our new preprint introducing iHOTT - an autologous tumor-immune co-culture model that captures patient-specific responses in #Glioblastoma
💥Now on
@biorxivpreprint
: biorxiv.org/content/10.1...
Led by Dr. Shivani Baisiwala, Neurosurgery Resident in the lab
💥Now on
@biorxivpreprint
: biorxiv.org/content/10.1...
Led by Dr. Shivani Baisiwala, Neurosurgery Resident in the lab
biorxiv.org
June 24, 2025 at 2:24 AM
🧵Excited to share our new preprint introducing iHOTT - an autologous tumor-immune co-culture model that captures patient-specific responses in #Glioblastoma
💥Now on
@biorxivpreprint
: biorxiv.org/content/10.1...
Led by Dr. Shivani Baisiwala, Neurosurgery Resident in the lab
💥Now on
@biorxivpreprint
: biorxiv.org/content/10.1...
Led by Dr. Shivani Baisiwala, Neurosurgery Resident in the lab
Excited to present our new preprint led by @claudianguyen95 uncovering how thalamic input shapes human cortical development! We discover that thalamic axons promote the generation of upper layer cortical neurons through NRXN1-mediated contacts with outer radial glia. www.biorxiv.org/content/10.1...
May 6, 2025 at 4:50 PM
Excited to present our new preprint led by @claudianguyen95 uncovering how thalamic input shapes human cortical development! We discover that thalamic axons promote the generation of upper layer cortical neurons through NRXN1-mediated contacts with outer radial glia. www.biorxiv.org/content/10.1...
Congratulations @prnano9.bsky.social!!! We are thrilled that this paper is out and hope everyone enjoys using the datasets and meta-atlas tools!!
It’s out! The first paper from my postdoc – and first from the @bhadurilab.bsky.social – is now live @natneuro.nature.com . 🧠✨
Using a new meta-atlas generation strategy, we identified functional gene networks that more fully explain how cell types are formed in the human cortex. (1/13)
Using a new meta-atlas generation strategy, we identified functional gene networks that more fully explain how cell types are formed in the human cortex. (1/13)
Parallel meta-analyses of the human cortex in development (seven datasets) and adulthood (16 datasets) generated over 500 gene co-expression networks that can describe mechanisms of cortical development, centering on peak stages of neurogenesis 🧠🧪
www.nature.com/articles/s41...
www.nature.com/articles/s41...
May 2, 2025 at 1:03 AM
Congratulations @prnano9.bsky.social!!! We are thrilled that this paper is out and hope everyone enjoys using the datasets and meta-atlas tools!!
Delighted to share our most recent preprint led by the incredible @MilJessenya and @Jalbsoto! In this study, we generated a metabolomic atlas of human cortical development and discovered that the pentose phosphate pathway regulates radial glia cell fate. www.biorxiv.org/content/10.1...
Metabolic Atlas of Early Human Cortex Identifies Regulators of Cell Fate Transitions
Characterization of cell type emergence during human cortical development, which enables unique human cognition, has focused primarily on anatomical and transcriptional characterizations. Metabolic pr...
www.biorxiv.org
March 13, 2025 at 4:36 AM
Delighted to share our most recent preprint led by the incredible @MilJessenya and @Jalbsoto! In this study, we generated a metabolomic atlas of human cortical development and discovered that the pentose phosphate pathway regulates radial glia cell fate. www.biorxiv.org/content/10.1...
Reposted
It’s good to be in California these days. Come join us! We’ve got an open post-doc position funded by CA institute for regenerative medicine. It’s a big multi-disciplinary team science project led by @bhadurilab.bsky.social. Organoid transplants, neuro development, 2P! bri.ucla.edu/open-positio...
Postdoctoral Scholar – Laboratory of Dr. William Zeiger – UCLA Brain Research Institute (BRI)
bri.ucla.edu
February 5, 2025 at 12:37 AM
It’s good to be in California these days. Come join us! We’ve got an open post-doc position funded by CA institute for regenerative medicine. It’s a big multi-disciplinary team science project led by @bhadurilab.bsky.social. Organoid transplants, neuro development, 2P! bri.ucla.edu/open-positio...
Thank you to the @uclastemcell.bsky.social for their unwavering support and for this piece on our lab!
Member Spotlight: Meet Dr. Aparna Bhaduri, a neuroscientist whose work bridges human brain development and cancer research. Here, she shares how she uses “mini brain” organoids in her lab, what drives her curiosity and her passion for rock climbing.
ucla.in/3CMa9g4
ucla.in/3CMa9g4
Member Spotlight: Aparna Bhaduri studies brain development to identify cancer origins
Meet Dr. Aparna Bhaduri, a neuroscientist whose work bridges human brain development and cancer research. She investigates how the many different cell types in the brain arise and explores why certain...
ucla.in
February 5, 2025 at 8:13 PM
Thank you to the @uclastemcell.bsky.social for their unwavering support and for this piece on our lab!