Shannon McKinney-Freeman
@smckinneyfreeman.bsky.social
Member in Hematology at St. Jude Children’s Research Hospital. Interested in hematopoietic stem cells, hematopoiesis, ontogeny and development, aging, transplant, sickle cell disease, and my four kids. Yay ISEH!
Pinned
If anyone wants to know how Judge Biery felt about this, here's his sig block:
Judge Biery is a badass and my hero
Noooooo!!!! Not JJJ!!!!!!
The Memphis Grizzlies traded Jaren Jackson Jr. and three other players to the Utah Jazz.
Grizzlies trade Jaren Jackson Jr.
The Memphis Grizzlies traded Jaren Jackson Jr. and three other players to the Utah Jazz.
dailymemphian.com
February 3, 2026 at 7:39 PM
Noooooo!!!! Not JJJ!!!!!!
Reposted by Shannon McKinney-Freeman
When you agree to serve in a committee
February 3, 2026 at 2:22 PM
When you agree to serve in a committee
Judge Biery is a badass and my hero
If anyone wants to know how Judge Biery felt about this, here's his sig block:
February 1, 2026 at 2:46 PM
Judge Biery is a badass and my hero
Reposted by Shannon McKinney-Freeman
“I just checked—it turns out that Art. II, Sec. 1 of the Constitution of the United States does *not* say ‘The executive Power shall be vested in a bunch of sociopaths who think they can do whatever the f*ck they want and make sh*t up as they go along.’” — George Conway
January 26, 2026 at 12:37 PM
“I just checked—it turns out that Art. II, Sec. 1 of the Constitution of the United States does *not* say ‘The executive Power shall be vested in a bunch of sociopaths who think they can do whatever the f*ck they want and make sh*t up as they go along.’” — George Conway
Reposted by Shannon McKinney-Freeman
If this nation has a conscience, what will it take to shake it from its slumber?
A video of Alex Pretti reading out the final salute of an unnamed veteran he cared for until the end of his life in the ICU, posted to Facebook by his son.
January 25, 2026 at 9:32 PM
If this nation has a conscience, what will it take to shake it from its slumber?
Reposted by Shannon McKinney-Freeman
An unexpected topic I encountered during my PhD: tricellular junctions.
I first knew them as local regulators of tissue mechanics, but over time have realised their broader impact at the tissue scale.
I wrote a brief overview of this in a thread for @epimechfc.bsky.social.
I first knew them as local regulators of tissue mechanics, but over time have realised their broader impact at the tissue scale.
I wrote a brief overview of this in a thread for @epimechfc.bsky.social.
How can structures at the vertex of 3 cells have effects at the tissue level?
Join me, @laura-rustarazo.bsky.social, to explore how tricellular junctions (TCJs) act as local tension sensors and regulators of global tissue organization. 🧵⤵️ doi.org/10.1126/scie...
Join me, @laura-rustarazo.bsky.social, to explore how tricellular junctions (TCJs) act as local tension sensors and regulators of global tissue organization. 🧵⤵️ doi.org/10.1126/scie...
January 20, 2026 at 7:28 PM
An unexpected topic I encountered during my PhD: tricellular junctions.
I first knew them as local regulators of tissue mechanics, but over time have realised their broader impact at the tissue scale.
I wrote a brief overview of this in a thread for @epimechfc.bsky.social.
I first knew them as local regulators of tissue mechanics, but over time have realised their broader impact at the tissue scale.
I wrote a brief overview of this in a thread for @epimechfc.bsky.social.
Reposted by Shannon McKinney-Freeman
Here is a picture of a baby otter for no good reason.
January 17, 2026 at 6:01 PM
Here is a picture of a baby otter for no good reason.
Reposted by Shannon McKinney-Freeman
Lots of problems with multi year funding mechanism. Far fewer grants can be funded and they can only be funded for 4, not 5 years even though most grants funded by the normal mechanism are 5 years. It’s a back door way for Russell Vought to choke off science funding
At least prior to 2025, you could expect all years on your grant (barring major issues).
The main problem with MYF is the rapid transition absent an NIH budget increase. We can pay 4 grants for 1 year, or only 1 grant for 4 years. Under MYF, we can pay far fewer grants (1 instead of 4).
The main problem with MYF is the rapid transition absent an NIH budget increase. We can pay 4 grants for 1 year, or only 1 grant for 4 years. Under MYF, we can pay far fewer grants (1 instead of 4).
January 17, 2026 at 8:17 PM
Lots of problems with multi year funding mechanism. Far fewer grants can be funded and they can only be funded for 4, not 5 years even though most grants funded by the normal mechanism are 5 years. It’s a back door way for Russell Vought to choke off science funding
Have you ever wondered about Pig HSCs? Today is your lucky day! Check out this excellent work from @ganuzalab.bsky.social. Well done!
Pig and human adult hematopoietic stem and progenitor cells are overall transcriptionally similar. www.exphem.org/article/S030...
@isehsociety.bsky.social
Pig and human adult hematopoietic stem and progenitor cells are overall transcriptionally similar. www.exphem.org/article/S030...
@isehsociety.bsky.social
Pig and human adult hematopoietic stem and progenitor cells are overall transcriptionally similar
Allotransplantation provides a lifesaving treatment to hundreds of thousands of patients
worldwide every year, including among others heart, kidney, liver and bone marrow
(BM) transplants [1,2]. Yet, ...
www.exphem.org
January 17, 2026 at 1:53 PM
Have you ever wondered about Pig HSCs? Today is your lucky day! Check out this excellent work from @ganuzalab.bsky.social. Well done!
Pig and human adult hematopoietic stem and progenitor cells are overall transcriptionally similar. www.exphem.org/article/S030...
@isehsociety.bsky.social
Pig and human adult hematopoietic stem and progenitor cells are overall transcriptionally similar. www.exphem.org/article/S030...
@isehsociety.bsky.social
The struggle is real! Studying HSCs during inflammatory is a challenge as their phenotype changes. Check out this excellent new work in Experimental Hematology reporting another useful tool for identifying HSCs under these conditions. www.exphem.org/article/S030...
@isehsociety.bsky.social
@isehsociety.bsky.social
Endothelial protein C receptor CD201 is a better marker than stem cell antigen-1 to identify mouse long-term reconstituting hematopoietic stem cells following septic challenge
Stem cell antigen 1 (SCA1) has been used for decades to separate mouse hematopoietic
stem and progenitor cell subsets; however, it fails to do so when mice are challenged
by pathogens, interferons, or...
www.exphem.org
January 17, 2026 at 1:48 PM
The struggle is real! Studying HSCs during inflammatory is a challenge as their phenotype changes. Check out this excellent new work in Experimental Hematology reporting another useful tool for identifying HSCs under these conditions. www.exphem.org/article/S030...
@isehsociety.bsky.social
@isehsociety.bsky.social
It’s so special to be nominated for this by my trainees. Their hard work makes my job easy and I am so grateful to work with them every day. Mentorship is hard and I benefit from the awesome example of my own fantastic mentors. Thank you Colleen, Peggy @goodell-lab.bsky.social and George!
St. Jude congratulates Shannon McKinney-Freeman, PhD, on being named the 2025 Postdoctoral Association Mentor of the Year. Nominated by four mentees, McKinney-Freeman is recognized for her dedication to advancing the next generation of scientists.
#MentoringMonth
#MentoringMonth
January 17, 2026 at 1:36 PM
It’s so special to be nominated for this by my trainees. Their hard work makes my job easy and I am so grateful to work with them every day. Mentorship is hard and I benefit from the awesome example of my own fantastic mentors. Thank you Colleen, Peggy @goodell-lab.bsky.social and George!
Reposted by Shannon McKinney-Freeman
Gratitutde to all NIH study section participants who are participating in rescheduled meetings now and in January. Thank you for your service and thanks also to the hard working NIH staff who are making these happen. 🥰🧪
December 5, 2025 at 8:46 PM
Gratitutde to all NIH study section participants who are participating in rescheduled meetings now and in January. Thank you for your service and thanks also to the hard working NIH staff who are making these happen. 🥰🧪
Reposted by Shannon McKinney-Freeman
For decades, the mystery of how DICER1 mutations promote pediatric rhabdomyosarcoma remained unsolved. Mark Hatley, MD, PhD, and his lab cracked the case, powered by advancements in single-cell RNA sequencing, revealing new paths for intervention. https://ow.ly/UiCG50XU294
January 9, 2026 at 6:02 PM
For decades, the mystery of how DICER1 mutations promote pediatric rhabdomyosarcoma remained unsolved. Mark Hatley, MD, PhD, and his lab cracked the case, powered by advancements in single-cell RNA sequencing, revealing new paths for intervention. https://ow.ly/UiCG50XU294
Reposted by Shannon McKinney-Freeman
NIH grant applicants:
October and November grant application submission *deadlines* will be rescheduled (🤯). Specific dates TBD.
grants.nih.gov/grants/guide...
October and November grant application submission *deadlines* will be rescheduled (🤯). Specific dates TBD.
grants.nih.gov/grants/guide...
NOT-OD-26-005: Interim Guidance on Reopening of NIH Extramural Activities
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Interim Guidance on Reopening of NIH Extramural Activities NOT-OD-26-005. NIH
grants.nih.gov
November 14, 2025 at 8:45 PM
NIH grant applicants:
October and November grant application submission *deadlines* will be rescheduled (🤯). Specific dates TBD.
grants.nih.gov/grants/guide...
October and November grant application submission *deadlines* will be rescheduled (🤯). Specific dates TBD.
grants.nih.gov/grants/guide...
New issue of Experimental Hematology out! Check it out! Articles on novel molecular markers of HSCs, engineering red cells from sickle cell disease-derived iPSCs, and classifying HSPCs in LR-MDS.
www.exphem.org/issue/S0301-...
www.exphem.org/issue/S0301-...
Current Issue Table of Contents: Experimental Hematology
www.exphem.org
November 19, 2025 at 12:09 PM
New issue of Experimental Hematology out! Check it out! Articles on novel molecular markers of HSCs, engineering red cells from sickle cell disease-derived iPSCs, and classifying HSPCs in LR-MDS.
www.exphem.org/issue/S0301-...
www.exphem.org/issue/S0301-...
Reposted by Shannon McKinney-Freeman
Join the Junior Faculty Career Session: Meet the Editors: Insights from Behind the Scenes.
Attend this free session during the lunch hour on Thursday, 25 September at #ISEH2025 🏯!
iseh.org/Annual-Meeting/54th-Annual-Meeting/Registration
Attend this free session during the lunch hour on Thursday, 25 September at #ISEH2025 🏯!
iseh.org/Annual-Meeting/54th-Annual-Meeting/Registration
September 17, 2025 at 3:31 PM
Join the Junior Faculty Career Session: Meet the Editors: Insights from Behind the Scenes.
Attend this free session during the lunch hour on Thursday, 25 September at #ISEH2025 🏯!
iseh.org/Annual-Meeting/54th-Annual-Meeting/Registration
Attend this free session during the lunch hour on Thursday, 25 September at #ISEH2025 🏯!
iseh.org/Annual-Meeting/54th-Annual-Meeting/Registration
Reposted by Shannon McKinney-Freeman
Join the Junior Faculty Committee at their FREE 22 October webinar on Responsible AI in Research and Publishing featuring Laura Watts, PhD from @lumanity.bsky.social and @p4sc4l.substack.com from Wiley. Learn more and register 👉 iseh.org/Webinars-Eve...
September 18, 2025 at 3:03 PM
Join the Junior Faculty Committee at their FREE 22 October webinar on Responsible AI in Research and Publishing featuring Laura Watts, PhD from @lumanity.bsky.social and @p4sc4l.substack.com from Wiley. Learn more and register 👉 iseh.org/Webinars-Eve...
Reposted by Shannon McKinney-Freeman
Super excited to attend the 54th @isehsociety.bsky.social
conference in Japan next week! First time in Japan. First time at a hematology conference. Great chance to network with the world's best and share our CH work in Down Syndrome.
@crnicinstitute.bsky.social @cuanschutz.bsky.social
conference in Japan next week! First time in Japan. First time at a hematology conference. Great chance to network with the world's best and share our CH work in Down Syndrome.
@crnicinstitute.bsky.social @cuanschutz.bsky.social
September 18, 2025 at 10:55 PM
Super excited to attend the 54th @isehsociety.bsky.social
conference in Japan next week! First time in Japan. First time at a hematology conference. Great chance to network with the world's best and share our CH work in Down Syndrome.
@crnicinstitute.bsky.social @cuanschutz.bsky.social
conference in Japan next week! First time in Japan. First time at a hematology conference. Great chance to network with the world's best and share our CH work in Down Syndrome.
@crnicinstitute.bsky.social @cuanschutz.bsky.social
Reposted by Shannon McKinney-Freeman
Enjoying Japan’s autumn flavors together yesterday after a full day of teamwork & remarkable effort toward multi-year strategic planning for @isehsociety.bsky.social, future scientists, and the prestige of #ExpHem. @thekinglab.bsky.social @smckinneyfreeman.bsky.social @einsteinmededu.bsky.social
September 24, 2025 at 8:42 AM
Enjoying Japan’s autumn flavors together yesterday after a full day of teamwork & remarkable effort toward multi-year strategic planning for @isehsociety.bsky.social, future scientists, and the prestige of #ExpHem. @thekinglab.bsky.social @smckinneyfreeman.bsky.social @einsteinmededu.bsky.social
Hard to think of a better group of people to work with towards a strong future for the ISEH. The BEST society for folks interested in the fundamentals of hematopoiesis and HSC Biology. @isehsociety.bsky.social
Ready for #ISEH2025 Scientific Session? After 1.5 days of rich, productive discussions, @isehsociety.bsky.social leadership & Board of Directors are all set—with the full program and even the social events lined up!
@thekinglab.bsky.social @smckinneyfreeman.bsky.social @nickvangastel.bsky.social
@thekinglab.bsky.social @smckinneyfreeman.bsky.social @nickvangastel.bsky.social
September 24, 2025 at 8:17 PM
Hard to think of a better group of people to work with towards a strong future for the ISEH. The BEST society for folks interested in the fundamentals of hematopoiesis and HSC Biology. @isehsociety.bsky.social
Reposted by Shannon McKinney-Freeman
Memphis Mayor Paul Young confirmed reports that Gov. Bill Lee and the White House were in talks to send National Guard troops to Memphis.
WKNO Daily Newscast | Friday, September 12, 2025
Memphis Mayor Paul Young confirmed reports that Gov. Bill Lee and the White House were in talks to send National Guard troops to Memphis.
buff.ly
September 12, 2025 at 6:15 PM
Memphis Mayor Paul Young confirmed reports that Gov. Bill Lee and the White House were in talks to send National Guard troops to Memphis.
Reposted by Shannon McKinney-Freeman
This year's Lasker Awards went to scientists who studied the wiring diagram of life, a new state of biological matter, and a potent treatment for cystic fibrosis. Here's my story with Gina Kolata. Gift link: nyti.ms/4mZlH1F
nyti.ms
September 11, 2025 at 1:30 PM
This year's Lasker Awards went to scientists who studied the wiring diagram of life, a new state of biological matter, and a potent treatment for cystic fibrosis. Here's my story with Gina Kolata. Gift link: nyti.ms/4mZlH1F
This is a really important analysis. Scientists in the US need to pay attention.
So... I did some analysis of grants that did receive noncompetitive renewals.
In particular, I looked a those award where the title of the grant changed.
Warning: The results are just what I expected, but oooph...
1/4
In particular, I looked a those award where the title of the grant changed.
Warning: The results are just what I expected, but oooph...
1/4
a man with his eyes closed is wearing a plaid shirt and a blue jacket .
ALT: a man with his eyes closed is wearing a plaid shirt and a blue jacket .
media.tenor.com
September 10, 2025 at 6:26 PM
This is a really important analysis. Scientists in the US need to pay attention.
The ISEH just launched a brand new website! Check it out and join our society today to network with your colleagues and keep abreast of the latest advances in basic and translational experimental hematology research!
iseh.org
iseh.org
Home
iseh.org
September 10, 2025 at 6:22 PM
The ISEH just launched a brand new website! Check it out and join our society today to network with your colleagues and keep abreast of the latest advances in basic and translational experimental hematology research!
iseh.org
iseh.org
Still time to register for the annual ISEH meeting! No better place to learn about the latest advances in fundamental HSC biology!
Less than a month to go until #ISEH2025!
@mjassinskaja.bsky.social from @lundstem.bsky.social is looking forward to catching up with her international collaborators at #ISEH2025 🏯. Take advantage of this opportunity to connect with your colleagues from around the world and register! www.iseh.org/2025Registration
September 8, 2025 at 2:24 PM
Still time to register for the annual ISEH meeting! No better place to learn about the latest advances in fundamental HSC biology!