Tilmann Schober
@tilmannschober.bsky.social
Pediatrics, Infectious Diseases & Medical Microbiology, Husband & Father, Hiker & Cyclist, Reader & Gardener
Currently in Munich, previously in Montreal
Currently in Munich, previously in Montreal
Reposted by Tilmann Schober
Community-acquired respiratory virus infections in patients with haematological malignancies or undergoing haematopoietic cell transplantation: updated recommendations from the 10th European Conference on Infections in Leukaemia
www.thelancet.com/journals/lan... 🔓 #TxID
www.thelancet.com/journals/lan... 🔓 #TxID
Community-acquired respiratory virus infections in patients with haematological malignancies or undergoing haematopoietic cell transplantation: updated recommendations from the 10th European Conferenc...
To update recommendations of the 4th European Conference on Infections in Leukaemia
(ECIL-4) on community-acquired respiratory virus (CARV) infections published in 2013,
we reviewed publications from ...
www.thelancet.com
August 28, 2025 at 12:09 PM
Community-acquired respiratory virus infections in patients with haematological malignancies or undergoing haematopoietic cell transplantation: updated recommendations from the 10th European Conference on Infections in Leukaemia
www.thelancet.com/journals/lan... 🔓 #TxID
www.thelancet.com/journals/lan... 🔓 #TxID
Feeling like the world is spinning out of control? 🌍 There’s plenty to worry about…
BUT: even in the last 5 years, global poverty has continued to decline. 📉✨
Progress is possible—and it’s happening.
BUT: even in the last 5 years, global poverty has continued to decline. 📉✨
Progress is possible—and it’s happening.
To track progress towards ending extreme poverty by 2030, the United Nations relies on the World Bank to estimate the share of people living below a certain threshold, called the International Poverty Line (IPL).
August 28, 2025 at 3:26 PM
Feeling like the world is spinning out of control? 🌍 There’s plenty to worry about…
BUT: even in the last 5 years, global poverty has continued to decline. 📉✨
Progress is possible—and it’s happening.
BUT: even in the last 5 years, global poverty has continued to decline. 📉✨
Progress is possible—and it’s happening.
Real world effectiveness of maternal RSV vaccination looks pretty awesome: 77% against RSV-associated severe LRTD leading to hospitalisation from birth to age 6 https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00156-2/abstract
August 21, 2025 at 7:34 PM
Real world effectiveness of maternal RSV vaccination looks pretty awesome: 77% against RSV-associated severe LRTD leading to hospitalisation from birth to age 6 https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00156-2/abstract
Reposted by Tilmann Schober
A clinical practice guideline for tuberculous meningitis
Tuberculous Meningitis International Research Consortium
www.thelancet.com/journals/lan... 🔒
Tuberculous Meningitis International Research Consortium
www.thelancet.com/journals/lan... 🔒
A clinical practice guideline for tuberculous meningitis
Tuberculous meningitis is the most severe form of tuberculosis, causing death or disability
in around half of those affected. There are no up-to-date international guidelines
defining its optimal mana...
www.thelancet.com
August 19, 2025 at 1:15 PM
A clinical practice guideline for tuberculous meningitis
Tuberculous Meningitis International Research Consortium
www.thelancet.com/journals/lan... 🔒
Tuberculous Meningitis International Research Consortium
www.thelancet.com/journals/lan... 🔒
Measles cases in Canada. Don’t know what to say…
https://health-infobase.canada.ca/measles-rubella/
https://health-infobase.canada.ca/measles-rubella/
August 8, 2025 at 5:22 AM
Measles cases in Canada. Don’t know what to say…
https://health-infobase.canada.ca/measles-rubella/
https://health-infobase.canada.ca/measles-rubella/
How some well-known universities are trying to sabotage the tenure system...
Research for grants rather than grants for research.
This kind of policy, especially with additional cuts to federal funding, will create perverse incentives that will have consequences on the actual science that this whole system is supposed to support.
www.dukechronicle.com/article/2025...
This kind of policy, especially with additional cuts to federal funding, will create perverse incentives that will have consequences on the actual science that this whole system is supposed to support.
www.dukechronicle.com/article/2025...
Duke School of Medicine plans salary cuts for tenured faculty who do not meet grant expectations
Set to go in effect in 2026, the proposed policy would apply to the School’s basic sciences units. These units rely heavily on grants from the National Institutes of Health, which have been increasing...
www.dukechronicle.com
July 21, 2025 at 10:19 PM
How some well-known universities are trying to sabotage the tenure system...
Fascinating example of the link between ecosystem stability and human well-being 👇🏻
Large scavengers like vultures and hyenas do an important job in protecting human health. But studies show these creatures are on the decline, allowing for the emergence of disease.
Next time you see a vulture picking over a carcass, say 'thank you!'
Large scavengers like vultures and hyenas do an important job in protecting human health. But studies show these creatures are on the decline, allowing for the emergence of disease.
n.pr
July 11, 2025 at 6:12 PM
Fascinating example of the link between ecosystem stability and human well-being 👇🏻
Reposted by Tilmann Schober
Tick-borne encephalitis (TBE) in Europe: new maps published www.ecdc.europa.eu/en/news-even...
Tick-borne encephalitis (TBE) in Europe: new maps published
New maps published by ECDC show that hotspots for tick-borne encephalitis (TBE) in the EU are mainly concentrated in Central, Eastern, and Northern Europe, based on 2023 notification rates of locally-...
www.ecdc.europa.eu
June 27, 2025 at 3:10 PM
Tick-borne encephalitis (TBE) in Europe: new maps published www.ecdc.europa.eu/en/news-even...
Reposted by Tilmann Schober
Reposted by Tilmann Schober
This is a scary article by Carl Zimmer about the how scientists have found a second species of the fungus that causes white nose syndrome in bats. A potentially devastating development 🧪🦇
A Fungus Devastated North American Bats. A New Species Could Deliver a Killer Blow.
www.nytimes.com
May 30, 2025 at 2:09 AM
This is a scary article by Carl Zimmer about the how scientists have found a second species of the fungus that causes white nose syndrome in bats. A potentially devastating development 🧪🦇
To express it in a consciously neutral way:
Most (if not all) 🇪🇺 countries stopped vaccinating healthy children against SARS-CoV-2
BUT
all 🇪🇺 countries recommend these vaccines for pregnant women!
Quite incomprehensible from an international perspective. I feel sorry for our colleagues in the US.
Most (if not all) 🇪🇺 countries stopped vaccinating healthy children against SARS-CoV-2
BUT
all 🇪🇺 countries recommend these vaccines for pregnant women!
Quite incomprehensible from an international perspective. I feel sorry for our colleagues in the US.
Breaking news: Health and Human Services Secretary Robert F. Kennedy Jr. is ending his agency's recommendation that healthy pregnant women and healthy children receive the coronavirus vaccine.
RFK Jr. ends covid shot recommendation for healthy children, pregnant women
Currently the vaccine is recommended for all people over 6 months of age.
www.washingtonpost.com
May 27, 2025 at 5:47 PM
To express it in a consciously neutral way:
Most (if not all) 🇪🇺 countries stopped vaccinating healthy children against SARS-CoV-2
BUT
all 🇪🇺 countries recommend these vaccines for pregnant women!
Quite incomprehensible from an international perspective. I feel sorry for our colleagues in the US.
Most (if not all) 🇪🇺 countries stopped vaccinating healthy children against SARS-CoV-2
BUT
all 🇪🇺 countries recommend these vaccines for pregnant women!
Quite incomprehensible from an international perspective. I feel sorry for our colleagues in the US.
Reposted by Tilmann Schober
Azithromycin can no longer be used for acne, stomach ulcers, or asthma prevention per EMA’s new recommendation. A key move against #antimicrobialresistance.
Details 👉 www.ema.europa.eu/en/news/chan...
Details 👉 www.ema.europa.eu/en/news/chan...
May 26, 2025 at 1:16 PM
Azithromycin can no longer be used for acne, stomach ulcers, or asthma prevention per EMA’s new recommendation. A key move against #antimicrobialresistance.
Details 👉 www.ema.europa.eu/en/news/chan...
Details 👉 www.ema.europa.eu/en/news/chan...
Disastrous, but unfortunately not surprising given the attitude of the current US leadership towards mRNA vaccines…
Moderna withdraws application for U.S. approval of combined flu-Covid shot. After talks with Food and Drug Administration, company plans to resubmit vaccine application later this year. www.theguardian.com/us-news/2025... via @theguardian.com #influenza #COVID19
Moderna withdraws application for US approval of combined flu-Covid shot
After talks with Food and Drug Administration, company plans to resubmit vaccine application later this year
www.theguardian.com
May 21, 2025 at 6:28 PM
Disastrous, but unfortunately not surprising given the attitude of the current US leadership towards mRNA vaccines…
Reposted by Tilmann Schober
Words matter.
It’s time to retire the term oral “step-down.”
It implies inferiority of the oral route—and doesn’t align with stewardship principles.
Terms like IV to oral switch or oral transition better promote optimal antimicrobial stewardship.
What terms do you use—and why? #idsky
It’s time to retire the term oral “step-down.”
It implies inferiority of the oral route—and doesn’t align with stewardship principles.
Terms like IV to oral switch or oral transition better promote optimal antimicrobial stewardship.
What terms do you use—and why? #idsky
May 21, 2025 at 2:48 PM
Words matter.
It’s time to retire the term oral “step-down.”
It implies inferiority of the oral route—and doesn’t align with stewardship principles.
Terms like IV to oral switch or oral transition better promote optimal antimicrobial stewardship.
What terms do you use—and why? #idsky
It’s time to retire the term oral “step-down.”
It implies inferiority of the oral route—and doesn’t align with stewardship principles.
Terms like IV to oral switch or oral transition better promote optimal antimicrobial stewardship.
What terms do you use—and why? #idsky
Reposted by Tilmann Schober
“children vaccinated before 8.5 months of age exhibited a markedly faster antibody decay and lost their protective neutralizing antibody levels over 6 years.”
So, in times of outbreaks, when infants get an early💉dose to get protection ASAP, they’ll likely still need their 2 scheduled doses later
So, in times of outbreaks, when infants get an early💉dose to get protection ASAP, they’ll likely still need their 2 scheduled doses later
Long-term Dynamics of Measles Virus–Specific Neutralizing Antibodies in Children Vaccinated Before 12 Months of Age
⭐ Editor's Choice
⭐ Editor's Choice
Long-term Dynamics of Measles Virus–Specific Neutralizing Antibodies in Children Vaccinated Before 12 Months of Age
Measles is a highly contagious disease, presenting a significant risk for unvaccinated infants and adults. Measles vaccination under the age of 12 months provides early protection but has also been associated with blunting of antibody responses to subsequent measles vaccinations and assumed to have lower vaccine effectiveness.
academic.oup.com
May 18, 2025 at 7:04 PM
“children vaccinated before 8.5 months of age exhibited a markedly faster antibody decay and lost their protective neutralizing antibody levels over 6 years.”
So, in times of outbreaks, when infants get an early💉dose to get protection ASAP, they’ll likely still need their 2 scheduled doses later
So, in times of outbreaks, when infants get an early💉dose to get protection ASAP, they’ll likely still need their 2 scheduled doses later
Reposted by Tilmann Schober
This is such an important shift. For many years the catholic church withheld support for HPV vaccination which prevents cervical cancer.
119,000 women die from this cancer in Africa every year.
This full throated support of the HPV vaxx by the church will help uptake.
nation.africa/kenya/health...
119,000 women die from this cancer in Africa every year.
This full throated support of the HPV vaxx by the church will help uptake.
nation.africa/kenya/health...
We can't remain indifferent to suffering: Catholic Church now champions HPV vaccination
From opposition to advocacy: After dismissing vaccine over promiscuity fears, church now tells faithful early intervention saves lives
nation.africa
May 16, 2025 at 9:14 PM
This is such an important shift. For many years the catholic church withheld support for HPV vaccination which prevents cervical cancer.
119,000 women die from this cancer in Africa every year.
This full throated support of the HPV vaxx by the church will help uptake.
nation.africa/kenya/health...
119,000 women die from this cancer in Africa every year.
This full throated support of the HPV vaxx by the church will help uptake.
nation.africa/kenya/health...
It's been a long journey...but I finally got my board certification for Microbiology, Virology and Infection Epidemiology!
What a fun ride - thanks to all my great mentors at @healthsciences.mcgill.ca 🇨🇦 & @lmumuenchen.bsky.social 🇩🇪!
What a fun ride - thanks to all my great mentors at @healthsciences.mcgill.ca 🇨🇦 & @lmumuenchen.bsky.social 🇩🇪!
May 16, 2025 at 9:43 PM
It's been a long journey...but I finally got my board certification for Microbiology, Virology and Infection Epidemiology!
What a fun ride - thanks to all my great mentors at @healthsciences.mcgill.ca 🇨🇦 & @lmumuenchen.bsky.social 🇩🇪!
What a fun ride - thanks to all my great mentors at @healthsciences.mcgill.ca 🇨🇦 & @lmumuenchen.bsky.social 🇩🇪!
Second case of Subacute Sclerosing Panencephalitis in a few weeks. Hard to bear…
May 16, 2025 at 5:25 PM
Second case of Subacute Sclerosing Panencephalitis in a few weeks. Hard to bear…
Reposted by Tilmann Schober
New Canadian #flu paper @stephaniedavey.bsky.social
"It is notable that over 1/4 of deaths occurred in children without a medical condition deemed high risk for #influenza complications, highlighting importance of preventative measures for all children."
#vaccines #vaccineswork #publichealth 🧪
"It is notable that over 1/4 of deaths occurred in children without a medical condition deemed high risk for #influenza complications, highlighting importance of preventative measures for all children."
#vaccines #vaccineswork #publichealth 🧪
Which kids are at risk of severe influenza? Our work on pediatric influenza associated mortality was just published - it was an honor to contribute. 👇 www.jpeds.com/article/S002...
Not surprisingly, we conclude "Vaccination efforts should be enhanced to reduce influenza mortality."
Not surprisingly, we conclude "Vaccination efforts should be enhanced to reduce influenza mortality."
Influenza-Associated Mortality Among Children in Canada from 2004 to 2022
We identified 80 pediatric influenza-associated deaths in Canadian pediatric tertiary
hospitals from 2004 to 2022. Children aged <5 years and with high-risk conditions
represented 55% and 77.5% of cas...
www.jpeds.com
May 11, 2025 at 9:12 AM
New Canadian #flu paper @stephaniedavey.bsky.social
"It is notable that over 1/4 of deaths occurred in children without a medical condition deemed high risk for #influenza complications, highlighting importance of preventative measures for all children."
#vaccines #vaccineswork #publichealth 🧪
"It is notable that over 1/4 of deaths occurred in children without a medical condition deemed high risk for #influenza complications, highlighting importance of preventative measures for all children."
#vaccines #vaccineswork #publichealth 🧪
Reposted by Tilmann Schober
She could be the next US Surgeon General?
“The future of medicine will be about light. I don’t exactly know how.”
www.motherjones.com/politics/202...
“The future of medicine will be about light. I don’t exactly know how.”
www.motherjones.com/politics/202...
Trump’s new surgeon general pick wants to “raise the vibration of humanity”
“The future of medicine will be about light," said Casey Means. "I don’t exactly know how.”
www.motherjones.com
May 9, 2025 at 9:29 PM
She could be the next US Surgeon General?
“The future of medicine will be about light. I don’t exactly know how.”
www.motherjones.com/politics/202...
“The future of medicine will be about light. I don’t exactly know how.”
www.motherjones.com/politics/202...
Reposted by Tilmann Schober
Are we ever going to get RCTs to test whether metagenomics improves clinical outcomes, or will it remain a whole load of 'evaluations' that are really just clinical services? What would a trial look like? Tricky given the technology is advancing quickly
#IDSky #MicroSky @drmichaelmarks.bsky.social
#IDSky #MicroSky @drmichaelmarks.bsky.social
Great paper by @target-amr.bsky.social leadership team colleagues @drtessjohnson.bsky.social and Steph Johnson on the ethics of clinical metagenomics
www.microbiologyresearch.org/content/jour...
www.microbiologyresearch.org/content/jour...
Clinical metagenomics: ethical issues
Metagenomics is increasingly used for diagnosis in hospital settings. It is useful particularly in cases of unknown aetiology, where novel or difficult-to-diagnose pathogens are suspected, and/or foll...
www.microbiologyresearch.org
May 10, 2025 at 7:39 PM
Are we ever going to get RCTs to test whether metagenomics improves clinical outcomes, or will it remain a whole load of 'evaluations' that are really just clinical services? What would a trial look like? Tricky given the technology is advancing quickly
#IDSky #MicroSky @drmichaelmarks.bsky.social
#IDSky #MicroSky @drmichaelmarks.bsky.social
Which kids are at risk of severe influenza? Our work on pediatric influenza associated mortality was just published - it was an honor to contribute. 👇 www.jpeds.com/article/S002...
Not surprisingly, we conclude "Vaccination efforts should be enhanced to reduce influenza mortality."
Not surprisingly, we conclude "Vaccination efforts should be enhanced to reduce influenza mortality."
Influenza-Associated Mortality Among Children in Canada from 2004 to 2022
We identified 80 pediatric influenza-associated deaths in Canadian pediatric tertiary
hospitals from 2004 to 2022. Children aged <5 years and with high-risk conditions
represented 55% and 77.5% of cas...
www.jpeds.com
May 10, 2025 at 8:21 PM
Which kids are at risk of severe influenza? Our work on pediatric influenza associated mortality was just published - it was an honor to contribute. 👇 www.jpeds.com/article/S002...
Not surprisingly, we conclude "Vaccination efforts should be enhanced to reduce influenza mortality."
Not surprisingly, we conclude "Vaccination efforts should be enhanced to reduce influenza mortality."
Just did a consult on a toddler who developed a terrible hemolytic uraemic syndrome after drinking raw milk.
It’s real, don’t do it
It’s real, don’t do it
a boy with his eyes closed and the words bad idea written below him
ALT: a boy with his eyes closed and the words bad idea written below him
media.tenor.com
May 10, 2025 at 8:30 AM
Just did a consult on a toddler who developed a terrible hemolytic uraemic syndrome after drinking raw milk.
It’s real, don’t do it
It’s real, don’t do it
Reposted by Tilmann Schober
New hope for LYME DISEASE, right under our eyes?
Unbiased screen surprisingly shows PIPERACILLIN can wipe out 𝘉𝘰𝘳𝘳𝘦𝘭𝘪𝘢 𝘣𝘶𝘳𝘨𝘥𝘰𝘳𝘧𝘦𝘳𝘪 in mice at tiny doses — 100 times lower than doxycycline — while leaving gut bacteria intact
Jutras Lab Northwestern Sci Transl Med
www.science.org/doi/10.1126/...
Unbiased screen surprisingly shows PIPERACILLIN can wipe out 𝘉𝘰𝘳𝘳𝘦𝘭𝘪𝘢 𝘣𝘶𝘳𝘨𝘥𝘰𝘳𝘧𝘦𝘳𝘪 in mice at tiny doses — 100 times lower than doxycycline — while leaving gut bacteria intact
Jutras Lab Northwestern Sci Transl Med
www.science.org/doi/10.1126/...
April 26, 2025 at 8:11 AM
New hope for LYME DISEASE, right under our eyes?
Unbiased screen surprisingly shows PIPERACILLIN can wipe out 𝘉𝘰𝘳𝘳𝘦𝘭𝘪𝘢 𝘣𝘶𝘳𝘨𝘥𝘰𝘳𝘧𝘦𝘳𝘪 in mice at tiny doses — 100 times lower than doxycycline — while leaving gut bacteria intact
Jutras Lab Northwestern Sci Transl Med
www.science.org/doi/10.1126/...
Unbiased screen surprisingly shows PIPERACILLIN can wipe out 𝘉𝘰𝘳𝘳𝘦𝘭𝘪𝘢 𝘣𝘶𝘳𝘨𝘥𝘰𝘳𝘧𝘦𝘳𝘪 in mice at tiny doses — 100 times lower than doxycycline — while leaving gut bacteria intact
Jutras Lab Northwestern Sci Transl Med
www.science.org/doi/10.1126/...
Reposted by Tilmann Schober
👶🏼 Many #vaccines are not effective in newborns. So how do we protect them from infectious disease?
🤰🏽 By vaccination in #pregnancy!
Here we review…
💉 Established campaigns vs whooping cough, flu, COVID
💡 New approaches to RSV, GBS
🌈 Future challenges, opportunities
#ReproSky #ImmunoSky #IDSky
🤰🏽 By vaccination in #pregnancy!
Here we review…
💉 Established campaigns vs whooping cough, flu, COVID
💡 New approaches to RSV, GBS
🌈 Future challenges, opportunities
#ReproSky #ImmunoSky #IDSky
Vaccination in pregnancy to protect the newborn - Nature Reviews Immunology
In this Review, Male and Jones provide an overview of the current vaccines that are offered during pregnancy and to newborns, explaining the rationale behind the different vaccination programmes and t...
www.nature.com
April 24, 2025 at 6:21 AM
👶🏼 Many #vaccines are not effective in newborns. So how do we protect them from infectious disease?
🤰🏽 By vaccination in #pregnancy!
Here we review…
💉 Established campaigns vs whooping cough, flu, COVID
💡 New approaches to RSV, GBS
🌈 Future challenges, opportunities
#ReproSky #ImmunoSky #IDSky
🤰🏽 By vaccination in #pregnancy!
Here we review…
💉 Established campaigns vs whooping cough, flu, COVID
💡 New approaches to RSV, GBS
🌈 Future challenges, opportunities
#ReproSky #ImmunoSky #IDSky