David Tobin
@tobinlab.bsky.social
Scientist at Duke studying tuberculosis, host susceptibility to infection, and mycobacterial pathogenesis. Views are my own and do not represent those of my employer.
Reposted by David Tobin
For our #InfectiousDisease Special Issue we interviewed the marvelous @harmitmalik.bsky.social ! We discussed the #viral arms race, how to support mentees and the beauty of basic science 🔬
journals.biologists.com/dmm/article/...
journals.biologists.com/dmm/article/...
The viral arms race: an interview with Harmit Malik
Harmit Malik. Photo credit: Fred Hutchinson Cancer Research Center.Harmit Malik is Professor and Associate Director of the Basic Sciences Division at the Fred Hutchinson Cancer Center in Seattle, WA,…
journals.biologists.com
November 10, 2025 at 2:05 PM
For our #InfectiousDisease Special Issue we interviewed the marvelous @harmitmalik.bsky.social ! We discussed the #viral arms race, how to support mentees and the beauty of basic science 🔬
journals.biologists.com/dmm/article/...
journals.biologists.com/dmm/article/...
Reposted by David Tobin
🔬 Applications are now open!
Join MBL’s world-renowned Advanced Research Training Courses, where scientists from around the globe come together to explore new ideas, master cutting-edge techniques, and become part of a dynamic network.
➡️Apply today: go.mbl.edu/courses
Join MBL’s world-renowned Advanced Research Training Courses, where scientists from around the globe come together to explore new ideas, master cutting-edge techniques, and become part of a dynamic network.
➡️Apply today: go.mbl.edu/courses
Course Offerings | Marine Biological Laboratory
go.mbl.edu
October 28, 2025 at 6:08 PM
🔬 Applications are now open!
Join MBL’s world-renowned Advanced Research Training Courses, where scientists from around the globe come together to explore new ideas, master cutting-edge techniques, and become part of a dynamic network.
➡️Apply today: go.mbl.edu/courses
Join MBL’s world-renowned Advanced Research Training Courses, where scientists from around the globe come together to explore new ideas, master cutting-edge techniques, and become part of a dynamic network.
➡️Apply today: go.mbl.edu/courses
Reposted by David Tobin
Part 6: For decades, the zebrafish has helped scientists unlock the mysteries of genetics, development, & disease. But the fish that power most discoveries have spent generations inside lab tanks. This video captures footage of zebrafish in their natural environment in Nepal.
youtu.be/cCZhZpPALqw
youtu.be/cCZhZpPALqw
Zebrafish in the wild
YouTube video by John Rawls
youtu.be
October 28, 2025 at 2:09 PM
Part 6: For decades, the zebrafish has helped scientists unlock the mysteries of genetics, development, & disease. But the fish that power most discoveries have spent generations inside lab tanks. This video captures footage of zebrafish in their natural environment in Nepal.
youtu.be/cCZhZpPALqw
youtu.be/cCZhZpPALqw
Reposted by David Tobin
Fantastic opportunity at The Hospital for Sick Children. Please repost. www.nature.com/naturecareer...
SCIENTIST – Developmental, Stem Cell & Cancer Biology Program - Toronto (City), Ontario (CA) job with The Hospital for Sick Children - Developmental & Stem Cell Biology Program | 12848200
Discovery-based and/or translational research using model organism genetics and/or stem cell and organoid platforms to study paediatric cancer.
www.nature.com
October 28, 2025 at 10:06 PM
Fantastic opportunity at The Hospital for Sick Children. Please repost. www.nature.com/naturecareer...
Reposted by David Tobin
Please repost!!:
We are searching for new AI-Bio faculty at Duke to be part of a new Discovery AI center. Looking for faculty who focus on pushing boundaries in ML model development in a highly interactive environment. DEADLINE for applications- Nov 1st!!
www.nature.com/naturecareer...
We are searching for new AI-Bio faculty at Duke to be part of a new Discovery AI center. Looking for faculty who focus on pushing boundaries in ML model development in a highly interactive environment. DEADLINE for applications- Nov 1st!!
www.nature.com/naturecareer...
Tenure-Track Assistant Professor Position –AI/ML for Cell Biology - Durham, North Carolina (US) job with Duke University School of Medicine | 12844591
Tenure-Track Assistant Professor Position –AI/ML for Cell Biology
www.nature.com
October 25, 2025 at 3:11 PM
Please repost!!:
We are searching for new AI-Bio faculty at Duke to be part of a new Discovery AI center. Looking for faculty who focus on pushing boundaries in ML model development in a highly interactive environment. DEADLINE for applications- Nov 1st!!
www.nature.com/naturecareer...
We are searching for new AI-Bio faculty at Duke to be part of a new Discovery AI center. Looking for faculty who focus on pushing boundaries in ML model development in a highly interactive environment. DEADLINE for applications- Nov 1st!!
www.nature.com/naturecareer...
Reposted by David Tobin
Part 1: The last couple of weeks I've had the pleasure of working with a team of scientists from Duke University, University of Oregon, and Agriculture and Forestry University (AFU) in Nepal to study the biology of zebrafish in their natural habitat. ...
October 22, 2025 at 9:20 AM
Part 1: The last couple of weeks I've had the pleasure of working with a team of scientists from Duke University, University of Oregon, and Agriculture and Forestry University (AFU) in Nepal to study the biology of zebrafish in their natural habitat. ...
Reposted by David Tobin
In this issue:
· Interview with @harmitmalik.bsky.social
· Interview with Zolelwa Sifumba
· Perspective on unravelling γδ T-cell dysregulation in the gut & its implications for immune-mediated diseases
· 'At a glance' on engineered bacteriophages
· Review on neuroinflammation in fungal infections
· Interview with @harmitmalik.bsky.social
· Interview with Zolelwa Sifumba
· Perspective on unravelling γδ T-cell dysregulation in the gut & its implications for immune-mediated diseases
· 'At a glance' on engineered bacteriophages
· Review on neuroinflammation in fungal infections
October 21, 2025 at 1:14 PM
In this issue:
· Interview with @harmitmalik.bsky.social
· Interview with Zolelwa Sifumba
· Perspective on unravelling γδ T-cell dysregulation in the gut & its implications for immune-mediated diseases
· 'At a glance' on engineered bacteriophages
· Review on neuroinflammation in fungal infections
· Interview with @harmitmalik.bsky.social
· Interview with Zolelwa Sifumba
· Perspective on unravelling γδ T-cell dysregulation in the gut & its implications for immune-mediated diseases
· 'At a glance' on engineered bacteriophages
· Review on neuroinflammation in fungal infections
Reposted by David Tobin
New preprint up with collaborators Jianguo Lu, @mpodobnik.bsky.social, Uwe Irion, Braedan McCluskey, John Postlethwait and others. New Danio genomes, evolution and pigment pattern variation. Long time in the making www.biorxiv.org/content/10.1...
October 19, 2025 at 10:28 PM
New preprint up with collaborators Jianguo Lu, @mpodobnik.bsky.social, Uwe Irion, Braedan McCluskey, John Postlethwait and others. New Danio genomes, evolution and pigment pattern variation. Long time in the making www.biorxiv.org/content/10.1...
Congratulations to grad student extraordinaire Kirsten Smith @kms99.bsky.social and all the other awardees @bwfund.bsky.social www.bwfund.org/news/bwf-exp...
BWF Expands Graduate Diversity Enrichment Program to Support 14 Pre-Doctoral Scholars - Burroughs Wellcome Fund
DURHAM, N.C. – The Burroughs Wellcome Fund (BWF) is proud to announce the 2025 recipients of the Graduate Diversity Enrichment Program (GDEP)—fourteen outstanding pre-doctoral scientists whose work re...
www.bwfund.org
October 17, 2025 at 7:19 PM
Congratulations to grad student extraordinaire Kirsten Smith @kms99.bsky.social and all the other awardees @bwfund.bsky.social www.bwfund.org/news/bwf-exp...
Reposted by David Tobin
Despite the mess, we are grateful to be funded, have exciting science happening, and have an opening for a postdoc!
If you are interested in sensory biology and esp in cilia, thermosensation, or interoception, and would like to join an interactive & supportive group - please email.
Please RT 🙏
If you are interested in sensory biology and esp in cilia, thermosensation, or interoception, and would like to join an interactive & supportive group - please email.
Please RT 🙏
October 16, 2025 at 5:29 PM
Despite the mess, we are grateful to be funded, have exciting science happening, and have an opening for a postdoc!
If you are interested in sensory biology and esp in cilia, thermosensation, or interoception, and would like to join an interactive & supportive group - please email.
Please RT 🙏
If you are interested in sensory biology and esp in cilia, thermosensation, or interoception, and would like to join an interactive & supportive group - please email.
Please RT 🙏
Reposted by David Tobin
🚨Job posting! #UMassAmherst Department of Veterinary and Animal Sciences is hiring a TT faculty member in #Immunology. Both fundamental and translational areas considered. Please spread the word!
careers.umass.edu/amherst/en-u...
careers.umass.edu/amherst/en-u...
Details - Assistant Professor - Immunology | Human Resources | UMass Amherst
careers.umass.edu
October 15, 2025 at 9:07 PM
🚨Job posting! #UMassAmherst Department of Veterinary and Animal Sciences is hiring a TT faculty member in #Immunology. Both fundamental and translational areas considered. Please spread the word!
careers.umass.edu/amherst/en-u...
careers.umass.edu/amherst/en-u...
Reposted by David Tobin
“The White House’s mass firing of Centers for Disease Control and Prevention staff on Friday has decimated offices related to injury prevention, respiratory disease surveillance, and chronic disease.” www.statnews.com/2025/10/11/c...
‘It’s a massacre’: CDC battered by government shutdown firings
The White House’s mass firing of CDC staff on Friday has decimated offices related to injury prevention, respiratory disease surveillance, and chronic disease, according to four people familiar with t...
www.statnews.com
October 11, 2025 at 7:58 PM
“The White House’s mass firing of Centers for Disease Control and Prevention staff on Friday has decimated offices related to injury prevention, respiratory disease surveillance, and chronic disease.” www.statnews.com/2025/10/11/c...
Reposted by David Tobin
RIFs at CDC.
Destroying the Epidemic Intelligence Service, NCIRD, NCIPC & a dozen other areas/divisions/branches will cause enormous harm and suffering to America, and indeed to the whole world.
Call your Reps about it.
Then call them again.
Destroying the Epidemic Intelligence Service, NCIRD, NCIPC & a dozen other areas/divisions/branches will cause enormous harm and suffering to America, and indeed to the whole world.
Call your Reps about it.
Then call them again.
October 11, 2025 at 4:09 PM
RIFs at CDC.
Destroying the Epidemic Intelligence Service, NCIRD, NCIPC & a dozen other areas/divisions/branches will cause enormous harm and suffering to America, and indeed to the whole world.
Call your Reps about it.
Then call them again.
Destroying the Epidemic Intelligence Service, NCIRD, NCIPC & a dozen other areas/divisions/branches will cause enormous harm and suffering to America, and indeed to the whole world.
Call your Reps about it.
Then call them again.
Reposted by David Tobin
Wonderful collaboration of Claire Arata and co-first-author Elena Vasileva from Amatruda lab. Claire provided the neural crest driver and Elena the EWS oncofusion. Best combination since PB&J. Amazing that expression of a single oncofusion in crest produces ectopic fins.
www.cell.com/cell-reports...
www.cell.com/cell-reports...
Origin of Ewing sarcoma by embryonic reprogramming of neural crest to mesoderm
Using a zebrafish genetic model of Ewing sarcoma, Vasileva et al. provide evidence
for a neural crest origin of the disease. These findings offer new insight into how
a single oncogenic fusion can hij...
www.cell.com
October 10, 2025 at 12:31 AM
Wonderful collaboration of Claire Arata and co-first-author Elena Vasileva from Amatruda lab. Claire provided the neural crest driver and Elena the EWS oncofusion. Best combination since PB&J. Amazing that expression of a single oncofusion in crest produces ectopic fins.
www.cell.com/cell-reports...
www.cell.com/cell-reports...
Reposted by David Tobin
We are inviting applications for postdoctoral fellows in immunology of TB at the South African Tuberculosis Vaccine Initiative, University of Cape Town. For more information see the attached ad:
idm.uct.ac.za/media/739223
idm.uct.ac.za/media/739223
October 9, 2025 at 11:28 AM
We are inviting applications for postdoctoral fellows in immunology of TB at the South African Tuberculosis Vaccine Initiative, University of Cape Town. For more information see the attached ad:
idm.uct.ac.za/media/739223
idm.uct.ac.za/media/739223
Reposted by David Tobin
We're hiring! Check out our ad and please re-post or forward to interested #Microbiology parties: apply.interfolio.com/174783
Apply - Interfolio
{{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
October 7, 2025 at 4:10 PM
We're hiring! Check out our ad and please re-post or forward to interested #Microbiology parties: apply.interfolio.com/174783
Reposted by David Tobin
UChicago Microbiology is searching for tenured or tenure-track faculty working in host-pathogens interactions, viral and bacterial pathogenesis, and emerging infectious diseases. Come join our vibrant Department! microbiology.uchicago.edu
Apply here apply.interfolio.com/174404
Apply here apply.interfolio.com/174404
Department of Microbiology | The University of Chicago
microbiology.uchicago.edu
October 6, 2025 at 5:32 PM
UChicago Microbiology is searching for tenured or tenure-track faculty working in host-pathogens interactions, viral and bacterial pathogenesis, and emerging infectious diseases. Come join our vibrant Department! microbiology.uchicago.edu
Apply here apply.interfolio.com/174404
Apply here apply.interfolio.com/174404
Important piece from Sarah Stanley at Berkeley on new NIH definitions that can be construed to arbitrarily halt research that is both safe and important to public health and future cures www.statnews.com/2025/10/06/g... via @statnews.com
The NIH ordered me to stop my ‘dangerous’ gain-of-function research. It isn’t dangerous at all
Safe gain-of-function research is necessary to identify new treatments for diseases like for tuberculosis — but the NIH has imposed unfounded stops.
www.statnews.com
October 6, 2025 at 12:15 PM
Important piece from Sarah Stanley at Berkeley on new NIH definitions that can be construed to arbitrarily halt research that is both safe and important to public health and future cures www.statnews.com/2025/10/06/g... via @statnews.com
Reposted by David Tobin
Now online! Evolution of Mycobacterium tuberculosis transcription regulation is associated with increased transmission and drug resistance
Evolution of Mycobacterium tuberculosis transcription regulation is associated with increased transmission and drug resistance
Mycobacterium tuberculosis isolates have a complex phylogenetic structure and vary in clinical phenotypes. Combining high-throughput RNA-seq and global population genomics reveals gene expression as an axis of variation in host interaction. Underscoring this, variants in a regulator of a key virulence pathway are associated with increased transmission and drug resistance.
dlvr.it
September 30, 2025 at 6:51 PM
Now online! Evolution of Mycobacterium tuberculosis transcription regulation is associated with increased transmission and drug resistance
Reposted by David Tobin
NSF today released instructions for the next round of applicants to its Graduate Research Fellowship Program. A key group—second-year Ph.D. students—is no longer eligible, and students who are still able to apply will face an unusually narrow timeframe. https://scim.ag/3KlQkQk
‘Completely shattered.’ Changes to NSF’s graduate student fellowship spur outcry
The announcement comes months later than usual, leaving many would-be applicants stranded
www.science.org
September 26, 2025 at 11:09 PM
NSF today released instructions for the next round of applicants to its Graduate Research Fellowship Program. A key group—second-year Ph.D. students—is no longer eligible, and students who are still able to apply will face an unusually narrow timeframe. https://scim.ag/3KlQkQk
Reposted by David Tobin
Eric Peterman @errricpeterman.bsky.social, Jeffrey Rasmussen @jraslab.bsky.social @uwbiology.bsky.social & colleagues discover that microtubules regulate tissue-level navigation in skin-resident macrophages.
journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...
September 24, 2025 at 8:13 AM
Eric Peterman @errricpeterman.bsky.social, Jeffrey Rasmussen @jraslab.bsky.social @uwbiology.bsky.social & colleagues discover that microtubules regulate tissue-level navigation in skin-resident macrophages.
journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...
Reposted by David Tobin
Abstract submissions are open for the Midwinter Conference of Immunologists @midwinter-immun.bsky.social!! www.midwconfimmunol.org The Early Bird Registration deadline is Nov 14, 2025.
There will be lots of Selected Abstract talks so submit an abstract to be considered!
There will be lots of Selected Abstract talks so submit an abstract to be considered!
Midwinter Conference of Immunologists
The Midwinter Conference of Immunologists was founded in 1961 by a small group of Immunologists, among them Drs. Dan Campbell and Ray Owen. The goal of the Midwinter Conference is to provide a forum w...
www.midwconfimmunol.org
September 22, 2025 at 1:12 PM
Abstract submissions are open for the Midwinter Conference of Immunologists @midwinter-immun.bsky.social!! www.midwconfimmunol.org The Early Bird Registration deadline is Nov 14, 2025.
There will be lots of Selected Abstract talks so submit an abstract to be considered!
There will be lots of Selected Abstract talks so submit an abstract to be considered!
Reposted by David Tobin
Today, scientists know that genetics plays a role in many conditions and diseases. But back in the ’90s, geneticist Mary-Claire King was the first to link a gene to an inherited form of a common cancer.
A Trailblazing Geneticist Reflects On Her Life And Work
Dr. Mary-Claire King was the first to link a gene to hereditary cancer risk with the identification of BRCA1. She was just getting started.
buff.ly
September 19, 2025 at 6:12 PM
Today, scientists know that genetics plays a role in many conditions and diseases. But back in the ’90s, geneticist Mary-Claire King was the first to link a gene to an inherited form of a common cancer.
Reposted by David Tobin
Immigrants, particularly on H1Bs, are the lifeblood of American innovation. If you wanted to hurt US competitiveness in the next century, I can think of few more effective ways than a move like this
Even when found illegal, the mere intent will have irreparably harmed our future
Even when found illegal, the mere intent will have irreparably harmed our future
September 20, 2025 at 4:24 PM
Immigrants, particularly on H1Bs, are the lifeblood of American innovation. If you wanted to hurt US competitiveness in the next century, I can think of few more effective ways than a move like this
Even when found illegal, the mere intent will have irreparably harmed our future
Even when found illegal, the mere intent will have irreparably harmed our future
Reposted by David Tobin
Yup. This was me 10 years ago.
Why is this horrible for Universities?
Just about everyone who isn't a citizen or green card holder already who's hired for a tenure track faculty position is hired through an H1B and then, after 3-5 years, applies for a green card.
This is literally "No more foreign professors can be hired"
Just about everyone who isn't a citizen or green card holder already who's hired for a tenure track faculty position is hired through an H1B and then, after 3-5 years, applies for a green card.
This is literally "No more foreign professors can be hired"
Those on an H1B cannot return to the US from tomorrow (Sunday) unless paying $100K. This is an out-of-the blue presidential action. We’ll see software engineers stranded abroad.
One easy to predict outcome: those on US visas will travel less… for work, for conferences etc.
One easy to predict outcome: those on US visas will travel less… for work, for conferences etc.
September 20, 2025 at 4:03 PM
Yup. This was me 10 years ago.