Shudong Li
@shudongli.bsky.social
Postdoc in the Boulton Lab at the Francis Crick Institute. Currently working on dna damage.
Reposted by Shudong Li
I'm very excited that my first postdoc paper is out now at @nature.com!
www.nature.com/articles/s41...
I developed new single cell CDK sensors to investigate how CDK orchestrates mitosis including investigating bistability/hysteresis, how activity is propagated, and the role of centrosomes.
www.nature.com/articles/s41...
I developed new single cell CDK sensors to investigate how CDK orchestrates mitosis including investigating bistability/hysteresis, how activity is propagated, and the role of centrosomes.
Spatiotemporal orchestration of mitosis by cyclin-dependent kinase - Nature
Experiments in fission yeast show that cyclin-dependent kinase is first activated in the nucleus, from which the mitotic signal is propagated from CDK at the centrosome to the cytoplasm.
www.nature.com
June 25, 2025 at 5:12 PM
I'm very excited that my first postdoc paper is out now at @nature.com!
www.nature.com/articles/s41...
I developed new single cell CDK sensors to investigate how CDK orchestrates mitosis including investigating bistability/hysteresis, how activity is propagated, and the role of centrosomes.
www.nature.com/articles/s41...
I developed new single cell CDK sensors to investigate how CDK orchestrates mitosis including investigating bistability/hysteresis, how activity is propagated, and the role of centrosomes.
Merry Boulton Lab Retreat! Great fun team building and going over some hot topics in DDR/chromatin/immune biology. Same again next year please! @mattdnewton.bsky.social @ssegurabayona.bsky.social @federicaraguseo.bsky.social @claralnovo.bsky.social
December 15, 2024 at 8:21 AM
Merry Boulton Lab Retreat! Great fun team building and going over some hot topics in DDR/chromatin/immune biology. Same again next year please! @mattdnewton.bsky.social @ssegurabayona.bsky.social @federicaraguseo.bsky.social @claralnovo.bsky.social
Thank you @promegauk.bsky.social for the Christmas hamper
December 5, 2024 at 8:20 AM
Thank you @promegauk.bsky.social for the Christmas hamper
Reposted by Shudong Li
Happy to share a review written with the wonderful @jstingele.bsky.social on transcription-coupled DPC repair, featuring an overview of new methods, close comparison with TC-NER, comments on clinical implications and plenty of discussion of the unknowns.
www.cell.com/trends/cell-...
www.cell.com/trends/cell-...
Transcription-coupled repair of DNA–protein crosslinks
DNA–protein crosslinks (DPCs) are highly toxic DNA lesions that are relevant to multiple
human diseases. They are caused by various endogenous and environmental agents, and
from the actions of enzymes...
www.cell.com
December 2, 2024 at 7:39 AM
Happy to share a review written with the wonderful @jstingele.bsky.social on transcription-coupled DPC repair, featuring an overview of new methods, close comparison with TC-NER, comments on clinical implications and plenty of discussion of the unknowns.
www.cell.com/trends/cell-...
www.cell.com/trends/cell-...
Reposted by Shudong Li
“In this Review, we discuss #telomere protection, maintenance and damage. We highlight the differences between #human and #mouse telomere biology that may contribute to discrepancies between human #diseases and mouse models.” #telomerase #aging
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Telomere function and regulation from mouse models to human ageing and disease - Nature Reviews Molecular Cell Biology
Telomere dysfunction, usually owing to shortening, activates cellular senescence and can contribute to age-associated diseases and cancer. Mouse models are crucial for telomere research, but human and...
www.nature.com
November 30, 2024 at 6:02 AM
“In this Review, we discuss #telomere protection, maintenance and damage. We highlight the differences between #human and #mouse telomere biology that may contribute to discrepancies between human #diseases and mouse models.” #telomerase #aging
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Shudong Li
Here is a brief summary of academic journals and news account.
Please help me add more accounts to this list!
go.bsky.app/hCfhqn
Please help me add more accounts to this list!
go.bsky.app/hCfhqn
November 30, 2024 at 3:21 AM
Here is a brief summary of academic journals and news account.
Please help me add more accounts to this list!
go.bsky.app/hCfhqn
Please help me add more accounts to this list!
go.bsky.app/hCfhqn
Reposted by Shudong Li
Good thing the #CBIAS2024 organizers sent a plan to reach the @thecrick.bsky.social , I almost missed the tiny building
November 25, 2024 at 9:21 AM
Good thing the #CBIAS2024 organizers sent a plan to reach the @thecrick.bsky.social , I almost missed the tiny building
Reposted by Shudong Li
Here’s my spreadsheet of starter packs (>80!) related to broadly ‘mechanistic biology’ plus some intriguing extras
Complete with collective nouns
I’ve been tracking these but now can’t keep up
Hope it’s helpful
2/2
docs.google.com/spreadsheets...
Complete with collective nouns
I’ve been tracking these but now can’t keep up
Hope it’s helpful
2/2
docs.google.com/spreadsheets...
@mjafreeman.bsky.social's BlueSky starter packs for 'mechanistic' biologists
docs.google.com
November 19, 2024 at 9:58 PM
Here’s my spreadsheet of starter packs (>80!) related to broadly ‘mechanistic biology’ plus some intriguing extras
Complete with collective nouns
I’ve been tracking these but now can’t keep up
Hope it’s helpful
2/2
docs.google.com/spreadsheets...
Complete with collective nouns
I’ve been tracking these but now can’t keep up
Hope it’s helpful
2/2
docs.google.com/spreadsheets...
First post is to introduce Pablo to bluesky. Science will follow.
November 19, 2024 at 8:01 AM
First post is to introduce Pablo to bluesky. Science will follow.
Reposted by Shudong Li
GS II is here! Please follow the newly arrived folks, and comment/DM to be included!
go.bsky.app/VeCmq6
go.bsky.app/VeCmq6
November 18, 2024 at 6:44 PM
GS II is here! Please follow the newly arrived folks, and comment/DM to be included!
go.bsky.app/VeCmq6
go.bsky.app/VeCmq6
Reposted by Shudong Li
ok, I tried to make a starter pack on genome stability/DNA replication/DNA repair etc. Sorry if I couldn't find someone, please nominate yourself and your colleagues in comments or DMs, looking forward to connecting with everyone!
go.bsky.app/9jdDNxG
go.bsky.app/9jdDNxG
November 12, 2024 at 1:11 AM
ok, I tried to make a starter pack on genome stability/DNA replication/DNA repair etc. Sorry if I couldn't find someone, please nominate yourself and your colleagues in comments or DMs, looking forward to connecting with everyone!
go.bsky.app/9jdDNxG
go.bsky.app/9jdDNxG
Reposted by Shudong Li
Hi BlueSky! It's great to be here. Here's a handy Starter Pack of DNA repair & genome stability groups that I found so far go.bsky.app/NvFWKvL
November 13, 2024 at 9:03 AM
Hi BlueSky! It's great to be here. Here's a handy Starter Pack of DNA repair & genome stability groups that I found so far go.bsky.app/NvFWKvL