Andrew Tosolini
@andrewtosolini.bsky.social
Senior researcher at The University of Queensland - Ngo and Steyn Labs. Schiavo Lab alumni. Interested in MND/ALS, motor neurons, NMJs, and of course axonal transport. Hobbies include the Socceroos, the Australian Cricket team and Chelsea FC.
Pinned
Do all #NTFs regulate #MotorNeuron axonal transport in vivo?
Our new preprint shows they do not.
#BDNF enhances (shorturl.at/siwFi), #CNTF slows, and #HGF, #NRTN & #proBDNF show no effect.
#AxonalTransport regulation is selective, not universal.
@jamessleigh.bsky.social @uclqsion.bsky.social
Our new preprint shows they do not.
#BDNF enhances (shorturl.at/siwFi), #CNTF slows, and #HGF, #NRTN & #proBDNF show no effect.
#AxonalTransport regulation is selective, not universal.
@jamessleigh.bsky.social @uclqsion.bsky.social
Do all #NTFs regulate #MotorNeuron axonal transport in vivo?
Our new preprint shows they do not.
#BDNF enhances (shorturl.at/siwFi), #CNTF slows, and #HGF, #NRTN & #proBDNF show no effect.
#AxonalTransport regulation is selective, not universal.
@jamessleigh.bsky.social @uclqsion.bsky.social
Our new preprint shows they do not.
#BDNF enhances (shorturl.at/siwFi), #CNTF slows, and #HGF, #NRTN & #proBDNF show no effect.
#AxonalTransport regulation is selective, not universal.
@jamessleigh.bsky.social @uclqsion.bsky.social
October 15, 2025 at 6:48 AM
Do all #NTFs regulate #MotorNeuron axonal transport in vivo?
Our new preprint shows they do not.
#BDNF enhances (shorturl.at/siwFi), #CNTF slows, and #HGF, #NRTN & #proBDNF show no effect.
#AxonalTransport regulation is selective, not universal.
@jamessleigh.bsky.social @uclqsion.bsky.social
Our new preprint shows they do not.
#BDNF enhances (shorturl.at/siwFi), #CNTF slows, and #HGF, #NRTN & #proBDNF show no effect.
#AxonalTransport regulation is selective, not universal.
@jamessleigh.bsky.social @uclqsion.bsky.social
A wonderful collaboration. Congratulations to @nicolbirsa.bsky.social & @beccasimkin.bsky.social and all the co-authors #axonaltransport #FUS #MND #ALS #NMJ
Very excited to share our latest preprint! We looked at loss and gain of function, innervation, reinnervation, and in vivo axonal transport in a FUS-ALS mouse model!
www.biorxiv.org/content/10.1...
@uclqsion.bsky.social @beccasimkin.bsky.social @andrewtosolini.bsky.social @frattalab.bsky.social
www.biorxiv.org/content/10.1...
@uclqsion.bsky.social @beccasimkin.bsky.social @andrewtosolini.bsky.social @frattalab.bsky.social
June 18, 2025 at 12:07 PM
A wonderful collaboration. Congratulations to @nicolbirsa.bsky.social & @beccasimkin.bsky.social and all the co-authors #axonaltransport #FUS #MND #ALS #NMJ
Reposted by Andrew Tosolini
Our new paper in Neurobiology of Aging showing that processivity and BDNF-dependent modulation of #AxonalTransport are impaired in aged mice:
www.sciencedirect.com/science/arti...
@dvillarroelc.bsky.social @andrewtosolini.bsky.social @alessiovagnoni.bsky.social @uclqsion.bsky.social #aging
www.sciencedirect.com/science/arti...
@dvillarroelc.bsky.social @andrewtosolini.bsky.social @alessiovagnoni.bsky.social @uclqsion.bsky.social #aging
May 30, 2025 at 12:34 PM
Our new paper in Neurobiology of Aging showing that processivity and BDNF-dependent modulation of #AxonalTransport are impaired in aged mice:
www.sciencedirect.com/science/arti...
@dvillarroelc.bsky.social @andrewtosolini.bsky.social @alessiovagnoni.bsky.social @uclqsion.bsky.social #aging
www.sciencedirect.com/science/arti...
@dvillarroelc.bsky.social @andrewtosolini.bsky.social @alessiovagnoni.bsky.social @uclqsion.bsky.social #aging
🚨New
@biorxivpreprint.bsky.social
collab b/w Fisher, Cunningham, Gilthorpe &
Schiavo Labs. @mrcharwell.bsky.social @uclqsion.bsky.social @umeauniversitet.bsky.social
Metabolic alterations in the absence of a detectable neuromuscular phenotype in novel humanised SOD1A4V mice.
t.co/u01CG6ctTS
@biorxivpreprint.bsky.social
collab b/w Fisher, Cunningham, Gilthorpe &
Schiavo Labs. @mrcharwell.bsky.social @uclqsion.bsky.social @umeauniversitet.bsky.social
Metabolic alterations in the absence of a detectable neuromuscular phenotype in novel humanised SOD1A4V mice.
t.co/u01CG6ctTS
https://www.biorxiv.org/content/10.1101/2025.05.01.650597v1
t.co
May 6, 2025 at 1:00 AM
🚨New
@biorxivpreprint.bsky.social
collab b/w Fisher, Cunningham, Gilthorpe &
Schiavo Labs. @mrcharwell.bsky.social @uclqsion.bsky.social @umeauniversitet.bsky.social
Metabolic alterations in the absence of a detectable neuromuscular phenotype in novel humanised SOD1A4V mice.
t.co/u01CG6ctTS
@biorxivpreprint.bsky.social
collab b/w Fisher, Cunningham, Gilthorpe &
Schiavo Labs. @mrcharwell.bsky.social @uclqsion.bsky.social @umeauniversitet.bsky.social
Metabolic alterations in the absence of a detectable neuromuscular phenotype in novel humanised SOD1A4V mice.
t.co/u01CG6ctTS
Reposted by Andrew Tosolini
In our latest pre-print, we show that processivity and BDNF-dependent modulation of #AxonalTransport are impaired in aged mice:
www.biorxiv.org/content/10.1...
Well done team! @dvillarroelc.bsky.social @andrewtosolini.bsky.social @alessiovagnoni.bsky.social et al.
@uclqsion.bsky.social #aging
www.biorxiv.org/content/10.1...
Well done team! @dvillarroelc.bsky.social @andrewtosolini.bsky.social @alessiovagnoni.bsky.social et al.
@uclqsion.bsky.social #aging
February 2, 2025 at 8:47 AM
In our latest pre-print, we show that processivity and BDNF-dependent modulation of #AxonalTransport are impaired in aged mice:
www.biorxiv.org/content/10.1...
Well done team! @dvillarroelc.bsky.social @andrewtosolini.bsky.social @alessiovagnoni.bsky.social et al.
@uclqsion.bsky.social #aging
www.biorxiv.org/content/10.1...
Well done team! @dvillarroelc.bsky.social @andrewtosolini.bsky.social @alessiovagnoni.bsky.social et al.
@uclqsion.bsky.social #aging
A little about me! 🦋 With help from Scholar Goggler scholargoggler.com
November 25, 2024 at 2:19 PM
A little about me! 🦋 With help from Scholar Goggler scholargoggler.com
Reposted by Andrew Tosolini
I will try to take on the challenge to highlight some of the cool bioimage analysis tools we use all the time. #BioimageTooloftheDay
I will start with ijp-LaRoMe, a very nifty Fiji plugin that I use all the time to convert ROI to label images and vice versa
github.com/BIOP/ijp-LaR...
I will start with ijp-LaRoMe, a very nifty Fiji plugin that I use all the time to convert ROI to label images and vice versa
github.com/BIOP/ijp-LaR...
GitHub - BIOP/ijp-LaRoMe: some useful function to get Label from ROIs and vice versa , and more!
some useful function to get Label from ROIs and vice versa , and more! - BIOP/ijp-LaRoMe
github.com
November 11, 2024 at 7:13 AM
I will try to take on the challenge to highlight some of the cool bioimage analysis tools we use all the time. #BioimageTooloftheDay
I will start with ijp-LaRoMe, a very nifty Fiji plugin that I use all the time to convert ROI to label images and vice versa
github.com/BIOP/ijp-LaR...
I will start with ijp-LaRoMe, a very nifty Fiji plugin that I use all the time to convert ROI to label images and vice versa
github.com/BIOP/ijp-LaR...
Reposted by Andrew Tosolini
Looking forward to AXON2025 - mark your calendars
November 17, 2024 at 10:49 AM
Looking forward to AXON2025 - mark your calendars