Abdou Hachani
abdou-hachani.bsky.social
Abdou Hachani
@abdou-hachani.bsky.social
Microbiologist at the Doherty Institute 🇦🇺
So great to catch up with my incredible mentor and friend Alain Filloux @fillouxlab.bsky.social in Melbourne. #Bacteriology #T6SS
#Pseudomonas #Biofilm
In Melbourne for a symposium organized by the ARC Biofilm Research and Innovation Centre. It was really nice to be welcomed by my colleague and friend @abdou-hachani.bsky.social
November 24, 2025 at 10:54 PM
Reposted by Abdou Hachani
Pleased to share our latest study @natcomms.nature.com! We show that the host metabolites fumarate and itaconate impose selective pressure on Staphylococcus aureus, driving its adaptation via the enzyme FumC. Grateful to all who contributed to this work!
www.nature.com/articles/s41...
Regulation of airway fumarate by host and pathogen promotes Staphylococcus aureus pneumonia - Nature Communications
This study reveals how the pathogen Staphylococcus aureus adapts to the lung microenvironment, rich in host metabolites fumarate and itaconate, by using a key enzyme, FumC, to support its metabolic fi...
www.nature.com
August 1, 2025 at 4:18 AM
Reposted by Abdou Hachani
1/ Excited to share our latest work on gene transfer agents (GTAs) in Caulobacter crescentus, led by Emma Banks in collaboration with Pavol Bardy and Mai Nguyen from York!!! See a brief thread below.
shorturl.at/o6S1w
A bacterial CARD-NLR immune system controls the release of gene transfer agents
Bacteria have evolved a wide array of immune systems to detect and defend against external threats including mobile genetic elements (MGEs) such as bacteriophages, plasmids, and transposons. MGEs are ...
shorturl.at
May 9, 2025 at 8:08 AM
Reposted by Abdou Hachani
Excited to share our preprint demonstrating how fumarate metabolism by host and pathogen promotes pneumonia! Itaconate synergizes with fumarate, driving staphylococcal adaptation for survival. Check it out!👇
www.biorxiv.org/content/10.1...
Regulation of airway fumarate by host and pathogen promotes S. aureus pneumonia
Staphylococcus aureus is a leading cause of healthcare-associated pneumonia, contributing significantly to morbidity and mortality worldwide. As a ubiquitous colonizer of the upper respiratory tract, ...
www.biorxiv.org
April 19, 2025 at 3:42 PM
Reposted by Abdou Hachani
Two ERC-funded postdoc positions available in the team - one here and second to follow - please repost! jobs.ncl.ac.uk/job/Newcastl...
Research Associate Genetic and functional analysis of Gram positive secretion systems and substrates
Research Associate Genetic and functional analysis of Gram positive secretion systems and substrates
jobs.ncl.ac.uk
April 9, 2025 at 12:29 PM
Pushing the boundaries of Nanopore technology while opening new avenues in AMR research. Amazing work from @evamarianovoa.bsky.social
Impressive work from lab of
@evamarianovoa.bsky.social

Scalable and reproducible workflow of native RNA nanopore sequencing + NanoConsensus analysis finds significant rRNA modification changes in response to antibiotic stress—genuinely novel concept for AMR research

www.nature.com/articles/s41...
December 1, 2024 at 11:21 AM