Zach Stevenson
@zachcst.bsky.social
Postdoc, Shendure lab University of Washington/HHMI. Synthetic circuit development.
Ph.D, Phillips Lab University of Oregon. Genetic engineering and experimental evolution.
Zachstevenson.com
Ph.D, Phillips Lab University of Oregon. Genetic engineering and experimental evolution.
Zachstevenson.com
Reposted by Zach Stevenson
I need everybody to read this and understand what’s going on. These are spouses of US citizens in the country legally. They have entry clearance and green cards, they’ve passed background checks and have no criminal records. ICE is taking them anyway.
Gift link:
www.nytimes.com/2025/11/26/u...
Gift link:
www.nytimes.com/2025/11/26/u...
Green Card Interviews End in Handcuffs for Spouses of U.S. Citizens
www.nytimes.com
November 26, 2025 at 8:40 PM
I need everybody to read this and understand what’s going on. These are spouses of US citizens in the country legally. They have entry clearance and green cards, they’ve passed background checks and have no criminal records. ICE is taking them anyway.
Gift link:
www.nytimes.com/2025/11/26/u...
Gift link:
www.nytimes.com/2025/11/26/u...
Reposted by Zach Stevenson
A friend from college texted me asking for advice and this was my first and immediate response.
November 15, 2025 at 10:48 PM
A friend from college texted me asking for advice and this was my first and immediate response.
Reposted by Zach Stevenson
If you're a professor at Texas A&M, you'll need to receive written authorization from the university president before discussing this incident on campus.
November 15, 2025 at 8:18 PM
If you're a professor at Texas A&M, you'll need to receive written authorization from the university president before discussing this incident on campus.
Reposted by Zach Stevenson
Congratulations to Joe Felsenstein on being awarded the 2026 Mendel Medal by the Genetics Society!
genetics.org.uk/medals-and-p...
genetics.org.uk/medals-and-p...
Mendel Medal 2026 - Professor Joe Felsenstein | Genetics Society
The Mendel Medal 2026 has been awarded to Professor Joe Felsenstein. Professor Joe Felsenstein was born in 1942, grew up in Philadelphia and studied as an
genetics.org.uk
November 14, 2025 at 5:57 PM
Congratulations to Joe Felsenstein on being awarded the 2026 Mendel Medal by the Genetics Society!
genetics.org.uk/medals-and-p...
genetics.org.uk/medals-and-p...
Reposted by Zach Stevenson
If you have tenure at Texas A&M and aren't maliciously emailing the president a dozen times every day to ask if you can say this or you can say that, then what's the point in having tenure?
COLLEGE STATION, Texas (AP) — Texas A&M adopts policy requiring professors to get OK from school president to discuss certain race and gender issues.
November 13, 2025 at 11:18 PM
If you have tenure at Texas A&M and aren't maliciously emailing the president a dozen times every day to ask if you can say this or you can say that, then what's the point in having tenure?
Reposted by Zach Stevenson
New preprint!
It turns out you can integrate arrays with super high efficiency using PhiC31.
www.biorxiv.org/content/10.1...
It turns out you can integrate arrays with super high efficiency using PhiC31.
www.biorxiv.org/content/10.1...
High-efficiency targeted integration of extrachromosomal arrays in C. elegans using PhiC31 integrase
Extrachromosomal arrays are unique chromosome-like structures created from DNA injected into the C. elegans germline. Arrays are easy to create and allow for high expression of multiple transgenes. Th...
www.biorxiv.org
November 13, 2025 at 2:59 AM
New preprint!
It turns out you can integrate arrays with super high efficiency using PhiC31.
www.biorxiv.org/content/10.1...
It turns out you can integrate arrays with super high efficiency using PhiC31.
www.biorxiv.org/content/10.1...
Reposted by Zach Stevenson
Stoked to share our latest work entitled: “Large-scale discovery of neural enhancers for cis-regulation therapies”
shorturl.at/H3Qww
This is an enormous team effort that I had the honour of spearheading with Nick Page and Florence Chardon.
Bluetorial below.
shorturl.at/H3Qww
This is an enormous team effort that I had the honour of spearheading with Nick Page and Florence Chardon.
Bluetorial below.
November 5, 2025 at 3:09 PM
Stoked to share our latest work entitled: “Large-scale discovery of neural enhancers for cis-regulation therapies”
shorturl.at/H3Qww
This is an enormous team effort that I had the honour of spearheading with Nick Page and Florence Chardon.
Bluetorial below.
shorturl.at/H3Qww
This is an enormous team effort that I had the honour of spearheading with Nick Page and Florence Chardon.
Bluetorial below.
Reposted by Zach Stevenson
A parts list of promoters and gRNA scaffolds for mammalian genome engineering and molecular recording - @jshendure.bsky.social @troymcdiarmid.bsky.social @uwgenome.bsky.social go.nature.com/49eTPCu
A parts list of promoters and gRNA scaffolds for mammalian genome engineering and molecular recording - Nature Biotechnology
Prime editing in mammalian cells benefits from a comprehensive list of genetic parts.
go.nature.com
November 11, 2025 at 4:36 PM
A parts list of promoters and gRNA scaffolds for mammalian genome engineering and molecular recording - @jshendure.bsky.social @troymcdiarmid.bsky.social @uwgenome.bsky.social go.nature.com/49eTPCu
Reposted by Zach Stevenson
Senate Democrats voting to dismantle the ACA to avoid any problems with their Thanksgiving travel is tragically on brand.
November 9, 2025 at 11:21 PM
Senate Democrats voting to dismantle the ACA to avoid any problems with their Thanksgiving travel is tragically on brand.
Reposted by Zach Stevenson
Reposted by Zach Stevenson
Make males live more than 400% longer and prevent sexual disfunction late in life?! We're down with it. Our latest preprint: Disruption of the insulin signaling pathway in C. elegans dramatically increases male longevity and enhances reproductive health late in life. www.biorxiv.org/content/10.1...
November 6, 2025 at 11:14 PM
Make males live more than 400% longer and prevent sexual disfunction late in life?! We're down with it. Our latest preprint: Disruption of the insulin signaling pathway in C. elegans dramatically increases male longevity and enhances reproductive health late in life. www.biorxiv.org/content/10.1...
Reposted by Zach Stevenson
Finally watched Zohran Mamdani's victory speech and I almost fuckin cried. I got real goosebumps. This is what we need.
Stop listening to the loudest and most out-of-touch pundits screaming about moving to the centre. Be bold and unrelenting in caring about each other.
TURN THE VOLUME UP!
Stop listening to the loudest and most out-of-touch pundits screaming about moving to the centre. Be bold and unrelenting in caring about each other.
TURN THE VOLUME UP!
November 5, 2025 at 8:15 PM
Finally watched Zohran Mamdani's victory speech and I almost fuckin cried. I got real goosebumps. This is what we need.
Stop listening to the loudest and most out-of-touch pundits screaming about moving to the centre. Be bold and unrelenting in caring about each other.
TURN THE VOLUME UP!
Stop listening to the loudest and most out-of-touch pundits screaming about moving to the centre. Be bold and unrelenting in caring about each other.
TURN THE VOLUME UP!
Reposted by Zach Stevenson
Thrilled to share I’ve started my lab at Dartmouth’s Geisel School of Medicine! We focus on mapping cellular trajectories & TF networks in development and Mendelian disorders, exploring new therapies. Join us—postdocs, grads, and scientists welcome! sites.dartmouth.edu/qiulab/
November 4, 2025 at 3:10 PM
Thrilled to share I’ve started my lab at Dartmouth’s Geisel School of Medicine! We focus on mapping cellular trajectories & TF networks in development and Mendelian disorders, exploring new therapies. Join us—postdocs, grads, and scientists welcome! sites.dartmouth.edu/qiulab/
Reposted by Zach Stevenson
Between grants getting politically targeted and my lab’s building getting literally fucking bombed, 2025 is going great thanks
A device exploded inside the Goldenson Building in Harvard’s Longwood medical campus early Saturday morning, according to a message from the Harvard University Police Department to University affiliates.
Matan H. Josephy and Laurel M. Shugart report.
www.thecrimson.com/article/2025...
Matan H. Josephy and Laurel M. Shugart report.
www.thecrimson.com/article/2025...
Authorities Investigating Explosion on Harvard’s Medical Campus, Believed To Be Intentional | News | The Harvard Crimson
A device exploded inside the Goldenson Building in Harvard’s Longwood medical campus early Saturday morning, according to a message from the Harvard University Police Department to University…
www.thecrimson.com
November 1, 2025 at 10:41 PM
Between grants getting politically targeted and my lab’s building getting literally fucking bombed, 2025 is going great thanks
Reposted by Zach Stevenson
Sad day for the folks who staked their reputations on lab leak conspiracy theories.
www.telegraph.co.uk/global-healt...
www.telegraph.co.uk/global-healt...
October 31, 2025 at 3:51 PM
Sad day for the folks who staked their reputations on lab leak conspiracy theories.
www.telegraph.co.uk/global-healt...
www.telegraph.co.uk/global-healt...
Reposted by Zach Stevenson
“Salt Lake County health officials say it’s probable they have found the county’s first measles case since a national outbreak…They say “probable” because the person officials believe is infected has declined to be tested or take part in an investigation, the Salt Lake County Health Department said”
Salt Lake County probably has its first measles case — but the patient is refusing to get tested
Salt Lake County health officials believe there is a likely measles case in the area, the county's first in the current national outbreak. The likely patient, they say, has been unwilling to cooperate...
www.sltrib.com
October 30, 2025 at 2:16 AM
“Salt Lake County health officials say it’s probable they have found the county’s first measles case since a national outbreak…They say “probable” because the person officials believe is infected has declined to be tested or take part in an investigation, the Salt Lake County Health Department said”
Reposted by Zach Stevenson
I'm shaking almost too hard to type. I entered SLC airport and heard screams and cries for help. I could see people gathered around, watching. I sped over to discover this woman face down on the floor, four grown men pushing her down, while she cried "HELP ME" and pled for her child.
October 29, 2025 at 10:23 PM
I'm shaking almost too hard to type. I entered SLC airport and heard screams and cries for help. I could see people gathered around, watching. I sped over to discover this woman face down on the floor, four grown men pushing her down, while she cried "HELP ME" and pled for her child.
Reposted by Zach Stevenson
The Python Software Foundation was recommended for a $1.5M grant from the National Science Foundation. The terms of the award said PSF could not work on DEI, whether or not the grant funding was used for it.
PSF therefore declined the funding.
Science suffers, but commitment to core values remains
PSF therefore declined the funding.
Science suffers, but commitment to core values remains
TLDR; The PSF has made the decision to put our community and our shared diversity, equity, and inclusion values ahead of seeking $1.5M in new revenue. Please read and share. pyfound.blogspot.com/2025/10/NSF-...
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The official home of the Python Programming Language
www.python.org
October 27, 2025 at 5:31 PM
The Python Software Foundation was recommended for a $1.5M grant from the National Science Foundation. The terms of the award said PSF could not work on DEI, whether or not the grant funding was used for it.
PSF therefore declined the funding.
Science suffers, but commitment to core values remains
PSF therefore declined the funding.
Science suffers, but commitment to core values remains
Reposted by Zach Stevenson
Today @anthropic.com released PubMed integration for Claude. No hallucinations. Just real science, real data. As a beta tester, this has been game changing— a supercharged research tool. Here are 6 prompts that will transform how you search the literature. A 🧵
www.anthropic.com/news/claude-...
www.anthropic.com/news/claude-...
Claude for Life Sciences
Discover how Claude accelerates life sciences research with new scientific connectors, skills, and improved performance for drug discovery and clinical work.
www.anthropic.com
October 20, 2025 at 5:27 PM
Today @anthropic.com released PubMed integration for Claude. No hallucinations. Just real science, real data. As a beta tester, this has been game changing— a supercharged research tool. Here are 6 prompts that will transform how you search the literature. A 🧵
www.anthropic.com/news/claude-...
www.anthropic.com/news/claude-...
Reposted by Zach Stevenson
WOW! Our survey of scientists who stopped using Twitter and started using Bluesky is now the #1 most-shared on social media article in the history of the journal Integrative and Comparative Biology! Thanks for reading it, everyone! @sicbjournals.bsky.social
doi.org/10.1093/icb/... 🧪
doi.org/10.1093/icb/... 🧪
Scientists no Longer Find Twitter Professionally Useful, and have Switched to Bluesky
Synopsis. Social media has become widely used by the scientific community for a variety of professional uses, including networking and public outreach. For
doi.org
October 15, 2025 at 7:29 PM
WOW! Our survey of scientists who stopped using Twitter and started using Bluesky is now the #1 most-shared on social media article in the history of the journal Integrative and Comparative Biology! Thanks for reading it, everyone! @sicbjournals.bsky.social
doi.org/10.1093/icb/... 🧪
doi.org/10.1093/icb/... 🧪
Reposted by Zach Stevenson
As a science communicator who built my professional career out of understanding "Science Twitter":
I'm confident Bluesky will be the scientific community's social media home for a while
Tell your friends at #ASHG25 to get over here, whether they're on X or not!
I'm confident Bluesky will be the scientific community's social media home for a while
Tell your friends at #ASHG25 to get over here, whether they're on X or not!
WOW! Our survey of scientists who stopped using Twitter and started using Bluesky is now the #1 most-shared on social media article in the history of the journal Integrative and Comparative Biology! Thanks for reading it, everyone! @sicbjournals.bsky.social
doi.org/10.1093/icb/... 🧪
doi.org/10.1093/icb/... 🧪
Scientists no Longer Find Twitter Professionally Useful, and have Switched to Bluesky
Synopsis. Social media has become widely used by the scientific community for a variety of professional uses, including networking and public outreach. For
doi.org
October 16, 2025 at 1:39 AM
As a science communicator who built my professional career out of understanding "Science Twitter":
I'm confident Bluesky will be the scientific community's social media home for a while
Tell your friends at #ASHG25 to get over here, whether they're on X or not!
I'm confident Bluesky will be the scientific community's social media home for a while
Tell your friends at #ASHG25 to get over here, whether they're on X or not!
Reposted by Zach Stevenson
Against Publishing: universonline.nl/nieuws/2025/...
Preprints are read, shared, and cited, yet still dismissed as incomplete until blessed by a publisher. I argue that the true measure of scholarship lies in open exchange, not in the industry’s gatekeeping of what counts as published.
Preprints are read, shared, and cited, yet still dismissed as incomplete until blessed by a publisher. I argue that the true measure of scholarship lies in open exchange, not in the industry’s gatekeeping of what counts as published.
October 14, 2025 at 9:16 AM
Against Publishing: universonline.nl/nieuws/2025/...
Preprints are read, shared, and cited, yet still dismissed as incomplete until blessed by a publisher. I argue that the true measure of scholarship lies in open exchange, not in the industry’s gatekeeping of what counts as published.
Preprints are read, shared, and cited, yet still dismissed as incomplete until blessed by a publisher. I argue that the true measure of scholarship lies in open exchange, not in the industry’s gatekeeping of what counts as published.
Reposted by Zach Stevenson
Super excited about first Shendure/Baker Lab collaboration & preprint on a multiplex sequencing-based strategy for screening de novo proteome editors in mammalian cells. Kudos to the brilliant Chase Suiter (not here) & @greenahn.bsky.social on the work! Preprint here:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
October 14, 2025 at 6:45 PM
Super excited about first Shendure/Baker Lab collaboration & preprint on a multiplex sequencing-based strategy for screening de novo proteome editors in mammalian cells. Kudos to the brilliant Chase Suiter (not here) & @greenahn.bsky.social on the work! Preprint here:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Zach Stevenson
Kristi Noem’s America, folks. That poor dog. That poor family.
October 12, 2025 at 6:13 PM
Kristi Noem’s America, folks. That poor dog. That poor family.
Reposted by Zach Stevenson
No words
May 30, 2025 at 12:23 PM
No words