Wenqi ‘Vince’ Liu
vincentchemistry.bsky.social
Wenqi ‘Vince’ Liu
@vincentchemistry.bsky.social
Assistant professor of Supramolecular Organic Chemistry at the University of South Florida www.vincentchemistry.com
Reposted by Wenqi ‘Vince’ Liu
Should You Really be Writing A(nother) Review Manuscript?
An editorial in the new issue of ACS Energy Articles discusses the relevance of Review Articles in the era of AI.
pubs.acs.org/doi/10.1021/...
October 10, 2025 at 11:35 AM
Happy to share our work on synthetic lectins for glucuronate featured as cover art! @pubs.acs.org #MyACSCover bit.ly/4o8oA0S
September 24, 2025 at 3:01 PM
Proud to share our new paper in ACS Central Science! We show that hydrogen bonding—often considered ineffective in water—can enable strong, selective binding of the hydrophilic carbohydrate glucuronate, when combined with [C–H···π] and electrostatic interactions. bit.ly/4o8oA0S
August 1, 2025 at 7:04 PM
Reposted by Wenqi ‘Vince’ Liu
Our latest paper shows emissive organic cations can be brought together by certain counterions, giving emission from the monomer, excimer or dimer state

onlinelibrary.wiley.com/doi/10.1002/...
Counterion‐Mediated Luminophore Dimerization
Emissive organic salts have long been integral to the discovery of fluorescence phenomena and functional luminescent dyes. Typically, one component of the salt acts as the photoactive unit (luminopho...
onlinelibrary.wiley.com
June 24, 2025 at 10:12 PM
Reposted by Wenqi ‘Vince’ Liu
First page of Irving Langmuir's laboratory notebook from his time at Göttingen, where he obtained his PhD with Nernst. Dated 6 August 1904. Image was taken at the U.S. Library of Congress (yes it's still open).
June 28, 2025 at 3:20 AM
In collaboration with Prof. Hongliang Chen, we reported perylene diimide-based molecular wires encapsulated by XCage, which effectively insulates the molecular wire, suppressing charge disturbance and shielding radiation within its interior, making it a molecular-scale Faraday cage. bit.ly/4jnOkmj
May 30, 2025 at 12:55 PM
Check out our latest work @chemistryeurope.bsky.social
on a dicationic tetralactam macrocycle that binds hydrophilic sulfate in water. Structural and thermodynamic studies highlight the critical roles of H-bonding, electrostatics, and water release in overcoming desolvation barriers. bit.ly/4ky5QFH
May 20, 2025 at 2:34 PM
Reposted by Wenqi ‘Vince’ Liu
Binding hydrophilic molecules is challenging due to high hydration energy. So why not bind them with their water? Our work (the Cai group at USF and us) shows a flexible proline cage capturing fluoride along with its hydration shell with strong affinity. www.nature.com/articles/s41...
Proline-based tripodal cages with guest-adaptive features for capturing hydrophilic and amphiphilic fluoride substances - Nature Communications
Proteins dynamically adjust their conformations to interact with their ligands through binding sites that accommodate either amphiphilic or hydrophilic substrates, but most synthetic receptors are des...
www.nature.com
April 5, 2025 at 2:10 PM
Reposted by Wenqi ‘Vince’ Liu
Big congrats to Qingkay & the Zhang group team (@ncstate.bsky.social) on the new @jacs.acspublications.org article! 🎉🧪 We show how tuning hydrazone emission leads to fluorogenic PALM probes unlocking high-res live-cell plasma membrane imaging. 🔬✨

Check it out 👉 bit.ly/3EKwxHT
#MolSwitch #ChemSky ⚗️💡
Photoswitchable Fluorescent Hydrazone for Super-Resolution Cell Membrane Imaging
Advancing the field of super-resolution microscopy will require the design and optimization of new molecular probes whose emission can be toggled “ON” and “OFF” using light. Recently, we reported on a...
bit.ly
May 3, 2025 at 3:01 PM
Reposted by Wenqi ‘Vince’ Liu
Click chemistry is a powerful way to stitch molecules together — but in our new @jacs.acspublications.org paper bit.ly/4cNBqMK we find that not all triazoles are equal! When it comes to #photoswitch the 1,5-regioisomer (not from "click") surprisingly outperforms the classic 1,4🧪⚗️ #molswitch #chemsky
“Clicked” Hydrazone Photoswitches
The length of the linker connecting a photoswitch to a material significantly influences the latter’s properties, with “zero-length” linkers being ideal for optimal photomodulation. The 1,2,3-triazole...
bit.ly
April 26, 2025 at 8:23 PM
Glad to see our work on charge assisted hydrogen bonding for anion recognition in water is selected as the 2024 most polular articles by @chemicalscience.rsc.org. Check it out: rsc.li/4dgwyOI
April 9, 2025 at 3:49 PM
Excited to see our mini review featured as the front cover of @cp-trendschem.bsky.social . The cover art illustrates hydrogen bonding receptors making a splash in water, highlighting the growing significance and exciting opportunities of this emerging field in supramolecular chemistry.
🌊 We're making a splash with the February issue of Trends in Chemistry, online now! Our cover article comes from @vincentchemistry.bsky.social and team, reviewing recent progress in designing receptors that form strong and selective hydrogen bonds with guests in water:
www.cell.com/trends/chemi...
February 13, 2025 at 2:06 PM
Reposted by Wenqi ‘Vince’ Liu
Very pleased that my first post presents these affinity tunable partially sulfated pillar[5]arenes lead by Ayona Goswami. chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
Partially Sulfated Pillar[5]Arenes: Synthesis and Molecular Recognition Properties
A series of pillar[5]arene sulfates P5Sn with different numbers of sulfate ionic groups are synthesized and fully characterized by spectroscopic, crystallographic, and computational methods. Isotherm...
chemistry-europe.onlinelibrary.wiley.com
January 22, 2025 at 1:54 PM
Reposted by Wenqi ‘Vince’ Liu
The US Department of Energy (DOE) has committed to a $1.4 billion loan for a project that will use an emerging technology to separate lithium from geothermal brines in California. cen.acs.org/energy/energ...
US bets on new lithium extraction technology
Department of Energy commits to $1.4 billion loan for small California firm
cen.acs.org
January 22, 2025 at 7:31 PM
Reposted by Wenqi ‘Vince’ Liu
Twelve identical helical macrocycles assemble to form this right-handed snub cube supramolecule. The new snub cube supramolecules’ creators say they could be used for chiral separations or asymmetric catalysis: cen.acs.org/materials/na... #chemsky🧪 #scinews
January 20, 2025 at 7:03 PM
Reposted by Wenqi ‘Vince’ Liu
Check out this supramolecular snub cube. Cool chemistry from Huang Wu and the late Fraser Stoddart of the University of Hong Kong along with Wenping Hu and Yu Wang of Tianjin University. My latest in @cenmag.bsky.social cen.acs.org/materials/na...
January 8, 2025 at 6:00 PM
Reposted by Wenqi ‘Vince’ Liu
In his last email to me just before Xmass, Fraser asked me to keep an eye for this @nature.com paper (www.nature.com/articles/s41...). It is "a blockbuster in my humble opinion" eh added. His excitement about the project and pride in the students who work on it for 5 years was palpable. RIP Fraser
January 9, 2025 at 2:20 PM
Check out our review @cp-trendschem.bsky.social on recent advances in synthetic hydrogen bonding receptors in water—mimicking nature's precision in aqueous molecular recognition. Dedicated to Sir Fraser Stoddart and Dr. Wei Jiang for their unwavering support and enduring inspiration. bit.ly/3C6GBK0
January 12, 2025 at 4:20 AM
Reposted by Wenqi ‘Vince’ Liu
A more extensive news story from Northwestern about Fraser 👇 #Chemsky
Sir Fraser Stoddart, a pioneer in nanoscience, dies at 82
Stoddart received the 2016 Nobel Prize in Chemistry for work on molecular machines
news.northwestern.edu
January 2, 2025 at 6:08 PM
Reposted by Wenqi ‘Vince’ Liu
Our 3D volumetric display is on the front cover of the December issue of Chem! Congrats to all involved including awesome collaborator @alexlippert.bsky.social 🧪⚗️#molswitch #photoswitches bit.ly/4ckn44N
December 13, 2024 at 8:14 PM
Reposted by Wenqi ‘Vince’ Liu
A second paper on tuberculosis vaccines! Here, we present two new transmembrane protein antigens in a proteoliposome. Proteoliposomes are too delicate for a TB vaccine, so, of course, we cover them in MOFs. Shena (probably not on Bsky) showcases her work on that other site:
December 14, 2024 at 2:01 AM
Reposted by Wenqi ‘Vince’ Liu

How to write a grant?
1. The application is for the reviewer, not you, the applicant.
2. Communicate in stories.
3. Make your story cohesive—leave no puzzling gaps.
4. Make your story resonate to keep the reviewer reading.
5. Accept chance and noise in peer-review.
www.pnas.org/doi/epub/10....
November 24, 2024 at 3:38 PM
Reposted by Wenqi ‘Vince’ Liu
A huge thanks to @natureportfolio.bsky.social for shining a light on the often-overlooked issue of #snakebite #envenoming and our recombinant #antivenom research at the Center for Antibody Technologies at the Technical University of Denmark. Check out the article here: www.nature.com/articles/d41...
Next-generation snakebite therapies could reduce death toll
Venomous snakes kill tens of thousands of people each year. Treatments that are simpler to administer and more effective than conventional antivenom could curb this number.
www.nature.com
November 22, 2024 at 1:29 PM
Reposted by Wenqi ‘Vince’ Liu
#Myfirstpost and looking to reconnect with the #chemsky! My group is interested in organic supramolecular chemistry and stimuli-responsive crystalline solids. Last year we moved to the University of Missouri Department of Chemistry (chemistry.missouri.edu) and MatSci (msei.missouri.edu/)!
MU Materials Science & Engineering Institute
msei.missouri.edu
November 19, 2024 at 10:08 PM