Sophie Claudel, MD
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sophieclaudel.bsky.social
Sophie Claudel, MD
@sophieclaudel.bsky.social
510 followers 190 following 18 posts
Nephrology fellow @bu_bmc_renal @the_BMC | aspiring epidemiologist interested in mechanisms linking CKD, albuminuria, and cardiovascular disease | she/her

https://profiles.bu.edu/Sophie.Claudel
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sophieclaudel.bsky.social
I’m extremely honored to have been chosen as one of this year’s STAT Wunderkinds and grateful for the incredible support of my mentors @ashunephro.bsky.social and Sus Waikar!! @bu_bmc_renal 🎉 #nephsky

www.statnews.com/wunderkinds/
www.statnews.com
October 15, 2025 at 10:33 PM
Reposted by Sophie Claudel, MD
hswapnil.medsky.social
Design of the CURE study which we hope will disentangle the etiologies and mechanisms of CKDu (beyond mesoamerican nephropathy - there’s one site in India too, though not Sri Lanka ) www.kireports.org/article/S246... in @kireports.bsky.social
#NephSky
Visual abstract from Jade Teakell
June 30, 2025 at 12:31 PM
Reposted by Sophie Claudel, MD
hswapnil.medsky.social
The first #ERA25 simultaneous pub

CONFIDENCE trial of empagliflozin + finerenone in N = 579

Greater reduction in ACR and BP
Note the impressive GFR dip

www.nejm.org/doi/full/10....
Urinary Albumin-to-Creatinine Ratio, Serum Potassium Level, Estimated Glomerular Filtration Rate, and Systolic Blood Pressure over Time.
June 5, 2025 at 9:54 AM
Reposted by Sophie Claudel, MD
natrevneph.nature.com
ICYMI:
Cardiovascular mortality increases with stage of cardiovascular–kidney–metabolic syndrome
Nature Reviews Nephrology, Published online: 31 March 2025; doi:10.1038/s41581-025-00957-yCardiovascular mortality increases with stage of cardiovascular–kidney–metabolic syndrome
www.nature.com
April 5, 2025 at 10:55 PM
sophieclaudel.bsky.social
Thank you @asnkidney.bsky.social for highlighting our work!

@ashunephro.bsky.social
asnpublications.bsky.social ASN Publications @asnpublications.bsky.social · Mar 27
Cumulative Incidence of Mortality (CKM) syndrome stages 1 to 4 are associated with a graded risk of cardiovascular mortality in a nationally representative sample of U.S. adults. https://bit.ly/JASN0637
#ASNJASN
@ashunephro.bsky.social
@sophieclaudel.bsky.social
March 27, 2025 at 8:12 PM
sophieclaudel.bsky.social
Learned quite a lot about interactions, thresholds, and synergistic effects from @ashunephro.bsky.social in this analysis of albuminuria, heart failure, and CKD progression. Our findings emphasize albuminuria as a key biomarker for CKM health. 🫘
@jaccjournals.bsky.social #NephSky
ashunephro.bsky.social Ashish Verma @ashunephro.bsky.social · Mar 24
Delighted to share our study published in @jaccjournals.bsky.social led by @sophieclaudel.bsky.social. We demonstrated deleterious synergy between albuminuria and heart failure as risk factors for CKD progression.
www.jacc.org/doi/10.1016/...
March 25, 2025 at 9:40 PM
sophieclaudel.bsky.social
Thank you @danieljdrucker.bsky.social !!
March 11, 2025 at 12:43 PM
sophieclaudel.bsky.social
Extremely grateful to @ahascience.bsky.social and @ashunephro.bsky.social for the opportunity to publish this comprehensive review on albuminuria in #Circulation. We cover albuminuria in the spectrum of #CKM disorders. Please take a look!
@nephjc.bsky.social #NephSky
ashunephro.bsky.social Ashish Verma @ashunephro.bsky.social · Mar 10
Thrilled to share our state of art review led by extraordinary @sophieclaudel.bsky.social
“Albuminuria in Cardiovascular, Kidney, and Metabolic Disorders: A State-of-the-Art Review"
www.ahajournals.org/eprint/SXXGK...

@ahascience.bsky.social
@ahajournals.bsky.social
@asnkidney.bsky.social
March 11, 2025 at 12:42 PM
sophieclaudel.bsky.social
Very proud of our #BMCimRes internal medicine residents for coming up with this project idea and seeing it through to publication! We looked at current statin prescribing practices for young adults in the US and their CVD risk.

authors.elsevier.com/a/1khiu2gOwG...
authors.elsevier.com
March 3, 2025 at 12:16 AM
sophieclaudel.bsky.social
Excited to share this research letter looking at albuminuria values in healthy adults! We followed IFCC guidelines for establishing references ranges, which had not previously been shown in the literature, and consider what “normal” should be by sex.
ashunephro.bsky.social Ashish Verma @ashunephro.bsky.social · Feb 21
We sought to quantify the upper limit of normal for albuminuria among US adults by the IFCC standard. Our study led by @sophieclaudel.bsky.social “Albuminuria References Ranges in Healthy US Adults”

academic.oup.com/jalm/advance...
Albuminuria References Ranges in Healthy US Adults
To the Editor:
academic.oup.com
February 22, 2025 at 1:20 PM
sophieclaudel.bsky.social
Very proud of this project that started as a casual conversation on #CKM syndrome with @ashunephro.bsky.social over a year ago and is now in print at #JASN! Couldn’t have done it without @ashunephro.bsky.social teaching me about cumulative incidence curves in #NHANES.
February 11, 2025 at 6:56 PM
Reposted by Sophie Claudel, MD
ashunephro.bsky.social
Thrilled to share our publication led by exceptional @sophieclaudel.bsky.social "Cumulative Incidence of Mortality Associated with Cardiovascular-Kidney-Metabolic Syndrome" in @asnpublications.bsky.social journals.lww.com/jasn/abstrac... @asnkidney.bsky.social @americanheart.bsky.social
Cumulative Incidence of Mortality Associated with... : Journal of the American Society of Nephrology
e corresponding restricted mean survival time over a 15-year period. Methods: This is a longitudinal study of 50,678 community-dwelling U.S. adults aged 20 and older with baseline data for CKM stag...
journals.lww.com
February 11, 2025 at 5:38 PM
Reposted by Sophie Claudel, MD
yonahfreemark.com
The US DOT says it's planning to prioritize areas with high marriage & high birth rates for funding.

Our new analysis @urbaninstitute.bsky.social shows this would disproportionately fund:
—Communities with a higher white resident share
—Low-density areas
—High-income areas
—Car-dependent areas
DOT’s Plan to Distribute Funding by Birth and Marriage Rates Would Leave Communities Most In Need Behind
If enacted, the new US Department of Transportation memo would prioritize funding to whiter, higher-income, more car-dependent areas over communities of color and people who walk, bike, or take public...
www.urban.org
February 10, 2025 at 4:04 PM
sophieclaudel.bsky.social
Hyperaldosteronism in CKD (and CVD) is something I’ve been trying to learn more about recently. Hoping to join tonight! #nephjc
February 11, 2025 at 11:55 AM
sophieclaudel.bsky.social
Very proud of this work! Thanks to @ashunephro.bsky.social and co-mentors for their support of this project
ashunephro.bsky.social Ashish Verma @ashunephro.bsky.social · Jan 6
Adults with higher levels of albuminuria within the low range (UACR <30 mg/g) and no major cardiovascular risk factors have higher risks of cardiovascular and all-cause mortality. academic.oup.com/eurjpc/artic... @sophieclaudel.bsky.social
January 6, 2025 at 11:21 PM
sophieclaudel.bsky.social
Very excited to share this work by my mentor Dr. Ashish Verma and me on #SDOH and #mortality among adults *without* major chronic diseases published in @JGIM! We looked at food insecurity, employment, income, acculturation, education and healthcare access.

link.springer.com/article/10.1...
Social Determinants of Health and Cumulative Incidence of Mortality Among US Adults Without Major Chronic Diseases - Journal of General Internal Medicine
Background Social determinants of health (SDOH) are associated with poor health outcomes among individuals with prevalent diseases. Objective To quantify the association between adverse SDOH and morta...
link.springer.com
December 12, 2024 at 2:07 PM
sophieclaudel.bsky.social
The post-Thanksgiving consult bolus is real… 🧂
November 30, 2024 at 12:37 AM
sophieclaudel.bsky.social
Sophie, enjoying life as a renal fellow in Boston. No COI #NephJC
November 20, 2024 at 2:18 AM