Tom Yates
@tomayates.bsky.social
Epidemiology, infection
https://profiles.ucl.ac.uk/37299-tom-yates/about
https://profiles.ucl.ac.uk/37299-tom-yates/about
Pinned
Philosophical Transactions of the Royal Society B: Biological Sciences: Vol 380, No 1938
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NEW JOURNAL ISSUE!
The indirect effects of cytomegalovirus infection: mechanisms and consequences
Enjoyed editing this with Helen Payne and @strangviruslab.bsky.social
Includes protocol for NIRVANA trial, which is getting started in Uganda and South Africa
#idsky #virosky
The indirect effects of cytomegalovirus infection: mechanisms and consequences
Enjoyed editing this with Helen Payne and @strangviruslab.bsky.social
Includes protocol for NIRVANA trial, which is getting started in Uganda and South Africa
#idsky #virosky
The genius of Mamdani is that he advanced progressive positions within the major party of the left
I fear Polanski's impact will be more Stein than Mamdani
The people united, and all that
I fear Polanski's impact will be more Stein than Mamdani
The people united, and all that
What happens if the Greens overtake Labour in the polls? All bets are off | Gaby Hinsliff
What happens if the Greens overtake Labour in the polls? All bets are off | Gaby Hinsliff
They may lack Labour’s party machine, but Zack Polanski’s burgeoning popularity could have seismic consequences for British politics, says Guardian columnist Gaby Hinsliff
www.theguardian.com
November 11, 2025 at 8:14 AM
The genius of Mamdani is that he advanced progressive positions within the major party of the left
I fear Polanski's impact will be more Stein than Mamdani
The people united, and all that
I fear Polanski's impact will be more Stein than Mamdani
The people united, and all that
Reposted by Tom Yates
NEW PAPER!
Here is the intro to our theme issue, incl a summary of included papers and overview of key debates in the field
Increasing mechanistic understanding but little work robustly quantifying impact of CMV indirect effects on population health
We suggest a few ways forward!
#IDSky #ViroSky
Here is the intro to our theme issue, incl a summary of included papers and overview of key debates in the field
Increasing mechanistic understanding but little work robustly quantifying impact of CMV indirect effects on population health
We suggest a few ways forward!
#IDSky #ViroSky
The indirect effects of cytomegalovirus infection—mechanisms and consequences | Philosophical Transactions of the Royal Society B: Biological Sciences
In this introduction, we summarize the research papers, review articles, opinion pieces
and important aspects of the facilitated discussion from the meeting ‘The indirect
effects of cytomegalovirus in...
royalsocietypublishing.org
November 7, 2025 at 8:23 AM
Reposted by Tom Yates
My beautiful laundrette
www.theguardian.com/football/202...
www.theguardian.com/football/202...
Silence over Sudan: why do Manchester City’s owners get away with so much?
Two midweek matches in England had a backdrop of war and geopolitics, but only one drew large protests
www.theguardian.com
November 8, 2025 at 11:17 AM
My beautiful laundrette
www.theguardian.com/football/202...
www.theguardian.com/football/202...
Reposted by Tom Yates
Why should we switch 2p of tax from National Insurance to Income Tax? ⤵️
Income Tax raises more money and spreads the burden more fairly. The switch would raise £6 billion, and leave the vast majority of payslips unaffected.
Income Tax raises more money and spreads the burden more fairly. The switch would raise £6 billion, and leave the vast majority of payslips unaffected.
November 7, 2025 at 11:00 AM
Why should we switch 2p of tax from National Insurance to Income Tax? ⤵️
Income Tax raises more money and spreads the burden more fairly. The switch would raise £6 billion, and leave the vast majority of payslips unaffected.
Income Tax raises more money and spreads the burden more fairly. The switch would raise £6 billion, and leave the vast majority of payslips unaffected.
Naive question
I have yield of case finding data at 0-3 months, 9-12m, 13-24m, etc, with associated estimates of uncertainty (can be converted into a set of proportions)
Precision different at different time points
How best to combine if I want e.g. yield over first two years (with CI)?
#StatSky
I have yield of case finding data at 0-3 months, 9-12m, 13-24m, etc, with associated estimates of uncertainty (can be converted into a set of proportions)
Precision different at different time points
How best to combine if I want e.g. yield over first two years (with CI)?
#StatSky
November 7, 2025 at 10:35 AM
Naive question
I have yield of case finding data at 0-3 months, 9-12m, 13-24m, etc, with associated estimates of uncertainty (can be converted into a set of proportions)
Precision different at different time points
How best to combine if I want e.g. yield over first two years (with CI)?
#StatSky
I have yield of case finding data at 0-3 months, 9-12m, 13-24m, etc, with associated estimates of uncertainty (can be converted into a set of proportions)
Precision different at different time points
How best to combine if I want e.g. yield over first two years (with CI)?
#StatSky
NEW PAPER!
Here is the intro to our theme issue, incl a summary of included papers and overview of key debates in the field
Increasing mechanistic understanding but little work robustly quantifying impact of CMV indirect effects on population health
We suggest a few ways forward!
#IDSky #ViroSky
Here is the intro to our theme issue, incl a summary of included papers and overview of key debates in the field
Increasing mechanistic understanding but little work robustly quantifying impact of CMV indirect effects on population health
We suggest a few ways forward!
#IDSky #ViroSky
The indirect effects of cytomegalovirus infection—mechanisms and consequences | Philosophical Transactions of the Royal Society B: Biological Sciences
In this introduction, we summarize the research papers, review articles, opinion pieces
and important aspects of the facilitated discussion from the meeting ‘The indirect
effects of cytomegalovirus in...
royalsocietypublishing.org
November 7, 2025 at 8:23 AM
Reposted by Tom Yates
Dear GOD if you want to save money in the asylum system
1. LET ASYLUM SEEKERS WORK
2. FAST TRACK STATUS FOR EVERYONE FROM CLEARLY UNDAFE COUNTRIES like Sudan, Syria, etc
3. Run an asylum accommodation system that is NOT FOR PROFIT #r4today
1. LET ASYLUM SEEKERS WORK
2. FAST TRACK STATUS FOR EVERYONE FROM CLEARLY UNDAFE COUNTRIES like Sudan, Syria, etc
3. Run an asylum accommodation system that is NOT FOR PROFIT #r4today
November 7, 2025 at 7:35 AM
Dear GOD if you want to save money in the asylum system
1. LET ASYLUM SEEKERS WORK
2. FAST TRACK STATUS FOR EVERYONE FROM CLEARLY UNDAFE COUNTRIES like Sudan, Syria, etc
3. Run an asylum accommodation system that is NOT FOR PROFIT #r4today
1. LET ASYLUM SEEKERS WORK
2. FAST TRACK STATUS FOR EVERYONE FROM CLEARLY UNDAFE COUNTRIES like Sudan, Syria, etc
3. Run an asylum accommodation system that is NOT FOR PROFIT #r4today
Reposted by Tom Yates
NEW JOURNAL ISSUE!
The indirect effects of cytomegalovirus infection: mechanisms and consequences
Enjoyed editing this with Helen Payne and @strangviruslab.bsky.social
Includes protocol for NIRVANA trial, which is getting started in Uganda and South Africa
#idsky #virosky
The indirect effects of cytomegalovirus infection: mechanisms and consequences
Enjoyed editing this with Helen Payne and @strangviruslab.bsky.social
Includes protocol for NIRVANA trial, which is getting started in Uganda and South Africa
#idsky #virosky
Philosophical Transactions of the Royal Society B: Biological Sciences: Vol 380, No 1938
share.google
November 6, 2025 at 10:49 AM
NEW JOURNAL ISSUE!
The indirect effects of cytomegalovirus infection: mechanisms and consequences
Enjoyed editing this with Helen Payne and @strangviruslab.bsky.social
Includes protocol for NIRVANA trial, which is getting started in Uganda and South Africa
#idsky #virosky
The indirect effects of cytomegalovirus infection: mechanisms and consequences
Enjoyed editing this with Helen Payne and @strangviruslab.bsky.social
Includes protocol for NIRVANA trial, which is getting started in Uganda and South Africa
#idsky #virosky
NEW JOURNAL ISSUE!
The indirect effects of cytomegalovirus infection: mechanisms and consequences
Enjoyed editing this with Helen Payne and @strangviruslab.bsky.social
Includes protocol for NIRVANA trial, which is getting started in Uganda and South Africa
#idsky #virosky
The indirect effects of cytomegalovirus infection: mechanisms and consequences
Enjoyed editing this with Helen Payne and @strangviruslab.bsky.social
Includes protocol for NIRVANA trial, which is getting started in Uganda and South Africa
#idsky #virosky
Philosophical Transactions of the Royal Society B: Biological Sciences: Vol 380, No 1938
share.google
November 6, 2025 at 10:49 AM
NEW JOURNAL ISSUE!
The indirect effects of cytomegalovirus infection: mechanisms and consequences
Enjoyed editing this with Helen Payne and @strangviruslab.bsky.social
Includes protocol for NIRVANA trial, which is getting started in Uganda and South Africa
#idsky #virosky
The indirect effects of cytomegalovirus infection: mechanisms and consequences
Enjoyed editing this with Helen Payne and @strangviruslab.bsky.social
Includes protocol for NIRVANA trial, which is getting started in Uganda and South Africa
#idsky #virosky
Have to say, I am tempted to do a second PhD!
We are looking for candidates for a new fully-funded joint PhD position at the Universities of Toronto and Melbourne, working on RCTs in bloodstream infection (BALANCE+, SNAP, STRAP).
More info here: forms.gle/H9TXEMkwM1cb...
Please spread far and wide!
@steventong.bsky.social #IDSky
More info here: forms.gle/H9TXEMkwM1cb...
Please spread far and wide!
@steventong.bsky.social #IDSky
forms.gle
October 27, 2025 at 9:17 AM
Have to say, I am tempted to do a second PhD!
Reposted by Tom Yates
When trains are pricier than planes, there’s a heavy social, financial and environmental cost
When trains are pricier than planes, there’s a heavy social, financial and environmental cost
In this week’s newsletter: whether it’s a holiday or work trip, railway travellers find themselves burdened by astronomical prices
www.theguardian.com
October 24, 2025 at 6:05 AM
When trains are pricier than planes, there’s a heavy social, financial and environmental cost
Good this, from @kenanmalik.bsky.social
Given status quo is unacceptable, the international community must apply overwhelming pressure to ensure one of the two potential solutions comes to pass
Cross community organising, of the kind @standing-together.bsky.social undertake, also important
Given status quo is unacceptable, the international community must apply overwhelming pressure to ensure one of the two potential solutions comes to pass
Cross community organising, of the kind @standing-together.bsky.social undertake, also important
“The most intractable problem is that neither of the two main solutions to the conflict – the creation of two states for Jews and Palestinians or a single, secular democratic state for both – is currently viable.” My @theobserveruk.bsky.social column: observer.co.uk/news/opinion...
Without a two-state solution or single state with equal r...
Both sides in the conflict are entrenched in their unwillingness to cede ground to the other
observer.co.uk
October 25, 2025 at 4:08 PM
Good this, from @kenanmalik.bsky.social
Given status quo is unacceptable, the international community must apply overwhelming pressure to ensure one of the two potential solutions comes to pass
Cross community organising, of the kind @standing-together.bsky.social undertake, also important
Given status quo is unacceptable, the international community must apply overwhelming pressure to ensure one of the two potential solutions comes to pass
Cross community organising, of the kind @standing-together.bsky.social undertake, also important
Reposted by Tom Yates
One reason why the government is in a mess is that “is that true tho?” doesn’t get anywhere near enough weight against “what do the public think?”
Home Sec describes a widely held public perception (UK is the destination of choice for asylum seekers in Europe) + endorses it as true. Home Office data shows it is not true. Whatever merits of her policy change, should not make false factual claims
www.thesun.co.uk/news/3709465...
www.thesun.co.uk/news/3709465...
Migrants come to Britain because they think we're Europe's most generous country
TODAY’S small boat numbers are shameful, and the British people deserve better. They contain a lesson: we must go further and faster to secure our borders. Under the last Conservative Government, t…
www.thesun.co.uk
October 23, 2025 at 9:46 AM
One reason why the government is in a mess is that “is that true tho?” doesn’t get anywhere near enough weight against “what do the public think?”
Reposted by Tom Yates
🎓 Thinking about a PhD in clinical trial #methodology?
We have two funded PhD opportunities for students passionate about trial design and statistical methods:
• One in estimands
• One in non-inferiority trials
🔗 More info and how to apply here: buff.ly/lCpqcF6
@mrcnihrtmrp.bsky.social
We have two funded PhD opportunities for students passionate about trial design and statistical methods:
• One in estimands
• One in non-inferiority trials
🔗 More info and how to apply here: buff.ly/lCpqcF6
@mrcnihrtmrp.bsky.social
Current Opportunities
We have an iCASE studentship available to start for the 2025/2026 academic year, and applications to our fifth round of recruitment to our DTP to start in October 2026 are now also open. Please see…
buff.ly
October 23, 2025 at 9:02 AM
🎓 Thinking about a PhD in clinical trial #methodology?
We have two funded PhD opportunities for students passionate about trial design and statistical methods:
• One in estimands
• One in non-inferiority trials
🔗 More info and how to apply here: buff.ly/lCpqcF6
@mrcnihrtmrp.bsky.social
We have two funded PhD opportunities for students passionate about trial design and statistical methods:
• One in estimands
• One in non-inferiority trials
🔗 More info and how to apply here: buff.ly/lCpqcF6
@mrcnihrtmrp.bsky.social
Reposted by Tom Yates
“Moderna is still developing the CMV vaccine for patients undergoing a bone marrow transplant.” www.statnews.com/2025/10/22/m...
Moderna says key study of its CMV vaccine, expected to be its next big win, failed
Moderna said its experimental vaccine for cytomegalovirus failed in a key trial, a significant setback for a company already facing pressure from Wall Street and Washington.
www.statnews.com
October 22, 2025 at 8:20 PM
“Moderna is still developing the CMV vaccine for patients undergoing a bone marrow transplant.” www.statnews.com/2025/10/22/m...
Reposted by Tom Yates
Switching 2p from National Insurance to Income Tax would raise £6 billion while protecting pay packets.
The increase in the state pension would mean that all pensioners with incomes below £40,000 would still be better off next year than this year.
Read 'Call of duties' now ⤵️ buff.ly/BKL1NyD
The increase in the state pension would mean that all pensioners with incomes below £40,000 would still be better off next year than this year.
Read 'Call of duties' now ⤵️ buff.ly/BKL1NyD
October 13, 2025 at 3:15 PM
Switching 2p from National Insurance to Income Tax would raise £6 billion while protecting pay packets.
The increase in the state pension would mean that all pensioners with incomes below £40,000 would still be better off next year than this year.
Read 'Call of duties' now ⤵️ buff.ly/BKL1NyD
The increase in the state pension would mean that all pensioners with incomes below £40,000 would still be better off next year than this year.
Read 'Call of duties' now ⤵️ buff.ly/BKL1NyD
October 13, 2025 at 4:28 PM
Good listen
Donald Trump has threatened to withhold federal funds from New York if Zohran Mamdani is elected mayor. Is Mamdani ready to withstand an assault from Washington? On a new episode of #NewYorkerRadio, Mamdani and David Remnick discuss. Listen here: swap.fm/l/tny-radiohour-pJlLyx
October 12, 2025 at 8:25 AM
Good listen
Reposted by Tom Yates
NEW EDITORIAL!
Me, @drjesspotter.bsky.social and Rouxjeane Venter argue
- that rapid near patient DST should be developed alongside new RRTB treatment regimens
- for changes in the design of Phase 3 treatment trials
- we must oppose unprecedented cuts to research funding and development assistance
Me, @drjesspotter.bsky.social and Rouxjeane Venter argue
- that rapid near patient DST should be developed alongside new RRTB treatment regimens
- for changes in the design of Phase 3 treatment trials
- we must oppose unprecedented cuts to research funding and development assistance
Priorities in addressing rifampicin resistant TB
Progress in testing and trial design are needed
Rifampicin is a critical component of tuberculosis (TB) treatment regimens. Recent positive developments in rifampicin resistant TB—the emergence of ne...
share.google
October 11, 2025 at 9:29 AM
NEW EDITORIAL!
Me, @drjesspotter.bsky.social and Rouxjeane Venter argue
- that rapid near patient DST should be developed alongside new RRTB treatment regimens
- for changes in the design of Phase 3 treatment trials
- we must oppose unprecedented cuts to research funding and development assistance
Me, @drjesspotter.bsky.social and Rouxjeane Venter argue
- that rapid near patient DST should be developed alongside new RRTB treatment regimens
- for changes in the design of Phase 3 treatment trials
- we must oppose unprecedented cuts to research funding and development assistance
NEW EDITORIAL!
Me, @drjesspotter.bsky.social and Rouxjeane Venter argue
- that rapid near patient DST should be developed alongside new RRTB treatment regimens
- for changes in the design of Phase 3 treatment trials
- we must oppose unprecedented cuts to research funding and development assistance
Me, @drjesspotter.bsky.social and Rouxjeane Venter argue
- that rapid near patient DST should be developed alongside new RRTB treatment regimens
- for changes in the design of Phase 3 treatment trials
- we must oppose unprecedented cuts to research funding and development assistance
Priorities in addressing rifampicin resistant TB
Progress in testing and trial design are needed
Rifampicin is a critical component of tuberculosis (TB) treatment regimens. Recent positive developments in rifampicin resistant TB—the emergence of ne...
share.google
October 11, 2025 at 9:29 AM
NEW EDITORIAL!
Me, @drjesspotter.bsky.social and Rouxjeane Venter argue
- that rapid near patient DST should be developed alongside new RRTB treatment regimens
- for changes in the design of Phase 3 treatment trials
- we must oppose unprecedented cuts to research funding and development assistance
Me, @drjesspotter.bsky.social and Rouxjeane Venter argue
- that rapid near patient DST should be developed alongside new RRTB treatment regimens
- for changes in the design of Phase 3 treatment trials
- we must oppose unprecedented cuts to research funding and development assistance
Reposted by Tom Yates
Young lives cut short on an unimaginable scale: the 18,457 children on Gaza’s list of war dead
Young lives cut short on an unimaginable scale: the 18,457 children on Gaza’s list of war dead
The children’s names below appear on a list of victims of Israel’s offensive in Gaza, maintained by health authorities in the territory. As of the end of July it ran to 60,199 names, of whom 18,457 were under 18s. Far from comprehensive, the list does not include the thousands still buried under the rubble of destroyed buildings, as well as the war’s many indirect victims
As of the end of July there were 18,457 children named on the long official list of Palestinian victims of Israel’s war in Gaza. Over almost two years, that is equivalent to bombs, bullets and shells killing a boy or girl every hour of every day.
In reality the deaths are not spaced out so evenly. Siblings, cousins and playmates are often killed together, by an airstrike or artillery shell. Even children shot by snipers or quadcopters are sometimes brought into hospitals in groups, doctors say. Continue reading...
www.theguardian.com
October 8, 2025 at 7:51 AM
Young lives cut short on an unimaginable scale: the 18,457 children on Gaza’s list of war dead
Even if you disregard likely overfitting, the tiny validation sample and whether the outcome is pathophysiologically coherent, what is this test for?
You don't need a £1000 test to distinguish folk with profound fatigue from people with normal activity levels - you can just ask them
You don't need a £1000 test to distinguish folk with profound fatigue from people with normal activity levels - you can just ask them
Scientists develop first ‘accurate blood test’ to detect chronic fatigue syndrome
Scientists develop first ‘accurate blood test’ to detect chronic fatigue syndrome
Research could offer hope for ME patients – but some experts urge caution and say more studies needed
Scientists say they have developed the world’s first blood test to diagnose myalgic encephalomyelitis, also known as chronic fatigue syndrome (ME/CFS).
There is no currently no test for the condition and patients tend to be diagnosed based on symptoms, which means many can go undiagnosed for years. Continue reading...
www.theguardian.com
October 8, 2025 at 5:47 PM
Even if you disregard likely overfitting, the tiny validation sample and whether the outcome is pathophysiologically coherent, what is this test for?
You don't need a £1000 test to distinguish folk with profound fatigue from people with normal activity levels - you can just ask them
You don't need a £1000 test to distinguish folk with profound fatigue from people with normal activity levels - you can just ask them
Reposted by Tom Yates
Reform UK’s ex-leader in Wales Nathan Gill pleads guilty to bribery charges
Reform UK’s ex-leader in Wales Nathan Gill pleads guilty to bribery charges
Gill admits to eight charges while an elected member of the European parliament
Nathan Gill, a former leader of Reform UK in Wales, has pleaded guilty at the Old Bailey to eight bribery charges while an elected member of the European parliament.
More details soon … Continue reading...
www.theguardian.com
September 26, 2025 at 12:11 PM
Reform UK’s ex-leader in Wales Nathan Gill pleads guilty to bribery charges
Powell or Phillipson? I am leaning Powell
September 26, 2025 at 8:44 PM
Powell or Phillipson? I am leaning Powell