Patricia Nano
@prnano9.bsky.social
Postdoc @bhadurilab.bsky.social
Human brain development + single-cell omics
Human brain development + single-cell omics
Pinned
Patricia Nano
@prnano9.bsky.social
· May 2
Parallel meta-analyses of the human cortex in development (seven datasets) and adulthood (16 datasets) generated over 500 gene co-expression networks that can describe mechanisms of cortical development, centering on peak stages of neurogenesis 🧠🧪
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Integrated analysis of molecular atlases unveils modules driving developmental cell subtype specification in the human cortex - Nature Neuroscience
Nano et al. introduce a pipeline to generate meta-atlases of the human brain from existing single-cell datasets and extract gene modules linked to cell fate specification. Perturbing these programs in...
www.nature.com
It’s out! The first paper from my postdoc – and first from the @bhadurilab.bsky.social – is now live @natneuro.nature.com . 🧠✨
Using a new meta-atlas generation strategy, we identified functional gene networks that more fully explain how cell types are formed in the human cortex. (1/13)
Using a new meta-atlas generation strategy, we identified functional gene networks that more fully explain how cell types are formed in the human cortex. (1/13)
Reposted by Patricia Nano
🧵Excited to share our new preprint introducing iHOTT - an autologous tumor-immune co-culture model that captures patient-specific responses in #Glioblastoma
💥Now on
@biorxivpreprint
: biorxiv.org/content/10.1...
Led by Dr. Shivani Baisiwala, Neurosurgery Resident in the lab
💥Now on
@biorxivpreprint
: biorxiv.org/content/10.1...
Led by Dr. Shivani Baisiwala, Neurosurgery Resident in the lab
biorxiv.org
June 24, 2025 at 2:24 AM
🧵Excited to share our new preprint introducing iHOTT - an autologous tumor-immune co-culture model that captures patient-specific responses in #Glioblastoma
💥Now on
@biorxivpreprint
: biorxiv.org/content/10.1...
Led by Dr. Shivani Baisiwala, Neurosurgery Resident in the lab
💥Now on
@biorxivpreprint
: biorxiv.org/content/10.1...
Led by Dr. Shivani Baisiwala, Neurosurgery Resident in the lab
Honored to join this amazing community 🎉
We are thrilled to announce the 2025 Leading Edge Fellows! 40 outstanding postdoctoral fellows doing pioneering research in a wide range of biological and biomedical disciplines.
Learn more about these exceptional scientists:
www.leadingedgesymposium.org/fellows
Learn more about these exceptional scientists:
www.leadingedgesymposium.org/fellows
June 2, 2025 at 7:34 PM
Honored to join this amazing community 🎉
Reposted by Patricia Nano
Excited to present our new preprint led by @claudianguyen95 uncovering how thalamic input shapes human cortical development! We discover that thalamic axons promote the generation of upper layer cortical neurons through NRXN1-mediated contacts with outer radial glia. www.biorxiv.org/content/10.1...
May 6, 2025 at 4:50 PM
Excited to present our new preprint led by @claudianguyen95 uncovering how thalamic input shapes human cortical development! We discover that thalamic axons promote the generation of upper layer cortical neurons through NRXN1-mediated contacts with outer radial glia. www.biorxiv.org/content/10.1...
It’s out! The first paper from my postdoc – and first from the @bhadurilab.bsky.social – is now live @natneuro.nature.com . 🧠✨
Using a new meta-atlas generation strategy, we identified functional gene networks that more fully explain how cell types are formed in the human cortex. (1/13)
Using a new meta-atlas generation strategy, we identified functional gene networks that more fully explain how cell types are formed in the human cortex. (1/13)
Parallel meta-analyses of the human cortex in development (seven datasets) and adulthood (16 datasets) generated over 500 gene co-expression networks that can describe mechanisms of cortical development, centering on peak stages of neurogenesis 🧠🧪
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Integrated analysis of molecular atlases unveils modules driving developmental cell subtype specification in the human cortex - Nature Neuroscience
Nano et al. introduce a pipeline to generate meta-atlases of the human brain from existing single-cell datasets and extract gene modules linked to cell fate specification. Perturbing these programs in...
www.nature.com
May 2, 2025 at 12:39 AM
It’s out! The first paper from my postdoc – and first from the @bhadurilab.bsky.social – is now live @natneuro.nature.com . 🧠✨
Using a new meta-atlas generation strategy, we identified functional gene networks that more fully explain how cell types are formed in the human cortex. (1/13)
Using a new meta-atlas generation strategy, we identified functional gene networks that more fully explain how cell types are formed in the human cortex. (1/13)