Ada Jimenez-Gonzalez
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Ada Jimenez-Gonzalez
@adajg.bsky.social
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Ada Jimenez-Gonzalez @adajg.bsky.social · Dec 20
New preprint alert! 🚨 Check this fantastic paper on Turbot's embryogenesis from the Martinez's lab. Excellent work by @aramburico.bsky.social and all co-authors and framed in the AQUA-FAANG project. Very grateful to have contributed to it!
aramburico.bsky.social Óscar Aramburu, a.k.a. "Aramburico" @aramburico.bsky.social · Dec 18
Happy to share our preprint on the epigenomics of embryogenesis in turbot! Congrats and thanks to all the co-authors and the AQUA-FAANG project for all the hard work 🙂https://www.biorxiv.org/content/10.1101/2024.12.12.628162v1
Epigenomics of embryogenesis in turbot (Scophthalmus maximus)
Embryogenesis is the crucial first step of ontogeny, where an organism with a complex body plan arises from a single undifferentiated totipotent cell. This process is orchestrated by dynamic changes i...
www.biorxiv.org
Reposted by Ada Jimenez-Gonzalez
cp-cellreports.bsky.social
In vivo differentiation of embryonic cells devoid of key reprogramming factors
In vivo differentiation of embryonic cells devoid of key reprogramming factors
Youlten, Miao et al. use zebrafish transplantation to understand the fate of cells lacking pluripotency factors Nanog, Pou5f3, and Sox19b (NPS) in developmental reprogramming and cell identity establishment. They found that NPS are required for proper cell identity for most, but not all, lineages, likely through nuclear and cytoplasmic reprogramming.
dlvr.it
November 12, 2025 at 8:50 PM
Reposted by Ada Jimenez-Gonzalez
destinationeu.bsky.social
This whole thing is out of control.
The Ecological Cost of AI Is Much Higher Than You Think - Truthdig
As the demands of AI grow, each generation of microchips requires more energy, minerals and water to produce, driving a ruinous cycle.
www.truthdig.com
November 13, 2025 at 6:51 AM
Reposted by Ada Jimenez-Gonzalez
jamesbriscoe.bsky.social
Check out this month's handpicked preprints in developmantal & stem cell biology on the Node

thenode.biologists.com/prelighters-...
thenode.biologists.com
November 13, 2025 at 8:18 AM
Reposted by Ada Jimenez-Gonzalez
mads100tist.bsky.social
It's online! In this series of perspectives @dev-journal.bsky.social, yours truly talks about the exciting open questions and many things to do in the field of dev bio and neuroscience #DevBio🧪 #PIsOfTomorrow journals.biologists.com/dev/article/...
Pathway to Independence: a forecast for the future of developmental biology
ABSTRACT. In 2022, Development launched its Pathway to Independence (PI) programme, aimed at supporting postdocs as they transition to their first independent position. In 2025, we welcome our third c...
journals.biologists.com
September 30, 2025 at 11:00 AM
Reposted by Ada Jimenez-Gonzalez
olivia.science
Pretty sure real science is actually reading the papers, thinking very deeply, and more, before writing, not generating literature review-like objects with no authorial intent or legwork
iaincheeseman.bsky.social Iain Cheeseman @iaincheeseman.bsky.social · Oct 20
Today @anthropic.com released PubMed integration for Claude. No hallucinations. Just real science, real data. As a beta tester, this has been game changing— a supercharged research tool. Here are 6 prompts that will transform how you search the literature. A 🧵

www.anthropic.com/news/claude-...
Claude for Life Sciences
Discover how Claude accelerates life sciences research with new scientific connectors, skills, and improved performance for drug discovery and clinical work.
www.anthropic.com
October 20, 2025 at 6:53 PM
Reposted by Ada Jimenez-Gonzalez
kristalerista.bsky.social
Dear funding agencies,

I know we all want to discover the wonder drug that will cure the horrible diseases, but to do that, we need to invest in basic, unsexy, foundational research on how the systems work. Funding can’t all be drug development.

Sincerely,
Looking for basic research grants.
October 14, 2025 at 7:24 PM
Reposted by Ada Jimenez-Gonzalez
andrewtosolini.bsky.social
Do all #NTFs regulate #MotorNeuron axonal transport in vivo?

Our new preprint shows they do not.

#BDNF enhances (shorturl.at/siwFi), #CNTF slows, and #HGF, #NRTN & #proBDNF show no effect.

#AxonalTransport regulation is selective, not universal.

@jamessleigh.bsky.social @uclqsion.bsky.social
October 15, 2025 at 6:48 AM
Reposted by Ada Jimenez-Gonzalez
andre-rendeiro.com
New work from Iva Buljan @ivabuljan.bsky.social in our lab!
We mapped how human tissue architecture changes with age using ~25k histology slides from 983 donors.
This is the first body-wide atlas of human microanatomy.
📄 Preprint: www.biorxiv.org/content/10.1...
October 15, 2025 at 6:29 AM
Reposted by Ada Jimenez-Gonzalez
brenttoderian.bsky.social
“In Finland, the number of homeless people has fallen sharply. Those affected receive a small apartment & counselling with no preconditions. 4 out of 5 people affected make their way back into a stable life. And all this is CHEAPER than accepting homelessness.”

It costs a lot less to house people.
Finland ends homelessness and provides shelter for all in need - scoop.me
In Finland, the number of homeless people has fallen sharply. Why? The country applies the "Housing First" concept agains homelessness.
thebetter.news
September 21, 2025 at 6:24 AM
Reposted by Ada Jimenez-Gonzalez
scholpplab.bsky.social
A huge thank you to everyone who made #UKZF2025 possible 🙌🐟 From inspiring talks and posters to lively discussions and community spirit — your energy and contributions turned this meeting into a real success. 💙✨
September 19, 2025 at 1:26 PM
Reposted by Ada Jimenez-Gonzalez
drn-sheffield.bsky.social
Several DRN members (present and past) attended and presented work at the recent #UKZF2025 #zebrafish meeting in Exmouth and Exeter.

Many thanks to the organisers Steffen @scholpplab.bsky.social, Carol @yhcarolyang.bsky.social, Soojin, Greg and Nik for a great meeting!
September 19, 2025 at 1:30 PM
Reposted by Ada Jimenez-Gonzalez
pathogenomenick.bsky.social
Terrific new feature presented by @theo.io on @pathoplexus.org called SeqSets for generating DOIs for sequence subsets used in publications, that can then be tracked for impact via CrossRef that will allow data generators to track impact! #IMMEMXiV
September 19, 2025 at 11:10 AM
Reposted by Ada Jimenez-Gonzalez
mskohut.bsky.social
History doesn’t repeat.
It is REPLICATED.
Very intentionally.
September 19, 2025 at 2:54 PM
Reposted by Ada Jimenez-Gonzalez
chrmosimann.bsky.social
Great to contribute to this wonderful initiative by @biologists.bsky.social!
biologists.bsky.social The Company of Biologists @biologists.bsky.social · Sep 19
In our Forest of Biologists we fund the restoration and preservation of ancient woodland and dedicate these trees to our peer reviewers.

There are now over 10,000 trees for peer reviews!

Thank you to all our peer reviewers. Find out more:
forest.biologists.com

#PRW2025 @peerreviewweek.bsky.social
Lots of illustrated trees. A sample image taken from the Forest of Biologists website.
September 19, 2025 at 4:37 PM
Reposted by Ada Jimenez-Gonzalez
rebeccasear.bsky.social
Tl;dr = No.

www.science.org/content/blog...
Can ChatGPT help science writers?
www.science.org
September 19, 2025 at 2:50 PM
Reposted by Ada Jimenez-Gonzalez
aurhin.bsky.social
Are digits modified fins, or evolutionary innovations? Read how we tackled this old question from a new angle🧪
A story with @chasebolt.bsky.social, @homeobox.bsky.social and myself, coordinated by @denisduboule.bsky.social from @college-de-france.fr and published in @nature.com today!
#InHoxWeTrust
hoxd13a reporter in a zebrafish larva
September 17, 2025 at 5:26 PM
Reposted by Ada Jimenez-Gonzalez
wbickmor.bsky.social
Honoured to be in Birmingham to mark Bryan Turner’s retirement- a gentleman and giant of epigenetics.
September 11, 2025 at 4:34 PM
Reposted by Ada Jimenez-Gonzalez
datarescueproject.org
Say you can't sleep, baby, we know, that's that [threat to government data].

Fuel up on espresso (or your favorite caffeinated beverage of choice) and join the #DataRescueVolunteers
FAQ
Welcome to the Data Rescue Project! We are excited to have you join us. What is the Data Rescue Project? The Data Rescue Project is a coordinated effort among a group of data organizations, including…
www.datarescueproject.org
August 22, 2025 at 1:15 PM
Reposted by Ada Jimenez-Gonzalez
dev-journal.bsky.social
Cnot3 is required for male germ cell development and spermatogonial stem cell maintenance

Read this #OA Research Article by Qing Chen, Safia Malki, Guang Hu and the team.

journals.biologists.com/dev/article/...
Fig. 3. Cnot3 deletion impairs the maintenance of steady-state spermatogenesis. (A) Reclustering of the group of cells containing SSCs and progenitor cells from the combination of our data with published datasets from P3, P6, P8, P10 and P15 stages (Law et al., 2019; Grive et al., 2019; Ernst et al., 2019). (B) Reclustering of the group of cells containing SSCs and progenitor cells from published datasets from P3, P6 and P15 stages, respectively (Law et al., 2019; Grive et al., 2019; Ernst et al., 2019). (C) Highlights of cell cycle phases in reclustered group of cells containing SSCs and progenitor cells from the combination of our data with published datasets from P3, P6, P8, P10 and P15 stages (Law et al., 2019; Grive et al., 2019; Ernst et al., 2019). (D) Reclustering and quantification of the groups of cells containing SSCs and progenitor cells from P8 control and Cnot3-cKO cells. (E) Highlights of Cnot3, stem cell (Lhx1 and Gfra1) and progenitor cell (Ngn3 and Ddit4) markers in reclustered group of cells containing SSCs and progenitor cells from P8 control and Cnot3-cKO cells.
August 17, 2025 at 8:46 AM
Reposted by Ada Jimenez-Gonzalez
biorxivpreprint.bsky.social
Tight translation regulation of the canonical C9ORF72 through a multi-component system https://www.biorxiv.org/content/10.1101/2025.08.09.669471v1
August 10, 2025 at 4:17 AM
Reposted by Ada Jimenez-Gonzalez
pacbio.bsky.social
Landmark study using #PacBio #HiFiSequencing reveals human-specific genetic variation not detectable with short reads. Researchers uncover new insights into brain evolution and potential links to cognition and autism.

Read the full paper: bit.ly/3IxQtPR

#BrainResearch
Human-specific gene expansions contribute to brain evolution
A complete human genome and functional modeling in zebrafish pinpoint gene expansions that may underlie the evolutionary innovations of the human brain.
bit.ly
July 21, 2025 at 5:45 PM
Reposted by Ada Jimenez-Gonzalez
vmetzis.bsky.social
Interested in developmental epigenetics? So are we! Apply now to join us for your postdoc!

Multiple positions across multiple groups @mrc-lms.bsky.social

Projects spanning germline demethylation, gene regulation, genome architecture in development & disease 👇👇

lms.mrc.ac.uk/work/vacanci...
MRC Postdoctoral Research Scientists x 5 - MRC Laboratory of Medical Sciences
Applications are now open for up to five postdoctoral positions in the area of developmental epigenetics.
lms.mrc.ac.uk
July 14, 2025 at 5:15 PM
Reposted by Ada Jimenez-Gonzalez
rebeccarhelm.bsky.social
I just learned these this elephant-trunked-shaped cells, known as ciliate, put their sexy DNA into a special pocket (called a generative nucleus), and the rest of their DNA in a normal get-shit-done nucleus.

It has functional specialization nuclei.

Respectfully: holy shit 🧵🧪
July 11, 2025 at 6:30 PM
Reposted by Ada Jimenez-Gonzalez
repeatmasker.bsky.social
Multiple Software Updates - RepeatMasker 4.2.0, RepeatModeler 2.0.7, and the newly released RepeatAfterMe tool. See www.repeatmasker.org for details.
RepeatMasker Home Page
www.repeatmasker.org
July 1, 2025 at 10:31 PM
Reposted by Ada Jimenez-Gonzalez
doodlesbycharlie.bsky.social
i’m fine
A 4-panel doodled black and white comic. In the first panel, a triangle character is talking to a circle character who's wearing a face mask. The triangle smiles, points at the circle, and says "It's smart you still wear a mask". In the second panel, the background is all black and the text is white. There's a close up of the triangle's face, who looks worried with bags under their eyes. Text above them reads "When I had Covid, I couldn't taste food for nine months. It hurt to breathe. My lungs haven't been the same..." In the third panel, it's back to a white background and inked doodles. The circle holds up a mask to the triangle and says "I'm sorry. I have masks you can use?" The triangle looks at the circle with a neutral expression and open mouth. In the final panel, the triangle runs away with a happy expression and says "No, I'm fine!" The circle turns to face us with a blank expression, with the spare mask still in hand but lowered to the ground. Made by doodlesbycharlie_.
November 15, 2024 at 1:57 AM