Ulvmar lab
@ulvmarlab.bsky.social
My team aims to expand the current knowledge about the lymph node vascular specialization and its changes in cancer & in aging -https://www.uu.se/en/department/medical-biochemistry-and-microbiology/research/ulvmar-maria - #lymphatics #metastasis #stroma
Reposted by Ulvmar lab
New paper alert 🚨
We are delighted to present our latest paper in @natcomms.nature.com through fabulous work from co-first authors Sebastian Braun and Paulina Bolivar! Big thanks to all expert collaborators for taking this long journey with us!
Tweetorial in comments 🧵
www.nature.com/articles/s41...
We are delighted to present our latest paper in @natcomms.nature.com through fabulous work from co-first authors Sebastian Braun and Paulina Bolivar! Big thanks to all expert collaborators for taking this long journey with us!
Tweetorial in comments 🧵
www.nature.com/articles/s41...
Pericytes orchestrate a tumor-restraining microenvironment in glioblastoma - Nature Communications
Improved understanding of the tumor ecosystem in glioblastoma is critical for developing new treatment strategies for the disease. Here, the authors identify pericytes as an active paracrine signaling...
www.nature.com
December 9, 2025 at 5:05 PM
New paper alert 🚨
We are delighted to present our latest paper in @natcomms.nature.com through fabulous work from co-first authors Sebastian Braun and Paulina Bolivar! Big thanks to all expert collaborators for taking this long journey with us!
Tweetorial in comments 🧵
www.nature.com/articles/s41...
We are delighted to present our latest paper in @natcomms.nature.com through fabulous work from co-first authors Sebastian Braun and Paulina Bolivar! Big thanks to all expert collaborators for taking this long journey with us!
Tweetorial in comments 🧵
www.nature.com/articles/s41...
Reposted by Ulvmar lab
🌟14th EFIS-EJI TATRA Immunology Conference
💡Proudly supported by #EFIS and @eurjimmunol.bsky.social
🤝organized by the 🇦🇹,🇨🇿+🇸🇰 Immunological Societies
📚unites Europe’s rising #immunology stars since 1994
👉 tatra.img.cas.cz
Be part of this community shaping the future of immunology & spread the word!
💡Proudly supported by #EFIS and @eurjimmunol.bsky.social
🤝organized by the 🇦🇹,🇨🇿+🇸🇰 Immunological Societies
📚unites Europe’s rising #immunology stars since 1994
👉 tatra.img.cas.cz
Be part of this community shaping the future of immunology & spread the word!
January 21, 2026 at 8:38 AM
🌟14th EFIS-EJI TATRA Immunology Conference
💡Proudly supported by #EFIS and @eurjimmunol.bsky.social
🤝organized by the 🇦🇹,🇨🇿+🇸🇰 Immunological Societies
📚unites Europe’s rising #immunology stars since 1994
👉 tatra.img.cas.cz
Be part of this community shaping the future of immunology & spread the word!
💡Proudly supported by #EFIS and @eurjimmunol.bsky.social
🤝organized by the 🇦🇹,🇨🇿+🇸🇰 Immunological Societies
📚unites Europe’s rising #immunology stars since 1994
👉 tatra.img.cas.cz
Be part of this community shaping the future of immunology & spread the word!
Reposted by Ulvmar lab
Today is #WorldCancerDay
~1 in 5 people will develop #cancer in their lifetime
Each diagnosis affects not just one person, but families, communities, and futures
Grateful today for patients, clinicians, researchers & advocates - and to appreciate that progress depends on acting together
#WCD2026
~1 in 5 people will develop #cancer in their lifetime
Each diagnosis affects not just one person, but families, communities, and futures
Grateful today for patients, clinicians, researchers & advocates - and to appreciate that progress depends on acting together
#WCD2026
February 4, 2026 at 11:45 AM
Today is #WorldCancerDay
~1 in 5 people will develop #cancer in their lifetime
Each diagnosis affects not just one person, but families, communities, and futures
Grateful today for patients, clinicians, researchers & advocates - and to appreciate that progress depends on acting together
#WCD2026
~1 in 5 people will develop #cancer in their lifetime
Each diagnosis affects not just one person, but families, communities, and futures
Grateful today for patients, clinicians, researchers & advocates - and to appreciate that progress depends on acting together
#WCD2026
Reposted by Ulvmar lab
A key finding of our last study is that soluble and immobilized CCL21 gradients cooperate to fine-tune different steps of lymphatic migration, revealing a new layer in leukocyte guidance.
This work was only possible thanks to an amazing team effort!
This work was only possible thanks to an amazing team effort!
uPA-mediated remodeling of CCL21 gradients regulates lymphatic migration of dendritic cells. New study from Victor Collado-Diaz, Maria-Nefeli Christakopoulou, Philipp Schineis, Cornelia Halin @halinlab.bsky.social @ethz.ch and colleagues: rupress.org/jcb/article/...
#Immunology #Migration #motility
#Immunology #Migration #motility
February 4, 2026 at 8:29 AM
A key finding of our last study is that soluble and immobilized CCL21 gradients cooperate to fine-tune different steps of lymphatic migration, revealing a new layer in leukocyte guidance.
This work was only possible thanks to an amazing team effort!
This work was only possible thanks to an amazing team effort!
Reposted by Ulvmar lab
uPA-mediated remodeling of CCL21 gradients regulates lymphatic migration of dendritic cells. New study from Victor Collado-Diaz, Maria-Nefeli Christakopoulou, Philipp Schineis, Cornelia Halin @halinlab.bsky.social @ethz.ch and colleagues: rupress.org/jcb/article/...
#Immunology #Migration #motility
#Immunology #Migration #motility
February 3, 2026 at 3:30 PM
uPA-mediated remodeling of CCL21 gradients regulates lymphatic migration of dendritic cells. New study from Victor Collado-Diaz, Maria-Nefeli Christakopoulou, Philipp Schineis, Cornelia Halin @halinlab.bsky.social @ethz.ch and colleagues: rupress.org/jcb/article/...
#Immunology #Migration #motility
#Immunology #Migration #motility
Reposted by Ulvmar lab
An update to the Hallmarks of Cancer framework for understanding (and researching) what causes human cancers. spkl.io/63321Aqwbc
Douglas Hanahan
@cp-cell.bsky.social
Douglas Hanahan
@cp-cell.bsky.social
January 29, 2026 at 5:00 PM
An update to the Hallmarks of Cancer framework for understanding (and researching) what causes human cancers. spkl.io/63321Aqwbc
Douglas Hanahan
@cp-cell.bsky.social
Douglas Hanahan
@cp-cell.bsky.social
Reposted by Ulvmar lab
Nature research paper: Fibroblastic reticular cells direct the initiation of T cell responses via CD44
go.nature.com/4qxGBXl
go.nature.com/4qxGBXl
Fibroblastic reticular cells direct the initiation of T cell responses via CD44 - Nature
CD44 expressed by fibroblastic reticular cells in secondary lymphoid organs regulates trafficking of dendritic cells, and thus has an essential role in the priming of T cells and the adaptive immune response.
go.nature.com
January 27, 2026 at 9:08 AM
Nature research paper: Fibroblastic reticular cells direct the initiation of T cell responses via CD44
go.nature.com/4qxGBXl
go.nature.com/4qxGBXl
Reposted by Ulvmar lab
Fibroblastic reticular cells direct the initiation of T cell responses via CD44 @nature.com @the-de-lab.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
January 21, 2026 at 6:06 PM
Fibroblastic reticular cells direct the initiation of T cell responses via CD44 @nature.com @the-de-lab.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Ulvmar lab
We’re delighted to see this out today! Latest work from the lab reveals insights into the evolution of brain immunity and the developmental and evolutionary plasticity of lymphatic endothelial cells.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Convergent evolution of scavenger cell development at brain borders - Nature
Transcription factor osr2 is identified as a specific marker and regulator of mural lymphatic endothelial cell (muLEC) differentiation and maintenance, and muLECs and border-associated macrophages sha...
www.nature.com
January 21, 2026 at 8:42 PM
We’re delighted to see this out today! Latest work from the lab reveals insights into the evolution of brain immunity and the developmental and evolutionary plasticity of lymphatic endothelial cells.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Ulvmar lab
New paper out from the @kpietraslab.bsky.social lab.
I am happy to share that my first-author paper is now published. We map the spatial and temporal dynamics of cancer-associated fibroblasts in breast cancer using integrated spatial proteomics and transcriptomics.
link.springer.com/article/10.1...
I am happy to share that my first-author paper is now published. We map the spatial and temporal dynamics of cancer-associated fibroblasts in breast cancer using integrated spatial proteomics and transcriptomics.
link.springer.com/article/10.1...
Spatial and temporal dynamics of cancer-associated fibroblast niches in breast cancer - Breast Cancer Research
Breast Cancer Research - Cancer-associated fibroblasts (CAFs) are the main constituents of the tumor microenvironment. Several studies have delineated CAF heterogeneity in different types of...
link.springer.com
January 17, 2026 at 12:04 PM
New paper out from the @kpietraslab.bsky.social lab.
I am happy to share that my first-author paper is now published. We map the spatial and temporal dynamics of cancer-associated fibroblasts in breast cancer using integrated spatial proteomics and transcriptomics.
link.springer.com/article/10.1...
I am happy to share that my first-author paper is now published. We map the spatial and temporal dynamics of cancer-associated fibroblasts in breast cancer using integrated spatial proteomics and transcriptomics.
link.springer.com/article/10.1...
Danish PhDs - possibility to join Uppsala University as postdoc! Deadline 29th of Jan - My lab has an open project for a candidate who wants to study how the specialized vascular and stromal cells in lymph nodes shape the immune response in aging & cancer.
novonordiskfonden.dk/en/grant/pos...
novonordiskfonden.dk/en/grant/pos...
Postdoctoral Fellowships at Uppsala University - 2026 - Novo Nordisk Fonden
novonordiskfonden.dk
January 8, 2026 at 1:35 PM
Danish PhDs - possibility to join Uppsala University as postdoc! Deadline 29th of Jan - My lab has an open project for a candidate who wants to study how the specialized vascular and stromal cells in lymph nodes shape the immune response in aging & cancer.
novonordiskfonden.dk/en/grant/pos...
novonordiskfonden.dk/en/grant/pos...
Reposted by Ulvmar lab
Oscillatory shear-activated mTORC1 in Lymphatic Valve Morphogenesis & Homeostasis
Adult 🐭mesenteric Lymphatic Valve EC is more proliferative than capillary EC, indie of VEGFA/C
Flt4+ LEC Tsc1 KO in P1-5🐭➡️⏫Valve size/density at P10
@petrovalab.bsky.social #JCB 2023
rupress.org/jcb/article/...
Adult 🐭mesenteric Lymphatic Valve EC is more proliferative than capillary EC, indie of VEGFA/C
Flt4+ LEC Tsc1 KO in P1-5🐭➡️⏫Valve size/density at P10
@petrovalab.bsky.social #JCB 2023
rupress.org/jcb/article/...
January 4, 2026 at 11:49 AM
Oscillatory shear-activated mTORC1 in Lymphatic Valve Morphogenesis & Homeostasis
Adult 🐭mesenteric Lymphatic Valve EC is more proliferative than capillary EC, indie of VEGFA/C
Flt4+ LEC Tsc1 KO in P1-5🐭➡️⏫Valve size/density at P10
@petrovalab.bsky.social #JCB 2023
rupress.org/jcb/article/...
Adult 🐭mesenteric Lymphatic Valve EC is more proliferative than capillary EC, indie of VEGFA/C
Flt4+ LEC Tsc1 KO in P1-5🐭➡️⏫Valve size/density at P10
@petrovalab.bsky.social #JCB 2023
rupress.org/jcb/article/...
Reposted by Ulvmar lab
One of the most-viewed PNAS articles in the last week is “Tattoo ink induces inflammation in the draining lymph node and alters the immune response to vaccination.” Explore the article here: https://ow.ly/zhn450XGvmW
For more trending articles, visit https://ow.ly/7BgF50XGvmV.
For more trending articles, visit https://ow.ly/7BgF50XGvmV.
December 10, 2025 at 12:30 AM
One of the most-viewed PNAS articles in the last week is “Tattoo ink induces inflammation in the draining lymph node and alters the immune response to vaccination.” Explore the article here: https://ow.ly/zhn450XGvmW
For more trending articles, visit https://ow.ly/7BgF50XGvmV.
For more trending articles, visit https://ow.ly/7BgF50XGvmV.
Reposted by Ulvmar lab
Comparative analysis of commercial Imaging-based #SpatialTranscriptomics methods
Xenium
CosMx 1k
MERSCOPE
Tissue Microarray
17 tumor+16 normal tissue
Transcript count
vs Reference RNAseq
Segmentation accuracy
Cell type annotation
#NatComms 2025
www.nature.com/articles/s41...
Xenium
CosMx 1k
MERSCOPE
Tissue Microarray
17 tumor+16 normal tissue
Transcript count
vs Reference RNAseq
Segmentation accuracy
Cell type annotation
#NatComms 2025
www.nature.com/articles/s41...
December 1, 2025 at 12:52 PM
Comparative analysis of commercial Imaging-based #SpatialTranscriptomics methods
Xenium
CosMx 1k
MERSCOPE
Tissue Microarray
17 tumor+16 normal tissue
Transcript count
vs Reference RNAseq
Segmentation accuracy
Cell type annotation
#NatComms 2025
www.nature.com/articles/s41...
Xenium
CosMx 1k
MERSCOPE
Tissue Microarray
17 tumor+16 normal tissue
Transcript count
vs Reference RNAseq
Segmentation accuracy
Cell type annotation
#NatComms 2025
www.nature.com/articles/s41...
Reposted by Ulvmar lab
Kurz, Lütge, Ludewig et al. elucidate the ontogeny of fibroblastic reticular cells and vascular smooth muscle cells in mouse lymph nodes from proliferating, CCL19-expressing progenitors & highlight the close lineage relationship of the progeny in the perivascular niche rupress.org/jem/article/...
November 26, 2025 at 6:02 PM
Kurz, Lütge, Ludewig et al. elucidate the ontogeny of fibroblastic reticular cells and vascular smooth muscle cells in mouse lymph nodes from proliferating, CCL19-expressing progenitors & highlight the close lineage relationship of the progeny in the perivascular niche rupress.org/jem/article/...
Reposted by Ulvmar lab
Big news, EVBO community!
Our BLACK FRIDAY membership deal is live until 31 Dec 2025:
🔹 3-year full membership: €120
🔹 PhD/postdoc: €75
Join now ➜ evbo.org/index.php/me...
Plus, members get access to 3 exclusive vascular biology workshops in 2026. Don’t miss out!
Our BLACK FRIDAY membership deal is live until 31 Dec 2025:
🔹 3-year full membership: €120
🔹 PhD/postdoc: €75
Join now ➜ evbo.org/index.php/me...
Plus, members get access to 3 exclusive vascular biology workshops in 2026. Don’t miss out!
Membership - European Vascular Biology Organisation
EVBO needs your support to further expand its activities and invites you to become a member.EVBO develops scientific, educational, training and networking activities to potentiate vascular biologists…
evbo.org
November 27, 2025 at 11:48 AM
Big news, EVBO community!
Our BLACK FRIDAY membership deal is live until 31 Dec 2025:
🔹 3-year full membership: €120
🔹 PhD/postdoc: €75
Join now ➜ evbo.org/index.php/me...
Plus, members get access to 3 exclusive vascular biology workshops in 2026. Don’t miss out!
Our BLACK FRIDAY membership deal is live until 31 Dec 2025:
🔹 3-year full membership: €120
🔹 PhD/postdoc: €75
Join now ➜ evbo.org/index.php/me...
Plus, members get access to 3 exclusive vascular biology workshops in 2026. Don’t miss out!
Reposted by Ulvmar lab
It was a great pleasure to be a part of this new study from @halinlab.bsky.social focusing on the #Lymphatics in human skin!
Transcriptomics- and 3D imaging-based characterization of the lymphatic vasculature in human skin. New study from Aline Bauer, Cornelia Halin and colleagues @ethz.ch: rupress.org/jem/article/...
#CardiovascularBiology #InnateImmunity #inflammation #Lymphatics
#CardiovascularBiology #InnateImmunity #inflammation #Lymphatics
November 16, 2025 at 12:14 AM
It was a great pleasure to be a part of this new study from @halinlab.bsky.social focusing on the #Lymphatics in human skin!
Reposted by Ulvmar lab
Our @natcomms.nature.com paper is finally out! 🚀 rdcu.be/eQnYW
Using scRNA-seq and Visium HD, we mapped lymphatics in metastatic lymph nodes from breast cancer patients and discovered striking lymphatic remodeling that shapes subsequent metastasis.
Massive thanks to all collaborators!!!
Using scRNA-seq and Visium HD, we mapped lymphatics in metastatic lymph nodes from breast cancer patients and discovered striking lymphatic remodeling that shapes subsequent metastasis.
Massive thanks to all collaborators!!!
November 17, 2025 at 5:47 PM
Our @natcomms.nature.com paper is finally out! 🚀 rdcu.be/eQnYW
Using scRNA-seq and Visium HD, we mapped lymphatics in metastatic lymph nodes from breast cancer patients and discovered striking lymphatic remodeling that shapes subsequent metastasis.
Massive thanks to all collaborators!!!
Using scRNA-seq and Visium HD, we mapped lymphatics in metastatic lymph nodes from breast cancer patients and discovered striking lymphatic remodeling that shapes subsequent metastasis.
Massive thanks to all collaborators!!!
Reposted by Ulvmar lab
Do Not miss this great @navbo.bsky.social online event😆
Specification of Endothelial Cell Phenotypes
Organized by Dr. Ralf Adams @ralfhadams.bsky.social
& Dr. Vicki Bautch
Abstract deadline November 20
members.navbo.org/calendar-of-...
Specification of Endothelial Cell Phenotypes
Organized by Dr. Ralf Adams @ralfhadams.bsky.social
& Dr. Vicki Bautch
Abstract deadline November 20
members.navbo.org/calendar-of-...
November 13, 2025 at 7:51 PM
Do Not miss this great @navbo.bsky.social online event😆
Specification of Endothelial Cell Phenotypes
Organized by Dr. Ralf Adams @ralfhadams.bsky.social
& Dr. Vicki Bautch
Abstract deadline November 20
members.navbo.org/calendar-of-...
Specification of Endothelial Cell Phenotypes
Organized by Dr. Ralf Adams @ralfhadams.bsky.social
& Dr. Vicki Bautch
Abstract deadline November 20
members.navbo.org/calendar-of-...
Reposted by Ulvmar lab
Check out our new study in @jem.org on #Lymphatics using #SingleCell and #3DImaging in human skin, revealing new features of the lymphatic vascular system in #HumanBiology!
Transcriptomics- and 3D imaging-based characterization of the lymphatic vasculature in human skin. New study from Aline Bauer, Cornelia Halin and colleagues @ethz.ch: rupress.org/jem/article/...
#CardiovascularBiology #InnateImmunity #inflammation #Lymphatics
#CardiovascularBiology #InnateImmunity #inflammation #Lymphatics
November 15, 2025 at 10:25 PM
Check out our new study in @jem.org on #Lymphatics using #SingleCell and #3DImaging in human skin, revealing new features of the lymphatic vascular system in #HumanBiology!
Reposted by Ulvmar lab
Reformation of science publishing: the Stockholm Declaration
A call to action for universities, academies, science organizations and funders to unite and join this effort.
Bernhard Sabel and Dan Larhammar
royalsocietypublishing.org/doi/10.1098/...
A call to action for universities, academies, science organizations and funders to unite and join this effort.
Bernhard Sabel and Dan Larhammar
royalsocietypublishing.org/doi/10.1098/...
Reformation of science publishing: the Stockholm Declaration | Royal Society Open Science
Science relies on integrity and trustworthiness. But scientists under career pressure
are lured to purchase fake publications from ‘paper mills’ that use AI-generated data,
text and image fabrication....
royalsocietypublishing.org
November 9, 2025 at 8:43 PM
Reformation of science publishing: the Stockholm Declaration
A call to action for universities, academies, science organizations and funders to unite and join this effort.
Bernhard Sabel and Dan Larhammar
royalsocietypublishing.org/doi/10.1098/...
A call to action for universities, academies, science organizations and funders to unite and join this effort.
Bernhard Sabel and Dan Larhammar
royalsocietypublishing.org/doi/10.1098/...
Reposted by Ulvmar lab
Transcriptomics- and 3D imaging-based characterization of the lymphatic vasculature in human skin. New study from Aline Bauer, Cornelia Halin and colleagues @ethz.ch: rupress.org/jem/article/...
#CardiovascularBiology #InnateImmunity #inflammation #Lymphatics
#CardiovascularBiology #InnateImmunity #inflammation #Lymphatics
November 11, 2025 at 2:45 PM
Transcriptomics- and 3D imaging-based characterization of the lymphatic vasculature in human skin. New study from Aline Bauer, Cornelia Halin and colleagues @ethz.ch: rupress.org/jem/article/...
#CardiovascularBiology #InnateImmunity #inflammation #Lymphatics
#CardiovascularBiology #InnateImmunity #inflammation #Lymphatics
Reposted by Ulvmar lab
New study from Bauer, Halin et al. @ethz.ch reveals how the structure and cellular morphology of human dermal afferent lymphatic vessels differ from the current, primarily mouse tissue–based textbook description. rupress.org/jem/article/...
#Lymphatics
#Lymphatics
November 4, 2025 at 5:00 PM
New study from Bauer, Halin et al. @ethz.ch reveals how the structure and cellular morphology of human dermal afferent lymphatic vessels differ from the current, primarily mouse tissue–based textbook description. rupress.org/jem/article/...
#Lymphatics
#Lymphatics
Reposted by Ulvmar lab
‼️Lymphatic Education&Research Network-GRC Scholarships‼️
LE&RN is awarding 10 × $1,000 scholarships to early investigators to attend 2026 Lymphatics GRC March 1 – March 6, 2026, Lucca (Barga), Italy.
🗓 Apply by Dec 8, 2025!
form.jotform.com/LERN/2026-gr...
LE&RN is awarding 10 × $1,000 scholarships to early investigators to attend 2026 Lymphatics GRC March 1 – March 6, 2026, Lucca (Barga), Italy.
🗓 Apply by Dec 8, 2025!
form.jotform.com/LERN/2026-gr...
October 31, 2025 at 5:11 PM
‼️Lymphatic Education&Research Network-GRC Scholarships‼️
LE&RN is awarding 10 × $1,000 scholarships to early investigators to attend 2026 Lymphatics GRC March 1 – March 6, 2026, Lucca (Barga), Italy.
🗓 Apply by Dec 8, 2025!
form.jotform.com/LERN/2026-gr...
LE&RN is awarding 10 × $1,000 scholarships to early investigators to attend 2026 Lymphatics GRC March 1 – March 6, 2026, Lucca (Barga), Italy.
🗓 Apply by Dec 8, 2025!
form.jotform.com/LERN/2026-gr...