ShinyBlackShoe (Calum Polwart)
@shinyblackshoe.bsky.social
🏴 consultant #oncology pharmacist working in 🏴 🇬🇧. #PharmSky #OncoSky
Interested in #OncoPharm, Data science, #Rstats, Visualisation. ⛵🍝🥌🏞️📷🖥️
Self declared geek.
Breast #bcsm, Prostate #pcsm, Lower GI #crcsm, Upper GI #esocsm & HPB #hpbcsm
chemo.org.uk
Interested in #OncoPharm, Data science, #Rstats, Visualisation. ⛵🍝🥌🏞️📷🖥️
Self declared geek.
Breast #bcsm, Prostate #pcsm, Lower GI #crcsm, Upper GI #esocsm & HPB #hpbcsm
chemo.org.uk
Pinned
If you post about Oncology Pharmacy #OncoPharm here is a Starter Pack. If you want added to it let me know.
#PharmSky
Good luck. Hope this side of the fence is nicer. 🤞🏻
go.bsky.app/USU71ai
#PharmSky
Good luck. Hope this side of the fence is nicer. 🤞🏻
go.bsky.app/USU71ai
Reposted by ShinyBlackShoe (Calum Polwart)
“While you are on chemotherapy …” Myths:
- Avoid large social gatherings
- Wash clothes w body fluids STAT
- Use a separate toilet
- Avoid all EtOH
- Avoid certain foods, coffee
--> lack evidence, cause harm academic.oup.com/jnci/article... great article from @csoncol.bsky.social #oncology
- Avoid large social gatherings
- Wash clothes w body fluids STAT
- Use a separate toilet
- Avoid all EtOH
- Avoid certain foods, coffee
--> lack evidence, cause harm academic.oup.com/jnci/article... great article from @csoncol.bsky.social #oncology
“While you are on chemotherapy …”: common recommendations that lack evidence and may cause harm
Abstract. Patients on chemotherapy often use multiple resources to obtain information on wide-ranging issues, including prognosis, treatments, diet, exerci
academic.oup.com
November 18, 2025 at 5:17 AM
“While you are on chemotherapy …” Myths:
- Avoid large social gatherings
- Wash clothes w body fluids STAT
- Use a separate toilet
- Avoid all EtOH
- Avoid certain foods, coffee
--> lack evidence, cause harm academic.oup.com/jnci/article... great article from @csoncol.bsky.social #oncology
- Avoid large social gatherings
- Wash clothes w body fluids STAT
- Use a separate toilet
- Avoid all EtOH
- Avoid certain foods, coffee
--> lack evidence, cause harm academic.oup.com/jnci/article... great article from @csoncol.bsky.social #oncology
www.ft.com/content/5d6f...
Wow. Rarely do I see a comments section so polarised.
"Charitable" sponsorship offering "access" to key people is dodgy in my eyes. It's interesting sitting on the sidelines watching this stuff. Having previously been among it. You don't see conflict you are among
Wow. Rarely do I see a comments section so polarised.
"Charitable" sponsorship offering "access" to key people is dodgy in my eyes. It's interesting sitting on the sidelines watching this stuff. Having previously been among it. You don't see conflict you are among
UK military top brass mix with defence executives at luxury Alpine event
Details of armed forces and industry attendees at Méribel competition raise concerns about conflicts of interest
www.ft.com
November 7, 2025 at 7:25 AM
www.ft.com/content/5d6f...
Wow. Rarely do I see a comments section so polarised.
"Charitable" sponsorship offering "access" to key people is dodgy in my eyes. It's interesting sitting on the sidelines watching this stuff. Having previously been among it. You don't see conflict you are among
Wow. Rarely do I see a comments section so polarised.
"Charitable" sponsorship offering "access" to key people is dodgy in my eyes. It's interesting sitting on the sidelines watching this stuff. Having previously been among it. You don't see conflict you are among
Reposted by ShinyBlackShoe (Calum Polwart)
It’s 2025 and we’re still dosing drugs like it’s 1976.
The saga of Cockcroft–Gault, FDA inertia, and the slow evolution of renal dosing equations.
🧮 pbfluids.com/2025/10/cock...
The saga of Cockcroft–Gault, FDA inertia, and the slow evolution of renal dosing equations.
🧮 pbfluids.com/2025/10/cock...
October 26, 2025 at 3:45 PM
It’s 2025 and we’re still dosing drugs like it’s 1976.
The saga of Cockcroft–Gault, FDA inertia, and the slow evolution of renal dosing equations.
🧮 pbfluids.com/2025/10/cock...
The saga of Cockcroft–Gault, FDA inertia, and the slow evolution of renal dosing equations.
🧮 pbfluids.com/2025/10/cock...
Every time I use a TV keyboard (you know the ones - remote control ABC move right right right right down down enter left left left left up up enter...)
I think surely someone should have worked out the qwerty equivalent.
I think surely someone should have worked out the qwerty equivalent.
October 19, 2025 at 1:56 PM
Every time I use a TV keyboard (you know the ones - remote control ABC move right right right right down down enter left left left left up up enter...)
I think surely someone should have worked out the qwerty equivalent.
I think surely someone should have worked out the qwerty equivalent.
Reposted by ShinyBlackShoe (Calum Polwart)
#ESMO25
Adam Gripping of @mdanderson.bsky.social discusses association of improved OS in #NSCLC and #Melanoma with administration of a mRNA COVID vaccine
Translational work showing mechanism of increased INF-alpha leading to immune priming
Phase III in development… @oncoalert.bsky.social
Adam Gripping of @mdanderson.bsky.social discusses association of improved OS in #NSCLC and #Melanoma with administration of a mRNA COVID vaccine
Translational work showing mechanism of increased INF-alpha leading to immune priming
Phase III in development… @oncoalert.bsky.social
October 19, 2025 at 1:22 PM
#ESMO25
Adam Gripping of @mdanderson.bsky.social discusses association of improved OS in #NSCLC and #Melanoma with administration of a mRNA COVID vaccine
Translational work showing mechanism of increased INF-alpha leading to immune priming
Phase III in development… @oncoalert.bsky.social
Adam Gripping of @mdanderson.bsky.social discusses association of improved OS in #NSCLC and #Melanoma with administration of a mRNA COVID vaccine
Translational work showing mechanism of increased INF-alpha leading to immune priming
Phase III in development… @oncoalert.bsky.social
Oh god. Someone better warm up the cat scanners and have the Methyl Pred on standby
Impressive results. Let's hope it's affordable and deliverable.
Impressive results. Let's hope it's affordable and deliverable.
✨#ESMO25✨
🚨 BREAKING: DESTINY-Breast05 Phase III Results!
🎗️ Enhertu (trastuzumab deruxtecan) reduced the risk of recurrence or death by 53% vs. T-DM1 in high-risk HER2+ early breast cancer after neoadjuvant therapy.
🌟 Over 92% of patients on Enhertu remained free of invasive disease at 3 years.
🚨 BREAKING: DESTINY-Breast05 Phase III Results!
🎗️ Enhertu (trastuzumab deruxtecan) reduced the risk of recurrence or death by 53% vs. T-DM1 in high-risk HER2+ early breast cancer after neoadjuvant therapy.
🌟 Over 92% of patients on Enhertu remained free of invasive disease at 3 years.
October 19, 2025 at 12:48 PM
Oh god. Someone better warm up the cat scanners and have the Methyl Pred on standby
Impressive results. Let's hope it's affordable and deliverable.
Impressive results. Let's hope it's affordable and deliverable.
This is the sort of thing I do to lose half an hour of a Saturday!
youtu.be/UAT-eOzeY4M?...
Fascinating.
I feel @paulb3964.bsky.social will either love this, or say surely we all already know it's not a phonetic alphabet and doesn't belong to NATO!
youtu.be/UAT-eOzeY4M?...
Fascinating.
I feel @paulb3964.bsky.social will either love this, or say surely we all already know it's not a phonetic alphabet and doesn't belong to NATO!
The genius logic of the NATO phonetic alphabet
YouTube video by RobWords
youtu.be
October 18, 2025 at 11:31 AM
This is the sort of thing I do to lose half an hour of a Saturday!
youtu.be/UAT-eOzeY4M?...
Fascinating.
I feel @paulb3964.bsky.social will either love this, or say surely we all already know it's not a phonetic alphabet and doesn't belong to NATO!
youtu.be/UAT-eOzeY4M?...
Fascinating.
I feel @paulb3964.bsky.social will either love this, or say surely we all already know it's not a phonetic alphabet and doesn't belong to NATO!
Reposted by ShinyBlackShoe (Calum Polwart)
✨#ESMO25✨
🚨BREAKING: Phase 3 Data!
📈 Osimertinib + chemotherapy significantly improved overall survival vs. Osimertinib alone in patients with EGFR-mutated advanced NSCLC.
✅ Reinforces its potential as a new first-line standard of care.
🔗 Read more: bit.ly/ONCOnews18O-1
🚨BREAKING: Phase 3 Data!
📈 Osimertinib + chemotherapy significantly improved overall survival vs. Osimertinib alone in patients with EGFR-mutated advanced NSCLC.
✅ Reinforces its potential as a new first-line standard of care.
🔗 Read more: bit.ly/ONCOnews18O-1
October 18, 2025 at 9:51 AM
✨#ESMO25✨
🚨BREAKING: Phase 3 Data!
📈 Osimertinib + chemotherapy significantly improved overall survival vs. Osimertinib alone in patients with EGFR-mutated advanced NSCLC.
✅ Reinforces its potential as a new first-line standard of care.
🔗 Read more: bit.ly/ONCOnews18O-1
🚨BREAKING: Phase 3 Data!
📈 Osimertinib + chemotherapy significantly improved overall survival vs. Osimertinib alone in patients with EGFR-mutated advanced NSCLC.
✅ Reinforces its potential as a new first-line standard of care.
🔗 Read more: bit.ly/ONCOnews18O-1
Reposted by ShinyBlackShoe (Calum Polwart)
The threshold that #NICE uses to approve the use of medicines on the #NHS hasn’t increased for two decades — this may need to change to ensure patients are able to access new, effective medicines. #JoannaRobertson reports
Is the government’s pricing dispute with industry affecting medicines access for patients?
The NHS currently pays relatively low prices for medicines, with thousands of individual pharmacy purchasers driving down the cost of generics and the National Institute for Health and Care…
buff.ly
October 18, 2025 at 10:01 AM
The threshold that #NICE uses to approve the use of medicines on the #NHS hasn’t increased for two decades — this may need to change to ensure patients are able to access new, effective medicines. #JoannaRobertson reports
Reposted by ShinyBlackShoe (Calum Polwart)
New to the e-library:
A Beginner’s Guide to Targeted Cancer Treatments and Cancer Immunotherapy - 2nd ed. (2025)
Head to https://ow.ly/rqaC50X9UPi under ‘Immune System and Malignant Disease’
#RPSLibrary
A Beginner’s Guide to Targeted Cancer Treatments and Cancer Immunotherapy - 2nd ed. (2025)
Head to https://ow.ly/rqaC50X9UPi under ‘Immune System and Malignant Disease’
#RPSLibrary
October 17, 2025 at 8:30 AM
New to the e-library:
A Beginner’s Guide to Targeted Cancer Treatments and Cancer Immunotherapy - 2nd ed. (2025)
Head to https://ow.ly/rqaC50X9UPi under ‘Immune System and Malignant Disease’
#RPSLibrary
A Beginner’s Guide to Targeted Cancer Treatments and Cancer Immunotherapy - 2nd ed. (2025)
Head to https://ow.ly/rqaC50X9UPi under ‘Immune System and Malignant Disease’
#RPSLibrary
Reposted by ShinyBlackShoe (Calum Polwart)
The popular Introduction to Cancer Course is coming to Glasgow🏴in March 2026
📅 Thu 26th & Fri 26th March
🗺️ Glasgow
💡 New refreshed agenda
💷 £50/day
❗️ Save the date #BOPAITC
bopa.org.uk/save-the-dat...
📅 Thu 26th & Fri 26th March
🗺️ Glasgow
💡 New refreshed agenda
💷 £50/day
❗️ Save the date #BOPAITC
bopa.org.uk/save-the-dat...
October 13, 2025 at 1:09 PM
The popular Introduction to Cancer Course is coming to Glasgow🏴in March 2026
📅 Thu 26th & Fri 26th March
🗺️ Glasgow
💡 New refreshed agenda
💷 £50/day
❗️ Save the date #BOPAITC
bopa.org.uk/save-the-dat...
📅 Thu 26th & Fri 26th March
🗺️ Glasgow
💡 New refreshed agenda
💷 £50/day
❗️ Save the date #BOPAITC
bopa.org.uk/save-the-dat...
I don't often look in my spam folders. To be honest NHS mail does such a good job I rarely have to. I just looked in my Gmail. It's mostly full of legitimate marketing emails. To me that's not spam...
...I might never read them... But I don't think Google should delete them...
...I might never read them... But I don't think Google should delete them...
October 12, 2025 at 8:25 AM
I don't often look in my spam folders. To be honest NHS mail does such a good job I rarely have to. I just looked in my Gmail. It's mostly full of legitimate marketing emails. To me that's not spam...
...I might never read them... But I don't think Google should delete them...
...I might never read them... But I don't think Google should delete them...
If the 🇺🇸 government doesn't believe in Climate change I cants see them doing anything with this.
Which is interesting as you'd think big pharma will be knocking down their door to get them to use more expensive meds.. and clearly they are all in pharma's pocket
Which is interesting as you'd think big pharma will be knocking down their door to get them to use more expensive meds.. and clearly they are all in pharma's pocket
From 2014 to 2024, 1.6 billion inhalers for #asthma and #COPD dispensed in the US generated 24.9 million metric tons of CO₂e, with metered-dose inhalers responsible for 98% of emissions and $5.7 billion in social costs.
ja.ma/4pY0tTv
ja.ma/4pY0tTv
October 11, 2025 at 2:06 PM
If the 🇺🇸 government doesn't believe in Climate change I cants see them doing anything with this.
Which is interesting as you'd think big pharma will be knocking down their door to get them to use more expensive meds.. and clearly they are all in pharma's pocket
Which is interesting as you'd think big pharma will be knocking down their door to get them to use more expensive meds.. and clearly they are all in pharma's pocket
Interesting. We had a paper about this on the list for our #BOPA2025 @bopa.org.uk journal club last week... In the end we limited ourselves to 4 papers and this one just missed the cut.
I'd never heard of Duffy null till the paper was added to the Journal Club potential discussion...
I'd never heard of Duffy null till the paper was added to the Journal Club potential discussion...
Absolute neutrophil count–based eligibility criteria in cancer trials disproportionately exclude Black patients with the Duffy null phenotype, suggesting the need for Duffy status–specific thresholds to improve trial equity.
ja.ma/48mmCoo
ja.ma/48mmCoo
October 11, 2025 at 2:02 PM
Interesting. We had a paper about this on the list for our #BOPA2025 @bopa.org.uk journal club last week... In the end we limited ourselves to 4 papers and this one just missed the cut.
I'd never heard of Duffy null till the paper was added to the Journal Club potential discussion...
I'd never heard of Duffy null till the paper was added to the Journal Club potential discussion...
I would love to know if anyone other than council leaders think these signs cause confusion!
I'm not sure " is the right symbology for transport signs and that upsets me more!
(4m boat width restriction could confuse if width is actually <4m. They probably checked)
www.bbc.co.uk/news/article...
I'm not sure " is the right symbology for transport signs and that upsets me more!
(4m boat width restriction could confuse if width is actually <4m. They probably checked)
www.bbc.co.uk/news/article...
Chelmsford tongue-in-cheek signs must end, says Essex Highways
A council says the prank signs could
www.bbc.co.uk
October 11, 2025 at 1:52 PM
I would love to know if anyone other than council leaders think these signs cause confusion!
I'm not sure " is the right symbology for transport signs and that upsets me more!
(4m boat width restriction could confuse if width is actually <4m. They probably checked)
www.bbc.co.uk/news/article...
I'm not sure " is the right symbology for transport signs and that upsets me more!
(4m boat width restriction could confuse if width is actually <4m. They probably checked)
www.bbc.co.uk/news/article...
Reposted by ShinyBlackShoe (Calum Polwart)
I thought this was funny and wanted to share it with you.
October 9, 2025 at 3:24 PM
I thought this was funny and wanted to share it with you.
#BOPA2025 Day 3 summary
1. Elaine Vickers despite being blown off, thinks our next big things will be RAS inhibitors, protein degraders and vaccines. Two of them at least might be useful in pancreatic cancer which could really do with a boost
1. Elaine Vickers despite being blown off, thinks our next big things will be RAS inhibitors, protein degraders and vaccines. Two of them at least might be useful in pancreatic cancer which could really do with a boost
October 5, 2025 at 3:31 PM
#BOPA2025 Day 3 summary
1. Elaine Vickers despite being blown off, thinks our next big things will be RAS inhibitors, protein degraders and vaccines. Two of them at least might be useful in pancreatic cancer which could really do with a boost
1. Elaine Vickers despite being blown off, thinks our next big things will be RAS inhibitors, protein degraders and vaccines. Two of them at least might be useful in pancreatic cancer which could really do with a boost
Not sure which workshop to attend at #BOPA2025 this morning?
Ever been to a Journal Club and not known what to do? Never been to a Journal Club at all...? Come for a chat through 4 papers with friends. Hopefully build confidence/ skills reading 🗞️
⏰10:30📍Meeting Room 1
#JournalClub
Ever been to a Journal Club and not known what to do? Never been to a Journal Club at all...? Come for a chat through 4 papers with friends. Hopefully build confidence/ skills reading 🗞️
⏰10:30📍Meeting Room 1
#JournalClub
October 5, 2025 at 8:40 AM
Not sure which workshop to attend at #BOPA2025 this morning?
Ever been to a Journal Club and not known what to do? Never been to a Journal Club at all...? Come for a chat through 4 papers with friends. Hopefully build confidence/ skills reading 🗞️
⏰10:30📍Meeting Room 1
#JournalClub
Ever been to a Journal Club and not known what to do? Never been to a Journal Club at all...? Come for a chat through 4 papers with friends. Hopefully build confidence/ skills reading 🗞️
⏰10:30📍Meeting Room 1
#JournalClub
Every year the Symposia Organising Committee for #BOPA2025 books Elaine Vickers for the Sunday morning session. And every year she never fails to deliver anything but the best...
If you are still in 🛏️... It's time to get up!
Elaine's going to tell us what's coming next
If you are still in 🛏️... It's time to get up!
Elaine's going to tell us what's coming next
October 5, 2025 at 7:20 AM
Every year the Symposia Organising Committee for #BOPA2025 books Elaine Vickers for the Sunday morning session. And every year she never fails to deliver anything but the best...
If you are still in 🛏️... It's time to get up!
Elaine's going to tell us what's coming next
If you are still in 🛏️... It's time to get up!
Elaine's going to tell us what's coming next
Reposted by ShinyBlackShoe (Calum Polwart)
October 4, 2025 at 7:03 PM
Reposted by ShinyBlackShoe (Calum Polwart)
October 4, 2025 at 8:59 PM
Reposted by ShinyBlackShoe (Calum Polwart)
October 4, 2025 at 9:03 PM
Reposted by ShinyBlackShoe (Calum Polwart)
October 4, 2025 at 9:07 PM